Cardiac and thermal homeostasis in the aging brown norway rat

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 63, Issue 12, 2008, Pages 1307-1313

  Gordon, Christopher J ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Core temperature; Heart beat variability; Heart rate; motor activity; Radiotelemetry

Indexed keywords

AGING; ANIMAL EXPERIMENT; ARTICLE; CARDIAC HOMEOSTASIS; CONTROLLED STUDY; CORE TEMPERATURE; ELECTROCARDIOGRAM; HEART RATE; HEART RATE VARIABILITY; HOMEOSTASIS; MALE; MOTOR ACTIVITY; NONHUMAN; PRIORITY JOURNAL; RAT; THERMAL HOMEOSTASIS;

RATTUS; RATTUS NORVEGICUS; RODENTIA;

EID: 62149144406     PISSN: 10795006     EISSN: None     Source Type: Journal    
DOI: 10.1093/gerona/63.12.1307     Document Type: Article

References (20)

1. Federal Interagency Forum on Aging-Related Statistics. Older Americans 2008: Key Indicators of Well-Being. Federal Interagency Forum on Aging-Related Statistics. Washington, DC: U.S. Government Printing Office; March 2008.
2. Cantuti-Castelvetri I, Shukitt-Hale B, Joseph JA. Neurobehavioral aspects of antioxidants in aging. Int J Dev Neurosci. 2000;18:367-381.
3. Harman D. The aging process. Proc Natl Acad Sci USA. 1981;78: 7124-7128.
4. Irigoyen MC, Moreira ED, Werner A, et al. Aging and baroreflex control of RSNA and heart rate in rats. Am J Physiol. 2000;279:R1865- R1871.
5. Zhang B, Sannajust F. Diurnal rhythms of blood pressure, heart rate, and locomotor activity in adult and old male Wistar rats. Physiol Behav. 2000;70:375-380.
6. Florez-Duquet M, McDonald RB. Cold-induced thermoregulation and biological aging. Physiol Rev. 1998;78:339-358.
7. Kenney WL, Munce TA. Aging and human temperature regulation. J Appl Physiol. 2003;95:2598-2603.
8. Cusak BJ. Pharmacokinetics in older persons. Am J Geriatr Pharmacother. 2004;2:274-302.
9. Wolden-Hanson T, Marck BT, Smith L, Matsumoto AM. Cross- sectional and longitudinal analysis of age-associated changes in body composition of male brown Norway rats: association of serum leptin levels with peripheral adiposity. J Gerontol Biol Sci. 1999;54A:B99-B107.
10. Turturro A, Witt WW, Lewis S, Hass BS, Lipman RD, Hart RW. Growth curves and survival characteristics of the animals used in the Biomarkers of Aging Program. J Gerontol Biol Sci. 1999;54A:B492-B501.
11. Gordon CJ. Temperature regulation in laboratory rodents. New York: Cambridge University Press; 1993.
12. Rikke BA, Johnson TE. Lower body temperature as a potential mechanism of life extension in homeotherms. Exp Gerontol. 2004;39:927-930.
13. th Annual Meeting of the Society of Toxicology, Seattle, Washington, March 16-20, 2008.
14. Gordon CJ, Samsam T, Oshiro W, Bushnell PJ. Cardiovascular effects of oral toluene in the rat monitored by radiotelemetry. Neurotoxicol Teratol. 2007;29:228-235.
15. Li H, Satinoff E. Changes in circadian rhythms of body temperature and sleep in old rats. Am J Physiol. 1995;269:R208-R214.
16. McDonald RB, Hoban-Higgins TM, Ruhe RC, Fuller CA, Horwitz BA. Alterations in endogenous circadian rhythm of core temperature in senescent Fischer 344 rats. Am J Physiol. 1999;276:R824-R830.
17. Kiang-Ulrich M, Horvath SM. Age-related metabolic modifications in male F344 rats. Exp Aging Res. 1984;10:89-93.
18. Horan MA, Little RA, Rothwell NJ, Stock MJ. Changes in body composition, brown adipose tissue activity and thermogenic capacity in BN/BiRij rats undergoing senescence. Exp Gerontol. 1988;23:455-161.
19. Refinetti R, Ma H, Satinoff E. Body temperature rhythms, cold tolerance, and fever in young and old rats of both genders. Exp Gerontol. 1990;25:533-543.
20. Salerian AJ, Saleri NG. Cooling core body temperature may slow down neurodegeneration. CNS Spectr. 2008;13:227-229.