The synthetic furanonaphthoquinone induces growth arrest, apoptosis and differentiation in a variety of leukaemias and multiple myeloma cells

British Journal of Haematology

Volumn 131, Issue 4, 2005, Pages 520-529

  Desmond, Julian C ^a,b   Kawabata, Hiroshi ^c   Mueller Tidow, Carsten ^d   Simamura, Eriko ^c   Heber, David ^e   Hirai, Kei Ichi ^c   Phillip Koeffler, H ^b  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b CEDARS SINAI MEDICAL CENTER   (United States)

^c KANAZAWA MEDICAL UNIVERSITY   (Japan)

^d UNIVERSITY OF MÜNSTER   (Germany)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Acute myeloid leukaemia; Apoptosis; Differentiation; Multiple myeloma; Quinone

Indexed keywords

1,4 NAPHTHOQUINONE DERIVATIVE; 2 METHYLNAPHTHO[2,3 B]FURAN 4,9 DIONE; ANTILEUKEMIC AGENT; CALCITRIOL; FNQ 3; RETINOIC ACID; UNCLASSIFIED DRUG; 2 METHYLNAPHTHO(2,3 B)FURAN 4,9 DIONE; 2-METHYLNAPHTHO(2,3-B)FURAN-4,9-DIONE; ANTINEOPLASTIC AGENT; NAPHTHOQUINONE;

ACUTE GRANULOCYTIC LEUKEMIA; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CELL CYCLE ARREST; CELL DIFFERENTIATION; CELL MEMBRANE DEPOLARIZATION; CLONOGENESIS; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; HUMAN; HUMAN CELL; IN VITRO STUDY; INHIBITION KINETICS; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL TOXICITY; MULTIPLE MYELOMA; PRIORITY JOURNAL; TUMOR DIFFERENTIATION; CELL CULTURE; CELL DIVISION; CELL MEMBRANE POTENTIAL; DRUG EFFECT; LEUKEMIA; PATHOLOGY; PHYSIOLOGY;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL DIFFERENTIATION; CELL DIVISION; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; LEUKEMIA; MEMBRANE POTENTIALS; MITOCHONDRIAL MEMBRANES; MULTIPLE MYELOMA; NAPHTHOQUINONES; TUMOR CELLS, CULTURED;

EID: 33644807216     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2005.05803.x     Document Type: Article

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