Field-effect devices for detecting cellular signals

Seminars in Cell and Developmental Biology

Volumn 20, Issue 1, 2009, Pages 41-48

  Poghossian, A ^a,b   Ingebrandt, S ^c   Offenhausser A ^b   Schoning M J ^a,b  

^a AACHEN UNIVERSITY OF APPLIED SCIENCES   (Germany)

^b FORSCHUNGSZENTRUM JÜLICH   (Germany)

^c UNIVERSITY OF APPLIED SCIENCES KAISERSLAUTERN   (Germany)

Author keywords

Action potential; Cell acidification; Cell FET; LAPS; Living cells; Neuron transistor hybrid

Indexed keywords

SILICON;

ACIDIFICATION; ACTION POTENTIAL; BIOENGINEERING; BIOSENSOR; CELL ADHESION; CELL COMMUNICATION; CELL METABOLISM; FIELD EFFECT TRANSISTOR; HUMAN; MICROCHIP ANALYSIS; NONHUMAN; REVIEW;

EID: 61849125278     PISSN: 10849521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.semcdb.2009.01.014     Document Type: Review

References (82)

1. Bousse L. A porous membrane-based culture substrate for localized in situ electroporation of adherent mammalian cells. Sens Actuators B 34 (1996) 270-275
2. Ziegler C. Influence of cell adhesion and spreading on impedance characteristics of cell-based sensors. Fresenius J Anal Chem 366 (2000) 552-559
3. Fromherz P. Neuroelectronic interfacing: semiconductor chips with ion channels, nerve cells, and brain. In: Wasser R. (Ed). Nanoelectronics and information technology (2003), Wiley-VCH, Berlin 781-810
4. Fromherz P. Three levels of nanoelectronic interfacing: silicon chips with ion channels, nerve cells, and brain tissue. Ann NY Acad Sci 1093 (2006) 143-160
5. Fromherz P. The neuron-semiconductor interface. In: Willner I., and Katz E. (Eds). Bioelectronics (2005), Willey-VCH, Weinheim 339-394
6. Offenhäusser A., Ingebrandt S., and Mayer D. Interfacing biology with electronic devices. Solid State Phenomena 108-109 (2005) 789-796
7. Offenhäusser A., and Knoll W. Cell-transistor hybrid systems and their potential applications. Trends Biotechnol 19 (2001) 62-66
8. Schöning M.J., and Poghossian A. Recent advances in biologically sensitive field-effect transistors (BioFETs). Analyst 127 (2002) 1137-1151
9. Poghossian A., and Schöning M.J. Silicon-based chemical and biological field-effect sensors. In: Grimes C.A., Dickey E.C., and Pishko M.V. (Eds). Encyclopedia of sensors 9 (2006), American Scientific Publishers, Stevenson Ranch 463-534
10. Schöning M.J., and Poghossian A. Bio FEDs (Field-Effect Devices): state-of-the-art and new directions. Electroanalysis 18 (2006) 1893-1900
11. Poghossian A., and Schöning M.J. Chemical and biological field-effect sensors for liquids-a status report. In: Marks R.S., Cullen D.C., Karube I., Lowe C.R., and Weetall H.H. (Eds). Handbook of biosensors and biochips (2007), Willey-VCH, Weinheim 1-17 Ch 24
12. Voelker M., and Fromherz P. Signal transmission from individual mammalian nerve cell to field-effect transistor. Small 1 (2005) 206-210
13. Ingebrandt S., Yeung C.K., Krause M., and Offenhäusser A. Neuron-transistor coupling: interpretation of individual extracellular recorded signals. Eur Biophys J 34 (2005) 144-154
14. Martinoia S., and Massobrio P. Modeling and simulation of silicon neuron-to-ISFET junction. Biosens Bioelectron 19 (2004) 1487-1496
15. Bergveld P. Development, operation and application of the ion sensitive field effect transistor as a tool for electrophysiology. IEEE Trans Biomed Eng 19 (1972) 342-351
16. Lehmann M., Baumann W., Brischwein M., Gahle H.J., Freund I., Ehret R., et al. Investigation of cell-sensor hybrid structures by focused ion beam (FIB) technology. Biosens Bioelectron 16 (2001) 195-204
17. Lorenzelli L., Margesin B., Martinoia S., Tedesco M.T., and Valle M. Bioelectrochemical signal monitoring of in-vitro cultured cells by means of an automated microsystem based on solid state sensor-array. Biosens Bioelectron 18 (2003) 621-626
18. Thedinga E., Kob A., Holst H., Keuer A., Drechsler S., Niendorf R., et al. Online monitoring of cell metabolism for studing pharmacodynamic effects. Toxicol Appl Pharmacol 220 (2007) 33-44
19. Lehmann M., and Baumann W. New insights into the nanometer-scaled cell-surface interspace by cell-sensor measurements. Exp Cell Res 305 (2005) 374-382
20. 2 sensor system based on ISFET. Sens Actuators B 115 (2006) 519-525
21. 2 sensor system based on ISFET for evaluation of the glucose dependency of the metabolic pathways in cultured cells. Sens Actuators B 134 (2008) 447-450
22. Owicki J.C., and Parce J.W. Biosensors based on the energy metabolism of living cells: the physical chemistry and cell biology of extracellular acidification. Biosens Bioelectron 7 (1992) 255-272
23. Errachid A., Zine N., Samitier J., and Bausells J. FET-based chemical sensor systems fabricated with standard technologies. Electroanalysis 16 (2004) 1843-1851
24. Castellarnau M., Zine N., Bausells J., Madrid C., Juárez A., Samitier J., et al. ISFET-based biosensor to monitor sugar metabolism in bacteria. Mater Sci Eng C 28 (2008) 680-685
25. Bergveld P. Development of an ion-sensitive solid state device for neurophysiological measurements. IEEE Trans Biomed Eng 17 (1970) 70-71
26. Bergveld P., Wiersma J., and Meertens H. Extracellular potential recordings by means of a field-effect transistor without gate metal, called Osfet. IEEE Trans Biomed Eng 23 (1976) 136-144
27. Fromherz P., Offenhäusser A., Vetter T., and Weis J. A neuron-silicon junction: a Retzius cell of the leech on an insulated-gate field-effect transistor. Science 252 (1991) 1290-1293
28. Vassanelli S., and Fromherz P. Transistor-records of excitable neurons from rat brain. Appl Phys A 66 (1998) 459-463
29. Sprössler C., Denyer M., Britland S., Knoll W., and Offenhäusser A. Electrical recordings from rat cardiac muscle cells using field-effect transistors. Phys Rev E 60 (1999) 2171-2176
30. Eversmann B., Jenkner M., Hofmann F., Paulus C., Brederlow R., Holzapfl B., et al. A 128 × 128 CMOS biosensor array for extracellular recording of neural activity. IEEE J Solid-State Circuit 38 (2003) 2306-2317
31. Lambacher A., Jenkner M., Merz M., Eversmann B., Kaul R.A., Hofmann F., et al. Electrical imaging of neuronal activity by multi-transistor-array (MTA) recording at 7.8 μm resolution. Appl Phys A 79 (2004) 1607-1611
32. Hutzler M., Lambacher A., Eversmann B., Jenkner M., Thewes R., and Fromherz P. High-resolution multitransistor array recording of electrical field potentials in cultured brain slices. J Neurophysiol 96 (2006) 1638-1645
33. Imfeld K., Neukom S., Maccione A., Bornat Y., Martinoia S., Farine P.A., et al. Large-scale, high-resolution data acquisition system for extracellular recording of electrophysiological activity. IEEE Trans Biomed Eng 55 (2008) 2064-2073
34. Peitz I., Voelker M., and Fromherz P. Recombinant serotonin receptor on a transistor as a prototype for cell-based biosensors. Angew Chem 46 (2007) 5787-5790
35. Lichtenberger J., and Fromherz P. A cell-semiconductor synapse: transistor recording of vesicle release in chromaffin cells. Biophys J 92 (2007) 2262-2268
36. Brittinger M., and Fromherz P. Field-effect transistor with recombinant potassium channels: fast and slow response by electrical and chemical interactions. Appl Phys A 81 (2005) 439-447
37. Pabst M., Wrobel G., Ingebrandt S., Sommerhage F., and Offenhäusser A. Solution of the Poisson-Nernst-Plank equation in the cell-substrate interface. Eur Phys J E 24 (2007) 1-8
38. + channels in cell adhesion probed by transistor recording. Biophys J 90 (2006) 183-189
39. Offenhäusser A, Ingebrandt S, Pabst M, Sommerhage F. Bioelectronic detection schemes for biomedical and environmental sensing. In: Macromolecules for a Safe, Sustainable and Healthy World-2nd Strategic Polymer Symposium; 2007.
40. + channels by weak capacitive currents on a silicon chip. J Neurophysiol 100 (2008) 346-357
41. Schoen I., and Fromherz P. The mechanism of extracellular stimulation of nerve cells on an electrolyte-oxide-semiconductor capacitor. Biophys J 92 (2007) 1096-1111
42. Cohen A., Shappir J., Yitzchaik S., and Spira M.E. Experimental and theoretical analysis of neuron-transistor hybrid electrical coupling: the relationships between the electro-anatomy of cultured Aplysia neurons and the recorded field potentials. Biosens Bioelectron 2 (2006) 656-663
43. Ingebrandt S., Yeung C.K., Krause M., and Offenhäusser A. Cardiomyocyte-transistor-hybrids for sensor application. Biosens Bioelectron 16 (2001) 565-570
44. Yeung C.K., Ingebrandt S., Krause M., Offenhäusser A., and Knoll W. Validation of the use of field effect transistors for extracellular signal recording in pharmacological bioassays. J Pharmacol Toxicol Methods 45 (2001) 207-214
45. Poghossian A., Ingebrandt S., Yeung C.K., Offenhäusser A., and Schöning M.J. Microsensors based on ion-sensitive field-effect transistors for biomedical applications. Biomed Technik 49 (2004) 1036-1037
46. Meyburg S., Goryll M., Moers J., Ingebrandt S., Böcker-Meffert S., Lüth H., et al. N-channel field-effect transistors with floating gates for extracellular recordings. Biosens Bioelectron 21 (2006) 1037-1044
47. Meyburg S., Stockmann R., Moers J., Offenhäusser A., and Ingebrandt S. Advanced CMOS process for floating gate field-effect transistors in bioelectronic applications. Sens Actuators B 128 (2007) 208-217
48. Cohen A., Spira M.E., Yitshaik S., Borghs G., Shwartzglass O., and Shappir J. Depletion type floating gate p-channel MOS transistor for recording action potentials generated by cultured neurons. Biosens Bioelectron 19 (2004) 1703-1709
49. Milgrew M.J., Riehle M.O., and Cumming D.R.S. A large transistor-based sensor array chip for direct extracellular imaging. Sens Actuators B 111-112 (2005) 347-353
50. Ingebrandt S., Yeung C.K., Staab W., Zetterer T., and Offenhäusser A. Backside contacted field effect transistor array for extracellular signal recording. Biosens Bioelectron 18 (2003) 429-435
51. Steinhoff G., Baur B., Wrobel G., Ingebrandt S., Offenhäusser A., Krost A., et al. Recording of cell action potentials with AlGaN/GaN field-effect transistors. Appl Phys Lett 86 (2005) 033901
52. Yu J., Jha S.K., Xiao L., Liu Q., Wang P., Surya C., et al. AlGaN/GaN heterostructures for non-invasive cell electrophysiological measurements. Biosens Bioelectron 23 (2007) 513-519
53. Wang P., Xu G., Qin L., Xu Y., Li Y., and Li R. Cell-based biosensors and its application in biomedicine. Sens Actuators B 108 (2005) 576-584
54. Park I., Li Z., Li X., Pisano A.P., and Williams R.S. Towards the silicon nanowire-based sensor for intracellular biochemical detection. Biosens Bioelectron 22 (2007) 2065-2070
55. Kim W., Ng J.K., Kunitake M.E., Conklin B.R., and Yang P. Interfacing silicon nanowires with mammalian cells. J Am Chem Soc 129 (2007) 7228-7229
56. Pearton S.J., Lele T., Tseng Y., and Ren F. Penetrating living cells using semiconductor nanowires. Trends Biotechnol 25 (2007) 481-482
57. Qi S., Yi C., Chen W., Fong C.C., Lee S.T., and Yang M. Effects of silicon nanowires on HepG2 cell adhesion and spreading. ChemBioChem 8 (2007) 1115-1118
58. Patolsky F., Timko B.P., Yu G., Fang Y., Greytak A.B., Zheng G., et al. Detection, stimulation, and inhibition of neuronal signals with high-density nanowire transistor arrays. Science 313 (2006) 1100-1104
59. Gleixner R., and Fromherz P. The extracellular electrical resistivity in cell adhesion. Biophys J 90 (2006) 2600-2611
60. Cohen A., Shappir J., Yitzchaik S., and Spira M.E. Reversible transition of extracellular field potential recordings to intracellular recordings of action potentials generated by neurons grown on transistors. Biosens Bioelectron 23 (2008) 811-819
61. Voelker M., and Fromherz P. Nyquist noise of cell adhesion detected in a neuron-silicon transistor. Phys Rev Lett 96 (2006) 228102
62. Schäfer S., Eick S., Hofmann B., Dufaux T., Stockmann R., Wrobel G., et al. Time-dependent observation of individual cellular binding events to field-effect transistors. Biosens Bioelectron 24 (2009) 1201-1208
63. Ingebrandt S., Han Y., Nakamura F., Poghossian A., Schöning M.J., and Offenhäusser A. Label-free detection of single nucleotide polymorphisms utilizing the differential transfer function of field-effect transistors. Biosens Bioelectron 22 (2007) 2834-2840
64. Weis R., Müller B., and Fromherz P. Neuron adhesion on a silicon chip probed by an array of field-effect transistors. Phys Rev Lett 76 (1996) 327-330
65. Kiessling V., Müller B., and Fromherz P. Extracellular resistance in cell adhesion measured with a transistor probe. Langmuir 16 (2000) 3517-3521
66. Owicki J.W., Bousse L.J., Hafeman D.G., Kirk G.L., Olson J.D., Wada H.G., et al. The light-addressable potentiometric sensor: principles and biological applications. Ann Rev Biophys Biomol Struct 23 (1994) 87-113
67. Hafner F. Cytosensor microphysiometer: technology and recent applications. Biosens Bioelectron 15 (2000) 149-158
68. Wagner T., and Schöning M.J. Light-addressable potentiometric sensors (LAPS): recent trends and applications. In: Alegret S., and Merkoci A. (Eds). Electrochemical sensor analysis 49 (2007), Elsevier, Amsterdam 87-128
69. Yoshinobu T., Ecken H., Poghossian A., Simonis A., Iwasaki H., Lüth H., et al. Constant-current-mode LAPS (CLAPS) for the detection of penicillin. Electroanalysis 13 (2001) 733-736
70. Stein B., George M., Gaub H.E., Behrends J.C., and Parak W.J. Spatially resolved monitoring of cellular metabolic activity with a semiconductor-based biosensor. Biosens Bioelectron 18 (2003) 31-41
71. Yoshinobu T., Ecken H., Ismail A.B.M., Iwasaki H., Lüth H., and Schöning M.J. Chemical imaging sensor and its application to biological systems. Electrochim Acta 47 (2001) 259-263
72. Schöning M.J., Wagner T., Wang C., Otto R., and Yoshinobu T. Development of a handheld 16 channel pen-type LAPS for electrochemical sensing. Sens Actuators B 108 (2005) 808-814
73. Wagner T., Yoshinobu T., Rao C., Otto R., and Schöning M.J. All-in-one solid-state device based on a light-addressable potentiometric sensor platform. Sens Actuators B 117 (2006) 472-479
74. Wagner T., Rao C., Kloock J.P., Yoshinobu T., Otto R., Keusgen M., et al. LAPS card-a novel chip card-based light-addressable potentiometric sensor (LAPS). Sens Actuators B 118 (2006) 33-40
75. Wagner T., Molina R., Yoshinobu T., Kloock J.P., Biselli M., Canzoneri M., et al. Handheld multi-channel LAPS device as a transducer platform for possible biological and chemical multi-sensor applications. Electrochim Acta 53 (2007) 305-311
76. Stein B., George M., Gaub H.E., and Parak W. Extracellular measurements of averaged ionic currents with the light-addressable potentiometric sensor (LAPS). Sens Actuators B 98 (2004) 299-304
77. Xu G., Ye X., Qin L., Xu Y., Li Y., Li R., et al. Cell-based biosensors on light-addressable potentiometric sensors for single cell monitoring. Biosens Bioelectron 20 (2005) 1757-1763
78. Liu Q., Cai H., Xu Y., Xiao L., Yang M., and Wang P. Detection of heavy metal toxicity using cardiac cell-based biosensor. Biosens Bioelectron 22 (2007) 3224-3229
79. Liu Q., Cai H., Xu Y., Li Y., Li R., and Wang P. Olfactory cell-based biosensor: a first step towards a neurochip of bioelectronic nose. Biosens Bioelectron 22 (2006) 318-322
80. Wang P., Liu Q., Xu Y., Cai H., and Li Y. Olfactory and taste cell sensor and its applications in biomedicine. Sens Actuators A 139 (2007) 131-138
81. Zhang W., Li Y., Liu Q., Xu Y., Cai H., and Wang P. A novel experimental research based on taste cell chips for taste transduction mechanism. Sens Actuators B 131 (2008) 24-28
82. Manalis S.R., Cooper E.B., Indermuhle P.F., Kernen P., Wagner P., Hafeman D.G., et al. Appl Phys Lett 76 (2000) 1072-1074