The microRNA-argonaute complex: A platform for mRNA modulation

RNA Biology

Volumn 5, Issue 3, 2008, Pages

  Hammell, Christopher M ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Argonaute; Gene regulation; MicroRNA; MiRNA; mRNA

Indexed keywords

ARGONAUTE PROTEIN; MESSENGER RNA; MICRORNA; RNA BINDING PROTEIN; INITIATION FACTOR;

COMPLEX FORMATION; GENE ACTIVITY; GENE FUNCTION; GENE LOCATION; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; REVIEW; RNA DEGRADATION; RNA METABOLISM; RNA STABILITY; RNA TRANSLATION; ANIMAL; GENETICS; HUMAN; METABOLISM;

ANIMALS; EUKARYOTIC INITIATION FACTORS; HUMANS; MICRORNAS; RNA, MESSENGER;

EID: 54349096334     PISSN: 15476286     EISSN: 15558584     Source Type: Journal    
DOI: 10.4161/rna.5.3.6570     Document Type: Review

References (44)

1. Lagos-Quintana M, Rauhut R, Lendeckel W and Tuschl T. Identification of novel genes coding for small expressed RNAs. Science 2001; 294:853-8.
2. Lau NC, Lim LP, Weinstein EG and Bartel DP. An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 2001; 294:858-62.
3. Lee RC and Ambros V. An extensive class of small RNAs in Caenorhabditis elegans. Science 2001; 294:862-4.
4. Eulalio A, Huntzinger E and Izaurralde E. Getting to the root of miRNA-mediated gene silencing. Cell 2008; 132:9-14.
5. Wu L and Belasco JG. Let me count the ways: mechanisms of gene regulation by miRNAs and siRNAs. Mol Cell 2008; 29:1-7.
6. Filipowicz W, Bhattacharyya SN and Sonenberg N. Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet 2008; 9:102-14.
7. Johnston RJ and Hobert O. A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans. Nature 2003; 426:845-9.
8. Brennecke J, Hipfner DR, Stark A, Russell RB and Cohen SM. bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila. Cell 2003; 113:25-36.
9. Slack FJ, et al. The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. Mol Cell 2000; 5:659-69.
10. Moss EG, Lee RC and Ambros V. The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA. Cell 1997; 88:637-46.
11. Lee RC, Feinbaum RL and Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993; 75:843-54.
12. Wightman B, Ha I and Ruvkun G. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 1993; 75:855-62.
13. Abbott AL, et al. The let-7 MicroRNA family members mir-48, mir-84 and mir-241 function together to regulate developmental timing in Caenorhabditis elegans. Dev Cell 2005; 9:403-14.
14. Karres JS, Hilgers V, Carrera I, Treisman J and Cohen SM. The conserved microRNA miR-8 tunes atrophin levels to prevent neurodegeneration in Drosophila. Cell 2007; 131:136-45.
15. Simon DJ, et al. The microRNA miR-1 regulates a MEF-2-dependent retrograde signal at neuromuscular junctions. Cell 2008; 133:903-15.
16. Kiriakidou M, et al. An mRNA m7G cap binding-like motif within human Ago2 represses translation. Cell 2007; 129:1141-51.
17. Thermann R and Hentze MW. Drosophila miR2 induces pseudo-polysomes and inhibits translation initiation. Nature 2007; 447:875-8.
18. Mathonnet G, et al. MicroRNA inhibition of translation initiation in vitro by targeting the cap-binding complex eIF4F. Science 2007; 317:1764-7.
19. Seggerson K, Tang L and Moss EG. Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation. Dev Biol 2002; 243:215-25.
20. Olsen PH and Ambros V. The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation. Dev Biol 1999; 216:671-80.
21. Bhattacharyya SN, Habermacher R, Martine U, Closs EI and Filipowicz W. Stress-induced reversal of microRNA repression and mRNA P-body localization in human cells. Cold Spring Harb Symp Quant Biol 2006; 71:513-21.
22. Nottrott S, Simard MJ and Richter JD. Human let-7a miRNA blocks protein production on actively translating polyribosomes. Nat Struct Mol Biol 2006; 13:1108-14.
23. Maroney PA, Yu Y, Fisher J and Nilsen TW. Evidence that microRNAs are associated with translating messenger RNAs in human cells. Nat Struct Mol Biol 2006; 13:1102-7.
24. Liu J, et al. Argonaute2 is the catalytic engine of mammalian RNAi. Science 2004; 305:1437-41.
25. Yekta S, Shih IH and Bartel DP. MicroRNA-directed cleavage of HOXB8 mRNA. Science 2004; 304:594-6.
26. Bagga S, et al. Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation. Cell 2005; 122:553-63.
27. Behm-Ansmant I, et al. mRNA degradation by miRNAs and GW182 requires both CCR4: NOT deadenylase and DCP1:DCP2 decapping complexes. Genes Dev 2006; 20:1885-98.
28. Chendrimada TP, et al. MicroRNA silencing through RISC recruitment of eIF6. Nature 2007; 447:823-8.
29. Lim LP, et al. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 2005; 433:769-73.
30. Grimson A, et al. MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol Cell 2007; 27:91-105.
31. Giraldez AJ, et al. Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs. Science 2006; 312:75-9.
32. Wakiyama M, Takimoto K, Ohara O and Yokoyama S. Let-7 microRNA-mediated mRNA deadenylation and translational repression in a mammalian cell-free system. Genes Dev 2007; 21:1857-62.
33. Eulalio A, Huntzinger E and Izaurralde E. GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay. Nat Struct Mol Biol 2008; 15:346-53.
34. Eulalio A, et al. Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing. Genes Dev 2007; 21:2558-70.
35. Leung AK, Calabrese JM and Sharp PA. Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules. Proc Natl Acad Sci USA 2006; 103:18125-30.
36. Chu CY and Rana TM. Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54. PLoS Biol 2006; 4:210.
37. Eulalio A, Behm-Ansmant I, Schweizer D and Izaurralde E. P-body formation is a consequence, not the cause, of RNA-mediated gene silencing. Mol Cell Biol 2007; 27:3970-81.
38. Parker R and Sheth U. P bodies and the control of mRNA translation and degradation. Mol Cell 2007; 25:635-46.
39. Wilusz CJ, Wormington M and Peltz SW. The cap-to-tail guide to mRNA turnover. Nat Rev Mol Cell Biol 2001; 2:237-46.
40. Vasudevan S and Steitz JA. AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute2. Cell 2007; 128:1105-18.
41. Vasudevan S, Tong Y and Steitz JA. Switching from repression to activation: microRNAs can upregulate translation. Science 2007; 318:1931-4.
42. Neumuller RA, et al. Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage. Nature 2008.
43. Ishizuka A, Siomi MC and Siomi H. A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins. Genes Dev 2002; 16:2497-508.
44. Jing Q, et al. Involvement of microRNA in AU-rich element-mediated mRNA instability. Cell 2005; 120:623-34.