Regulation of thioredoxin by ceramide in retinal pigment epithelial cells

Experimental Eye Research

Volumn 88, Issue 3, 2009, Pages 410-417

  Sreekumar, Parameswaran G ^a   Ding, Yi ^a   Ryan, Stephen J ^a   Kannan, Ram ^a   Hinton, David R ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

hepatocyte growth factor; nuclear translocation; oxidant injury; thioredoxin; thioredoxin interacting protein

Indexed keywords

APOPTOSIS SIGNAL REGULATING KINASE 1; CERAMIDE; ENZYME INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSGENE; SCATTER FACTOR; THIOREDOXIN 1; THIOREDOXIN INTERACTING PROTEIN;

APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; CYTOSOL; ENZYME INHIBITION; EPITHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; HYPOXIA; NUCLEUS ACCUMBENS; OXIDATIVE STRESS; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

CARRIER PROTEINS; CELL SURVIVAL; CELLS, CULTURED; CERAMIDES; HUMANS; MAP KINASE KINASE KINASE 5; OXIDATIVE STRESS; RETINAL PIGMENT EPITHELIUM; SIGNAL TRANSDUCTION; THIOREDOXINS; TRANSLOCATION, GENETIC; UP-REGULATION;

EID: 61549113132     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2008.10.009     Document Type: Article

References (42)

1. Arai R.J., Masutani H., Yodoi J., Debbas V., Laurindo F.R., Stern A., and Monteiro H.P. Nitric oxide induces thioredoxin-1 nuclear translocation: possible association with the p21Ras survival pathway. Biochem. Biophys. Res. Commun. 348 (2006) 1254-1260
2. Badr G.A., Zhang J.Z., Tang T., Kern T.S., and Ismail-Beigi F. Glut1 and glut3 expression, but not capillary density, is increased by cobalt chloride in rat cerebrum and retina. Mol. Brain Res. 64 (1999) 24-33
3. Bai J., Nakamura H., Kwon Y.W., Hattori I., Yamaguchi Y., Kim Y.C., Kondo N., Oka S., Ueda S., Masutani H., and Yodoi J. Critical roles of thioredoxin in nerve growth factor-mediated signal transduction and neurite outgrowth in PC12 cells. J. Neurosci. 23 (2003) 503-509
4. Chen C.L., Lin C.F., Chang W.T., Huang W.C., Teng C.F., and Lin Y.S. Ceramide induces p38 MAPK and JNK activation through a mechanism involving a thioredoxin-interacting protein-mediated pathway. Blood 111 (2008) 4365-4374
5. Cheng G.C., Schulze P.C., Lee R.T., Sylvan J., Zetter B.R., and Huang H. Oxidative stress and thioredoxin-interacting protein promote intravasation of melanoma cells. Exp. Cell Res. 300 (2004) 297-307
6. Das S., Khan N., Mukherjee S., Bagchi D., Gurusamy N., Swartz H., and Das D.K. Redox regulation of resveratrol-mediated switching of death signal into survival signal. Free Radic. Biol. Med. 44 (2008) 82-90
7. Freeman R.E., and Neuzil J. Role of thioredoxin-1 in apoptosis induction by α-tocopheryl succinate and TNF-related apoptosis-inducing ligand in mesothelioma cells. FEBS Lett. 580 (2006) 2671-2676
8. Hattori I., Takagi Y., Nakamura H., Nozaki K., Bai J., Kondo N., Sugino T., Nishimura M., Hashimoto N., and Yodoi J. Intravenous administration of thioredoxin decreases brain damage following transient focal cerebral ischemia in mice. Antioxid. Redox Signal 6 (2004) 81-87
9. He P.M., He S., Garner J.A., Ryan S.J., and Hinton D.R. Retinal pigment epithelial cells secrete and respond to hepatocyte growth factor. Biochem. Biophys. Res. Commun. 249 (1998) 253-257
10. Hirota K., Matsui M., Iwata S., Nishiyama A., Mori K., and Yodoi J. AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1. Proc. Natl. Acad. Sci. U.S.A. 94 (1997) 3633-3638
11. Holmgren A. Glutaredoxin from Escherichia coli and calf thymus. Methods Enzymol. 113 (1985) 525-540
12. Inomata Y., Nakamura H., Tanito M., Teratani A., Kawaji T., Kondo N., Yodoi J., and Tanihara H. Thioredoxin inhibits NMDA-induced neurotoxicity in the rat retina. J. Neurochem. 98 (2006) 372-385
13. 3 up-regulated protein 1 mediates oxidative stress via suppressing the thioredoxin function. J. Immunol. 164 (2000) 6287-6295
14. Kajimoto T., Shirai Y., Sakai N., Yamamoto T., Matzuzaki H., Kikkawa U., and Saito N. Ceramide-induced apoptosis by translocation, phosphorylation and activation of protein kinase Cdelta at Golgi complex. J. Biol. Chem. 279 (2004) 12668-12676
15. Kang S.W., Chae H.Z., Seo M.S., Kim K., Baines I.C., and Rhee S.G. Mammalian peroxiredoxin isoforms can reduce hydrogen peroxide generated in response to growth factors and tumor necrosis factor-alpha. J. Biol. Chem. 273 (1998) 6297-6302
16. Kannan R., Jin M., Gamulescu M.A., and Hinton D.R. Ceramide-induced apoptosis: role of catalase and hepatocyte growth factor. Free Radic. Biol. Med. 37 (2004) 166-175
17. Li B., Ishii T., Tan C.P., Soh J.W., and Goff S.P. Pathways of induction of peroxiredoxin I expression in osteoblasts: roles of p38 mitogen-activated protein kinase and protein kinase C. J. Biol. Chem. 277 (2002) 12418-12422
18. Liu Y., and Min W. Thioredoxin promotes ASK1 ubiquitination and degradation to inhibit ASK1-mediated apoptosis in a redox activity-independent manner. Circ. Res. 90 (2002) 1259-1266
19. Malik G., Gorbounov N., Das S., Gurusamy N., Otani H., Maulik N., Goswami S., and Das D.K. Ischemic preconditioning triggers nuclear translocation of thioredoxin and its interaction with Ref-1 potentiating a survival signal through the PI-3-kinase-Akt pathway. Antioxid. Redox Signal 8 (2006) 2101-2109
20. Matsui M., Oshima M., Oshima H., Takaku K., Maruyama T., Yodoi J., and Taketo M.M. Early embryonic lethality caused by targeted disruption of the mouse thioredoxin gene. Dev. Biol. 178 (1996) 179-185
21. Matsumoto K., and Nakamura T. Emerging multipotent aspects of hepatocyte growth factor. J. Biochem. (Tokyo) 119 (1996) 591-600
22. Nakamura H., Nakamura K., and Yodoi J. Redox regulation of cellular activation. Annu. Rev. Immunol 15 (1997) 351-369
23. Nishiyama A., Masutani H., Nakamura H., Nishinaka Y., and Yodoi J. Redox regulation by thioredoxin and thioredoxin-binding proteins. IUBMB Life 52 (2001) 29-33
24. Nishiyama A., Matsui M., Iwata S., Hirota K., Masutani H., Nakamura H., Takagi Y., Sono H., Gon Y., and Yodoi J. Identification of thioredoxin-binding protein-2/vitamin D(3) up-regulated protein 1 as a negative regulator of thioredoxin function and expression. J. Biol. Chem. 274 (1999) 21645-21650
25. Obeid L.M., Linardic C.M., Karolak L.A., and Hannun Y.A. Programmed cell death induced by ceramide. Science 259 (1993) 1769-1771
26. Okubo K., Kosaka S., Isowa N., Hirata T., Hitomi S., Yodoi J., Nakano M., and Wada H. Amelioration of ischemia-reperfusion injury by human thioredoxin in rabbit lung. J. Thorac. Cardiovasc. Surg. 113 (1997) 1-9
27. Rouse J., Cohen P., Trigon S., Morange M., Alonso-Llamazares A., Zamanillo D., Hunt T., and Nebreda A.R. A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins. Cell 78 (1994) 1027-1037
28. Saitoh M., Nishitoh H., Fujii M., Takeda K., Tobiume K., Sawada Y., Kawabata M., Miyazono K., and Ichijo H. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK1). EMBO J. 17 (1998) 2596-2606
29. Schenk H., Klein M., Erdbrügger W., Dröge W., and Schulze-Osthoff K. Distinct effects of thioredoxin and antioxidants on the activation of transcription factors NF-kappa B and AP-1. Proc. Natl. Acad. Sci. U.S.A. 91 (1994) 1672-1676
30. Schulze P.C., De Keulenaer G.W., Yoshioka J., Kassik K.A., and Lee R.T. Vitamin D3-upregulated protein-1 (VDUP-1) regulates redox-dependent vascular smooth muscle cell proliferation through interaction with thioredoxin. Circ. Res. 91 (2002) 689-695
31. Shibuki H., Katai N., Kuroiwa S., Kurokawa T., Yodoi J., and Yoshimura N. Protective effect of adult T-cell leukemia-derived factor on retinal ischemia-reperfusion injury in the rat. Invest. Ophthalmol. Vis. Sci. 39 (1998) 1470-1477
32. Sreekumar P.G., Kannan R., Yaung J., Spee C.K., Ryan S.J., and Hinton D.R. Protection from oxidative stress by methionine sulfoxide reductases in RPE cells. Biochem. Biophys. Res. Commun. 334 (2005) 245-253
33. Takagi Y., Mitsui A., Nishiyama A., Nozaki K., Sono H., Gon Y., Hashimoto N., and Yodoi J. Overexpression of thioredoxin in transgenic mice attenuates focal ischemic brain damage. Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 4131-4136
34. Tanaka T., Hosoi F., Yamaguchi-Iwai Y., Nakamura H., Masutani H., Ueda S., Nishiyama A., Takeda S., Wada H., Spyrou G., and Yodoi J. Thioredoxin-2 (TRX-2) is an essential gene regulating mitochondria-dependent apoptosis. EMBO J 21 (2002) 1695-1703
35. Tanito M., Kwon Y.W., Kondo N., Bai J., Masutani H., Nakamura H., Fujii J., Ohira A., and Yodoi J. Cytoprotective effects of geranylgeranylacetone against retinal photooxidative damage. J. Neurosci. 25 (2005) 2396-2404
36. Tanito M., Masutani H., Nakamura H., Ohira A., and Yodoi J. Cytoprotective effect of thioredoxin against retinal photic injury in mice. Invest. Ophthalmol. Vis. Sci. 43 (2002) 1162-1167
37. Tanito M., Masutani H., Nakamura H., Oka S., Ohira A., and Yodoi J. Attenuation of retinal photooxidative damage in thioredoxin transgenic mice. Neurosci. Lett. 326 (2002) 142-146
38. Vengellur S., Woods B.J., Ryan H.E., Johnson R.S., and LaPres J.J. Gene expression profiling of the hypoxia signaling pathway in hypoxia-inducible factor 1alpha null mouse embryonic fibroblasts. Gene Exp. 11 (2003) 187-197
39. Wei S.J., Botero A., Hirota K., Bradbury C.M., Markovina S., Laszlo A., Spitz D.R., Goswami P.C., Yodoi J., and Gius D. Thioredoxin nuclear translocation and interaction with redox factor-1 activates the activator protein-1 transcription factor in response to ionizing radiation. Cancer Res. 60 (2000) 6688-6695
40. Wiegmann K., Schutze S., Machleidt T., Witte D., and Kronke M. Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling. Cell 78 (1994) 1005-1015
41. Yamamoto M., Lidia K., Gong H., Onitsuka S., Kotani T., and Ohira A. Changes in manganese superoxide dismutase expression after exposure of the retina to intense light. Histochem. J. 31 (1999) 81-87
42. Yegorova S., Liu A., and Lou M.F. Human lens thioredoxin: molecular cloning and functional characterization. Invest. Ophthalmol. Vis. Sci. 44 (2003) 3263-3271