Apoptosis and epithelial phagocytosis in mitomycin C-treated human pulmonary adenocarcinoma A549 cells

Tissue and Cell

Volumn 33, Issue 2, 2001, Pages 161-168

  Simamura, E ^a   Hirai, K I ^a   Shimada, H ^a   Koyama, J ^b  

^a KANAZAWA MEDICAL UNIVERSITY   (Japan)

^b KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Adenocarcinoma cell; Apoptosis; Electron microscopy; Epithelial cell; Mitomycin C; Phagocytosis

Indexed keywords

MITOMYCIN C;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CHROMATIN CONDENSATION; CYTOSOL; CYTOTOXICITY; DENSE BODY; ELECTRON MICROSCOPY; GOLGI COMPLEX; HETEROCHROMATIN; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; LUNG ALVEOLUS EPITHELIUM; MITOCHONDRION; MYELIN SHEATH; PHAGOCYTOSIS; PHAGOSOME; ROUGH ENDOPLASMIC RETICULUM; SMOOTH ENDOPLASMIC RETICULUM; TONOFILAMENT;

EID: 0035303388     PISSN: 00408166     EISSN: None     Source Type: Journal    
DOI: 10.1054/tice.2000.0167     Document Type: Article

References (36)

1. Carter, S.K. and Crooke, S.T. 1979. Mitomycin C. Current Status and New Developments. Academic Press, New York.
2. Conover, T.E. and Ernster, L. 1960. DT-diaphorase. IV. Coupling of exramitochondrial reduced pyridine nucleotide oxidation to mitochondrial respiratory chain. Biochem. Bionphys. Acta., 67, 268-280.
3. Danielson, L., Ernster, L. and Ljunggren, M. 1960. Selective extraction of DT-diaphorase from mitochondria and microsomes. Acta. Chem. Scand., 14, 1837-1838.
4. Devitt, A., Moffatt, O.D., Raykundalia, C., Capra, J.D., Simmons, D.L. and Gregory, C.D. 1998. Human CD14 mediates recognition and phagocytosis of apoptotic cells. Nature, 392, 505-509.
5. Dini, L., Autuori, F., Lentini, A., Oliverio, S. and Piacentini, M. 1992. The clearance of apoptotic cells in the liver is mediated by the asialoglycoprotein receptor. FEBS Lett., 296, 174-178.
6. Dini, L., Lentini, A., Diez, G.D., Rocha, M., Falasca, L., Serafino, L. and Vidal-Vanaclocha, F. 1995. Phagocytosis of apoptotic bodies by liver endothelial cells. J. Cell. Sci., 108, 967-973.
7. Durham, S.K. and Castleman, W.L. 1985. Pulmonary lesions induces by 3-methylindole in mice. Am. J. Pathol., 121, 128-137.
8. Edlund, C., Elhrmammer, A. and Dallner, G. 1982. Distribution of newly synthesized DT-diaphorase in rat liver. Biosci. Rep., 2.
9. Forkert, P.G. and Reynolds, E.S. 1982. 1,1-Dichloroethylene-induced pulmonary injury. Exp. Lung Res., 3, 57-68.
10. Forkelt, P.G., Sylvesre, P.L. and Poland J.S. 1985. Lung injury induced by trichloroethylene. Toxicology, 35, 143-160.
11. Fukasawa, M., Adachi, H., Hirota, K., Tsujimoto, M., Arai, H. and Inoue, K. 1996. SRBI, a class B scavenger receptor, recognizes both negatively charged liposomes and apoptotic cells. Exp. Cell. Res., 222, 246-250.
12. Godar, D.E. and Lucas, A.D. 1995. Spectral dependence of UV-induced immediate and delayed apoptosis: the role of membrane and DNA damage. Photochem. Photobiol., 62, 108-113.
13. Gumucio, J.J., DeMason, L.J., Miller, D.L., Krezoski, S.O. and Keener, M. 1978. Induction of cytochrome P-450 in a selective subpopulation of hepatocytes. Am. J. Physiol., 234, C102-109.
14. Hirai, K.-I., Koyama, J., Pan, J., Simamura, E., Shimada, H., Yamori, T., Sato, S., Tagahara, K. and Tsuruo, T. 1999. Furan onaphthoquinone analogs possessing preferential antitumor activity compared to normal cells. Cancer Detect. Prev., 23, 539-550.
15. 5 reductase. Cancer Res., 53, 4907-4912.
16. Iyer, V.N. and Szybalski, W. 1964. Mitomycin C and porfiromycin: chemical mechanism and crosslinking of DNA. Science., 145, 55-58.
17. Michael, R., Vrensen, G.F., van Marle, J., Gan, L. and Soderberg, P.G. 1998. Apoptosis in the rat lens after in vivo threshold dose ultraviolet irradiation. Invest. Ophthalmol. Vis. Sci., 39, 2681-2687.
18. Micheau, O., Hammann, A., Solary, E. and Dimanche-Boitrel, M.-T. 1999. STAT-1-independent up regulation of FADD and procaspase-3 and -8 in cancer cells treated with cytotoxic drugs. Biochem. Biophys. Res. Commun., 256, 603-607.
19. Moore, H.W. 1977. Bioactivation as a model for drug design bioreductive alkylation. Science, 197, 527-532.
20. Pan, J., Hirari, K.-I., Simamura, E., Koyama, J., Shimada, H. and Kuwabara, S. 1997. Mitochondrial damage by a new antitumour agent furanonaphthoquinone derivative in human cervical cancer HeLa cells. J. Electron. Microsc., 46, 181-187.
21. Pan, J., Koyama, J., Matayoshi, A. and Hirai, K.-I. 1999. Structural injury of osteosarcoma mitochondria by a novel antitumour agent, 2-methylfuranonaphthoquinone. J. Electron Microsc., 48, 449-454.
22. Pan, S.S., Andrews, P.A., Glover, C.J. and Bachur, N.R. 1984. Reductive activation of mitomycin C and mitomycin C metabolites catalyzed by NADPH-cytochrome P-450 reductase and xanthine oxidase. J. Biol. Chem., 259, 959-966.
23. Platt, N., Suzuki, H., Kurihara, Y., Kodama, T. and Gordon, S. 1996. Role for the class A macrophage scavenger receptor in the phagocytosis of apoptotic thymocytes in vitro. Proc. Natl. Acad. Sci. U. S. A., 93, 12456-12460.
24. Platt, N., Silva R.P. da and Gordon, S. 1998. Recognizing death: the phagocytosis of apoptosis cells. Trends Cell Biol., 8, 365-372.
25. Savill, J., Fadok, V., Henson, P. and Haslett, C. 1993. Phagocyte recognition of cells undergoing apoptosis. Immunol. Today., 14, 131-136.
26. Savill, J. 1997. Recognition and phagocytosis of cells undergoing apoptosis. Br. Med. Bull., 53, 491-508.
27. Sesame, H.A., Castro, J.A. and Gillete, J.R. 1968. Studies on the destruction of liver microsomal cytochrome-p-450 by carbon tetrachloride administration. Biochem. Pharmacol., 17, 1759.
28. Shindo, H., Ogura, T., Masuno, T., Hayashi, S. and Kishimoto, S. 1985. Induction of activated macrophages by intraperitoneal injection of mitomycin C in mice. Cancer Immunol. Immunother., 20, 145-150.
29. Shiratsuchi, A., Kawasaki, Y., Ikemoto, M., Arai, H. and Nakanishi, Y. 1999. Role of class B scavenger receptor type I in phagocytosis of apoptotic rat spermatogenic cells by Sertoli cells. J. Biol. Chem., 274, 5901-5908.
30. Shui, Y., Sasaki, H., Pan, J., Hata, I., Kojima, M., Yamada, Y., Hirai, K.-I. Takahashi, N. and Sasaki, K. 2000. Morphological observation on cell death and phagocytosis induced by ultraviolet irradiation in a cultured human lens epithelial cell line. Exp. Eye. Res., 71, 609-618.
31. Spanswick, V.J., Cummings, J. and Smyth, J.F. 1996. Enzymology of mitomycin C metabolic activation in tumour tissue. Characterization of a novel mitochondrial reductase. Biochem. Pharmacol., 51, 1623-1630.
32. Tong, S.S., Lowe, M.C., Trush, M.A., Mimmaugh, E.G., Ginsburg, E., Hirokata, Y. and Gram, T.E. 1982. Bronchiolar epithelial damage and impairment of pulmonary microsomal monooxygenase activity in mice by naphthalene. Exp. Mol. Pathol., 37, 358-369.
33. Tomasz, M., Chowdary, D., Lipman, R., Shimotakahara, S., Veiro, D., Walker, V. and Verdine, G.L. 1986. Reaction of DNA with chemically or enzymatically activated mitomycin C: isolation and structure of the major covalent adduct. Proc. Natl. Acad. Sci. U. S. A., 83, 6702-6706.
34. Watanabe, F., Nakano, Y., Saido, H., Tamura, Y. and Yamanaka, H. 1992. NADPH-cytochrome c (P-450) reductase has the activity of NADPH-linked aquacobalamin reductase in rat liver microsomes. Biochim. Biophys. Acta., 1119, 175-177.
35. Wyllie, A.H., Kerr, J.F. and Currie, A.R. 1980. Cell death: the significance of apoptosis. Int. Rev. Cytol., 68, 251-306.
36. Zwaal, R.F. and Schroit, A.J. 1997. Pathophysiologic implications of membrane phospholipid asymmetry in blood cells. Blood, 89, 1121-1132.