A computational analysis of SARS cysteine proteinase-octapeptide substrate interaction: Implication for structure and active site binding mechanism

BMC Bioinformatics

Volumn 10, Issue SUPPL. 1, 2009, Pages

  Phakthanakanok, Krongsakda ^a   Ratanakhanokchai, Khanok ^a   Kyu, Khin Lay ^a   Sompornpisut, Pornthep ^b   Watts, Aaron ^c   Pinitglang, Surapong ^d  

^a KING MONGKUT'S UNIVERSITY OF TECHNOLOGY THONBURI   (Thailand)

^b CHULALONGKORN UNIVERSITY   (Thailand)

^c UNIVERSITY OF EXETER   (United Kingdom)

^d UNIVERSITY OF THE THAI CHAMBER OF COMMERCE   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTATIONAL ANALYSIS; ELECTROSTATIC BONDING; ENZYME-SUBSTRATE COMPLEXES; MOLECULAR DYNAMICS SIMULATIONS; NEGATIVELY CHARGED; SEVERE ACUTE RESPIRATORY SYNDROME VIRUS; SPECIFIC SUBSTRATES; SUBSTRATE INTERACTION;

AMINO ACIDS; BINDING ENERGY; ENZYMES; MOLECULAR DYNAMICS; VIRUSES; BIOINFORMATICS;

DISEASES;

3C LIKE PROTEINASE, CORONAVIRUS; 3C-LIKE PROTEINASE, CORONAVIRUS; CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR; OLIGOPEPTIDE; VIRUS PROTEIN;

ARTICLE; BINDING SITE; BIOLOGY; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYMOLOGY; HYDROGEN BOND; METABOLISM; METHODOLOGY; PROTEIN CONFORMATION; SARS CORONAVIRUS; STRUCTURE ACTIVITY RELATION;

BINDING SITES; CATALYTIC DOMAIN; COMPUTATIONAL BIOLOGY; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; HYDROGEN BONDING; MODELS, MOLECULAR; OLIGOPEPTIDES; PROTEIN CONFORMATION; SARS VIRUS; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; VIRAL PROTEINS;

SARS CORONAVIRUS;

EID: 60849087677     PISSN: None     EISSN: 14712105     Source Type: Journal    
DOI: 10.1186/1471-2105-10-S1-S48     Document Type: Conference Paper

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