Effects of gabapentin and pregabalin on K+-evoked 3H-GABA and 3H-glutamate release from human neocortical synaptosomes

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 379, Issue 4, 2009, Pages 361-369

  Brawek, B ^a   Loffler M ^a   Weyerbrock, A ^a   Feuerstein, T J ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

GABA release; Gabapentin; Glutamate release; Human neocortex; Pregabalin

Indexed keywords

4 AMINOBUTYRIC ACID; ALPHA2DELTA VOLTAGE SENSITIVE CALCIUM CHANNEL; CALCIUM CHANNEL; CALCIUM ION; GABAPENTIN; GLUTAMIC ACID; POTASSIUM ION; PREGABALIN; TRITIUM; UNCLASSIFIED DRUG;

4 AMINOBUTYRIC ACID RELEASE; ADOLESCENT; ADULT; AGED; ANTICONVULSANT ACTIVITY; ARTICLE; CHILD; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; EXOCYTOSIS; FEMALE; HUMAN; HUMAN TISSUE; MALE; NEOCORTEX; SYNAPTOSOME;

ADOLESCENT; ADULT; AGED; AMINES; AMINO ACIDS, CYCLIC; ANTICONVULSANTS; ASPARTIC ACID; CALCIUM CHANNEL BLOCKERS; CHILD; CHILD, PRESCHOOL; CYCLOHEXANECARBOXYLIC ACIDS; EXOCYTOSIS; FEMALE; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; HUMANS; INFANT; ISOLEUCINE; MALE; MIDDLE AGED; NEOCORTEX; NEUROTRANSMITTER UPTAKE INHIBITORS; NIPECOTIC ACIDS; OXIMES; POTASSIUM; SYNAPTOSOMES; TACROLIMUS; YOUNG ADULT;

EID: 60849087941     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-008-0370-z     Document Type: Article

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