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Volumn 8, Issue 2, 2009, Pages 798-807

Phosphorylation site mapping of endogenous proteins: A combined MS and bioinformatics approach

Author keywords

AKT1; Mass spectrometry; Phosphorylation; Post translational modification

Indexed keywords

ANTIBODY; PROTEIN KINASE B;

EID: 61849177041     PISSN: 15353893     EISSN: None     Source Type: Journal    
DOI: 10.1021/pr8005556     Document Type: Article
Times cited : (8)

References (29)
  • 1
    • 4644335402 scopus 로고    scopus 로고
    • Systems biology, proteomics, and the future of health care: Toward predictive, preventative, and personalized medicine
    • Weston, A. D.; Hood, L. Systems biology, proteomics, and the future of health care: toward predictive, preventative, and personalized medicine. J Proteome Res 2004, 3 (2), 179-96.
    • (2004) J Proteome Res , vol.3 , Issue.2 , pp. 179-196
    • Weston, A.D.1    Hood, L.2
  • 2
    • 27744563093 scopus 로고    scopus 로고
    • State-of-the-art in phosphoproteomics
    • Reinders, J.; Sickmann, A. State-of-the-art in phosphoproteomics. Proteomics 2005, 5 (16), 4052-61.
    • (2005) Proteomics , vol.5 , Issue.16 , pp. 4052-4061
    • Reinders, J.1    Sickmann, A.2
  • 3
    • 33748310730 scopus 로고    scopus 로고
    • Phosphoprotein analysis: From proteins to proteomes
    • Delom, F.; Chevet, E. Phosphoprotein analysis: from proteins to proteomes. Proteome Sci. 2006, 4 (1), 15.
    • (2006) Proteome Sci , vol.4 , Issue.1 , pp. 15
    • Delom, F.1    Chevet, E.2
  • 6
    • 26844486610 scopus 로고    scopus 로고
    • Phosphoproteome analysis of HeLa cells using stable isotope labeling with amino acids in cell culture (SILAC)
    • Amanchy, R.; Kalume, D. E.; Iwahori, A.; Zhong, J.; Pandey, A. Phosphoproteome analysis of HeLa cells using stable isotope labeling with amino acids in cell culture (SILAC). J. Proteome Res. 2005, 4 (5), 1661-71.
    • (2005) J. Proteome Res , vol.4 , Issue.5 , pp. 1661-1671
    • Amanchy, R.1    Kalume, D.E.2    Iwahori, A.3    Zhong, J.4    Pandey, A.5
  • 7
    • 33646903914 scopus 로고    scopus 로고
    • Savitski, M. M.; Nielsen, M. L.; Zubarev, R. A. ModifiComb, a new proteomic tool for mapping substoichiometric post-translational modifications, finding novel types of modifications, and fingerprinting complex protein mixtures. Mol. Cell Proteomics 2006, 5 (5), 935-48.
    • Savitski, M. M.; Nielsen, M. L.; Zubarev, R. A. ModifiComb, a new proteomic tool for mapping substoichiometric post-translational modifications, finding novel types of modifications, and fingerprinting complex protein mixtures. Mol. Cell Proteomics 2006, 5 (5), 935-48.
  • 9
    • 0037305895 scopus 로고    scopus 로고
    • Tackling the phosphoproteome: Tools and strategies
    • Kalume, D. E.; Molina, H.; Pandey, A. Tackling the phosphoproteome: tools and strategies. Curr. Opin. Chem. Biol. 2003, 7 (1), 64-9.
    • (2003) Curr. Opin. Chem. Biol , vol.7 , Issue.1 , pp. 64-69
    • Kalume, D.E.1    Molina, H.2    Pandey, A.3
  • 10
    • 23144434356 scopus 로고    scopus 로고
    • Huang, H. D.; Lee, T. Y.; Tzeng, S. W.; Horng, J. T. KinasePhos: a web tool for identifying protein kinase-specific phosphorylation sites. Nucleic Acids Res. 2005, 33 (Web Server issue), 9.
    • Huang, H. D.; Lee, T. Y.; Tzeng, S. W.; Horng, J. T. KinasePhos: a web tool for identifying protein kinase-specific phosphorylation sites. Nucleic Acids Res. 2005, 33 (Web Server issue), 9.
  • 12
    • 0038781885 scopus 로고    scopus 로고
    • Quantitative estimates of sequence divergence for comparative analyses of mammalian genomes
    • Cooper, G. M.; Brudno, M.; Green, E. D.; Batzoglou, S.; Sidow, A. Quantitative estimates of sequence divergence for comparative analyses of mammalian genomes. Genome Res. 2003,13 (5), 813-20.
    • (2003) Genome Res , vol.13 , Issue.5 , pp. 813-820
    • Cooper, G.M.1    Brudno, M.2    Green, E.D.3    Batzoglou, S.4    Sidow, A.5
  • 16
    • 0037064005 scopus 로고    scopus 로고
    • Direct identification of tyrosine 474 as a regulatory phosphorylation site for the Akt protein kinase
    • Conus, N. M.; Hannan, K. M.; Cristiano, B. E.; Hemmings, B. A.; Pearson, R. B. Direct identification of tyrosine 474 as a regulatory phosphorylation site for the Akt protein kinase. J. Biol Chem. 2002, 277 (41), 38021-8.
    • (2002) J. Biol Chem , vol.277 , Issue.41 , pp. 38021-38028
    • Conus, N.M.1    Hannan, K.M.2    Cristiano, B.E.3    Hemmings, B.A.4    Pearson, R.B.5
  • 18
    • 0037938847 scopus 로고    scopus 로고
    • Interaction between Src and a C-terminal proline-rich motif of Akt is required for Akt activation
    • Jiang, T.; Qiu, Y. Interaction between Src and a C-terminal proline-rich motif of Akt is required for Akt activation. J. Biol Chem. 2003, 278 (18), 15789-93.
    • (2003) J. Biol Chem , vol.278 , Issue.18 , pp. 15789-15793
    • Jiang, T.1    Qiu, Y.2
  • 21
    • 33744953051 scopus 로고    scopus 로고
    • Autophospho-rylation of Akt at threonine 72 and serine 246. A potential mechanism of regulation of Akt kinase activity
    • Li, X.; Lu, Y.; Jin, W.; Liang, K.; Mills, G. B.; Fan, Z. Autophospho-rylation of Akt at threonine 72 and serine 246. A potential mechanism of regulation of Akt kinase activity. J. Biol Chem. 2006, 281 (19), 13837-13.
    • (2006) J. Biol Chem , vol.281 , Issue.19 , pp. 13837-13913
    • Li, X.1    Lu, Y.2    Jin, W.3    Liang, K.4    Mills, G.B.5    Fan, Z.6
  • 23
    • 0142091454 scopus 로고    scopus 로고
    • Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism
    • Powell, D. J.; Hajduch, E.; Kular, G.; Hundal, H. S. Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism. Mol Cell Biol 2003, 23 (21), 7794-808.
    • (2003) Mol Cell Biol , vol.23 , Issue.21 , pp. 7794-7808
    • Powell, D.J.1    Hajduch, E.2    Kular, G.3    Hundal, H.S.4
  • 24
    • 27844553839 scopus 로고    scopus 로고
    • AKT crystal structure and AKT-specific inhibitors
    • Kumar, C. C.; Madison, V. AKT crystal structure and AKT-specific inhibitors. Oncogene 2005, 24 (50), 7493-501.
    • (2005) Oncogene , vol.24 , Issue.50 , pp. 7493-7501
    • Kumar, C.C.1    Madison, V.2
  • 25
    • 0036302685 scopus 로고    scopus 로고
    • Moderate alcohol consumption induces sustained cardiac protection by activating PKC-epsilon and Akt
    • Zhou, H. Z.; Karliner, J. S.; Gray, M. O. Moderate alcohol consumption induces sustained cardiac protection by activating PKC-epsilon and Akt. Am. J. Physiol. Heart Circ. Physiol. 2002, 283 (1), 74.
    • (2002) Am. J. Physiol. Heart Circ. Physiol , vol.283 , Issue.1 , pp. 74
    • Zhou, H.Z.1    Karliner, J.S.2    Gray, M.O.3
  • 26
    • 33645644483 scopus 로고    scopus 로고
    • Protein kinase C negatively regulates Akt activity and modifies UVC-induced apo-ptosis in mouse keratinocytes
    • Li, L.; Sampat, K.; Hu, N.; Zakari, J.; Yuspa, S. H. Protein kinase C negatively regulates Akt activity and modifies UVC-induced apo-ptosis in mouse keratinocytes. J. Biol. Chem. 2006, 281 (6), 3237-43.
    • (2006) J. Biol. Chem , vol.281 , Issue.6 , pp. 3237-3243
    • Li, L.1    Sampat, K.2    Hu, N.3    Zakari, J.4    Yuspa, S.H.5
  • 27
    • 2942564430 scopus 로고    scopus 로고
    • Prediction of post-translational glycosylation and phosphorylation of proteins from the amino acid sequence
    • Blom, N.; Sicheritz-Ponten, T.; Gupta, R.; Gammeltoft, S.; Brunak, S. Prediction of post-translational glycosylation and phosphorylation of proteins from the amino acid sequence. Proteomics 2004, 4 (6), 1633-49.
    • (2004) Proteomics , vol.4 , Issue.6 , pp. 1633-1649
    • Blom, N.1    Sicheritz-Ponten, T.2    Gupta, R.3    Gammeltoft, S.4    Brunak, S.5
  • 29
    • 0037434981 scopus 로고    scopus 로고
    • Disease proteomics
    • Hanash, S. Disease proteomics. Nature 2003, 422 (6928), 226-32.
    • (2003) Nature , vol.422 , Issue.6928 , pp. 226-232
    • Hanash, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.