A unique cytosolic activity related but distinct from NQO1 catalyses metabolic activation of mitomycin C

British Journal of Cancer

Volumn 82, Issue 7, 2000, Pages 1305-1311

  Joseph, P ^a   Jaiswal, A K ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

A unique cytosolic activity; DNA cross linking; Mechanism of activation; Mitomycin C; NAD(P)H:quinone oxidoreductase1 (NQO1)

Indexed keywords

COMPLEMENTARY DNA; DNA; MENADIONE; MITOMYCIN C; OXIDOREDUCTASE; OXYGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHO CELL; COLON; CONTROLLED STUDY; CYTOSOL; DNA CROSS LINKING; DRUG ACTIVATION; DRUG CYTOTOXICITY; GENE DISRUPTION; GENE EXPRESSION; HUMAN; HUMAN CELL; HYPOXIA; LIVER; METABOLIC ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0034020172     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1054/bjoc.1999.1096     Document Type: Article

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