Remodeling of the cardiac pacemaker L-type calcium current and its β-adrenergic responsiveness in hypertension after neuronal NO synthase gene transfer

Hypertension

Volumn 48, Issue 3, 2006, Pages 443-452

  Heaton, Daniel A ^a   Lei, Ming ^a   Li, Dan ^a   Golding, Simon ^a   Dawson, Tom A ^a   Mohan, Ravi M ^a   Paterson, David J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Nitric oxide synthase; Norepinephrine; Sinoatrial node

Indexed keywords

ADENOVIRUS VECTOR; CALCIUM CHANNEL L TYPE; CYCLIC AMP; CYCLIC GMP; CYCLIC NUCLEOTIDE; ENHANCED GREEN FLUORESCENT PROTEIN; NEUROHORMONE; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NORADRENALIN;

ADRENERGIC SYSTEM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL HEART PACEMAKER; CALCIUM CURRENT; CELL ISOLATION; CHRONOTROPISM; CONTROLLED STUDY; GENE EXPRESSION; GENE TRANSFER; GENETIC TRANSFECTION; HEART ATRIUM PACEMAKER; HYPERTENSION; MALE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SINUS NODE; SPONTANEOUSLY HYPERTENSIVE RAT; TISSUE SECTION; TRANSGENE;

ADRENERGIC ALPHA-AGONISTS; ANIMALS; CALCIUM CHANNELS, L-TYPE; CYCLIC AMP; CYCLIC GMP; GENE TRANSFER TECHNIQUES; HEART ATRIA; HEART RATE; HYPERTENSION; MALE; MYOCARDIUM; NITRIC OXIDE SYNTHASE TYPE I; NOREPINEPHRINE; NUCLEOTIDES, CYCLIC; PHENOTYPE; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RECEPTORS, ADRENERGIC, BETA; SIGNAL TRANSDUCTION; SINOATRIAL NODE;

EID: 33747385372     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.0000233383.04280.3c     Document Type: Article

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