Bioreductive activation of quinone antitumor drugs by mitochondrial voltage-dependent anion channel 1

Anatomical Science International

Volumn 83, Issue 4, 2008, Pages 261-266

  Simamura, Eriko ^a   Shimada, Hiroki ^a   Ishigaki, Yasuhito ^a   Hatta, Toshihisa ^a   Higashi, Nobuaki ^a   Hirai, Kei Ichi ^a  

^a KANAZAWA MEDICAL UNIVERSITY   (Japan)

Author keywords

Blue native PAGE; Furanonaphthoquinone; Menadione; Reactive oxygen species; Voltagedependent anion channel 1

Indexed keywords

1,4 NAPHTHOQUINONE DERIVATIVE; 2 METHYL 5(OR 8) HYDROXY FURANONAPHTHOQUINONE; 2 METHYL FURANONAPHTHOQUINONE; ANTINEOPLASTIC AGENT; DOXORUBICIN; FURANONAPHTHOQUINONE; HYDROGEN PEROXIDE; MENADIONE; MITOMYCIN C; QUINONE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; UNCLASSIFIED DRUG; VOLTAGE DEPENDENT ANION CHANNEL 1; 2 METHYL 8 HYDROXYNAPHTHO(2,3 B)FURAN 4,9 DIONE; 2-METHYL-8-HYDROXYNAPHTHO(2,3-B)FURAN-4,9-DIONE; MITOMYCIN; NAPHTHOQUINONE; NICOTINAMIDE ADENINE DINUCLEOTIDE; VDAC1 PROTEIN, HUMAN;

ARTICLE; CANCER CELL; CANCER CHEMOTHERAPY; CATALYSIS; DRUG ACTIVATION; DRUG CYTOTOXICITY; DRUG SENSITIVITY; DRUG TARGETING; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MITOCHONDRION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PURIFICATION; APOPTOSIS; CELL LINE; HELA CELL; METABOLISM; OXIDATION REDUCTION REACTION; PHYSIOLOGY;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE; DOXORUBICIN; HELA CELLS; HUMANS; HYDROGEN PEROXIDE; MITOCHONDRIA; MITOMYCIN; NAD; NAPHTHOQUINONES; OXIDATION-REDUCTION; QUINONES; VITAMIN K 3; VOLTAGE-DEPENDENT ANION CHANNEL 1;

EID: 60749089670     PISSN: 14476959     EISSN: 1447073X     Source Type: Journal    
DOI: 10.1111/j.1447-073x.2008.00241.x     Document Type: Article

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