NAT2 fast acetylator genotype and MGMT promoter methylation may contribute to gender difference in K-RAS mutation occurrence in Taiwanese colorectal cancer

Environmental and Molecular Mutagenesis

Volumn 50, Issue 2, 2009, Pages 127-133

  Huang, Chi Chou ^a   Chien, Wen Pin ^b   Wong, Ruey Hong ^b   Cheng, Ya Wen ^b   Chen, Meng Cheng ^a   Lee, Huei ^b  

^a CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Colorectal cancer; K RAS mutation; MGMT hypermethylation; NAT2 genotypes; Taiwan

Indexed keywords

ARYLAMINE ACETYLTRANSFERASE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; DNA; DNA METHYLTRANSFERASE; MGMT PROTEIN, HUMAN; NAT2 PROTEIN, HUMAN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; TUMOR SUPPRESSOR PROTEIN;

ACETYLATOR PHENOTYPE; AGED; ARTICLE; CANCER RISK; CLINICAL TRIAL; COLORECTAL CANCER; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENE MUTATION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; ONCOGENE K RAS; POLYMERASE CHAIN REACTION; PROMOTER REGION; PROTEIN METHYLATION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK ASSESSMENT; SEX DIFFERENCE; TAIWAN; ACETYLATION; COLORECTAL TUMOR; GENETICS; METABOLISM; METHYLATION; MIDDLE AGED; MUTATION; ONCOGENE RAS; SEXUAL DEVELOPMENT;

ACETYLATION; AGED; ARYLAMINE N-ACETYLTRANSFERASE; COLORECTAL NEOPLASMS; DNA MODIFICATION METHYLASES; DNA REPAIR ENZYMES; DNA, NEOPLASM; FEMALE; GENES, RAS; HUMANS; MALE; METHYLATION; MIDDLE AGED; MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; SEX CHARACTERISTICS; TAIWAN; TUMOR SUPPRESSOR PROTEINS;

EID: 60849106685     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.20444     Document Type: Article

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