Membrane glycoprotein M6B interacts with the human serotonin transporter

Journal of Molecular Neuroscience

Volumn 37, Issue 3, 2009, Pages 191-200

  Fjorback, Anja Winther ^a   Müller, Heidi Kaastrup ^a   Wiborg, Ove ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Cellular trafficking; Co immunoprecipitation; Confocal microscopy; GST pull down; Interacting protein; Surface expression; Yeast two hybrid

Indexed keywords

GLUTATHIONE TRANSFERASE; MEMBRANE PROTEIN; PROTEIN M6B; SEROTONIN TRANSPORTER; UNCLASSIFIED DRUG; GPM6A PROTEIN, HUMAN; GPM6B PROTEIN, HUMAN; NERVE PROTEIN; SEROTONIN;

ARTICLE; BIOTINYLATION; CELL MIGRATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; SEROTONIN UPTAKE; ANIMAL; CELL LINE; GENETICS; METABOLISM; PROTEIN BINDING; TWO HYBRID SYSTEM;

ANIMALS; CELL LINE; HUMANS; MEMBRANE GLYCOPROTEINS; NERVE TISSUE PROTEINS; PROTEIN BINDING; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 62149116565     PISSN: 08958696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12031-008-9092-4     Document Type: Article

References (36)

1. R. D. Blakely H. E. Berson R. T. Fremeau Jr. M. G. Caron M. M. Peek H. K. Prince, et al. 1991 Cloning and expression of a functional serotonin transporter from rat brain Nature 354 66 70 1944572 10.1038/354066a0 1:CAS:528:DyaK3sXhvVWitw%3D%3D
2. L. Celik S. Sinning K. Severinsen C. G. Hansen M. S. Møller M. Bols, et al. 2008 Binding of serotonin to the human serotonin transporter. Molecular modelling and experimental validation Journal of the American Chemical Society 130 3853 3865 18314975 10.1021/ja076403h 1:CAS:528:DC%2BD1cXis1Giu78%3D
3. B. Chanrion C. Mannoury la Cour B. Bertase M. Lerner-Natoli M. Freissmuth M. J. Millan, et al. 2007 Physical interaction between the serotonin transporter and neuronal nitric oxide synthase underlies reciprocal modulation of their activity PNAS 104 8119 8124 17452640 10.1073/pnas.0610964104 1:CAS:528:DC%2BD2sXmtFSrtb0%3D (Pubitemid 47185885)
4. J. Haase A. M. Killian F. Magnani C. Williams 2001 Regulation of the serotonin transporter by interacting proteins Biochemical Society Transactions 29 722 728 11709063 10.1042/BST0290722 1:CAS:528:DC%2BD3MXpt1CrsL8%3D
5. M. Henneke L. E. Wehner H. C. Hennies N. Preuss J. Gartner 2004 Mutation analysis of the M6b gene in patients with Pelizaeus-Merzbacher-like syndrome American Journal of Medical Genetics A 128 156 158 10.1002/ajmg.a.30068 (Pubitemid 39162938)
6. D. C. Hipolide K. M. Moreira K. B. Barlow A. A. Wilson J. N. Nobrega S. Tufik 2005 Distinct effects of sleep deprivation on binding to norepinephrine and serotonin transporters in rat brain Progress in Neuro-Psychopharmacology & Biological Psychiatry 29 297 303 10.1016/j.pnpbp.2004.11.015 1:CAS:528:DC%2BD2MXptlGjsA%3D%3D (Pubitemid 40202917)
7. B. J. Hoffman E. Mezey M. J. Brownstein 1991 Cloning of a serotonin transporter affected by antidepressants Science 254 579 580 1948036 10.1126/science.1948036 1:CAS:528:DyaK3sXpsFehsw%3D%3D
8. D. C. Jimerson M. D. Lesem W. H. Kaye A. P. Hegg T. D. Brewerton 1990 Eating disorders and depression: is there a serotonin connection? Biological Psychiatry 5 443 454 10.1016/0006-3223(90)90412-U (Pubitemid 20245642)
9. P. E. Knapp J. A. Benjamins R.P. Skoff 1996 Epigenetic factors up-regulate expression of myelin proteins in the dysmyelinating jimpy mutant mouse Journal of Neurobiology 29 2 138 150 8821173 10.1002/(SICI)1097- 4695(199602)29:2<138::AID-NEU2>3.0.CO;2-B 1:CAS:528:DyaK28XhsFWitLs%3D (Pubitemid 26032901)
10. F. Magnani C. G. Tate S. Wynne C. Williams J. Haase 2004 Partitioning of the serotonin transporter into lipid microdomains modulates transport of serotonin Journal of Biological Chemistry 279 38770 38778 15226315 10.1074/jbc.M400831200 1:CAS:528:DC%2BD2cXnt1yjsro%3D (Pubitemid 39296035)
11. O. V. Mortensen A. S. Kristensen G. Rudnick O. Wiborg 1999 Molecular cloning, expression and characterization of a bovine serotonin transporter Molecular Brain Research 71 1 120 126 10407194 10.1016/S0169-328X(99)00178-3 1:CAS:528:DyaK1MXks1Ght70%3D (Pubitemid 29320063)
12. H. K. Müller O. Wiborg J. Haase 2006 Subcellular redistribution of the serotonin transporter by secretory carrier membrane protein 2 Journal of Biological Chemistry 281 28901 28909 16870614 10.1074/jbc.M602848200 (Pubitemid 44507033)
13. D. L. Murphy A. Lerner G. Rudnick K. P. Lesch 2004 Serotonin transporter: gene, genetic disorders, and pharmacogenetics Molecular Interventions 4 109 123 15087484 10.1124/mi.4.2.8 1:CAS:528:DC%2BD2cXmsl2nurc%3D (Pubitemid 38584973)
14. N. L. Nadon S. Miller K. Draeger M. Salvaggio 1997 Myelin proteolipid DM20: evidence for function independent of myelination International Journal of Developmental Neuroscience 15 285 293 9253653 10.1016/S0736-5748(97)00009-9 1:CAS:528:DyaK2sXlsFWks7w%3D (Pubitemid 27308099)
15. K. A. Nave C. Lai F. E. Bloom R. J. Milner 1987 Splice site selection in the proteolipid protein (PLP) gene transcript and primary structure of the DM-20 protein of central nervous system myelin Proceedings of the National Academy of Sciences of the United States of America 84 5665 5669 2441390 10.1073/pnas.84.16.5665 1:CAS:528:DyaL1cXhsVSm
16. Y. Qian A. Galli S. Ramamoorthy S. Risso L. J. DeFelice R. D. Blakely 1997 Protein kinase C activation regulates human serotonin transporters in HEK-MSR-293 cells via altered cell surface expression Journal of Neuroscience 17 45 57 8987735 1:CAS:528:DyaK2sXmsVGi
17. M. W. Quick 2003 Regulating the conducting states of a mammalian serotonin transporter Neuron 40 537 549 14642278 10.1016/S0896-6273(03)00605-6 1:CAS:528:DC%2BD3sXptVylu7w%3D (Pubitemid 37494703)
18. S. Ramamoorthy A. L. Bauman K. R. Moore H. Han T. Yang-Feng A. S. Chang, et al. 1993 Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization Proceedings of the National Academy of Sciences of the United States of America 90 2542 2546 7681602 10.1073/pnas.90.6.2542 1:CAS:528:DyaK3sXkvV2gsrs%3D
19. S. Ramamoorthy R. D. Blakely 1999 Phosphorylation and sequestration of serotonin transporters differentially modulated by psychostimulants Science 285 763 766 10427004 10.1126/science.285.5428.763 1:CAS:528:DyaK1MXltVegsrw%3D (Pubitemid 29484550)
20. G. Rudnick J. Clark 1993 From Synapse to Vesicle - the Reuptake and Storage of Biogenic-Amine Neurotransmitters Biochimica et Biophysica Acta 1144 249 263 8104483 10.1016/0005-2728(93)90109-S 1:CAS:528:DyaK2cXitlGqsw%3D%3D (Pubitemid 23290252)
21. P. Schloss D. C. Williams 1998 The serotonin transporter: a primary target for antidepressant drugs Journal of Psychopharmacology 12 115 121 9694022 10.1177/026988119801200201 1:CAS:528:DyaK1cXltFGmt7c%3D (Pubitemid 28312567)
22. A. Serretti R. Calati L. Mandelli D. De Ronchi 2006 Serotonin transporter gene variants and behavior: a comprehensive review Current Drug Targets 7 1659 1669 17168841 10.2174/138945006779025419 1:CAS:528:DC%2BD28XhtlSisrnK (Pubitemid 44873728)
23. N. Shimokawa M. Miura 2000 Rhombex-29, a novel gene of the PLP/DM20-M6 family cloned from rat medulla oblongata by differential display Journal of Neuroscience Research 62 1 8 11002282 10.1002/1097-4547(20001001)62:1<1::AID- JNR1>3.0.CO;2-K 1:CAS:528:DC%2BD3cXnsVSgtLk%3D (Pubitemid 30765725)
24. A. Sidhu C. Wersinger P. Vernier 2004 Alpha-Synuclein regulation of the dopaminergic transporter: a possible role in the pathogenesis of Parkinson's disease FEBS Letters 565 1 5 15135042 10.1016/j.febslet.2004.03.063 1:CAS:528:DC%2BD2cXjvVGkt7c%3D (Pubitemid 38595310)
25. M. Simons E. M. Kramer P. Macchi S. Rathke-Hartlieb J. Trotter K. A. Nave, et al. 2002 Overexpression of the myelin proteolipid protein leads to accumulation of cholesterol and proteolipid protein in endosomes/lysosomes: implications for Pelizaeus-Merzbacher disease Journal of Cell Biology 157 327 336 11956232 10.1083/jcb.200110138 1:CAS:528:DC%2BD38XivFKktLc%3D (Pubitemid 34839828)
26. M. Tatsumi K. Jansen R. D. Blakely E. Richelson 1999 Pharmacological profile of neuroleptics at human monoamine transporters European Journal of Pharmacology 368 277 283 10193665 10.1016/S0014-2999(99)00005-9 1:CAS:528:DyaK1MXhs1OitLk%3D (Pubitemid 29117150)
27. G. E. Torres 2006 The dopamine transporter proteome Journal of Neurochemistry 97 3 10 16635244 10.1111/j.1471-4159.2006.03719.x 1:CAS:528:DC%2BD28XksVyksb4%3D
28. G. R. Uhl 1992 Neurotransmitter transporters (plus): a promising new gene family Trends in Neurosciences 15 265 268 1381123 10.1016/0166-2236(92)90068-J 1:CAS:528:DyaK38XlsVCnsrg%3D
29. D. A. Vouyiouklis H. Werner I. R. Griffiths G. J. Stewart K. Armin-Nave C. E. Thomson 1998 Molecular cloning and transfection studies of M6b-2, a novel splice variant of a member of the PLP-DM20/M6 gene family Journal of Neuroscience Research 52 633 640 9669312 10.1002/(SICI)1097-4547(19980615)52: 6<633::AID-JNR2>3.0.CO;2-9 1:CAS:528:DyaK1cXktFWntL0%3D (Pubitemid 28300043)
30. H. Werner L. Dimou M. Klugmann S. Pfeiffer K. A. Nave 2001 Multiple splice isoforms of proteolipid M6B in neurons and oligodendrocytes Molecular and Cellular Neurosciences 18 593 605 11749036 10.1006/mcne.2001.1044 1:CAS:528:DC%2BD3MXptFegtbw%3D (Pubitemid 34060142)
31. C. Wersinger A. Jeannotte A. Sidhu 2006 Attenuation of the norepinephrine transporter activity and trafficking via interactions with alpha-synuclein European Journal of Neuroscience 24 3141 3152 17156375 10.1111/j.1460-9568.2006. 05181.x (Pubitemid 44952646)
32. C. Wersinger M. Rusnak A. Sidhu 2006 Modulation of the trafficking of the human serotonin transporter by human alpha-synuclein European Journal of Neuroscience 24 55 64 16882008 10.1111/j.1460-9568.2006.04900.x (Pubitemid 44050666)
33. C. Wersinger A. Sidhu 2005 Disruption of the interaction of alpha-synuclein with microtubules enhances cell surface recruitment of the dopamine transporter Biochemistry 44 13612 13624 16216085 10.1021/bi050402p 1:CAS:528:DC%2BD2MXhtVarur3J (Pubitemid 41443689)
34. D. F. Wu T. Koch Y. Liang R. Stumm S. Schulz H. Schröder, et al. 2007 Membrane glycoprotein M6A interacts with the m-opioid receptor and facilitates receptor endocytosis and recycling Journal of Biological Chemistry 282 22239 22247 17548356 10.1074/jbc.M700941200 1:CAS:528:DC%2BD2sXotVGltr8%3D (Pubitemid 47195768)
35. A. Yamashita S. K. Singh T. Kawate Y. Jin E. Gouaux 2005 Crystal structure of a bacterial homologue of Na+/Cl-dependent neurotransmitter transporters Nature 473 215 222 10.1038/nature03978 (Pubitemid 41294479)
36. Y. Yan V. Narayanan C. Lagenaur 1996 Expression of members of the proteolipid protein gene family in the developing murine central nervous system Journal of Comparative Neurology 370 465 478 8807448 10.1002/(SICI)1096- 9861(19960708)370:4<465::AID-CNE4>3.0.CO;2-2 1:STN:280:BymH3c7gslY%3D (Pubitemid 26230632)