Fas-mediated apoptosis is inhibited by TSH and iodine in moderate concentrations in primary human thyrocytes in vitro

Hormone and Metabolic Research

Volumn 31, Issue 6, 1999, Pages 355-358

  Feldkamp, J ^a   Pascher, E ^a   Perniok, A ^a   Scherbaum, W A ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Apoptosis; Fas; Iodine; Thyrocytes; TSH

Indexed keywords

FAS ANTIGEN; FAS LIGAND; GAMMA INTERFERON; IMMUNOGLOBULIN M; IODINE; THYROTROPIN;

APOPTOSIS; ARTICLE; CELL COUNT; CELL CULTURE; CELL FUNCTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; GOITER; HUMAN; HUMAN CELL; HUMAN TISSUE; IODINE DEFICIENCY; OLIGOMERIZATION; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN CROSS LINKING; RECEPTOR BINDING; THYROID CELL;

EID: 0032986250     PISSN: 00185043     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-978753     Document Type: Article

References (28)

1. 1. Thompson CB. Apoptosis in the pathogenesis and treatment of disease. Science 1995; 267: 1456-62
2. 2. Wyllie AH, Kerr JF, Currie A. The significance of apoptosis. Int Rev Cytol 1980; 68: 251-306
3. 3. Wyllie AH. Apoptosis and carcinogenesis. Eur J Cell Biol 1997; 73: 189-97
4. 4. Shen Y, Shenk T. Viruses and apoptosis (review). Curr Opin Genet Dev 1995; 5: 105-11
5. 5. Stalder T, Hahn S, Erb P. Fas antigen is the major target molecule for CD4+ T cell-mediated cytotoxicity. J Immunol 1994; 152: 1127-33
6. 6. Wyllie AH, Morris R, Smith A, Dunlop D. Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis. J Pathol 1984; 142: 66-77
7. 7. Fadok V, Savill J, Haslett C. Different populations of macrophages use either the vitronectin receptor or the phosphatidylserine receptor to recognize and remove apoptotic cells. J Immunol 1992; 149: 4029-35
8. 8. Nagata S, Golstein P. The Fas death factor. Science 1995; 267: 1449-56
9. 9. Debatin KM, Beltinger C, Bohler T, Fellenberg J, Friesen C, Fulda S, Herr I, Los M, Scheuerpflug C, Siewerts H, Stahnke K. Regulation of apoptosis through CD95 (APO-I/Fas) receptor-ligand interaction. BiochemSocTrans 1997; 25: 405-410
10. 10. Yonehara S, Ishii A, Yonehara M. A cell-killing monoclonal antibody (antiFas) to a cell surface antigene co-down regulated with the receptor of tumor necrosis factor. J Exp Med 1989; 169: 1747-56
11. 11. Suda T, Nagata S. Purification and characterization of the Fas-ligand that induces apoptosis. J Exp Med 1994; 179: 873-9
12. 12. Alnemri ES, Livingston DJ, Nicholson DW, Salvesen G, Thornberry NA, Wong WW, Yuan J. Human ICE/CED-3 protease nomenclature [letter]. Cell 1996; 87: 171
13. 13. Nicholson D, Ali A, Thornberry NA. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 1995; 376: 37-43
14. 14. Ju ST, Panka DJ, Cui H, et al. Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation. Nature 1995; 373: 444-8
15. 15. Wang J, Taniuchi I, Maekawa Y, Howard M, Cooper MD, Watanabe T. Expression and function of Fas antigen on activated murine B cells. Eur J Immunol 1996; 26: 92-6
16. 16. Tanimoto C, Hirakawa S, Kawasaki H, Hayakawa N, Ota Z. Apoptosis in thyroid diseases: a histochemical study. Endocr J 1995; 42: 193-201
17. 17. Giordano C, Stassi G, De Maria R, Todaro M, Richiusa P, Papoff G, Ruberti G, Bagnasco M, Testi R, Galluzo A. Potential involvement of Fas and its ligand in the pathogenesis of Hashimoto's thyroiditis [see comments]. Science 1997; 275: 960-3
18. 18. Mitsiades N, Poulaki V, Kotoula V, Mastorakos G, Tseleni-Balafouta S, Koutras DA, Tsokas M. Fas/Fas ligand up-regulation and BCL-2 down-regulation may be significant in the pathogenesis of Hashimoto's thyroiditis. J Clin Endocrinol Metab 1998; 83: 2199-203
19. 19. Cheng J, Zhou T, Liu C, Shapiro JP, Brauer MJ, Kiefer MC, Barr P J, Mountz JD. Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule. Science 1994; 263: 1759-62
20. 20. Shimaoka Y, Hidaka Y, Okumura M, Takeoka K, Tada H, Amino N. Serum concentration of soluble Fas in patients with autoimmune thyroid diseases. Thyroid 1998; 8: 43-7
21. 21. Tamura M, Kimura H, Koji T, Tominaya T, Ashikawa K, Kiriyama T, Yokohama N, Yoshimura T, Eguchi K, Nakane PK, Nagataki S. Role of apoptosis of thyrocytes in a rat model of goiter. A possible involvement of Fas system. Endocrinology 1998; 139: 3646-53
22. 22. Vermes I, Haanen C, Steffens-Nakken H, Reutelingsperger C. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled annexin V. J Immunol Methods 1995; 184: 39-51
23. 23. Nicoletti I, Migliorati G, Pagliacci M, Riccardi C. A rapid and simple method for measuring thymocyte apoptosis by propidium staining and flow cytometry. J Immunol Methods 1991; 139: 271-9
24. 24. Kawakami A, Eguchi K, Matsuoka N, Tsuboi M, Kawabe Y, Ishikawa N, Ito K, Nagataki S. Thyroid-stimulating hormone inhibits Fas antigen-mediated apoptosis of human thyrocytes in vitro. Endocrinology 1996; 137: 3163-9
25. 25. Arscott PL, Knapp J, Rymaszewski M, Barton JL, Bretz JD, Thompson NW, Baker JR. Fas (APO-1, CD95)-mediated apoptosis in thyroid cells is regulated by a labile protein inhibitor. Endocrinology 1997; 138: 5019-27
26. 26. Many MC, Mestdagh C, Hove M, Denef J. In vitro study of acute toxic effects of high iodide doses in human thyroid follicles. Endocrinology 1992; 131: 621-30
27. 27. Mahmoud I, Colin I, Many MC, Denef JF. Direct toxic effect of iodide in excess on iodide-deficient thyroid glands: epithelial necrosis and inflammation associated with lipofuscic accumulation. Exp Mol Pathol 1986; 44: 259-71
28. 28. Gärtner R, Schopohl D, Schäfer S, Sugrillon A, Erdmann A, Toda S, Bechtner G. Regulation of transforming growth factor beta 1 messenger ribonucleic acid expression in porcine thyroid follicles in vitro by growth factors, iodine, or delta-iodolactone. Thyroid 1997; 7: 633-40