Identification of drostanolone and 17-methyldrostanolone metabolites produced by cryopreserved human hepatocytes

Steroids

Volumn 74, Issue 3, 2009, Pages 306-314

  Gauthier, Julie ^a   Goudreault, Danielle ^a   Poirier, Donald ^b   Ayotte, Christiane ^a  

^a INRS INSTITUT ARMAND FRAPPIER   (Canada)

^b LAVAL UNIVERSITY   (Canada)

Author keywords

Drostanolone; GC MS; Hepatocytes; Metabolites; Methyldrostanolone

Indexed keywords

17 METHYLDROSTANOLONE DERIVATIVE; 17BETA HYDROXY 17ALPHA METHYL 2 OXIRANE 5ALPHA ANDROSTANE 3 ONE; 2 METHYLENE 17ALPHA METHYL 5ALPHA ANDROSTANE 3BETA,17BETA DIOL; 2ALPHA 17ALPHA DIMETHYL 17BETA HYDROXY 5ALPHA ANDROSTAN 3 ONE; 2ALPHA,17ALPHA DIMETHYL 17BETA HYDROXY 5ALPHA ANDROSTAN 3 ONE; 2BETA,17ALPHA DIMETHYL 5ALPHA ANDROSTANE 2ALPHA,3BETA,17BETA TRIOL; 3,3 ETHYLENEDIOXY 2ALPHA METHYL 5ALPHA ANDROSTAN 17 ONE; 3,3 ETHYLENEDIOXY 2ALPHA METHYL 5ALPHA ANDROSTAN 17BETA OL; 3,3 ETHYLENEDIOXY 2ALPHA,17ALPHA DIMETHYL 5ALPHA ANDROSTAN 17BETA OL; 3ALPHA HYDROXYSTEROID DEHYDROGENASE; ANDROGEN; ANDROSTANOLONE; ANDROSTANOLONE DERIVATIVE; CHLOROTRIMETHYLSILANE; DROSTANOLONE; DROSTANOLONE DERIVATIVE; DRUG METABOLITE; EPIANDROSTERONE; ETIOCHOLANOLONE; TRIMETHYLSILYL DERIVATIVE; UNCLASSIFIED DRUG;

ANDROGEN METABOLISM; ARTICLE; BIOTRANSFORMATION; CHEMICAL STRUCTURE; CRYOPRESERVATION; CULTURE MEDIUM; DRUG IDENTIFICATION; GAS CHROMATOGRAPHY; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HYDROXYLATION; INCUBATION TIME; LIVER CELL; MASS FRAGMENTOGRAPHY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STEREOCHEMISTRY;

ANABOLIC AGENTS; ANDROSTANOLS; CELLS, CULTURED; CHROMATOGRAPHY, GAS; CRYOPRESERVATION; HEPATOCYTES; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MOLECULAR STRUCTURE;

EID: 61349134751     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2008.11.002     Document Type: Article

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