Acute Normal Tissue Reactions in Head-and-Neck Cancer Patients Treated With IMRT: Influence of Dose and Association With Genetic Polymorphisms in DNA DSB Repair Genes

International Journal of Radiation Oncology Biology Physics

Volumn 73, Issue 4, 2009, Pages 1187-1195

  Werbrouck, Joke ^a   De Ruyck, Kim ^a   Duprez, Fréderic ^b   Veldeman, Liv ^b   Claes, Kathleen ^b   Van Eijkeren, Marc ^b   Boterberg, Tom ^b   Willems, Petra ^a   Vral, Anne ^a   De Neve, Wilfried ^b   Thierens, Hubert ^a  

^a GHENT UNIVERSITY   (Belgium)

^b GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

Acute normal tissue reactions; DNA DSB repair; Dose volume histogram; Head and neck cancer; Polymorphisms

Indexed keywords

AGRICULTURAL PRODUCTS; COSMIC RAYS; DNA; GENES; MUSCLE; NUCLEIC ACIDS; PATIENT MONITORING; PHYSICAL THERAPY; POLYMORPHISM; PUMPS; RADIOTHERAPY; REPAIR; RISK ANALYSIS; RISK ASSESSMENT; SAFETY FACTOR; TERMINOLOGY;

ACUTE NORMAL TISSUE REACTIONS; ADVERSE EVENTS; ANALYSIS MODELS; COMMON TERMINOLOGY CRITERION; CRITICAL STRUCTURES; DNA DSB REPAIR; DOSE-VOLUME HISTOGRAM; GENETIC POLYMORPHISMS; HEAD-AND-NECK CANCER; HIGH SENSITIVITIES; INTENSITY-MODULATED RADIATION THERAPIES; MEAN DOSE; MUCOSITIS; ORAL CAVITIES; POLYMERASE CHAIN REACTIONS; PREDICTION MODELS; RESTRICTION FRAGMENT LENGTH POLYMORPHISMS; SINGLE-BASE EXTENSIONS;

ASSOCIATION REACTIONS;

DNA;

ACUTE RADIATION SYNDROME; ADULT; AGED; ARTICLE; CANCER PATIENT; DERMATITIS; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE SEVERITY; DNA REPAIR; DYSPHAGIA; FEMALE; GENE; GENETIC POLYMORPHISM; GENOMICS; GENOTYPE; HEAD AND NECK CANCER; HISTOGRAM; HUMAN; INTENSITY MODULATED RADIATION THERAPY; MAJOR CLINICAL STUDY; MALE; MOUTH CAVITY; MUCOSA INFLAMMATION; NUCLEOTIDE SEQUENCE; OUTCOME ASSESSMENT; POLYMERASE CHAIN REACTION; PREDICTION; PRIORITY JOURNAL; RADIATION DOSE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK ASSESSMENT; SCORING SYSTEM; SENSITIVITY AND SPECIFICITY; SKELETAL MUSCLE;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, NUCLEAR; ARABIDOPSIS PROTEINS; CARCINOMA, SQUAMOUS CELL; DEGLUTITION DISORDERS; DNA LIGASES; DNA REPAIR; DNA-BINDING PROTEINS; FEMALE; HEAD AND NECK NEOPLASMS; HUMANS; MALE; MIDDLE AGED; MOUTH; MOUTH MUCOSA; PHARYNGEAL MUSCLES; POLYMORPHISM, GENETIC; RAD51 RECOMBINASE; RADIODERMATITIS; RADIOTHERAPY DOSAGE; RADIOTHERAPY, INTENSITY-MODULATED; REGRESSION ANALYSIS;

EID: 61349169578     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2008.08.073     Document Type: Article

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