Formation and Metabolism of Prebeta-Migrating, Lipid-Poor Apolipoprotein A-I

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 24, Issue 3, 2004, Pages 421-428

  Rye, Kerry Anne ^a   Barter, Philip J ^a  

^a HEART RESEARCH INSTITUTE   (Australia)

Author keywords

apoA I; CETP; HDL remodeling; PLTP; Prebeta HDL

Indexed keywords

ABC TRANSPORTER; APOLIPOPROTEIN A1; APOLIPOPROTEIN A2; CHOLESTEROL; CHOLESTEROL ESTER TRANSFER PROTEIN; HIGH DENSITY LIPOPROTEIN; LIPID; LIVER TRIACYLGLYCEROL LIPASE; PHOSPHOLIPID; PHOSPHOLIPID TRANSFER PROTEIN; VERY LOW DENSITY LIPOPROTEIN;

EXTRACELLULAR SPACE; LIPID COMPOSITION; LIPOPROTEIN METABOLISM; PRIORITY JOURNAL; PROTEIN TRANSPORT; SHORT SURVEY;

APOLIPOPROTEIN A-I; APOLIPOPROTEIN A-II; ATP-BINDING CASSETTE TRANSPORTERS; BILE; CARRIER PROTEINS; CHOLESTEROL; CHOLESTEROL ESTER TRANSFER PROTEINS; GLYCOPROTEINS; HUMANS; LIPASE; LIPOPROTEINS, HDL; LIPOPROTEINS, VLDL; LIVER; MEMBRANE PROTEINS; PHOSPHOLIPID TRANSFER PROTEINS; PHOSPHOLIPIDS; RECEPTORS, IMMUNOLOGIC; RECEPTORS, SCAVENGER; TRIGLYCERIDES;

EID: 1542283778     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000104029.74961.f5     Document Type: Short Survey

References (71)

1. Gordon DJ, Knoke J, Probstfield JL, Superko R, Tyroler HA. High-density lipoprotein cholesterol and coronary heart disease in hypercholesterolemic men: the Lipid Research Clinics Coronary Primary Prevention Trial. Circulation. 1986;74:1217-1225.
2. Enger SC, Hjermann I, Foss OP, Helgeland A, Holme I, Leren P, Norum KR. High density lipoprotein cholesterol and myocardial infarction or sudden coronary death: a prospective case-control study in middle-aged men of the Oslo study. Artery. 1979;5:170-181.
3. Miller NE, Thelle DS, Forde OH, Mjos OD. The Tromso heart-study. High density lipoprotein and coronary heart-disease: a prospective case-control study. Lancet. 1977;1:965-968.
4. Goldbourt U, Medalie JH. High density lipoprotein cholesterol and incidence of coronary heart disease: the Israeli Ischemic Heart Disease Study. Am J Epidemiol. 1979;109:296-308.
5. Gordon T, Castelli WP, Hjortland MC, Kannel WB, Dawber TR. High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study. Am J Med. 1977;62:707-714.
6. Jacobs DR, Jr., Mebane IL, Bangdiwala SI, Criqui MH, Tyroler HA. High density lipoprotein cholesterol as a predictor of cardiovascular disease mortality in men and women: the follow-up study of the Lipid Research Clinics Prevalence Study. Am J Epidemiol. 1990;131:32-47.
7. Miller M, Seidler A, Kwiterovich PO, Pearson TA. Long-term predictors of subsequent cardiovascular events with coronary artery disease and 'desirable' levels of plasma total cholesterol. Circulation. 1992;86:1165-1170.
8. Pekkanen J, Linn S, Heiss G, Suchindran CM, Leon A, Rifkind BM, Tyroler HA. Ten-year mortality from cardiovascular disease in relation to cholesterol level among men with and without preexisting cardiovascular disease. N Engl J Med. 1990;322:1700-1707.
9. Fielding CJ, Fielding PE. Molecular physiology of reverse cholesterol transport. J Lipid Res. 1995;36:211-228.
10. Yancey PG, Bortnick AE, Kellner-Weibel G, de la Llera-Moya M, Phillips MC, Rothblat GH. Importance of different pathways of cellular cholesterol efflux. Arterioscler Thromb Vasc Biol. 2003;23:712-719.
11. Oram JF. HDL Apolipoproteins and ABCA1: partners in the removal of excess cellular cholesterol. Arterioscler Thromb Vasc Biol. 2003;23:720-727.
12. Wang N, Tall AR. Regulation and mechanism of ATP-binding cassette transporter A1-mediated cellular cholesterol efflux. Arterioscler Thromb Vasc Biol. 2003;23:1178-1184.
13. Rye KA, Clay MA, Barter PJ. Remodeling of high density lipoproteins by plasma factors. Atherosclerosis. 1999;145:227-238.
14. Jonas A, von Eckardstein A, Kezdy KE, Steinmetz A, Assmann G. Structural and functional properties of reconstituted high density lipoprotein discs prepared with six apolipoprotein A-I variants. J Lipid Res. 1991;32:97-106.
15. Nichols AV, Blanche PJ, Gong EL, Shore VG, Forte TM. Molecular pathways in the transformation of model discoidal lipoprotein complexes induced by lecithin:cholesterol acyltransferase. Biochim Biophys Acta. 1985;834:285-300.
16. Blanche PJ, Gong EL, Forte TM, Nichols AV. Characterization of human high-density lipoproteins by gradient gel electrophoresis. Biochim Biophys Acta. 1981;665:408-419.
17. Cheung MC, Albers JJ. Characterization of lipoprotein particles isolated by immunoaffinity chromatography: particles containing A-I and A-II and particles containing A-I but no A-II. J Biol Chem. 1984;259:1201-12209.
18. Cheung MC, Albers JJ. Distribution of high density lipoprotein particles with different apoprotein composition: particles with A-I and A-II and particles with A-I but no A-II. J Lipid Res. 1982;23:747-753.
19. Barrans A, Jaspard B, Barbaras R, Chap H, Perret B, Collet X. Pre-b HDL: structure and metabolism. Biochim Biophys Acta. 1996;1300:73-85.
20. Norum KR, Glomset JA, Nichols AV, Forte T. Plasma lipoproteins in familial lecithin: cholesterol acyltransferase deficiency: physical and chemical studies of low and high density lipoproteins. J Clin Invest. 1971;50:1131-1140.
21. Forte TM, Bielicki JK, Knoff L, McCall MR. Structural relationships between nascent apoA-I-containing particles that are extracellularly assembled in cell culture. J Lipid Res. 1996;37:1076-1085.
22. Asztalos B, Zhang W, Roheim PS, Wong L. Role of free apolipoprotein A-I in cholesterol efflux: formation of pre-alpha-migrating high-density lipoprotein particles. Arterioscler Thromb Vasc Biol. 1997;17:1630-1636.
23. Huang Y, von Eckardstein A, Wu S, Maeda N, Assmann G. A plasma lipoprotein containing only apolipoprotein E and with gamma mobility on electrophoresis releases cholesterol from cells. Proc Natl Acad Sci U S A. 1994;91:1834-1838.
24. Barter PJ and Rye K-A. High density lipoproteins and coronary heart disease. Atherosclerosis. 1996;121:1-12.
25. Rye K-A, Hime N, Barter PJ. The influence of sphingomyelin on the structure and function of reconstituted high density lipoproteins. J Biol Chem. 1996;271:4243-4250.
26. Kee P, Rye K-A, Taylor JL, Barrett PH, Barter PJ. Metabolism of apoA-I as lipid-free protein or as component of discoidal and spherical reconstituted HDLs: studies in wild-type and hepatic lipase transgenic rabbits. Arterioscler Thromb Vasc Biol. 2002;22:1912-1917.
27. Kunitake ST, La Sala KJ, Kane JP. Apolipoprotein A-I-containing lipoproteins with pre-beta electrophoretic mobility. J Lipid Res. 1985;26:549-555.
28. Castro GR, Fielding CJ. Early incorporation of cell-derived cholesterol into pre-beta-migrating high-density lipoprotein. Biochemistry. 1988;27:25-29.
29. O'Connor PM, Zysow BR, Schoenhaus SA, Ishida BY, Kunitake ST, Naya-Vigne JM, Duchateau PN, Redberg RF, Spencer SJ, Mark S, Mazur M, Heilbron DC, Jaaffe RB, Malloy MJ, Kane JP. Prebeta-1 HDL in plasma of normolipidemic individuals: influences of plasma lipoproteins, age, and gender. J Lipid Res. 1998;39:670-678.
30. Asztalos BF, Sloop CH, Wong L, Roheim PS. Two-dimensional electrophoresis of plasma lipoproteins: recognition of new apo A-I-containing subpopulations. Biochim Biophys Acta. 1993;1169:291-300.
31. Neary RH, Gowland E. Stability of free apolipoprotein A-I concentration in serum, and its measurement in normal and hyperlipidemic subjects. Clin Chem. 1987;33:1163-1169.
32. Miida T, Kawano M, Fielding CJ, Fielding PE. Regulation of preβ high density lipoprotein in normal plasma by cell membranes and lecithin-cholesterol acyltransferase activity. Biochemistry. 1992;31:11112-11117.
33. Miida T, Ozaki K, Murakami T, Kashiwa T, Yamadera T, Tsuda T, Inano K, Okada M. Preβ1-high density lipoprotein concentration can change low-density lipoprotein-cholesterol independent of cholesteryl ester transfer protein. Clin Chim Acta. 2000;292:69-80.
34. Ishida BY, Frolich J, Fielding CJ. Prebeta-migrating high density lipoprotein: quantitation in normal and hyperlipidemic plasma by solid phase radioimmunoassaay following electrophoretic transfer. J Lipid Res. 1987;28:778-786.
35. Daerr WH, Minzlaff U, Greten H. Quantitative determination of apolipoprotein A-I in high-density lipoproteins and 'free' apolipoprotein A-I by two-dimensional agarose gel lipoprotein-'rocket' immunoelectrophoresis of human serum. Biochim Biophys Acta. 1986;879:134-139.
36. Borresen AL, Berg K. Presence of "free" apoA-I in serum: implications for immunological quantification of HDL and its apoproteins. Artery. 1980;7:139-160.
37. Liang H-Q, Rye K-A, Barter PJ. Cycling of apolipoprotein A-I between lipid-associated and lipid-free pools. Biochim Biophys Acta. 1995;1257:31-37.
38. Hara H, Yokoyama S. Role of apolipoproteins in cholesterol efflux from macrophages to lipid microemulsion: proposal of a putative model for the pre-β-high density lipoprotein pathway. Biochemistry. 1992;31:2040-2046.
39. Dixon JL, Ginsberg HN. Hepatic synthesis of lipoproteins and apolipoproteins. Semin Liver Dis. 1992;12:364-372.
40. Danielsen EM, Hansen GH, Poulsen MD. Apical secretion of apolipoproteins from enterocytes. J Cell Biol. 1993;120:1347-1356.
41. Schaefer EJ, Wetzel MG, Bengtsson G, Scow RO, Brewer HB Jr, Olivecrona T. Transfer of human lymph chylomicron constituents to other lipoprotein density fractions during in vitro lipolysis. J Lipid Res. 1982;23:1259-1273.
42. Glickman RM, Green PHR, Lees RS, Tall A. Apoprotein A-I synthesis in normal intestinal mucosa and in Tangier disease. N Engl J Med. 1978;299:1424-1427.
43. Schonfeld G, Bell E, Alpers DH. Intestinal apoproteins during fat absorption. J Clin Invest. 1978;61:1539-1550.
44. Tall AR, Green PHR, Glickman RM, Riley JW. Metabolic fate of chylomicron, phospholipids and apoproteins in the rat. J Clin Invest. 1979;64:977-989.
45. Schaefer EJ, Jenkins LL, Brewer HB Jr. Human chylomicron apolipoprotein metabolism. Biochem Biophys Res Commun. 1978;80:405-412.
46. Barter PJ. Hugh Sinclair lecture: the regulation and remodeling of HDL by plasma factors. Atheroscler Suppl. 2002;3:39-47.
47. Huuskonen J, Olkkonen VM, Jauhiainen M, Ehnholm C. The impact of phospholipid transfer protein (PLTP) on HDL metabolism. Atherosclerosis. 2001;155:269-281.
48. Rye KA, Duong MN. Influence of phospholipid depletion on the size, structure, and remodeling of reconstituted high density lipoproteins. J Lipid Res. 2000;41:1640-1650.
49. Rye K-A, Hime NJ, Barter PJ. Evidence that CETP-mediated reductions in reconstituted high density lipoprotein size involve particle fusion. J Biol Chem. 1997;272:5953-5960.
50. Clay MA, Barter PJ. Formation of new HDL particles from lipid-free apolipoprotein A-I. J Lipid Res. 1996;7:1722-1732.
51. 2. J Biol Chem. 1994;269:11572-11577.
52. Clay MA, Newnham HH, Barter PJ. Hepatic lipase promotes a loss of apolipoprotein A-I from triglyceride-enriched human high density lipoproteins during incubation in vitro. Arterioscler Thromb. 1991;11:415-422.
53. Clay MA, Newnham HH, Forte TM, Barter PJ. Cholesteryl ester transfer protein and hepatic lipase activity promote shedding of apo A-I from HDL and subsequent formation of discoidal HDL. Biochim Biophys Acta. 1992;1124:52-58.
54. Ha YC, Barter PJ. Differences in plasma cholesteryl ester transfer activity in sixteen vertebrate species. Comp Biochem Physiol B. 1982;71:265-269.
55. Tsutsumi K, Hagi A, Inoue Y. The relationship between plasma high density lipoprotein cholesterol levels and cholesteryl ester transfer protein activity in six species of healthy experimental animals. Biol Pharm Bull. 2001;24:579-581.
56. Clay MA, Hopkins GJ, Ehnholm CP, Barter PJ. The rabbit as an animal model of hepatic lipase deficiency. Biochim Biophys Acta. 1989;1002:173-181.
57. Fan J, Wang J, Bensadoun A, Lauer SJ, Dang Q, Mahley RW, Taylor JM. Overexpression of hepatic lipase in transgenic rabbits leads to a marked reduction of plasma high density lipoproteins and intermediate density lipoproteins. Proc Natl Acad Sci U S A. 1994;91:8724-8728.
58. Rashid S, Trinh DK, Uffelman KD, Cohn JS, Rader DJ, Lewis G. Expression of human hepatic lipase in the rabbit model preferentially enhances the clearance of triglyceride-enriched versus native high-density lipoprotein apolipoprotein A-I. Circulation. 2003;107:3066-3072.
59. van Tol A. Phospholipid transfer protein. Curr Opin Lipidol. 2002;13:135-139.
60. Lusa S, Jauhiainen M, Metso J, Somerharju P, Ehnholm C. The mechanism of human plasma phospholipid transfer protein-induced enlargement of high-density lipoprotein particles: evidence for particle fusion. Biochem J. 1996;313:275-282.
61. van Haperen R, van Tol A, Vermeulen P, Jauhiainen M, van Gent T, van den Berg P, Ehnholm S, Grosveld F, van der Kamp A, de Crom R. Human plasma phospholipid transfer protein increases the antiatherogenic potential of high density lipoproteins in transgenic mice. Arterioscler Thromb Vasc Biol. 2000;20:1082-1088.
62. Jiang X, Francone OL, Bruce C, Milne R, Mar J, Walsh A, Breslow JL, Tall AR. Increased prebeta-high density lipoprotein, apolipoprotein Al, and phospholipid in mice expressing the human phospholipid transfer protein and human apolipoprotein AI transgenes. J Clin Invest. 1996;98:2373-2380.
63. Horowitz BS, Goldberg IJ, Merab J, Vanni TM, Ramakrishnan R, Ginsberg HN. Increased plasma and renal clearance of an exchangeable pool of apolipoprotein A-I in subjects with low levels of high density lipoprotein cholesterol. J Clin Invest. 1993;91:1743-1752.
64. Liang H-Q, Rye K-A, Barter PJ. Remodeling of reconstituted high density lipoproteins by lecithin: cholesterol acyltransferase. J. Lipid Res. 1996;37:1962-1970.
65. Francis GA, Knopp RH, Oram JF. Defective removal of cellular cholesterol and phospholipids by aapolipoprotein A-I in Tangier disease. J Clin Invest. 1995;96:78-87.
66. Oram JF, Lawn RM. ABCA1: the gatekeeper for eliminating excess tissue cholesterol. J Lipid Res. 2001;42:1173-1179.
67. Fielding PE, Nagao K, Hakamata H, Chimini G, Fielding CJ. A two-step mechanism for free cholesterol and phospholipid efflux from human vascular cells to apolipoprotein A-1. Biochemistry. 2000;39:14113-14120.
68. Rye K-A, Duong M, Psaltis MK, Curtiss LK, Bonnet DJ, Stocker R, Barter PJ. Evidence that phospholipids play a key role in pre-β apoA-I formation and high-density lipoprotein remodeling. Biochemistry. 2002;41:12538-12545.
69. Hennessy LK, Kunitake ST, Kane JP. Apolipoprotein A-I-containing lipoproteins, with or without apolipoprotein A-II, as progenitors of pre-beta high-density lipoprotein particles. Biochemistry. 1993;32:5759-5765.
70. Calabresi L, Lucchini A, Vecchio G, Sirtori CR, Franceschini G. Human apolipoprotein A-II inhibits the formation of pre-beta high density lipoproteins. Biochim Biophys Acta. 1996;1304:32-42.
71. Rye K-A, Wee K, Curtiss L, Bonnet D, Barter P. Apolipoproteins A-II inhibits high density lipoprotein remodeling and lipid-poor apolipoproteins A-I formation. J Biol Chem. 2003;278:22530-22536.