Validation of the use of field effect transistors for extracellular signal recording in pharmacological bioassays

Journal of Pharmacological and Toxicological Methods

Volumn 45, Issue 3, 2001, Pages 207-214

  Yeung, C K ^a   Ingebrandt, S ^a   Krause, M ^a   Offenhausser A ^a   Knoll, W ^a  

^a MAX PLANCK INSTITUTE FOR POLYMER RESEARCH   (Germany)

Author keywords

Bioassay; Cardiac myocytes; Extracellular recording; Field effect transistors; Heart rate; Methods; Rat

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; CARBACHOL; FIBRONECTIN; ISOPRENALINE; LAMININ; NORADRENALIN; PYROXYLIN; SDZ PCO400; SILICON; UNCLASSIFIED DRUG; VERAPAMIL;

ANIMAL CELL; ARTICLE; BIOASSAY; CELL ADHESION; CELL COMMUNICATION; CELL CULTURE; CHRONOTROPISM; CONTROLLED STUDY; DEVICE; ELECTROPHYSIOLOGY; EMBRYO; HEART MUSCLE CELL; NONHUMAN; PATCH CLAMP; RAT; RECORDING; SEMICONDUCTOR; SIGNAL TRANSDUCTION; VALIDATION PROCESS;

ACTION POTENTIALS; ANIMALS; BENZOPYRANS; BIOLOGICAL ASSAY; BIOSENSING TECHNIQUES; CARBACHOL; CARDIOVASCULAR AGENTS; CELLS, CULTURED; CYCLOPENTANES; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROCHEMISTRY; ELECTRODES; HEART; ISOPROTERENOL; MYOCARDIUM; NOREPINEPHRINE; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; SEMICONDUCTORS; TRANSISTORS; VERAPAMIL;

ANIMALIA;

EID: 0035672094     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1056-8719(01)00150-2     Document Type: Article

References (12)

1. Preliminary study on the suitability of a pharmacological bio-assay based on cardiac myocytes cultured over microfabricated microelectrode arrays
2. Bioassay development: The implications of cardiac myocytes motility in vitro
3. A neuron-silicon junction: Retzius cell of the leech on an insulated-gate field effect transistor
4. The use of neuronal networks on multielectrode arrays as biosensors
5. Extended gate electrode arrays for extracellular signal recordings
6. Carbohydrate-mediated cell adhesion to glycoproteins immobilized on nitrocellulose
7. Field-effect transistor array for monitoring electrical activity from mammalian neurons in culture
8. Electrophysiological development of embryonic hippocampal neurons from rat grown on synthetic thin films
9. Development and application of cell-based biosensors
10. Sealing cultured invertebrate neurons to embedded dish electrodes facilitates long-term stimulation and recording
11. Electrical recordings from rat cardiac muscle cells using field-effect transistors
12. Long-term recording system based on field-effect transistor arrays for monitoring electrogenic cells in culture