Cell-wall thickness: Possible mechanism of acriflavine resistance in meticillin-resistant Staphylococcus aureus

Journal of Medical Microbiology

Volumn 58, Issue 3, 2009, Pages 331-336

  Kawai, Mako ^a   Yamada, Sakuo ^b,c   Ishidoshiro, Ai ^a   Oyamada, Yoshihiro ^a   Ito, Hideaki ^a   Yamagishi, Jun Ichi ^a  

^a DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

^b KAWASAKI MEDICAL SCHOOL   (Japan)

^c KAWASAKI UNIVERSITY OF MEDICAL WELFARE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACRIFLAVINE; AMPICILLIN; BENZALKONIUM CHLORIDE; BENZETHONIUM CHLORIDE; CEFALOTIN; CETRIMIDE; CHLORAMPHENICOL; CHLORHEXIDINE GLUCONATE; ERYTHROMYCIN; ETHACRIDINE LACTATE; ETHIDIUM BROMIDE; GENTAMICIN; NORFLOXACIN; NOVOBIOCIN; RHODAMINE 6G; RIFAMPICIN; SPARFLOXACIN; TETRACYCLINE; TRICLOSAN; VANCOMYCIN;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIUM ISOLATE; CELL MEMBRANE PERMEABILITY; CELL SIZE; CELL SURFACE; CELL WALL; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL;

ACRIFLAVINE; ANTI-INFECTIVE AGENTS, LOCAL; ANTIPORTERS; BACTERIAL PROTEINS; CELL WALL; DRUG RESISTANCE, BACTERIAL; MEMBRANE TRANSPORT PROTEINS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION;

EID: 61449180105     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/jmm.0.004184-0     Document Type: Article

References (30)

1. Aeschlimann, J. R., Dresser, L. D., Kaatz, G. W. & Rybak, M. J. (1999). Effects of NorA inhibitors on in vitro antibacterial activities and postantibiotic effects of levofloxacin, ciprofloxacin, and norfloxacin in genetically related strains of Staphylococcus aureus. Antimicrob Agents Chemother 43, 335-340.
2. Alam, M. M., Ishino, M. & Kobayashi, N. (2003a). Analysis of genomic diversity and evolution of the low-level antiseptic resistance gene smr in Staphylococcus aureus. Microb Drug Resist 9, S1-S7.
3. Alam, M. M., Kobayashi, N., Uehara, N. & Watanabe, N. (2003b). Analysis on distribution of high-level antiseptic resistance genes qacA and qacB in human clinical isolates of Staphylococcus aureus. Microb Drug Resist 9, 109-121.
4. Beenken, K. E., Dunman, P. M., McAleese, F., Macapagal, D., Murphy, E., Projan, S. J., Blevins, J. S. & Smeltzer, M. S. (2004). Global gene expression in Staphylococcus aureus biofilm. J Bacteriol 186, 4665-4684.
5. Bjorland, J., Steinum, T., Sunde, M., Waage, S. & Heir, E. (2003). Novel plasmid-borne gene qacJ mediates resistance to quaternary ammonium compounds in equine Staphylococcus aureus Staphylococcus simulans and Staphylococcus intermedius. Antimicrob Agents Chemother 47, 3046-3052.
6. CLSI (2003). Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically, 6th edn. Approved Standard M7-A6. Wayne, PA: Clinical and Laboratory Standards Institute.
7. Cui, L., Murakami, H., Kuwahara-Arai, K., Hanaki, H. & Hiramatsu, K. (2000). Contribution of a thickened cell wall and its glutamine nonamidated component to the vancomycin resistance expressed by Staphylococcus aureus Mu50. Antimicrob Agents Chemother 44, 2276-2285.
8. Cui, L., Xiaoxue, M., Sato, K., Okuma, K., Tenover, F. C., Mamizaka, E. M., Gemmell, C. G., Kim, M.-N., Poly, M.-C. & other authors (2003). Cell wall thickening is a common feature of vancomycin resistance in Staphylococcus aureus. J Clin Microbiol 41 , 5-14.
9. Gibbons, S., Oluwatuyi, M. & Kaatz, G. W. (2003). A novel inhibitor of multidrug efflux pumps in Staphylococcus aureus. J Antimicrob Chemother 51, 13-17.
10. Gilbert, P. & McBain, J. A. (2003). Potential impact of increased use of biocides in consumer products on prevalence of antibiotic resistance. Clin Microbiol Rev 16, 189-208.
11. Hiramatsu, K., Hanaki, H., Ino, T., Yabuta, K., Oguri, T. & Tenover, F. C. (1997). Methicillin-resistant Staphylococcus aureus clinical strain with reduced vancomycin susceptibility. J Antimicrob Chemother 40, 135-136.
12. Huang, J., O'Toole, P. W., Shen, W., Amrine-Madsen, H., Jiang, X., Lobo, N.,Palmer,L.M., Voelker, L.,Fan,F., Gwynn, M. N. &McDevitt, D. (2004). Novel chromosomally encoded multidrug efflux transporter MedA in Staphylococcus aureus. Antimicrob Agents Chemother 48, 909-917.
13. Hudson, M. C. & Curtiss, R., III (1990). Regulation of expression of Streptococcus mutans genes important to virulence. Infect Immun 58, 464-470.
14. Kaatz, G. W., Seo, S. M., O'Brien, L., Wahiduzzaman, M. & Foster, T. J. (2000). Evidence for the existence of multidrug efflux transporter distinct from NorA in Staphylococcus aureus. Antimicrob Agents Chemother 44, 1404-1406.
15. Mayer, S., Boos, M., Beyer, A., Fluit, A. C. & Schmitz, F. J. (2001). Distribution of antiseptic resistance genes qacA, qacB and qacC in 497 methicillin-resistant and -susceptible European isolates of Staphylococcus aureus. J Antimicrob Chemother 47, 896-897.
16. McDonnell, G. & Russell, A. D. (1999). Antiseptics and disinfectants:activity, action, and resistance. Clin Microbiol Rev 12, 147-179.
17. Nishino, T. (1975). An electron microscopic study of antagonism between cephalexin and erythromycin in Staphylococcus aureus. Jpn J Microbiol 19, 53-63.
18. Noguchi, N., Hase, M., Kitta, M., Sasatsu, M., Deguchi, K. & Kono, M. (1999). Antiseptic susceptibility and distribution of antiseptic-resistance genes in methicillin-resistant Staphylococcus aureus. FEMS Microbiol Lett 172, 247-253.
19. Paulsen, I. T., Brown, M. H. & Skurray, R. A. (1996). Protondependent multidrug efflux systems. Microbiol Rev 60, 575-608.
20. Piddock, L. J. (2006). Clinically relevant chromosomally encoded multidrug resistance efflux pumps in bacteria. Clin Microbiol Rev 19, 382-402.
21. Poole, K. (2002). Mechanisms of bacterial biocide and antiseptic resistance. J Appl Microbiol 92, 55S-64S
22. Reifsteck, F., Wee, S. & Wilkinson, B. J. (1987). Hydrophobicity-hydrophilicity of staphylococci. J Med Microbiol 24, 65-73.
23. Rosenberg, M. & Rosenberg, E. (1981). Role of adherence in growth of Acinetobacter calcoaceticus RAG-1 on hexadecane. J Bacteriol 148, 51-57.
24. Rouch, D. A., Cram, D. S., DiBerardino, D., Littlejohn, T. G. &Skurray, R. A. (1990). Efflux-mediated antiseptic gene qacA from Staphylococcus aureus: common ancestry with tetracycline- and sugar-transport proteins. Mol Microbiol 4, 2051-2062.
25. Russell, A. D. (2003). Biocide use and antibiotic resistance: the relevance of laboratory findings to clinical and environmental situations. Lancet Infect Dis 3, 794-803.
26. Sasatsu, M., Shima, K., Shibata, Y. & Kono, M. (1989). Nucleotide sequence of a gene that encodes resistance to ethidium bromide from a transferable plasmid in Staphylococcus aureus. Nucleic Acids Res 17, 10103.
27. Sieradzki, K. & Tomasz, A. (2003). Alterations of cell wall structure and metabolism accompany reduced susceptibility to vancomycin in an isogenic series of clinical isolates of Staphylococcus aureus. J Bacteriol 185, 7103-7110.
28. Suller, M. T. & Russell, A. D. (1999). Antibiotic and biocide resistance in methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococcus. J Hosp Infect 43, 281-291.
29. Wadström, T. (1990). Hydrophobic characteristics of staphylococci:role of surface structures and role in adhesion and host colonization. In Microbial Cell Surface Hydrophobicity, pp. 315-333. Edited by R. J.Doyle & M. Rosenberg. Washington, DC: American Society for Microbiology.
30. Yamada, S. & Matsumoto, A. (1990). Surface properties of Staphylococcus aureus affecting chemiluminescence response of human phagocytes. Microbiol Immunol 34, 809-817.