Pioglitazone stimulates AMP-activated protein kinase signalling and increases the expression of genes involved in adiponectin signalling, mitochondrial function and fat oxidation in human skeletal muscle in vivo: A randomised trial

Diabetologia

Volumn 52, Issue 4, 2009, Pages 723-732

  Coletta, D K ^a   Sriwijitkamol, A ^b,c   Wajcberg, E ^b,c   Tantiwong, P ^b,c   Li, M ^b,c   Prentki, M ^d   Madiraju, M ^d   Jenkinson, C P ^b,e   Cersosimo, E ^b,c   Musi, N ^b,c   DeFronzo, R A ^b,c,e  

^a ARIZONA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c Texas Diabetes Institute   (United States)

^d UNIVERSITÉ DE MONTRÉAL   (Canada)

^e SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

Author keywords

Adiponectin; AMP kinase; Insulin sensitivity; Mitochondrial; Muscle; Pioglitazone

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ADIPONECTIN; ADIPONECTIN RECEPTOR 1; ADIPONECTIN RECEPTOR 2; FAT; FATTY ACID; GLUCOSE; HEMOGLOBIN A1C; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIOGLITAZONE;

ADULT; ARTICLE; CELL FUNCTION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; HYPERINSULINEMIA; IN VIVO STUDY; INSULIN SENSITIVITY; LIPID OXIDATION; MALE; MITOCHONDRION; MUSCLE BIOPSY; NON INSULIN DEPENDENT DIABETES MELLITUS; NUTRITIONAL SUPPORT; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RANDOMIZED CONTROLLED TRIAL; SKELETAL MUSCLE; VASTUS LATERALIS MUSCLE;

ADIPONECTIN; AMP-ACTIVATED PROTEIN KINASES; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; DIABETIC DIET; DNA PRIMERS; DOUBLE-BLIND METHOD; FATTY ACIDS, NONESTERIFIED; FEMALE; GENE EXPRESSION REGULATION; GLUCOSE CLAMP TECHNIQUE; HUMANS; HYPERINSULINISM; HYPOGLYCEMIC AGENTS; MALE; MALONYL COENZYME A; MIDDLE AGED; MITOCHONDRIA, MUSCLE; POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; THIAZOLIDINEDIONES;

EID: 61449222837     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-008-1256-9     Document Type: Article

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