Neuronal nitric oxide reduces sympathetic excitability by modulation of central glutamate effects in pigs

Circulation Research

Volumn 80, Issue 4, 1997, Pages 565-571

  Zanzinger, Johannes ^a   Czachurski, Jürgen ^b   Seller, Horst ^b  

^a Physiologisches Institut   (Germany)

^b NONE

Author keywords

7 nitroindazole; nitric oxide; nitro L arginine; S nitroso N acetyl penicillamine; sympathetic activity

Indexed keywords

7 NITROINDAZOLE; ARGININE; GLUTAMIC ACID; N ACETYL S NITROSOPENICILLAMINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR;

ANIMAL EXPERIMENT; ARTERIAL BLOOD; ARTICLE; CONTROLLED STUDY; DENERVATION; HEART OUTPUT; NONHUMAN; PRIORITY JOURNAL; SCIATIC NERVE; SWINE; SYMPATHETIC NERVE; SYMPATHETIC TONE;

EID: 0030898206     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.80.4.565     Document Type: Article

References (37)

1. Shapoval LN, Sagach VF, Pobegailo LS. Nitric oxide influences ventrolateral medullary mechanisms of vasomotor control in the cat. Neurosci Lett. 1991;132:47-50.
2. Zanzinger J, Czachurski J, Seller H. Inhibition of basal and reflex-mediated sympathetic activity in the RVLM by nitric oxide. Am J Physiol. 1995;268:R958-R962.
3. Dampney RAL. Functional organization of central pathways regulating the cardiovascular system. Physiol Rev. 1994;74:323-364.
4. Ma S, Abboud FM, Felder RB. Effects of L-arginine-derived nitric oxide synthesis on neuronal activity in nucleus tractus solitarius. Am J Physiol. 1995;268:R487-R491.
5. Ogawa H, Mizusawa A, Kikuchi Y, Hida W, Miki H, Shirato K. Nitric oxide as a retrograde messenger in the nucleus tractus solitarii of rats during hypoxia. J Physiol (Lond). 1995;486:495-504.
6. Schmid HA, Pehl U. Regional specific effects of nitric oxide donors and cGMP on the electrical activity of neurons in the rat spinal cord. J Chem Neuroanat. 1996;10:197-201.
7. Hakim MA, Hirooka Y, Coleman MJ, Bennett MR, Dampney RAL. Evidence for a critical role of nitric oxide in the tonic excitation of rabbit renal sympathetic preganglionic neurones. J Physiol (Lond). 1995;482:401-407.
8. Hirai T, Musch TI, Morgan DA, Kregel KC, Claassen DE, Pickar JG, Lewis SJ, Kenney MJ. Differential sympathetic nerve responses to nitric oxide synthase inhibition in anesthetized rats. Am J Physiol. 1995;269:R807-R813.
9. Liu JL, Murakami H, Zucker IH. Effects of NO on baroreflex control of heart rate and renal nerve activity in conscious rabbits. Am J Physiol. 1996;39:R1361-R1370.
10. Hansen J, Jacobsen TN, Victor RG. Is nitric oxide involved in the tonic inhibition of central sympathetic outflow in humans? Hypertension. 1994;24:439-444.
11. Mayer B, Klatt P, Werner ER, Schmidt K. Molecular mechanisms of inhibition of porcine brain nitric oxide synthase by the antinociceptive drug 7-nitro-indazole. Neuropharmacology. 1994;33:1253-1259.
12. Furfine ES, Harmon MF, Paith JE, Knowles RG, Salter M, Kiff RJ, Duffy C, Hazelwood R, Oplinger JA, Garvey EP. Potent and selective inhibition of human nitric oxide synthases: selective inhibition of neuronal nitric oxide synthase by S-methyl-L-thiocitrulline and S-ethyl-L-thiocitrulline. J Biol Chem. 1994;269:26677-26683.
13. Lipton SA, Choi YB, Pan ZH, Lei SZ, Chen HSV, Sucher NJ, Loscalzo J, Singel DJ, Stamler JS. A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds. Nature. 1993;364:626-632.
14. Jia L, Bonaventura C, Bonaventura J, Stamler JS. S-Nitrosohemoglobin: a dynamic activity of blood involved in vascular control. Nature. 1996;380:221-226.
15. Jimbo M, Suzuki H, Ichikawa M, Kumagai K, Nishizawa M, Saruta T. Role of nitric oxide in regulation of baroreceptor reflex. J Auton Nerv Syst. 1994;50:209-219.
16. Zanzinger J, Czachurski J, Seller H. Effects of nitric oxide on sympathetic baroreflex transmission in the nucleus tractus solitarii and caudal ventrolateral medulla in cats. Neurosci Lett. 1995;197:199-202.
17. Spyer KM. Central nervous mechanisms contributing to cardiovascular control. J Physiol (Lond). 1994;474:1-19.
18. Gordon FJ. Aortic baroreceptor reflexes are mediated by NMDA receptors in caudal ventrolateral medulla. Am J Physiol. 1987;252:R628-R633.
19. Gordon FJ. Excitatory amino acid receptors in central cardiovascular regulation. Clin Exp Hypertens. 1995;17:81-90.
20. Cravo SL, Morrison SF. The caudal ventrolateral medulla is a source of tonic sympathoinhibition. Brain Res. 1993;621:133-136.
21. Zanzinger J, Doutheil J, Czachurski J, Seller H. Excitatory somato-sympathetic reflexes are relayed in the caudal ventrolateral medulla in the cat. Neurosci Lett. 1994;179:71-74.
22. Zanzinger J, Czachurski J, Offner B, Seller H. Somato-sympathetic reflex transmission in the ventrolateral medulla oblongata: spatial organization and receptor types. Brain Res. 1994;656:353-358.
23. Nagata O, Li WM, Sato A. Glutamate N methyl D aspartate (NMDA) and non NMDA receptor antagonists administered into the brain stem depress the renal sympathetic reflex discharges evoked by single shock of somatic afferents in anesthetized rats. Neurosci Lett. 1995;201:111-114.
24. G-Methyl-L-arginine, an inhibitor of L-arginine-derived nitric oxide synthesis, stimulates renal sympathetic nerve activity in vivo: a role for nitric oxide in the central regulation of sympathetic tone? Circ Res. 1992;70:607-611.
25. Harada S, Tokunaga S, Momohara M, Masaki H, Tagawa T, Imaizumi T, Takeshita A. Inhibition of nitric oxide formation in the nucleus tractus solitarius increases renal sympathetic nerve activity in rabbits. Circ Res. 1993;72:511-516.
26. Matsuoka H, Nishida H, Nomura G, Van Vliet BN, Toshima H. Hypertension induced by nitric oxide synthesis inhibition is renal nerve dependent. Hypertension. 1994;23:971-975.
27. G-nitro-L-arginine methyl ester treatment in conscious rats. Hypertension. 1994;23:982-986.
28. Gopalakrishna R, Chen ZH, Gundimeda U. Nitric oxide and nitric oxide-generating agents induce a reversible inactivation of protein kinase C activity and phorbol ester binding. J Biol Chem. 1993;268:27180-27185.
29. Garthwaite J, Boulton CL. Nitric oxide signaling in the central nervous system. Annu Rev Physiol. 1995;57:683-706.
30. Zhang J, Snyder SH. Nitric oxide in the nervous system. Annu Rev Pharmacol Toxicol. 1995;35:213-233.
31. Huang PL, Huang ZH, Mashimo H, Bloch KD, Moskowitz MA, Bevan JA, Fishman MC. Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature. 1995;377:239-242.
32. Irikura K, Huang PL, Ma J, Lee WS, Dalkara T, Fishman MC, Dawson TM, Snyder SH, Moskowitz MA. Cerebrovascular alterations in mice lacking neuronal nitric oxide synthase gene expression. Proc Natl Acad Sci U S A. 1995;92:6823-6827.
33. Babbedge RC, Bland-Ward PA, Hart SL, Moore PK. Inhibition of rat cerebellar nitric oxide synthase by 7-nitro indazole and related substituted indazoles. Br J Pharmacol. 1993;110:225-228.
34. MacKenzie GM, Rose S, Bland-Ward PA, Moore PK, Jenner P, Marsden CD. Time course of inhibition of brain nitric oxide synthase by 7-nitro indazole. Neuroreport. 1994;5:1993-1996.
35. Wang Q, Pelligrino DA, Baughman VL, Koenig HM, Albrecht RF. The role of neuronal nitric oxide synthase in regulation of cerebral blood flow in normocapnia and hypercapnia in rats. J Cereb Blood Flow Metab. 1995;15:774-778.
36. Bland-Ward PA, Moore PK. 7-Nitro indazole derivatives are potent inhibitors of brain, endothelium and inducible isoforms of nitric oxide synthase. Life Sci. 1995;57:PL131-PL135.
37. Zagvazdin Y, Sancesario G, Wang YX, Share L, Fitzgerald ME, Reiner A. Evidence from its cardiovascular effects that 7 nitro-indazole may inhibit endothelial nitric oxide synthase in vivo. Eur J Pharmacol. 1996;303;61-69.