Major histocompatibility class II HLA-DRα gene expression in thyrocytes: Counter regulation by the class II transactivator and the thyroid y box protein

Endocrinology

Volumn 139, Issue 1, 1998, Pages 280-289

  Montani, Valeria ^a   Taniguchi, Shinichi ^a,f   Shong, Minho ^a,c,g   Suzuki, Koichi ^a,h   Ohmori, Masayuki ^a,i   Giuliani, Cesidio ^a,i   Napolitano, Giorgio ^a   Fiorentino, Bruno ^a   Reimold, Andreas M ^d   Ting, Jenny P Y ^e   Kohn, Leonard D ^a   Singer, Dinah S ^b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^e UNIVERSITY OF NORTH CAROLINA   (United States)

^f TOTTORI UNIVERSITY   (Japan)

^g Chungnam National University College of Medicine   (South Korea)

^h UNIVERSITY OF YAMANASHI   (Japan)

ⁱ UNIVERSITY OF CHIETI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 85011519643     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/endo.139.1.5673     Document Type: Article

References (57)

1. BottazzoGF, Pujol-BorrellR, HanafusaT, Feldmann M 1983 Role of aberrant HLA-DR expression and antigen presentation in induction of thyroid autoimmunity. Lancet2:1115-1119
2. ToddI, LondeiM, Pujol-BorrellR, MirakianR, FeldmannM, BottazzoGF1986HLA-D/DR expression on epithelial cells: the finger on the trigger. Ann NY Acad Sci475:241-249
3. PiccininiLA, RomanSH, DaviesTF1987Autoimmune thyroid disease and thyroid cell class II major histocompatibility complex antigens. Clin Endocrinol (Oxf)26:253-272
4. ShimojoN, KohnoY, YamaguchiK-I, KikuokaS-I, HoshiokaA, NiimiH, HiraiA, TamuraY, SaitoY, KohnLD, Tahara K1996 Induction of Graves'-like disease in mice by immunization with fibroblasts transfected with the thyrotropin receptor and a class II molecule. Proc Natl Acad Sci USA93:11074-11079
5. TingJP-Y, BaldwinAS1993Regulation of MHC gene expression. Curr Opin Immunol5:8-16
6. ReithW, SteimleV, DurandB, KobrM, Mach B 1995 Regulation of MHC class II gene expression.Immunobiology193:248-253
7. PlatzerM, NeufeldDS, PiccininiLA, DaviesTF1987Induction of rat thyroid cell MHC class II antigen by thyrotropin and gamma interferon.Endocrinology121:2087-2092
8. MisakiT, TramontanoD, Ingbar S 1988 Effects of rat gamma and non-gamma interferons on the expression of la antigen, growth, and differentiated functions of FRTL-5 cells. Endocrinology123:2849-2855
9. ZakarijaM, HomicekFJ, LevisS, McKenzieJM1988Effects of gamma interferon and tumor necrosis factor alpha on thyroid cells: induction of class II antigen and inhibition of growth stimulation. Mol Cell Endocrinol58:329-336
10. ToddI, Pujol-BorrellR, HammondLJ, BottazzoGF, FeldmannM1985Interferon-gamma induces HLA-DR expression by thyroid epithelium. Clin Exp Immunol61:265-273
11. MontaniV, TaniguchiS-I, GiulianiC, NapolitanoG, SingerD, KohnLD1996Regulation of major histocompatibility (MHC) class II gene expression in thyroid cells. Program and Abstracts of the 10th International Congress of Endocrinology, San Francisco, CA, 1996(Abstract OR1-2, 1:43)
12. MontaniV, ShongM, TaniguchiS-I, SuzukiK, GiulianiC, NapolitanoG, SaitoM, SajiM, FiorentinoB, ReimoldAM, SingerDS, KohnLD1998Regulation of major histocompatibility class II gene expression in FRTL-5 thyrocytes: opposite effects of interferon and methimazole. Endocrinology139:290-302
13. BenoistC, MathisD1990Regulation of major histocompatibility complex class II genes: X, Y, and others letters of the alphabet. Amu Rev Immunol8:681-715
14. GlimcherLH, KaraCJ1992Sequences and factors: a guide to MHC class II transcription. Annu Rev Immunol10:13-49
15. ReimoldAM, KaraCJ, RooneyJW, GlimcherLH1993Transforming growth factor pi repression of the HLA-DRa gene is mediated by conserved proximal promoter elements. J Immunol151:4173-4182
16. ShikamaN, LyonJ, La ThangueNB1997The p300/CBP family: integrating signals with transcription factors and chromatin. Trends Cell Biol7:230-236
17. CooperDS1984Antithyroid drugs.N Engl J Med311:1353-1362
18. ReinhardtW, AppelMC, AlexS, YangXN, Bravennan LE 1989 The inhibitor effect of large doses of methimazole on iodine induced lymphocytic thyroiditis and serum thyroglobulin antibodv titers in BB/Wor rats. J Endocrinol Invest12:559-563
19. DaviesTF, WeissI, GerberMA1984Influence of methimazole on murine thyroiditis. J Clin Invest73:397-404
20. SteimleV, OttenLA, ZuffereyM, MachB1993Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (bare lymphocyte syndrome. Cell75:135-146
21. MachB, SteimleV, Martinez-SoriaE, ReithW1996Regulation of MHC class II genes: lessons from a disease. Annu Rev Immunol14:301-331
22. ChangCH, GuerderS, HongS-C, van EwijkW, Flavell RA 1996 Mice lacking the MHC class II transactivator (OITA) show tissue-specific impairment of class II expression. Immunity4:167-178
23. SteimleV, SiegristCA, MottetA, Lisowska-GrospierreB, MachB1994Regulation of MHC class II expression by interferons is mediated by the transactivator gene CIITA. Science265:106-109
24. ChangC-H, FontesJD, PeterlinBM, FlavellRA1994Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes. J Exp Med180:1367-1374
25. ChinKC, MaoC, SkinnerC, Riley JL, Wright KL, Moreno CS, Stark GR, Boss JM, Ting JPY 1994 Molecular analysis of GIB and G3A IFN-y mutants reveals that defects in CIITA or RFX result in defective class II MHC and Ii gene induction. Immunity1:687-697
26. DidierDK, SchiffenbauerJ, WoulfeSL, ZacheisM, SchwartzBD1988Characterization of the cDNA encoding a protein binding to the major histocompatibility complex class II Y box. Proc Natl Acad Sci USA85:7322-7326
27. TingJ P-Y, PainterA, Zeleznik-LeNJ, MacDonaldG, MooreTM, BrownA, SchwartzBD1994YB-1 DNA-binding protein represses interferon 7 activation of class II major histocompatibility genes. J Exp Med179:1605-1611
28. MacDonaldGH, Itoh-LindstromY, TingJP-Y1995The transcriptional regulatory protein, YB-1, promotes single-stranded regions in the DRA promoter. J Biol Chem270:3527-3533
29. OhmoriM, ShimuraH, ShimuraY, KohnLD1996A Y-Box protein is a suppressor factor which decreases thyrotropin receptor (TSHR) gene expression. Mol Endocrinol10:76-89
30. OhmoriM, ShongMH, NapolitanoG, SingerDS, KohnLD1995TSEP-1, a Y-box protein, is a negative regulator of major histocompatibility (MHC) class I, TSH receptor (TSHR) and MHC class II genes: it is a target of methimazole (MMI) action. Thyroid [Suppl 1]5:37
31. SajiM, ShongM, NapolitanoG, PalmerLA, TaniguchiS-I, OhmoriM, OhtaM, SuzukiK, KirschnerS, GiulianiC, SingerDS, KohnLD1995Regulation of major histocompatibility complex class I gene expression in thyroid cells: role of the cAMP response element-like sequence. J Biol Chem272:20096-20107
32. KohnLD, GiulianiC, MontaniV, NapolitanoG, OhmoriM, OhtaM, SajiM, SchuppertF, ShongM, SuzukiK, TaniguchiS-I, YanoK, SingerDS1995Antireceptor Immunity. In Rayner D, Champion B(eds) Thyroid Immunity. RG Landes Biomedical Publishers, Austin, TX, pp 115-170
33. KohnLD, WinandRJ1975Structure of an exophthalmos-producing factor derived from thvrotropin by partial pepsin digestion. J Biol Chem250:6503-6508
34. RileyJL, WesterheideSD, PriceJA, BrownJA, BossJM1995Activation of class II MHC genes requires both the x box region and the class II transactivator (OITA). Immunity2:533-543
35. Ambesi-ImpiombatoFS1986Fast growing thyroid cell strain. US Patent No. 4:608, 341
36. KohnLD, ValenteWA, GrollmanEF, AlojSM, VittiP1986Clinical determination and/or quantification of thyrotropin and a variety of thyroid stimulatory or inhibitor factors performed in vitro with an improved cell line FRTL-5. U.S. Patent No. 4:609, 622
37. GiulianiC, SajiM, NapolitanoG, PalmerLA, TaniguchiS-I, Shong M., Singer DS, Kohn LD 1995Hormonal modulation of major histocompatibility complex class I gene expression involves an enhancer A-binding complex consisting of fra-2 and the p50 subunit of NF- kB. J Biol Chem270:11453-11462
38. GiulianiC, SajiM, NapolitanoG, PalmerLA, TaniguchiS-I, Shong M., Singer DS, Kohn LD 1995Hormonal modulation of major histocompatibility complex class I gene expression involves an enhancer A-binding complex consisting of fra-2 and the p50 subunit of NF- kB. J Biol Chem270:11453-11462
39. De WetJR, WoodKV, DeLucaM, HelinskiDR, SubramaniS1987Firefly luciferase gene: structure and expression in mammalian cells. Mol Cell Biol7:725-737
40. GormanCM, MoffatLF, HowardBH1982Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.Mol Cell Biol2:1044-1051
41. DignamJ, LebovitzR, Roeder R 1983 Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res11:1475-1489
42. SambrookJ, FritschEF, ManiatisT1989Purification and radiolabeling of synthetic oligonucleotides. In: Molecular Cloning: A Laboratory Manual, ed. 2. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, vol 2:1123-1144
43. IkuyamaS, NillerHH, ShimuraH, AkamizuT, KohnLD1992Characterization of the 5’-flanking region of the rat thyrotropin receptor gene. Mol Endocrinol6:793-804
44. IkuyamaS, ShimuraH, HoefflerJP, KohnLD1992Role of the cyclic adenosine 3', 5'-monophosphate response element in efficient expression of the thyrotropin receptor promoter. Mol Endocrinol6:1701-1715
45. DavisLG, DibnerMD, Battey JF 1986 Plasmid DNA preparation: triton-lysozyme method. In: Basic Methods in Molecular Biologv. Elsevier, New York, pp 93-98
46. SangerF, NicklenS, CoulsonAR1977DNA sequencing with chain-termi-nating inhibitors. Proc Natl Acad Sci USA74:5463-5467
47. IsozakiO, KohnLD, KozakCA, Kimura S 1989 Thyroid peroxidase: rat cDNA sequence, chromosomal localization in mouse, and regulation of gene expression by comparison to thyroglobulin in rat FRTL-5 cells. Mol Endocrinol3:1681-1692
48. HabenerJF1990Cyclic AMP response element binding proteins: a cornucopia of transcription factors. Mol Endocrinol4:1087-1094
49. SchwartzRS, DattaSK1989Autoimmunity and autoimmune diseases. In: Paul WE(ed) Fundamental Immunology. Raven Press, New York, pp 819-866
50. BurmesterGR, JahnB, RohwerP, ZacherJ, WinchesterRJ, KaldenJR1987Differential expression of la antigens by rheumatoid synovial lining cells. J Clin Invest80:595-604
51. BottazzoGF, DeanBM, McNalllyJM, MacKayEH, SwiftPG, GambleDR1985In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas of diabetic patients. N Engl J Med313:353-360
52. WeetmanAP, McGregorAM1994Autoimmune thyroid disease: further developments in our understanding. Endocr Rev15:788-830
53. CoxPM, GodingCR1992An ATF/CREB binding motif is required for aberrant constitutive expression of the MHC class II DRa promoter and activation by SV40 T-antigen. Nucleic Acids Res20:4881-4887
54. WrightKL, VilenBJ, Itoh-LindstromY, MooreTL, LiG, CriscitielloM, CogswellP, ClarkeB, TingJP-Y1994CCAAT box binding protein NF-Y facilitates in vivo recruitment of upstream DNA binding transcription factors. EMBO J13:4042-4053
55. KinniburghAJ1989A cis-acting transcription element of the c-myc gene can assume an H-DNA conformation. Nucleic Acids Res17:7771-7778
56. KolluriR, TorreyTA, KinniburghAJ1992A CT promoter element binding protein: definition of a double-strand and a novel single-strand DNA binding motif. Nucleic Acids Res20:111-116
57. SabathDE, PodolinPL, ComberPG, Prystowsky MB 1990 cDNA cloning and characterization of interleukin 2-induced genes in a cloned T helper lymphocyte. J Biol Chem265:12671-12678