Apolipoprotein A-I conformation markedly influences HDL interaction with scavenger receptor BI

Journal of Lipid Research

Volumn 42, Issue 2, 2001, Pages 309-313

  De Beer, M C ^a   Durbin, D M ^a   Cai, L ^a   Jonas, A ^a   De Beer, F C ^a   Van der Westhuyzen, D R ^a  

^a UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

Author keywords

CLA I; High density lipoprotein; Reconstituted HDL; Scavenger receptor class BI

Indexed keywords

APOLIPOPROTEIN A1; CHOLESTEROL ESTER; HIGH DENSITY LIPOPROTEIN; PHOSPHATIDYLCHOLINE; SCAVENGER RECEPTOR;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CHO CELL; CONCENTRATION RESPONSE; CONFORMATION; NONHUMAN; PRIORITY JOURNAL;

ANTIGENS, CD36; APOLIPOPROTEIN A-I; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; LIPOPROTEINS, HDL; MEMBRANE PROTEINS; PARTICLE SIZE; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, IMMUNOLOGIC; RECEPTORS, LIPOPROTEIN; RECEPTORS, SCAVENGER; RECOMBINANT PROTEINS; SCAVENGER RECEPTORS, CLASS B;

EID: 0035091957     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Charting the fate of the good cholesterol: Identification and characterization of the high-density lipoprotein receptor SR-BI
2. Scavenger receptor BI and cholesterol trafficking
3. Dissociation of tissue uptake of cholesterol ester from that of apoA-I of rat plasma high density lipoprotein: Selective delivery of cholesterol ester to liver, adrenal, and gonad
4. Metabolism of HDL-cholesteryl ester in the rat, studied with a non-hydrolyzable analog, cholesteryl linoleyl ether
5. A nonendocytic mechanism for the selective uptake of high density lipoprotein-associated cholesterol esters
6. Identification of scavenger receptor SR-BI as a high density lipoprotein receptor
7. Apolipoproteins of HDL can directly mediate binding to the scavenger receptor SR-BI, and HDL receptor that mediates selective lipid uptake
8. Binding and cross-linking studies show that scavenger receptor BI interacts with multiple sites in apolipoprotein A-I and identify the class A amphipathic alpha-helix as a recognition motif
9. SR-BII, an isoform of the scavenger receptor BI containing an alternate cytoplasmic tail, mediates lipid transfer between high density lipoprotein and cells
10. Micellar complexes of human apolipoprotein A-I with phosphatidylcholines and cholesterol prepared from cholate-lipid dispersions
11. Reconstitution of high-density lipoproteins
12. The metabolism of very low density lipoproteins
13. Selective uptake of low density associated cholesteryl esters by human fibroblasts, human HepG2 hepatoma cells and J774 macrophages in culture
14. Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme
15. Binding of high density lipoprotein (HDL) and discoidal reconstituted HDL to the HDL receptor scavenger receptor class B type I. Effect of lipid association and APOA-I mutations on receptor binding
16. Mechanism of scavenger receptor class B type I-mediated selective uptake of cholesteryl esters from high density lipoprotein to adrenal cells
17. Synthetic high density lipoprotein particles. Application to studies of the apoprotein specificity for selective uptake of cholesterol esters
18. Apolipoprotein A-I structure and lipid properties in homogeneous, reconstituted spherical and discoidal high density lipoproteins
19. High yield overexpression and characterization of human recombinant proapolipoprotein A-I
20. Defined apolipoprotein A-I conformations in reconstituted high density lipoprotein discs
21. Apolipoprotein A-I: Structure-function relationships