Aging and human temperature regulation

Journal of Applied Physiology

Volumn 95, Issue 6, 2003, Pages 2598-2603

  Kenney, W Larry ^a   Munce, Thayne A ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Cold stress; Heat stress; Skin blood flow; Sweating; Thermoregulation

Indexed keywords

AGING; BODY TEMPERATURE; CARDIOVASCULAR RESPONSE; CIRCADIAN RHYTHM; COLD STRESS; HEAT STRESS; HEATING; HUMAN; PRIORITY JOURNAL; REVIEW; SEX DIFFERENCE; SKIN BLOOD FLOW; SWEAT GLAND FUNCTION; SWEATING; THERMODYNAMICS; THERMOGENESIS; THERMOREGULATION; VASOCONSTRICTION; ANIMAL; BLOOD FLOW; COLD; HEAT; PATHOPHYSIOLOGY; PHYSIOLOGY; STRESS;

AGING; ANIMALS; BODY TEMPERATURE; BODY TEMPERATURE REGULATION; CIRCADIAN RHYTHM; COLD; HEAT; HUMANS; REGIONAL BLOOD FLOW; STRESS;

EID: 0345276669     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.00202.2003     Document Type: Review

References (62)

1. Armstrong CG and Kenney WL. Effects of age and acclimation on responses to passive heat exposure. J Appl Physiol 75: 2162-2167, 1993.
2. Bernstein LM, Johnston LC, Ryan R, Inouye T, and Hick FK. Body composition as related to heat regulation in women. J Appl Physiol 9: 241-256, 1956.
3. Budd GM, Brotherhood JR, Hendrie AL, and Jeffery SE. Effects of fitness, fatness, and age on men's responses to whole body cooling in air. J Appl Physiol 71: 2387-2393, 1991.
4. Collins KJ, Dore C, Exton-Smith AN, Fox RH, Macdonald IC, and Woodward PM. Accidental hypothermia and impaired temperature homeostasis in the elderly. Br Med J 1: 353-356, 1977.
5. Crowe JP and Moore RE. Physiological and behavioral responses of aged men to passive heating. J Physiol 236: 43P-45P, 1974.
6. Drinkwater BL, Bedi JF, Louks AB, Roche S, and Horvath SM. Sweating sensitivity and capacity of women in relation to age. J Appl Physiol 53: 671-676, 1982.
7. Dunbar SL and Kenney WL. Effects of hormone replacement therapy on hemodynamic responses of postmenopausal women to passive heating. J Appl Physiol 89: 97-103, 2000.
8. Ellis FP, Exton-Smith AN, Foster KG, and Weiner JS. Eccrine sweating and mortality during heat waves in very young and very old persons. Ir J Med Sci 12: 815-817, 1976.
9. Evans E, Rendell M, Bartek J, Connor S, Bamisedun O, Dovgan D, and Gitter M. Thermally-induced cutaneous vasodilatation in aging. J Gerontol A Biol Sci Med Sci 48: M53-M57, 1993.
10. Falk B, Bar-Or O, Smolander J, and Frost G. Response to rest and exercise in the cold: effects of age and aerobic fitness. J Appl Physiol 76: 72-78, 1994.
11. Fennell WH and Moore RE. Responses of aged men to passive heating. J Physiol 231: 118P-119P, 1973.
12. Foster KG, Ellis FP, Dore C, Exton-Smith AN, and Weiner JS. Sweat responses in the aged. Age Ageing 5: 91-101, 1976.
13. Fox A, Woodward PM, and Exton-Smith AN. Body temperature in the elderly: a national study of physiological, social and environmental conditions. Br Med J 1: 200-206, 1973.
14. Gonzalez RR, Berglund LG, and Stolwijk JAJ. Thermoregulation in humans of different ages during thermal transients. In: Proceedings of the Satellite of 28th International Congress of Physiological Sciences. Pecs, Hungary: Pergamon, 1980, p. 357-361.
15. Horvath SM, Radcliffe CE, Hutt BK, and Spurr GB. Metabolic responses of older people to a cold environment. J Appl Physiol 8: 145-148, 1955.
16. Horvath SM and Rochelle RD. Hypothermia in the aged. Environ Health Perspect 20: 127-130, 1977.
17. Howell TH. Normal temperature in old age. Lancet i: 517-518, 1948.
18. Ingram DK, London ED, and Reynolds MA. Circadian rhythmicity and sleep: effects of aging in laboratory animals. Neurobiol Aging 3: 287-297, 1982.
19. Inoue Y, Nakao M, Araki T, and Murakami H. Regional differences in the sweating responses of older and younger men. J Appl Physiol 71: 2453-2459, 1991.
20. Inoue Y, Nakao M, Okudaira S, Ueda H, and Araki T. Seasonal variation in sweating responses of older and younger men. Eur J Appl Physiol 70: 6-12, 1995.
21. Inoue Y and Shibasaki M. Regional differences in age-related decrements of the cutaneous vascular and sweating responses to passive heating. Eur J Appl Physiol 74: 78-84, 1996.
22. Keilson L, Lambert D, Fabian D, Thebarge J, Ackerson T, Palomaki G, and Turgeon W. Screening for hypothermia in the ambulatory elderly. JAMA 254: 1781-1784, 1985.
23. Kenney WL. Thermoregulation at rest and during exercise in healthy older adults. In: Exercise and Sport Sciences Reviews, edited by Holloszy JA. Baltimore, MD: Williams & Wilkins, 1997, p. 41-76.
24. Kenney WL and Armstrong CG. Reflex peripheral vasoconstriction is diminished in older men. JAppl Physiol 80: 512-515, 1996.
25. Kenney WL and Buskirk ER. Functional consequences of sarcopenia: effects on thermoregulation. J Gerontol 20A: 78-85, 1995.
26. Kenney WL and Fowler SR. Methylcholine activated eccrine sweat gland density and output as a function of age. J Appl Physiol 65: 1082-1088, 1988.
27. Kenney WL, Morgan AL, Farquhar WB, Brooks EM, Pierzga JM, and Derr JA. Decreased active vasodilator sensitivity in aged skin. Am J Physiol Heart Circ Physiol 272: H1609-H1614, 1997.
28. Khan F, Spence VA, and Belch JJF. Cutaneous vascular responses and thermoregulation in relation to age. Clin Sci (Colch) 82: 521-528, 1992.
29. Krag CL and Koontz WB. Stability of body function in the aged. I. Effect of exposure of the body to cold. J Gerontol A Biol Sci Med Sci 5: 227-235, 1950.
30. Lybarger JA and Kilbourne EM. Hyperthermia and hypothermia in the elderly: an epidemiology review. In: Homeostatic Function and Aging, edited by Davis BB and Wood WG. New York: Raven, 1985, p. 149-156.
31. Macey SM and Schneider DF. Deaths from excessive heat and excessive cold among the elderly. Gerontologist 33: 497-500, 1993.
32. Marion GS, McGann KP, and Camp DL. Core body temperature in the elderly and factors which influence its measurement. Gerontology 37: 225-232, 1991.
33. Martin HL, Loomis JL, and Kenney WL. Maximal skin vascular conductance in subjects aged 5 to 85 yr. JAppl Physiol 79:297-301, 1995.
34. Mathew L, Purkayastha SS, Singh R, and Sen Gupta J. Influence of aging in the thermoregulatory efficiency of man. Int J Biometeorol 30: 137, 1986.
35. Minson CT, Holowatz LA, Wong BJ, Kenney WL, and Wilkins BW. Decreased nitric oxide- and axon reflex-mediated cutaneous vasodilation with age during local heating. J Appl Physiol 93: 1644-1649, 2002.
36. Minson CT, Wladkowski SL, Cardell AF, Pawelczyk JA, and Kenney WL. Age alters the cardiovascular response to direct passive heating. J Appl Physiol 84: 1323-1332, 1998.
37. Minson CT, Wladkowski SL, Pawelczyk JA, and Kenney WL. Age, splanchnic vasoconstriction, and heat stress during tilting. Am J Physiol Regul Integr Comp Physiol 276: R203-R212, 1999.
38. Monk TH, Buysse DJ, Reynolds CF, Kupfer DJ, and Houck PR. Circadian temperature rhythms of older people. Exp Gerontol 30: 455-474, 1995.
39. Montagna W and Carlisle K. Structural changes in aging human skin. J Invest Dermatol 73: 47-53, 1979.
40. Ogawa T and Ohnishi N. Trainability of sweat glands in the aged. In: Milestones in Environmental Physiology, edited by Yousef MK. The Hague: SPB Academic, 1989, p. 63-71.
41. O'Hanlon JF and Horvath SM. Changing physiological relationships in men under acute cold stress. Can J Physiol Pharmacol 48: 1-10, 1970.
42. Pandolf KB. Aging and heat tolerance at rest or during work. Exp Aging Res 17: 189-204, 1991.
43. Poehlman E. Endurance exercise in aging humans: effects on energy metabolism. In: Exercise and Sports Science Reviews Reuiezvs, edited by Holloszy JO. Baltimore, MD: Williams and Wilkins, 1994, p. 251-284.
44. Primrose WR and Smith LRN. Oral and environmental temperatures in a Scottish urban geriatric population. J Clin Exp Gerontol 42: 151-165, 1982.
45. Richardson D. Effects of age on cutaneous circulatory response to direct heat on the forearm. J Gerontol A Biol Sci Med Sci 44: M189-M194, 1989.
46. Rooke GA, Savage MV, and Brengelmann GL. Maximal skin blood flow is decreased in elderly men. JAppl Physiol 77: 11-14, 1994.
47. Rowell LB. Human cardiovascular adjustments to exercise and thermal stress. Physiol Rev 54: 75-159, 1974.
48. Salvosa CB, Payne PR, and Wheeler EF. Environmental conditions and body temperatures of elderly women living alone or in local authority homes. Br Med J ii: 656-659, 1971.
49. Sato K. The mechanism of eccrine sweat secretion. In: Perspectives in Exercise Science and Sports Medicine, edited by Gisolfi CV, Lamb DR, and Nadel ER. Dubuque, IA: Brown & Benchmark, 1993, p. 85-117.
50. Sato K and Timm D. Effect of aging on pharmacological sweating in man. In: Cutaneous Aging, edited by Klingman AM and Takase Y. Tokyo: University of Tokyo Press, 1988, p. 127-134.
51. Shiraki K, Sagawa S, Yousef MK, Konda N, and Miki K. Physiological responses of aged men to head-up tilt during heat exposure. J Appl Physiol 63: 576-581, 1987.
52. Shoenfeld Y, Udassin R, Shapiro Y, Ohri A, and Sohar E. Age and sex differences in response to short exposure to extreme dry heat. J Appl Physiol 44: 1-4, 1978.
53. Silver A, Montagna W, and Karaean I. Age and sex differences in spontaneous, adrenergic, and cholinergic human sweating. J Invest Dermatol 43: 255-256, 1964.
54. Therminarias A, Flore P, Oddou-Chirpaz MF, Gharib C, and Gauquelin G. Hormonal responses to exercise during moderate cold exposure in young vs. middle-aged subjects. J Appl Physiol 73: 1564-1571, 1992.
55. Van Someren EJ, Raymann RJ, Scherder EJ, Daanen HA, and Swaab DF. Circadian and age-related modulation of thermoreception and temperature regulation: mechanisms and functional implications. Ageing Res Rev 1: 721-778, 2002.
56. Vitiello MV, Smallwood RG, Avery DH, Pascualy RA, Martin DC, and Prinz PA. Circadian temperature rhythms in young adult and aged men. Neurobiol Aging 7: 97-100, 1986.
57. Wagner JA and Horvath SM. Cardiovascular reactions to cold exposures differ with age and gender. J Appl Physiol 58: 187-192, 1985.
58. Wagner JA and Horvath SM. Influences of age and gender on human thermoregulatory responses to cold exposures. J Appl Physiol 58: 180-186, 1985.
59. Wagner JA, Robinson S, and Marino R, P. Age and temperature regulation of humans in neutral and cold environments. J Appl Physiol 37: 562-565, 1974.
60. Weiss M, Milman B, Rosen B, Eisenstein Z, and Zimlichman R. Analysis of the diminished skin perfusion in elderly people by laser Doppler flowmetry. Age Ageing 21: 237-241, 1992.
61. Young AJ. Effects of aging on human cold tolerance. Exp Aging Res 17: 205-213, 1991.
62. Yousef MK and Golding LA. Thermal homeostasis and aging. In: Milestones in Environmental Physiology, edited by Yousef MK. The Hague: SPB Academic, 1989, p. 53-61.