-
1
-
-
48949118733
-
HIV-1 Vif, APOBEC, and intrinsic immunity
-
Goila-Gaur R, Strebel K: HIV-1 Vif, APOBEC, and intrinsic immunity. Retrovirology 2008, 5:51.
-
(2008)
Retrovirology
, vol.5
, pp. 51
-
-
Goila-Gaur, R.1
Strebel, K.2
-
2
-
-
33646825049
-
APOBEC3 cytidine deaminases: Distinct antiviral actions along the retroviral life cycle
-
Chiu YL, Greene WC: APOBEC3 cytidine deaminases: distinct antiviral actions along the retroviral life cycle. J Biol Chem 2006, 281:8309-8312.
-
(2006)
J Biol Chem
, vol.281
, pp. 8309-8312
-
-
Chiu, Y.L.1
Greene, W.C.2
-
3
-
-
0037043699
-
Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein
-
Sheehy AM, Gaddis NC, Choi JD, et al.: Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein. Nature 2002, 418:646-650.
-
(2002)
Nature
, vol.418
, pp. 646-650
-
-
Sheehy, A.M.1
Gaddis, N.C.2
Choi, J.D.3
-
4
-
-
0036200070
-
An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22
-
Jarmuz A, Chester A, Bayliss J, et al.: An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22. Genomics 2002, 79:285-296.
-
(2002)
Genomics
, vol.79
, pp. 285-296
-
-
Jarmuz, A.1
Chester, A.2
Bayliss, J.3
-
5
-
-
0027200620
-
Molecular cloning of an apolipoprotein B messenger RNA editing protein
-
Teng B, Burant CF, Davidson NO: Molecular cloning of an apolipoprotein B messenger RNA editing protein. Science 1993, 260:1816-1819.
-
(1993)
Science
, vol.260
, pp. 1816-1819
-
-
Teng, B.1
Burant, C.F.2
Davidson, N.O.3
-
6
-
-
2342633240
-
Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome
-
Yu Q, Konig R, Pillai S, et al.: Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome. Nat Struct Mol Biol 2004, 11:435-442.
-
(2004)
Nat Struct Mol Biol
, vol.11
, pp. 435-442
-
-
Yu, Q.1
Konig, R.2
Pillai, S.3
-
7
-
-
33745067722
-
-
• Chelico L, Pham P, Calabrese P, et al.: APOBEC3G DNA deaminase acts processively 3′ → 5′ on single-stranded DNA. Nat Struct Mol Biol 2006, 13:392-399. The study used oligonucleotide substrates to show how APOBEC3G slides and jumps on single-stranded DNA.
-
• Chelico L, Pham P, Calabrese P, et al.: APOBEC3G DNA deaminase acts processively 3′ → 5′ on single-stranded DNA. Nat Struct Mol Biol 2006, 13:392-399. The study used oligonucleotide substrates to show how APOBEC3G slides and jumps on single-stranded DNA.
-
-
-
-
8
-
-
33947732622
-
Stoichiometry of the antiviral protein APOBEC3G in HIV-1 virions
-
Xu H, Chertova E, Chen J, et al.: Stoichiometry of the antiviral protein APOBEC3G in HIV-1 virions. Virology 2007, 360:247-256.
-
(2007)
Virology
, vol.360
, pp. 247-256
-
-
Xu, H.1
Chertova, E.2
Chen, J.3
-
9
-
-
0242578406
-
Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex
-
Yu X, Yu Y, Liu B, et al.: Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex. Science 2003, 302:1056-1060.
-
(2003)
Science
, vol.302
, pp. 1056-1060
-
-
Yu, X.1
Yu, Y.2
Liu, B.3
-
10
-
-
1542379821
-
Vif overcomes the innate antiviral activity of APOBEC3G by promoting its degradation in the ubiquitin-proteasome pathway
-
Mehle A, Strack B, Ancuta P, et al.: Vif overcomes the innate antiviral activity of APOBEC3G by promoting its degradation in the ubiquitin-proteasome pathway. J Biol Chem 2004, 279:7792-7798.
-
(2004)
J Biol Chem
, vol.279
, pp. 7792-7798
-
-
Mehle, A.1
Strack, B.2
Ancuta, P.3
-
11
-
-
10044228286
-
Selective assembly of HIV-1 Vif-Cul5-ElonginB-ElonginC E3 ubiquitin ligase complex through a novel SOCS box and upstream cysteines
-
Yu Y, Xiao Z, Ehrlich ES, et al.: Selective assembly of HIV-1 Vif-Cul5-ElonginB-ElonginC E3 ubiquitin ligase complex through a novel SOCS box and upstream cysteines. Genes Dev 2004, 18:2867-2872.
-
(2004)
Genes Dev
, vol.18
, pp. 2867-2872
-
-
Yu, Y.1
Xiao, Z.2
Ehrlich, E.S.3
-
12
-
-
15744390742
-
The retroviral hypermutation specificity of APOBEC3F and APOBEC3G is governed by the C-terminal DNA cytosine deaminase domain
-
Hache G, Liddament MT, Harris RS: The retroviral hypermutation specificity of APOBEC3F and APOBEC3G is governed by the C-terminal DNA cytosine deaminase domain. J Biol Chem 2005, 280:10920-10924.
-
(2005)
J Biol Chem
, vol.280
, pp. 10920-10924
-
-
Hache, G.1
Liddament, M.T.2
Harris, R.S.3
-
13
-
-
13844270834
-
Complementary function of the two catalytic domains of APOBEC3G
-
Navarro F, Bollman B, Chen H, et al.: Complementary function of the two catalytic domains of APOBEC3G. Virology 2005, 333:374-386.
-
(2005)
Virology
, vol.333
, pp. 374-386
-
-
Navarro, F.1
Bollman, B.2
Chen, H.3
-
14
-
-
5344222683
-
Specific packaging of APOBEC3G into HIV-1 virions is mediated by the nucleocapsid domain of the gag polyprotein precursor
-
Schafer A, Bogerd HP, Cullen BR: Specific packaging of APOBEC3G into HIV-1 virions is mediated by the nucleocapsid domain of the gag polyprotein precursor. Virology 2004, 328:163-168.
-
(2004)
Virology
, vol.328
, pp. 163-168
-
-
Schafer, A.1
Bogerd, H.P.2
Cullen, B.R.3
-
15
-
-
51149120614
-
APOBEC3 encodes Rfv3, a gene influencing neutralizing antibody control of retrovirus infection
-
Santiago ML, Montano M, Benitez R, et al.: APOBEC3 encodes Rfv3, a gene influencing neutralizing antibody control of retrovirus infection. Science 2008, 321:1343-1346.
-
(2008)
Science
, vol.321
, pp. 1343-1346
-
-
Santiago, M.L.1
Montano, M.2
Benitez, R.3
-
16
-
-
33847200788
-
APOBEC3 inhibits mouse mammary tumour virus replication in vivo
-
Okeoma CM, Lovsin N, Peterlin BM, et al.: APOBEC3 inhibits mouse mammary tumour virus replication in vivo. Nature 2007, 445:927-930.
-
(2007)
Nature
, vol.445
, pp. 927-930
-
-
Okeoma, C.M.1
Lovsin, N.2
Peterlin, B.M.3
-
17
-
-
1542513556
-
Mobile elements: Drivers of genome evolution
-
Kazazian HH Jr: Mobile elements: drivers of genome evolution. Science 2004, 303:1626-1632.
-
(2004)
Science
, vol.303
, pp. 1626-1632
-
-
Kazazian Jr, H.H.1
-
18
-
-
31644442239
-
APOBEC3A and APOBEC3B are potent inhibitors of LTR-retrotransposon function in human cells
-
Bogerd HP, Wiegand HL, Doehle BP, et al.: APOBEC3A and APOBEC3B are potent inhibitors of LTR-retrotransposon function in human cells. Nucleic Acids Res 2006, 34:89-95.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 89-95
-
-
Bogerd, H.P.1
Wiegand, H.L.2
Doehle, B.P.3
-
19
-
-
33644769083
-
-
• Chen H, Lilley CE, Yu Q, et al.: APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons. Curr Biol 2006, 16:480-485. The study shows that APOBEC3A does not restrict retroviruses but is a potent inhibitor of adeno-associated virus and murine retrotransposons.
-
• Chen H, Lilley CE, Yu Q, et al.: APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons. Curr Biol 2006, 16:480-485. The study shows that APOBEC3A does not restrict retroviruses but is a potent inhibitor of adeno-associated virus and murine retrotransposons.
-
-
-
-
20
-
-
13444282074
-
APOBEC3G cytidine deaminase inhibits retrotransposition of endogenous retroviruses
-
Esnault C, Heidmann O, Delebecque F, et al.: APOBEC3G cytidine deaminase inhibits retrotransposition of endogenous retroviruses. Nature 2005, 433:430-433.
-
(2005)
Nature
, vol.433
, pp. 430-433
-
-
Esnault, C.1
Heidmann, O.2
Delebecque, F.3
-
21
-
-
19344362934
-
Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G
-
Sawyer SL, Emerman M, Malik HS: Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G. PLoS Biol 2004, 2:E275.
-
(2004)
PLoS Biol
, vol.2
-
-
Sawyer, S.L.1
Emerman, M.2
Malik, H.S.3
-
22
-
-
0026739866
-
Evolution of the primate lentiviruses: Evidence from Vpx and Vpr
-
Tristem M, Marshall C, Karpas A, et al.: Evolution of the primate lentiviruses: evidence from Vpx and Vpr. Embo J 1992, 11:3405-3412.
-
(1992)
Embo J
, vol.11
, pp. 3405-3412
-
-
Tristem, M.1
Marshall, C.2
Karpas, A.3
-
23
-
-
0028942487
-
Progression to AIDS in the absence of a gene for Vpr or Vpx
-
Gibbs JS, Lackner AA, Lang SM, et al.: Progression to AIDS in the absence of a gene for Vpr or Vpx. J Virol 1995, 69:2378-2383.
-
(1995)
J Virol
, vol.69
, pp. 2378-2383
-
-
Gibbs, J.S.1
Lackner, A.A.2
Lang, S.M.3
-
24
-
-
0027429412
-
Incorporation of Vpr into human immunodeficiency virus type 1 virions: Requirement for the p6 region of gag and mutational analysis
-
Paxton W, Connor RI, Landau NR: Incorporation of Vpr into human immunodeficiency virus type 1 virions: requirement for the p6 region of gag and mutational analysis. J Virol 1993, 67:7229-7237.
-
(1993)
J Virol
, vol.67
, pp. 7229-7237
-
-
Paxton, W.1
Connor, R.I.2
Landau, N.R.3
-
25
-
-
34248594865
-
The cell cycle independence of HIV infections is not determined by known karyophilic viral elements
-
Yamashita M, Emerman M: The cell cycle independence of HIV infections is not determined by known karyophilic viral elements. PLoS Pathog 2005, 1:e18.
-
(2005)
PLoS Pathog
, vol.1
-
-
Yamashita, M.1
Emerman, M.2
-
26
-
-
0003124066
-
HIV-1 Vpr increases viral expression by manipulation of the cell cycle: A mechanism for selection of Vpr in vivo
-
Goh WC, Rogel ME, Kinsey CM, et al.: HIV-1 Vpr increases viral expression by manipulation of the cell cycle: a mechanism for selection of Vpr in vivo. Nat Med 1998, 4:65-71.
-
(1998)
Nat Med
, vol.4
, pp. 65-71
-
-
Goh, W.C.1
Rogel, M.E.2
Kinsey, C.M.3
-
28
-
-
0035941488
-
Cytoplasmic retention of HIV-1 regulatory protein Vpr by protein-protein interaction with a novel human cytoplasmic protein VprBP
-
Zhang S, Feng Y, Narayan O, et al.: Cytoplasmic retention of HIV-1 regulatory protein Vpr by protein-protein interaction with a novel human cytoplasmic protein VprBP. Gene 2001, 263:131-140.
-
(2001)
Gene
, vol.263
, pp. 131-140
-
-
Zhang, S.1
Feng, Y.2
Narayan, O.3
-
29
-
-
34547395804
-
Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle
-
Hrecka K, Gierszewska M, Srivastava S, et al.: Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle. Proc Natl Acad Sci U S A 2007, 104:11778-11783.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 11778-11783
-
-
Hrecka, K.1
Gierszewska, M.2
Srivastava, S.3
-
30
-
-
34247187942
-
HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1
-
Schrofelbauer B, Hakata Y, Landau NR: HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1. Proc Natl Acad Sci U S A 2007, 104:4130-4135.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 4130-4135
-
-
Schrofelbauer, B.1
Hakata, Y.2
Landau, N.R.3
-
31
-
-
34547639932
-
HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase
-
Belzile JP, Duisit G, Rougeau N, et al.: HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase. PLoS Pathog 2007, 3:e85.
-
(2007)
PLoS Pathog
, vol.3
-
-
Belzile, J.P.1
Duisit, G.2
Rougeau, N.3
-
32
-
-
33846899500
-
HIV1 Vpr arrests the cell cycle by recruiting DCAF1/VprBP, a receptor of the Cul4-DDB1 ubiquitin ligase
-
Le Rouzic E, Belaidouni N, Estrabaud E, et al.: HIV1 Vpr arrests the cell cycle by recruiting DCAF1/VprBP, a receptor of the Cul4-DDB1 ubiquitin ligase. Cell Cycle 2007, 6:182-188.
-
(2007)
Cell Cycle
, vol.6
, pp. 182-188
-
-
Le Rouzic, E.1
Belaidouni, N.2
Estrabaud, E.3
-
33
-
-
34250318465
-
DCAFs, the missing link of the CUL4-DDB1 ubiquitin ligase
-
Lee J, Zhou P: DCAFs, the missing link of the CUL4-DDB1 ubiquitin ligase. Mol Cell 2007, 26:775-780.
-
(2007)
Mol Cell
, vol.26
, pp. 775-780
-
-
Lee, J.1
Zhou, P.2
-
34
-
-
33744832621
-
With a little help from a friend: Increasing HIV transduction of monocyte-derived dendritic cells with virion-like particles of SIV(MAC)
-
Goujon C, Jarrosson-Wuilleme L, Bernaud J, et al.: With a little help from a friend: increasing HIV transduction of monocyte-derived dendritic cells with virion-like particles of SIV(MAC). Gene Ther 2006, 13:991-994.
-
(2006)
Gene Ther
, vol.13
, pp. 991-994
-
-
Goujon, C.1
Jarrosson-Wuilleme, L.2
Bernaud, J.3
-
35
-
-
33846701783
-
-
• Goujon C, Riviere L, Jarrosson-Wuilleme L, et al.: SIVSM/HIV-2 Vpx proteins promote retroviral escape from a proteasome-dependent restriction pathway present in human dendritic cells. Retrovirology 2007, 4:2. The study used VLPs to show that Vpx appears to counteract an antiviral mechanism that involves the proteasome system in DCs.
-
• Goujon C, Riviere L, Jarrosson-Wuilleme L, et al.: SIVSM/HIV-2 Vpx proteins promote retroviral escape from a proteasome-dependent restriction pathway present in human dendritic cells. Retrovirology 2007, 4:2. The study used VLPs to show that Vpx appears to counteract an antiviral mechanism that involves the proteasome system in DCs.
-
-
-
-
36
-
-
44449107162
-
-
Srivastava S, Swanson SK, Manel N, et al.: Lentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infection. PLoS Pathog 2008, 4:e1000059.
-
Srivastava S, Swanson SK, Manel N, et al.: Lentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infection. PLoS Pathog 2008, 4:e1000059.
-
-
-
-
37
-
-
44449129551
-
-
• Sharova N, Wu Y, Zhu X, et al.: Primate lentiviral Vpx commandeers DDB1 to counteract a macrophage restriction. PLoS Pathog 2008, 4:e1000057. Permissive and nonpermissive cells were fused to show that DCs contain a dominant inhibitor that is counteracted by Vpx.
-
• Sharova N, Wu Y, Zhu X, et al.: Primate lentiviral Vpx commandeers DDB1 to counteract a macrophage restriction. PLoS Pathog 2008, 4:e1000057. Permissive and nonpermissive cells were fused to show that DCs contain a dominant inhibitor that is counteracted by Vpx.
-
-
-
-
38
-
-
53449083627
-
Role of HIV-1 Vpu protein for virus spread and pathogenesis
-
Nomaguchi M, Fujita M, Adachi A: Role of HIV-1 Vpu protein for virus spread and pathogenesis. Microbes Infect 2008, 10:960-967.
-
(2008)
Microbes Infect
, vol.10
, pp. 960-967
-
-
Nomaguchi, M.1
Fujita, M.2
Adachi, A.3
-
39
-
-
44649139364
-
HIV-1 accessory proteins - ensuring viral survival in a hostile environment
-
Malim MH, Emerman M: HIV-1 accessory proteins - ensuring viral survival in a hostile environment. Cell Host Microbe 2008, 3:388-398.
-
(2008)
Cell Host Microbe
, vol.3
, pp. 388-398
-
-
Malim, M.H.1
Emerman, M.2
-
40
-
-
37849046974
-
Modulation of the severe CD4+ T-cell loss caused by a pathogenic simianhuman immunodeficiency virus by replacement of the subtype B Vpu with the Vpu from a subtype C HIV-1 clinical isolate
-
Hill MS, Ruiz A, Pacyniak E, et al.: Modulation of the severe CD4+ T-cell loss caused by a pathogenic simianhuman immunodeficiency virus by replacement of the subtype B Vpu with the Vpu from a subtype C HIV-1 clinical isolate. Virology 2008, 371:86-97.
-
(2008)
Virology
, vol.371
, pp. 86-97
-
-
Hill, M.S.1
Ruiz, A.2
Pacyniak, E.3
-
41
-
-
0030940154
-
The human immunodeficiency virus type 1 (HIV-1) Vpu protein interferes with an early step in the biosynthesis of major histocompatibility complex (MHC) class I molecules
-
Kerkau T, Bacik I, Bennink JR, et al.: The human immunodeficiency virus type 1 (HIV-1) Vpu protein interferes with an early step in the biosynthesis of major histocompatibility complex (MHC) class I molecules. J Exp Med 1997, 185:1295-1305.
-
(1997)
J Exp Med
, vol.185
, pp. 1295-1305
-
-
Kerkau, T.1
Bacik, I.2
Bennink, J.R.3
-
42
-
-
37849053288
-
Human immunodeficiency virus type 1 Vpu protein interacts with CD74 and modulates major histocompatibility complex class II presentation
-
Hussain A, Wesley C, Khalid M, et al.: Human immunodeficiency virus type 1 Vpu protein interacts with CD74 and modulates major histocompatibility complex class II presentation. J Virol 2008, 82:893-902.
-
(2008)
J Virol
, vol.82
, pp. 893-902
-
-
Hussain, A.1
Wesley, C.2
Khalid, M.3
-
43
-
-
0025139857
-
The human immunodeficiency virus type 1-specific protein Vpu is required for efficient virus maturation and release
-
Klimkait T, Strebel K, Hoggan MD, et al.: The human immunodeficiency virus type 1-specific protein Vpu is required for efficient virus maturation and release. J Virol 1990, 64:621-629.
-
(1990)
J Virol
, vol.64
, pp. 621-629
-
-
Klimkait, T.1
Strebel, K.2
Hoggan, M.D.3
-
44
-
-
33646921736
-
HIV-1 Vpu promotes release and prevents endocytosis of nascent retrovirus particles from the plasma membrane
-
Neil SJ, Eastman SW, Jouvenet N, et al.: HIV-1 Vpu promotes release and prevents endocytosis of nascent retrovirus particles from the plasma membrane. PLoS Pathog 2006, 2:e39.
-
(2006)
PLoS Pathog
, vol.2
-
-
Neil, S.J.1
Eastman, S.W.2
Jouvenet, N.3
-
45
-
-
34548392739
-
An interferon-alpha-induced tethering mechanism inhibits HIV-1 and Ebola virus particle release but is counteracted by the HIV-1 Vpu protein
-
Neil SJ, Sandrin V, Sundquist WI, et al.: An interferon-alpha-induced tethering mechanism inhibits HIV-1 and Ebola virus particle release but is counteracted by the HIV-1 Vpu protein. Cell Host Microbe 2007, 2:193-203.
-
(2007)
Cell Host Microbe
, vol.2
, pp. 193-203
-
-
Neil, S.J.1
Sandrin, V.2
Sundquist, W.I.3
-
46
-
-
38549095979
-
Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu
-
Neil SJ, Zang T, Bieniasz PD: Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu. Nature 2008, 451:425-430.
-
(2008)
Nature
, vol.451
, pp. 425-430
-
-
Neil, S.J.1
Zang, T.2
Bieniasz, P.D.3
-
47
-
-
33750470785
-
Quantitative membrane proteomics reveals new cellular targets of viral immune modulators
-
Bartee E, McCormack A, Fruh K: Quantitative membrane proteomics reveals new cellular targets of viral immune modulators. PLoS Pathog 2006, 2:e107.
-
(2006)
PLoS Pathog
, vol.2
-
-
Bartee, E.1
McCormack, A.2
Fruh, K.3
-
48
-
-
41849116366
-
-
•• Van Damme N, Goff D, Katsura C, et al.: The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein. Cell Host Microbe 2008, 3:245-252. This study independently identified BST2/tetherin as the target of Vpu.
-
•• Van Damme N, Goff D, Katsura C, et al.: The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein. Cell Host Microbe 2008, 3:245-252. This study independently identified BST2/tetherin as the target of Vpu.
-
-
-
-
49
-
-
38549128166
-
HIV/AIDS: Virus kept on a leash
-
Gottlinger HG: HIV/AIDS: virus kept on a leash. Nature 2008, 451:406-408.
-
(2008)
Nature
, vol.451
, pp. 406-408
-
-
Gottlinger, H.G.1
-
50
-
-
44949147194
-
-
• Varthakavi V, Heimann-Nichols E, Smith RM, et al.: Identification of calcium-modulating cyclophilin ligand as a human host restriction to HIV-1 release overcome by Vpu. Nat Med 2008, 14:641-647. This study identified CAML as a second potential target of Vpu using a yeast-two hybrid approach. Whether CAML regulates or otherwise interacts with tetherin/BST2 is not yet known.
-
• Varthakavi V, Heimann-Nichols E, Smith RM, et al.: Identification of calcium-modulating cyclophilin ligand as a human host restriction to HIV-1 release overcome by Vpu. Nat Med 2008, 14:641-647. This study identified CAML as a second potential target of Vpu using a yeast-two hybrid approach. Whether CAML regulates or otherwise interacts with tetherin/BST2 is not yet known.
-
-
-
|