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Volumn 46, Issue 4, 2009, Pages 482-489

Targeting cardiac sympatho-vagal imbalance using gene transfer of nitric oxide synthase

Author keywords

Autonomic imbalance; Heart rate; Hypertension; Myocardial ischemia; Nitric oxide

Indexed keywords

ANGIOTENSIN II; ENDOTHELIAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE; REACTIVE OXYGEN METABOLITE;

EID: 61449218738     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2008.12.013     Document Type: Review
Times cited : (29)

References (78)
  • 2
    • 12344330346 scopus 로고    scopus 로고
    • Elevated heart rate: a major risk factor for cardiovascular disease
    • Palatini P., and Julius S. Elevated heart rate: a major risk factor for cardiovascular disease. Clin. Exp. Hypertens. 26 7-8 (2004) 637-644
    • (2004) Clin. Exp. Hypertens. , vol.26 , Issue.7-8 , pp. 637-644
    • Palatini, P.1    Julius, S.2
  • 4
    • 0027952687 scopus 로고
    • Reduced parasympathetic cardiac control in patients with hypertension at rest and under mental stress
    • Langewitz W., Rüddel H., and Schächinger H. Reduced parasympathetic cardiac control in patients with hypertension at rest and under mental stress. Am. Heart J. 127 1 (1994) 122-128
    • (1994) Am. Heart J. , vol.127 , Issue.1 , pp. 122-128
    • Langewitz, W.1    Rüddel, H.2    Schächinger, H.3
  • 5
    • 0141453826 scopus 로고    scopus 로고
    • Early autonomic malfunction in normotensive individuals with a genetic predisposition to essential hypertension
    • Davrath L.R., Goren Y., Pinhas I., Toledo E., and Akselrod S. Early autonomic malfunction in normotensive individuals with a genetic predisposition to essential hypertension. Am. J. Physiol. Heart Circ. Physiol. 285 4 (2003) H1697-H1704
    • (2003) Am. J. Physiol. Heart Circ. Physiol. , vol.285 , Issue.4
    • Davrath, L.R.1    Goren, Y.2    Pinhas, I.3    Toledo, E.4    Akselrod, S.5
  • 8
    • 0021194420 scopus 로고
    • Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure
    • Cohn J.N., Levine T.B., Olivari M.T., Garberg V., Lura D., Francis G.S., et al. Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure. N. Engl. J. Med. 311 (1984) 819-823
    • (1984) N. Engl. J. Med. , vol.311 , pp. 819-823
    • Cohn, J.N.1    Levine, T.B.2    Olivari, M.T.3    Garberg, V.4    Lura, D.5    Francis, G.S.6
  • 9
    • 38649142128 scopus 로고    scopus 로고
    • Prediction of unexpected sudden death among healthy dogs by a novel marker of autonomic neural activity
    • Vanoli E., Adamson P.B., Foreman R.D., and Schwartz P.J. Prediction of unexpected sudden death among healthy dogs by a novel marker of autonomic neural activity. Heart Rhythm 5 2 (2008) 300-305
    • (2008) Heart Rhythm , vol.5 , Issue.2 , pp. 300-305
    • Vanoli, E.1    Adamson, P.B.2    Foreman, R.D.3    Schwartz, P.J.4
  • 10
    • 0025851674 scopus 로고
    • Vagal stimulation and prevention of sudden death in conscious dogs with a healed myocardial infarction
    • Vanoli E., De Ferrari G.M., Stramba-Badiale M., Hull Jr. S.S., Foreman R.D., and Schwartz P.J. Vagal stimulation and prevention of sudden death in conscious dogs with a healed myocardial infarction. Circ. Res. 68 5 (1991) 1471-1481
    • (1991) Circ. Res. , vol.68 , Issue.5 , pp. 1471-1481
    • Vanoli, E.1    De Ferrari, G.M.2    Stramba-Badiale, M.3    Hull Jr., S.S.4    Foreman, R.D.5    Schwartz, P.J.6
  • 11
    • 0346059329 scopus 로고    scopus 로고
    • Gene delivery of endothelial nitric oxide synthase into nucleus tractus solitarii induces biphasic response in cardiovascular functions of hypertensive rats
    • Tai M.H., Hsiao M., Chan J.Y., Lo W.C., Wang F.S., Liu G.S., et al. Gene delivery of endothelial nitric oxide synthase into nucleus tractus solitarii induces biphasic response in cardiovascular functions of hypertensive rats. Am. J. Hypertens. 17 1 (2004) 63-70
    • (2004) Am. J. Hypertens. , vol.17 , Issue.1 , pp. 63-70
    • Tai, M.H.1    Hsiao, M.2    Chan, J.Y.3    Lo, W.C.4    Wang, F.S.5    Liu, G.S.6
  • 12
    • 33750601580 scopus 로고    scopus 로고
    • Endothelial NO synthase activity in nucleus tractus solitarii contributes to hypertension in spontaneously hypertensive rats
    • Waki H., Murphy D., Yao S.T., Kasparov S., and Paton J.F. Endothelial NO synthase activity in nucleus tractus solitarii contributes to hypertension in spontaneously hypertensive rats. Hypertension 48 4 (2006) 644-650
    • (2006) Hypertension , vol.48 , Issue.4 , pp. 644-650
    • Waki, H.1    Murphy, D.2    Yao, S.T.3    Kasparov, S.4    Paton, J.F.5
  • 13
    • 0036889824 scopus 로고    scopus 로고
    • Nitric oxide and autonomic control of heart rate: a question of specificity
    • Paton J.F., Kasparov S., and Paterson D.J. Nitric oxide and autonomic control of heart rate: a question of specificity. Trends Neurosci. 25 12 (2002) 626-631
    • (2002) Trends Neurosci. , vol.25 , Issue.12 , pp. 626-631
    • Paton, J.F.1    Kasparov, S.2    Paterson, D.J.3
  • 15
    • 0028951502 scopus 로고
    • RR variability in healthy, middle-aged persons compared with patients with chronic coronary heart disease or recent acute myocardial infarction
    • Bigger Jr. J.T., Fleiss J.L., Steinman R.C., Rolnitzky L.M., Schneider W.J., and Stein P.K. RR variability in healthy, middle-aged persons compared with patients with chronic coronary heart disease or recent acute myocardial infarction. Circulation 91 7 (1995) 1936-1943
    • (1995) Circulation , vol.91 , Issue.7 , pp. 1936-1943
    • Bigger Jr., J.T.1    Fleiss, J.L.2    Steinman, R.C.3    Rolnitzky, L.M.4    Schneider, W.J.5    Stein, P.K.6
  • 16
    • 0034692586 scopus 로고    scopus 로고
    • Heart rate recovery and treadmill exercise score as predictors of mortality in patients referred for exercise ECG
    • Nishime E.O., Cole C.R., Blackstone E.H., Pashkow F.J., and Lauer M.S. Heart rate recovery and treadmill exercise score as predictors of mortality in patients referred for exercise ECG. JAMA 284 11 (2000) 1392-1398
    • (2000) JAMA , vol.284 , Issue.11 , pp. 1392-1398
    • Nishime, E.O.1    Cole, C.R.2    Blackstone, E.H.3    Pashkow, F.J.4    Lauer, M.S.5
  • 18
    • 0011910306 scopus 로고
    • Development of a strain of spontaneously hypertensive rats
    • Okamoto K., and Aoki K. Development of a strain of spontaneously hypertensive rats. Jpn. Circ. J. 27 (1963) 282-293
    • (1963) Jpn. Circ. J. , vol.27 , pp. 282-293
    • Okamoto, K.1    Aoki, K.2
  • 19
    • 0018225574 scopus 로고
    • Influence on blood pressure of renal isografts between spontaneously hypertensive and normotensive rats, utilizing the F1 hybrids
    • Kawabe K., Watanabe T.X., Shiono K., and Sokabe H. Influence on blood pressure of renal isografts between spontaneously hypertensive and normotensive rats, utilizing the F1 hybrids. Jpn. Heart J. 19 6 (1978) 886-894
    • (1978) Jpn. Heart J. , vol.19 , Issue.6 , pp. 886-894
    • Kawabe, K.1    Watanabe, T.X.2    Shiono, K.3    Sokabe, H.4
  • 20
    • 0019963499 scopus 로고
    • The sympathetic system in hypertension. State-of-the-art review
    • Abboud F.M. The sympathetic system in hypertension. State-of-the-art review. Hypertension 4 3 Pt 2 (1982) 208-225
    • (1982) Hypertension , vol.4 , Issue.3 PART 2 , pp. 208-225
    • Abboud, F.M.1
  • 21
    • 0033970245 scopus 로고    scopus 로고
    • Altered frequency characteristic of central vasomotor control in SHR
    • Kuo T.B., and Yang C.C. Altered frequency characteristic of central vasomotor control in SHR. Am. J. Physiol. Heart Circ. Physiol. 278 1 (2000) H201-H207
    • (2000) Am. J. Physiol. Heart Circ. Physiol. , vol.278 , Issue.1
    • Kuo, T.B.1    Yang, C.C.2
  • 23
    • 0034111908 scopus 로고    scopus 로고
    • New approach for measurement of sympathetic nervous abnormality in conscious, spontaneously hypertensive rats
    • Tsunoda M., Takezawa K., Santa T., Ina Y., Nagashima K., Ohmori K., et al. New approach for measurement of sympathetic nervous abnormality in conscious, spontaneously hypertensive rats. Jpn. J. Pharmacol. 83 1 (2000) 39-45
    • (2000) Jpn. J. Pharmacol. , vol.83 , Issue.1 , pp. 39-45
    • Tsunoda, M.1    Takezawa, K.2    Santa, T.3    Ina, Y.4    Nagashima, K.5    Ohmori, K.6
  • 24
    • 0019630495 scopus 로고
    • Metabolic responsiveness of spontaneously hypertensive rat to isoproterenol
    • Katovich M.J., Barney C.C., and Fregly M.J. Metabolic responsiveness of spontaneously hypertensive rat to isoproterenol. Am. J. Physiol. 241 4 (1981) H497-504
    • (1981) Am. J. Physiol. , vol.241 , Issue.4
    • Katovich, M.J.1    Barney, C.C.2    Fregly, M.J.3
  • 25
    • 0019796398 scopus 로고
    • Impaired cardiac contractile response to isoproterenol in the spontaneously hypertensive rat
    • Saragoca M., and Tarazi R.C. Impaired cardiac contractile response to isoproterenol in the spontaneously hypertensive rat. Hypertension 3 3 (1981) 380-385
    • (1981) Hypertension , vol.3 , Issue.3 , pp. 380-385
    • Saragoca, M.1    Tarazi, R.C.2
  • 26
    • 33747385372 scopus 로고    scopus 로고
    • Remodeling of the cardiac pacemaker L-type calcium current and its beta-adrenergic responsiveness in hypertension after neuronal NO synthase gene transfer
    • Heaton D.A., Lei M., Li D., Golding S., Dawson T.A., Mohan R.M., et al. Remodeling of the cardiac pacemaker L-type calcium current and its beta-adrenergic responsiveness in hypertension after neuronal NO synthase gene transfer. Hypertension 48 3 (2006) 443-452
    • (2006) Hypertension , vol.48 , Issue.3 , pp. 443-452
    • Heaton, D.A.1    Lei, M.2    Li, D.3    Golding, S.4    Dawson, T.A.5    Mohan, R.M.6
  • 27
    • 0031992663 scopus 로고    scopus 로고
    • Acute exercise and gender alter cardiac autonomic tonus differently in hypertensive and normotensive rats
    • Chandler M.P., and DiCarlo S.E. Acute exercise and gender alter cardiac autonomic tonus differently in hypertensive and normotensive rats. Am. J. Physiol. 274 2 Pt 2 (1998) R510-R516
    • (1998) Am. J. Physiol. , vol.274 , Issue.2 PART 2
    • Chandler, M.P.1    DiCarlo, S.E.2
  • 28
    • 33846428070 scopus 로고    scopus 로고
    • Gene transfer of neuronal nitric oxide synthase into intracardiac ganglia reverses vagal impairment in hypertensive rats
    • Heaton D.A., Li D., Almond S.C., Dawson T.A., Wang L., Channon K.M., et al. Gene transfer of neuronal nitric oxide synthase into intracardiac ganglia reverses vagal impairment in hypertensive rats. Hypertension 49 2 (2007) 380-388
    • (2007) Hypertension , vol.49 , Issue.2 , pp. 380-388
    • Heaton, D.A.1    Li, D.2    Almond, S.C.3    Dawson, T.A.4    Wang, L.5    Channon, K.M.6
  • 29
    • 40649086450 scopus 로고    scopus 로고
    • Neuropeptide Y reduces acetylcholine release and vagal bradycardia via a Y2 receptor-mediated, protein kinase C-dependent pathway
    • Herring N., Lokale M.N., Danson E.J., Heaton D.A., and Paterson D.J. Neuropeptide Y reduces acetylcholine release and vagal bradycardia via a Y2 receptor-mediated, protein kinase C-dependent pathway. J. Mol. Cell. Cardiol. 44 3 (2008) 477-485
    • (2008) J. Mol. Cell. Cardiol. , vol.44 , Issue.3 , pp. 477-485
    • Herring, N.1    Lokale, M.N.2    Danson, E.J.3    Heaton, D.A.4    Paterson, D.J.5
  • 30
    • 0032810811 scopus 로고    scopus 로고
    • Spontaneously hypertensive rats cholinergic hyper-responsiveness: central and peripheral pharmacological mechanisms
    • Lazartigues E., Brefel-Courbon C., Tran M.A., Montastruc J.L., and Rascol O. Spontaneously hypertensive rats cholinergic hyper-responsiveness: central and peripheral pharmacological mechanisms. Br. J. Pharmacol. 127 7 (1999) 1657-1665
    • (1999) Br. J. Pharmacol. , vol.127 , Issue.7 , pp. 1657-1665
    • Lazartigues, E.1    Brefel-Courbon, C.2    Tran, M.A.3    Montastruc, J.L.4    Rascol, O.5
  • 31
    • 0031780086 scopus 로고    scopus 로고
    • Depression of efferent parasympathetic control of heart rate in rats with myocardial infarction: effect of losartan
    • Du X.J., Cox H.S., Dart A.M., and Esler M.D. Depression of efferent parasympathetic control of heart rate in rats with myocardial infarction: effect of losartan. J. Cardiovasc. Pharmacol. 31 6 (1998) 937-944
    • (1998) J. Cardiovasc. Pharmacol. , vol.31 , Issue.6 , pp. 937-944
    • Du, X.J.1    Cox, H.S.2    Dart, A.M.3    Esler, M.D.4
  • 32
    • 85044701512 scopus 로고
    • Evaluation of the vagal efferent pathway in rats in the acute and chronic phases of myocardial infarction
    • Módolo Rda P., Bernardes C.F., Vasquez E.C., and Mill J.G. Evaluation of the vagal efferent pathway in rats in the acute and chronic phases of myocardial infarction. Arq. Bras. Cardiol. 65 1 (1995) 17-22
    • (1995) Arq. Bras. Cardiol. , vol.65 , Issue.1 , pp. 17-22
    • Módolo Rda, P.1    Bernardes, C.F.2    Vasquez, E.C.3    Mill, J.G.4
  • 34
    • 0032568507 scopus 로고    scopus 로고
    • Muscarinic cholinergic regulation of cardiac myocyte ICa-L is absent in mice with targeted disruption of endothelial nitric oxide synthase
    • Han X., Kubota I., Feron O., Opel D.J., Arstall M.A., Zhao Y.Y., et al. Muscarinic cholinergic regulation of cardiac myocyte ICa-L is absent in mice with targeted disruption of endothelial nitric oxide synthase. Proc. Natl. Acad. Sci. U. S. A. 95 11 (1998) 6510-6515
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , Issue.11 , pp. 6510-6515
    • Han, X.1    Kubota, I.2    Feron, O.3    Opel, D.J.4    Arstall, M.A.5    Zhao, Y.Y.6
  • 35
    • 0033017176 scopus 로고    scopus 로고
    • Muscarinic and beta-adrenergic regulation of heart rate, force of contraction and calcium current is preserved in mice lacking endothelial nitric oxide synthase
    • Vandecasteele G., Eschenhagen T., Scholz H., Stein B., Verde I., and Fischmeister R. Muscarinic and beta-adrenergic regulation of heart rate, force of contraction and calcium current is preserved in mice lacking endothelial nitric oxide synthase. Nat. Med. 5 3 (1999) 331-334
    • (1999) Nat. Med. , vol.5 , Issue.3 , pp. 331-334
    • Vandecasteele, G.1    Eschenhagen, T.2    Scholz, H.3    Stein, B.4    Verde, I.5    Fischmeister, R.6
  • 36
    • 0029922195 scopus 로고    scopus 로고
    • Genetic expression of endothelial nitric oxide synthase in human atrial myocardium
    • Wei C., Jiang S., Lust J.A., Daly R.C., and McGregor C.G. Genetic expression of endothelial nitric oxide synthase in human atrial myocardium. Mayo Clin. Proc. 71 4 (1996) 346-350
    • (1996) Mayo Clin. Proc. , vol.71 , Issue.4 , pp. 346-350
    • Wei, C.1    Jiang, S.2    Lust, J.A.3    Daly, R.C.4    McGregor, C.G.5
  • 38
    • 0035449929 scopus 로고    scopus 로고
    • Nitric oxide-cGMP pathway facilitates acetylcholine release and bradycardia during vagal nerve stimulation in the guinea-pig in vitro
    • Herring N., and Paterson D.J. Nitric oxide-cGMP pathway facilitates acetylcholine release and bradycardia during vagal nerve stimulation in the guinea-pig in vitro. J. Physiol. 535 Pt 2 (2001) 507-518
    • (2001) J. Physiol. , vol.535 , Issue.PART 2 , pp. 507-518
    • Herring, N.1    Paterson, D.J.2
  • 39
    • 7544231821 scopus 로고    scopus 로고
    • Cardiomyocyte-restricted overexpression of endothelial nitric oxide synthase (NOS3) attenuates beta-adrenergic stimulation and reinforces vagal inhibition of cardiac contraction
    • Massion P.B., Dessy C., Desjardins F., Pelat M., Havaux X., Belge C., et al. Cardiomyocyte-restricted overexpression of endothelial nitric oxide synthase (NOS3) attenuates beta-adrenergic stimulation and reinforces vagal inhibition of cardiac contraction. Circulation 110 17 (2004) 2666-2672
    • (2004) Circulation , vol.110 , Issue.17 , pp. 2666-2672
    • Massion, P.B.1    Dessy, C.2    Desjardins, F.3    Pelat, M.4    Havaux, X.5    Belge, C.6
  • 40
    • 22744436073 scopus 로고    scopus 로고
    • Disruption of inhibitory G-proteins mediates a reduction in atrial beta-adrenergic signaling by enhancing eNOS expression
    • Danson E.J., Zhang Y.H., Sears C.E., Edwards A.R., Casadei B., and Paterson D.J. Disruption of inhibitory G-proteins mediates a reduction in atrial beta-adrenergic signaling by enhancing eNOS expression. Cardiovasc. Res. 67 4 (2005) 613-623
    • (2005) Cardiovasc. Res. , vol.67 , Issue.4 , pp. 613-623
    • Danson, E.J.1    Zhang, Y.H.2    Sears, C.E.3    Edwards, A.R.4    Casadei, B.5    Paterson, D.J.6
  • 42
    • 33645051704 scopus 로고    scopus 로고
    • Are myocardial eNOS and nNOS involved in the beta-adrenergic and muscarinic regulation of inotropy? A systematic investigation
    • Martin S.R., Emanuel K., Sears C.E., Zhang Y.H., and Casadei B. Are myocardial eNOS and nNOS involved in the beta-adrenergic and muscarinic regulation of inotropy? A systematic investigation. Cardiovasc. Res. 70 1 (2006) 97-106
    • (2006) Cardiovasc. Res. , vol.70 , Issue.1 , pp. 97-106
    • Martin, S.R.1    Emanuel, K.2    Sears, C.E.3    Zhang, Y.H.4    Casadei, B.5
  • 43
    • 0029127216 scopus 로고
    • Endogenous and exogenous nitric oxide inhibits norepinephrine release from rat heart sympathetic nerves
    • Schwarz P., Diem R., Dun N.J., and Förstermann U. Endogenous and exogenous nitric oxide inhibits norepinephrine release from rat heart sympathetic nerves. Circ. Res. 77 4 (1995) 841-848
    • (1995) Circ. Res. , vol.77 , Issue.4 , pp. 841-848
    • Schwarz, P.1    Diem, R.2    Dun, N.J.3    Förstermann, U.4
  • 44
    • 0033566861 scopus 로고    scopus 로고
    • Regulation of cardiac beta adrenergic response by nitric oxide
    • Balligand J.-L. Regulation of cardiac beta adrenergic response by nitric oxide. Cardiovasc Res 43 (1999) 607-620
    • (1999) Cardiovasc Res , vol.43 , pp. 607-620
    • Balligand, J.-L.1
  • 45
    • 41149146649 scopus 로고    scopus 로고
    • Reduced phospholamban phosphorylation is associated with impaired relaxation in left ventricular myocytes from neuronal NO synthase-deficient mice
    • Zhang Y.H., Zhang M.H., Sears C.E., Emanuel K., Redwood C., El-Armouche A., et al. Reduced phospholamban phosphorylation is associated with impaired relaxation in left ventricular myocytes from neuronal NO synthase-deficient mice. Circ. Res. 102 2 (2008) 242-249
    • (2008) Circ. Res. , vol.102 , Issue.2 , pp. 242-249
    • Zhang, Y.H.1    Zhang, M.H.2    Sears, C.E.3    Emanuel, K.4    Redwood, C.5    El-Armouche, A.6
  • 46
    • 0037149489 scopus 로고    scopus 로고
    • Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms
    • Barouch L.A., Harrison R.W., Skaf M.W., Rosas G.O., Cappola T.P., Kobeissi Z.A., et al. Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms. Nature 416 6878 (2002) 337-339
    • (2002) Nature , vol.416 , Issue.6878 , pp. 337-339
    • Barouch, L.A.1    Harrison, R.W.2    Skaf, M.W.3    Rosas, G.O.4    Cappola, T.P.5    Kobeissi, Z.A.6
  • 47
    • 0030898206 scopus 로고    scopus 로고
    • Neuronal nitric oxide reduces sympathetic excitability by modulation of central glutamate effects in pigs
    • Zanzinger J., Czachurski J., and Seller H. Neuronal nitric oxide reduces sympathetic excitability by modulation of central glutamate effects in pigs. Circ. Res. 80 4 (1997) 565-571
    • (1997) Circ. Res. , vol.80 , Issue.4 , pp. 565-571
    • Zanzinger, J.1    Czachurski, J.2    Seller, H.3
  • 48
    • 38349148688 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase-deficient mice have impaired renin release but normal blood pressure
    • Sällström J., Carlström M., Jensen B.L., Skøtt O., Brown R.D., and Persson A.E. Neuronal nitric oxide synthase-deficient mice have impaired renin release but normal blood pressure. Am. J. Hypertens. 21 1 (2008) 111-116
    • (2008) Am. J. Hypertens. , vol.21 , Issue.1 , pp. 111-116
    • Sällström, J.1    Carlström, M.2    Jensen, B.L.3    Skøtt, O.4    Brown, R.D.5    Persson, A.E.6
  • 50
    • 0032190435 scopus 로고    scopus 로고
    • Interaction between neuronal nitric oxide synthase and inhibitory G protein activity in heart rate regulation in conscious mice
    • Jumrussirikul P., Dinerman J., Dawson T.M., Dawson V.L., Ekelund U., Georgakopoulos D., et al. Interaction between neuronal nitric oxide synthase and inhibitory G protein activity in heart rate regulation in conscious mice. J. Clin. Invest. 102 7 (1998) 1279-1285
    • (1998) J. Clin. Invest. , vol.102 , Issue.7 , pp. 1279-1285
    • Jumrussirikul, P.1    Dinerman, J.2    Dawson, T.M.3    Dawson, V.L.4    Ekelund, U.5    Georgakopoulos, D.6
  • 51
    • 33744521410 scopus 로고    scopus 로고
    • Baroreflex responses in neuronal nitric oxide synthase knoukout mice (nNOS)
    • Carvalho T.H., Lopes O.U., and Tolentino-Silva F.R. Baroreflex responses in neuronal nitric oxide synthase knoukout mice (nNOS). Auton. Neurosci. 126-127 (2006) 163-168
    • (2006) Auton. Neurosci. , vol.126-127 , pp. 163-168
    • Carvalho, T.H.1    Lopes, O.U.2    Tolentino-Silva, F.R.3
  • 52
    • 18044372661 scopus 로고    scopus 로고
    • Exercise training improves endogenous nitric oxide mechanisms within the paraventricular nucleus in rats with heart failure
    • Zheng H., Li Y.F., Cornish K.G., Zucker I.H., and Patel K.P. Exercise training improves endogenous nitric oxide mechanisms within the paraventricular nucleus in rats with heart failure. Am. J. Physiol. Heart Circ. Physiol. 288 5 (2005) H2332-H2341
    • (2005) Am. J. Physiol. Heart Circ. Physiol. , vol.288 , Issue.5
    • Zheng, H.1    Li, Y.F.2    Cornish, K.G.3    Zucker, I.H.4    Patel, K.P.5
  • 54
    • 11144250181 scopus 로고    scopus 로고
    • Effects of nNOS antisense in the paraventricular nucleus on blood pressure and heart rate in rats with heart failure
    • Wang Y., Liu X.F., Cornish K.G., Zucker I.H., and Patel K.P. Effects of nNOS antisense in the paraventricular nucleus on blood pressure and heart rate in rats with heart failure. Am. J. Physiol. Heart Circ. Physiol. 288 1 (2005) H205-H213
    • (2005) Am. J. Physiol. Heart Circ. Physiol. , vol.288 , Issue.1
    • Wang, Y.1    Liu, X.F.2    Cornish, K.G.3    Zucker, I.H.4    Patel, K.P.5
  • 55
    • 0035281015 scopus 로고    scopus 로고
    • Adenoviral vector demonstrates that angiotensin II-induced depression of the cardiac baroreflex is mediated by endothelial nitric oxide synthase in the nucleus tractus solitarii of the rat
    • Paton J.F., Deuchars J., Ahmad Z., Wong L.F., Murphy D., and Kasparov S. Adenoviral vector demonstrates that angiotensin II-induced depression of the cardiac baroreflex is mediated by endothelial nitric oxide synthase in the nucleus tractus solitarii of the rat. J. Physiol. 531 Pt 2 (2001) 445-458
    • (2001) J. Physiol. , vol.531 , Issue.PART 2 , pp. 445-458
    • Paton, J.F.1    Deuchars, J.2    Ahmad, Z.3    Wong, L.F.4    Murphy, D.5    Kasparov, S.6
  • 56
    • 0033664393 scopus 로고    scopus 로고
    • Overexpression of eNOS in NTS causes hypotension and bradycardia in vivo
    • Sakai K., Hirooka Y., Matsuo I., Eshima K., Shigematsu H., Shimokawa H., et al. Overexpression of eNOS in NTS causes hypotension and bradycardia in vivo. Hypertension 36 6 (2000) 1023-1028
    • (2000) Hypertension , vol.36 , Issue.6 , pp. 1023-1028
    • Sakai, K.1    Hirooka, Y.2    Matsuo, I.3    Eshima, K.4    Shigematsu, H.5    Shimokawa, H.6
  • 57
    • 34250830359 scopus 로고    scopus 로고
    • Noradrenergic cell specific gene transfer with neuronal nitric oxide synthase reduces cardiac sympathetic neurotransmission in hypertensive rats
    • Li D., Wang L., Lee C.W., Dawson T.A., and Paterson D.J. Noradrenergic cell specific gene transfer with neuronal nitric oxide synthase reduces cardiac sympathetic neurotransmission in hypertensive rats. Hypertension 50 1 (2007) 69-74
    • (2007) Hypertension , vol.50 , Issue.1 , pp. 69-74
    • Li, D.1    Wang, L.2    Lee, C.W.3    Dawson, T.A.4    Paterson, D.J.5
  • 58
    • 0033969334 scopus 로고    scopus 로고
    • Chronic oxidative stress in the RVLM modulates sympathetic control of circulation in pigs
    • Zanzinger J., and Czachurski J. Chronic oxidative stress in the RVLM modulates sympathetic control of circulation in pigs. Pflugers Arch. 439 4 (2000) 489-494
    • (2000) Pflugers Arch. , vol.439 , Issue.4 , pp. 489-494
    • Zanzinger, J.1    Czachurski, J.2
  • 59
    • 2442706556 scopus 로고    scopus 로고
    • Increased reactive oxygen species in rostral ventrolateral medulla contribute to neural mechanisms of hypertension in stroke-prone spontaneously hypertensive rats
    • Kishi T., Hirooka Y., Kimura Y., Ito K., Shimokawa H., and Takeshita A. Increased reactive oxygen species in rostral ventrolateral medulla contribute to neural mechanisms of hypertension in stroke-prone spontaneously hypertensive rats. Circulation 109 19 (2004) 2357-2362
    • (2004) Circulation , vol.109 , Issue.19 , pp. 2357-2362
    • Kishi, T.1    Hirooka, Y.2    Kimura, Y.3    Ito, K.4    Shimokawa, H.5    Takeshita, A.6
  • 61
    • 0034965841 scopus 로고    scopus 로고
    • Oxygen radical-mediated reduction in basal and agonist-evoked NO release in isolated rat heart
    • Paolocci N., Biondi R., Bettini M., Lee C.I., Berlowitz C.O., Rossi R., et al. Oxygen radical-mediated reduction in basal and agonist-evoked NO release in isolated rat heart. J. Mol. Cell. Cardiol. 33 4 (2001 Apr) 671-679
    • (2001) J. Mol. Cell. Cardiol. , vol.33 , Issue.4 , pp. 671-679
    • Paolocci, N.1    Biondi, R.2    Bettini, M.3    Lee, C.I.4    Berlowitz, C.O.5    Rossi, R.6
  • 62
    • 0033711226 scopus 로고    scopus 로고
    • Angiotensin II acutely attenuates range of arterial baroreflex control of renal sympathetic nerve activity
    • Sanderford M.G., and Bishop V.S. Angiotensin II acutely attenuates range of arterial baroreflex control of renal sympathetic nerve activity. Am. J. Physiol. Heart Circ. Physiol. 279 4 (2000) H1804-H1812
    • (2000) Am. J. Physiol. Heart Circ. Physiol. , vol.279 , Issue.4
    • Sanderford, M.G.1    Bishop, V.S.2
  • 63
    • 0034743302 scopus 로고    scopus 로고
    • Effect of the AT1-receptor antagonists losartan, irbesartan, and telmisartan on angiotensin II-induced facilitation of sympathetic neurotransmission in the rat mesenteric artery
    • Balt J.C., Mathy M.J., Nap A., Pfaffendorf M., and van Zwieten P.A. Effect of the AT1-receptor antagonists losartan, irbesartan, and telmisartan on angiotensin II-induced facilitation of sympathetic neurotransmission in the rat mesenteric artery. J. Cardiovasc. Pharmacol. 38 1 (2001) 141-148
    • (2001) J. Cardiovasc. Pharmacol. , vol.38 , Issue.1 , pp. 141-148
    • Balt, J.C.1    Mathy, M.J.2    Nap, A.3    Pfaffendorf, M.4    van Zwieten, P.A.5
  • 64
    • 0037155772 scopus 로고    scopus 로고
    • Brain-selective overexpression of angiotensin (AT1) receptors causes enhanced cardiovascular sensitivity in transgenic mice
    • Lazartigues E., Dunlay S.M., Loihl A.K., Sinnayah P., Lang J.A., Espelund J.J., et al. Brain-selective overexpression of angiotensin (AT1) receptors causes enhanced cardiovascular sensitivity in transgenic mice. Circ. Res. 90 5 (2002) 617-624
    • (2002) Circ. Res. , vol.90 , Issue.5 , pp. 617-624
    • Lazartigues, E.1    Dunlay, S.M.2    Loihl, A.K.3    Sinnayah, P.4    Lang, J.A.5    Espelund, J.J.6
  • 65
    • 0028365310 scopus 로고
    • Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells
    • Griendling K.K., Minieri C.A., Ollerenshaw J.D., and Alexander R.W. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ. Res. 74 6 (1994) 1141-1148
    • (1994) Circ. Res. , vol.74 , Issue.6 , pp. 1141-1148
    • Griendling, K.K.1    Minieri, C.A.2    Ollerenshaw, J.D.3    Alexander, R.W.4
  • 66
    • 0037195696 scopus 로고    scopus 로고
    • Superoxide mediates the actions of angiotensin II in the central nervous system
    • Zimmerman M.C., Lazartigues E., Lang J.A., Sinnayah P., Ahmad I.M., Spitz D.R., et al. Superoxide mediates the actions of angiotensin II in the central nervous system. Circ. Res. 91 11 (2002) 1038-1045
    • (2002) Circ. Res. , vol.91 , Issue.11 , pp. 1038-1045
    • Zimmerman, M.C.1    Lazartigues, E.2    Lang, J.A.3    Sinnayah, P.4    Ahmad, I.M.5    Spitz, D.R.6
  • 67
    • 33847047460 scopus 로고    scopus 로고
    • Exercise training prevents arterial baroreflex dysfunction in rats treated with central angiotensin II
    • Pan Y.X., Gao L., Wang W.Z., Zheng H., Liu D., Patel K.P., et al. Exercise training prevents arterial baroreflex dysfunction in rats treated with central angiotensin II. Hypertension 49 3 (2007) 519-527
    • (2007) Hypertension , vol.49 , Issue.3 , pp. 519-527
    • Pan, Y.X.1    Gao, L.2    Wang, W.Z.3    Zheng, H.4    Liu, D.5    Patel, K.P.6
  • 68
    • 38549179821 scopus 로고    scopus 로고
    • Effects of angiotensin type 2 receptor overexpression in the rostral ventrolateral medulla on blood pressure and urine excretion in normal rats
    • Gao L., Wang W., Wang W., Li H., Sumners C., and Zucker I.H. Effects of angiotensin type 2 receptor overexpression in the rostral ventrolateral medulla on blood pressure and urine excretion in normal rats. Hypertension 51 2 (2008) 521-527
    • (2008) Hypertension , vol.51 , Issue.2 , pp. 521-527
    • Gao, L.1    Wang, W.2    Wang, W.3    Li, H.4    Sumners, C.5    Zucker, I.H.6
  • 69
    • 2542478969 scopus 로고    scopus 로고
    • Ascorbic acid increases cardiovagal baroreflex sensitivity in healthy older men
    • Monahan K.D., Eskurza I., and Seals D.R. Ascorbic acid increases cardiovagal baroreflex sensitivity in healthy older men. Am. J. Physiol. Heart Circ. Physiol. 286 6 (2004) H2113-H2117
    • (2004) Am. J. Physiol. Heart Circ. Physiol. , vol.286 , Issue.6
    • Monahan, K.D.1    Eskurza, I.2    Seals, D.R.3
  • 70
    • 0031028636 scopus 로고    scopus 로고
    • Effects of treatment with the antioxidant alpha-lipoic acid on cardiac autonomic neuropathy in NIDDM patients. A 4-month randomized controlled multicenter trial (DEKAN Study). Deutsche Kardiale Autonome Neuropathie
    • Ziegler D., Schatz H., Conrad F., Gries F.A., Ulrich H., and Reichel G. Effects of treatment with the antioxidant alpha-lipoic acid on cardiac autonomic neuropathy in NIDDM patients. A 4-month randomized controlled multicenter trial (DEKAN Study). Deutsche Kardiale Autonome Neuropathie. Diabetes Care 20 3 (1997) 369-373
    • (1997) Diabetes Care , vol.20 , Issue.3 , pp. 369-373
    • Ziegler, D.1    Schatz, H.2    Conrad, F.3    Gries, F.A.4    Ulrich, H.5    Reichel, G.6
  • 71
    • 0037332063 scopus 로고    scopus 로고
    • Atorvastatin causes depressor and sympatho-inhibitory effects with upregulation of nitric oxide synthases in stroke-prone spontaneously hypertensive rats
    • Kishi T., Hirooka Y., Mukai Y., Shimokawa H., and Takeshita A. Atorvastatin causes depressor and sympatho-inhibitory effects with upregulation of nitric oxide synthases in stroke-prone spontaneously hypertensive rats. J. Hypertens. 21 2 (2003) 379-386
    • (2003) J. Hypertens. , vol.21 , Issue.2 , pp. 379-386
    • Kishi, T.1    Hirooka, Y.2    Mukai, Y.3    Shimokawa, H.4    Takeshita, A.5
  • 72
    • 20644441566 scopus 로고    scopus 로고
    • Targeted nNOS gene transfer into the cardiac vagus rapidly increases parasympathetic function in the pig
    • Heaton D.A., Golding S., Bradley C.P., Dawson T.A., Cai S., Channon K.M., et al. Targeted nNOS gene transfer into the cardiac vagus rapidly increases parasympathetic function in the pig. J. Mol. Cell. Cardiol. 39 1 (2005) 159-164
    • (2005) J. Mol. Cell. Cardiol. , vol.39 , Issue.1 , pp. 159-164
    • Heaton, D.A.1    Golding, S.2    Bradley, C.P.3    Dawson, T.A.4    Cai, S.5    Channon, K.M.6
  • 74
    • 0034808550 scopus 로고    scopus 로고
    • A high-efficiency synthetic promoter that drives transgene expression selectively in noradrenergic neurons
    • Hwang D.Y., Carlezon Jr. W.A., Isacson O., and Kim K.S. A high-efficiency synthetic promoter that drives transgene expression selectively in noradrenergic neurons. Hum. Gene Ther. 12 14 (2001) 1731-1740
    • (2001) Hum. Gene Ther. , vol.12 , Issue.14 , pp. 1731-1740
    • Hwang, D.Y.1    Carlezon Jr., W.A.2    Isacson, O.3    Kim, K.S.4
  • 75
    • 33746099695 scopus 로고    scopus 로고
    • Noradrenergic neuron-specific overexpression of nNOS in cardiac sympathetic nerves decreases neurotransmission
    • Wang L., Li D., Plested C.P., Dawson T., Teschemacher A.G., and Paterson D.J. Noradrenergic neuron-specific overexpression of nNOS in cardiac sympathetic nerves decreases neurotransmission. J. Mol. Cell. Cardiol. 41 2 (2006) 364-370
    • (2006) J. Mol. Cell. Cardiol. , vol.41 , Issue.2 , pp. 364-370
    • Wang, L.1    Li, D.2    Plested, C.P.3    Dawson, T.4    Teschemacher, A.G.5    Paterson, D.J.6
  • 76
    • 34250830359 scopus 로고    scopus 로고
    • Noradrenergic cell specific gene transfer with neuronal nitric oxide synthase reduces cardiac sympathetic neurotransmission in hypertensive rats
    • Li D., Wang L., Lee C.W., Dawson T.A., and Paterson D.J. Noradrenergic cell specific gene transfer with neuronal nitric oxide synthase reduces cardiac sympathetic neurotransmission in hypertensive rats. Hypertension 50 1 (2007) 69-74
    • (2007) Hypertension , vol.50 , Issue.1 , pp. 69-74
    • Li, D.1    Wang, L.2    Lee, C.W.3    Dawson, T.A.4    Paterson, D.J.5
  • 77
    • 36448990091 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase gene transfer decreases [Ca2+]i in cardiac sympathetic neurons
    • Wang L., Henrich M., Buckler K.J., McMenamin M., Mee C.J., Sattelle D.B., et al. Neuronal nitric oxide synthase gene transfer decreases [Ca2+]i in cardiac sympathetic neurons. J. Mol. Cell. Cardiol. 43 6 (2007) 717-725
    • (2007) J. Mol. Cell. Cardiol. , vol.43 , Issue.6 , pp. 717-725
    • Wang, L.1    Henrich, M.2    Buckler, K.J.3    McMenamin, M.4    Mee, C.J.5    Sattelle, D.B.6
  • 78
    • 27644537902 scopus 로고    scopus 로고
    • Stoichiometric relationships between endothelial tetrahydrobiopterin, endothelial NO synthase (eNOS) activity, and eNOS coupling in vivo: insights from transgenic mice with endothelial-targeted GTP cyclohydrolase 1 and eNOS overexpression
    • Bendall J.K., Alp N.J., Warrick N., Cai S., Adlam D., Rockett K., et al. Stoichiometric relationships between endothelial tetrahydrobiopterin, endothelial NO synthase (eNOS) activity, and eNOS coupling in vivo: insights from transgenic mice with endothelial-targeted GTP cyclohydrolase 1 and eNOS overexpression. Circ. Res. 97 9 (2005) 864-871
    • (2005) Circ. Res. , vol.97 , Issue.9 , pp. 864-871
    • Bendall, J.K.1    Alp, N.J.2    Warrick, N.3    Cai, S.4    Adlam, D.5    Rockett, K.6


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