Simultaneous genotyping of 11 non-synonymous SNPs in the 4 glutathione peroxidase genes using the multiplex single base extension method

Clinica Chimica Acta

Volumn 402, Issue 1-2, 2009, Pages 79-82

  Iida, Reiko ^a   Tsubota, Etsuko ^a   Yuasa, Isao ^b   Takeshita, Haruo ^c   Yasuda, Toshihiro ^a  

^a UNIVERSITY OF FUKUI   (Japan)

^b TOTTORI UNIVERSITY   (Japan)

^c SHIMANE UNIVERSITY   (Japan)

Author keywords

Capillary electrophoresis; Ethnic variation; Genotyping; Glutathione peroxidase; Multiplex single base extension method

Indexed keywords

GLUTATHIONE PEROXIDASE;

ANALYTIC METHOD; ARTICLE; DNA DETERMINATION; ETHNIC GROUP; GENE; GENE MUTATION; GENETIC HETEROGENEITY; GENOTYPE; GERMANY; GPX1 GENE; GPX2 GENE; GPX3 GENE; GPX4 GENE; HUMAN; JAPAN; MULTIPLEX POLYMERASE CHAIN REACTION; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REPRODUCIBILITY; SINGLE NUCLEOTIDE POLYMORPHISM; VALIDATION PROCESS;

GENE FREQUENCY; GENETICS, POPULATION; GENOTYPE; GLUTATHIONE PEROXIDASE; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN ISOFORMS;

EID: 60649117191     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2008.12.027     Document Type: Article

References (15)

1. Halliwell B., and Gutteridge J.M.C. Free radicals in biology and medicine (2007), Oxford University Press Inc, New York
2. Brigelius-Flohé R. Tissue-specific functions of individual glutathione peroxidases. Free Radic Biol Med 27 (1999) 951-965
3. Arthur J.R. The glutathione peroxidases. Cell Mol Life Sci 57 (2000) 1825-1835
4. Brigelius-Flohé R., Müller C., Menard J., Florian S., Schmehl K., and Wingler K. Functions of GI-GPx: lessons from selenium-dependent expression and intracellular localization. Biofactors 14 (2001) 101-106
5. Ratnasinghe D., Tangrea J.A., Andersen M.R., Barrett M.J., Virtamo J., Taylor P.R., et al. Glutathione peroxidase codon 198 polymorphism variant increases lung cancer risk. Cancer Res 60 (2000) 6381-6383
6. Hu Y.J., and Diamond A.M. Role of glutathione peroxidase 1 in breast cancer: loss of heterozygosity and allelic differences in the response to selenium. Cancer Res 63 (2003) 3347-3351
7. Maiorino M., Bosello V., Ursini F., Foresta C., Garolla A., Scapin M., et al. Genetic variations of gpx-4 and male infertility in humans. Biol Reprod 68 (2003) 1134-1141
8. Hamanishi T., Furuta H., Kato H., Doi A., Tamai M., Shimomura H., et al. Functional variants in the glutathione peroxidase-1 (GPx-1) gene are associated with increased intima-media thickness of carotid arteries and risk of macrovascular diseases in Japanese type 2 diabetic patients. Diabetes 53 (2004) 2455-2460
9. Ravn-Haren G., Olsen A., Tjønneland A., Dragsted L.O., Nexø B.A., Wallin H., et al. Associations between GPX1 Pro198Leu polymorphism, erythrocyte GPX activity, alcohol consumption and breast cancer risk in a prospective cohort study. Carcinogenesis 27 (2006) 820-825
10. Iida R., Tsubota E., Takeshita H., and Yasuda T. Multiplex single base extension method for simultaneous genotyping of non-synonymous SNPs in the three human SOD genes. Electrophoresis 29 (2008) 4788-4794
11. Sambrook J., and Russell D.W. Molecular cloning. third ed. (2001), Cold Spring Harbor, New York 5.51-5.54
12. McBride O.W., Mitchell A., Lee B.J., Mullenbach G., and Hatfield D. Gene for selenium-dependent glutathione peroxidase maps to human chromosomes 3, 21 and X. Biofactors 1 (1988) 285-292
13. Diamond A.M., Cruz R., Bencsics C., and Hatfield D. A pseudogene for human glutathione peroxidase. Gene 122 (1992) 377-380
14. Blankenberg S., Rupprecht H.J., Bickel C., Torzewski M., Hafner G., Tiret L., et al. Glutathione peroxidase 1 activity and cardiovascular events in patients with coronary artery disease. N Engl J Med 349 (2003) 1605-1613
15. Forgione M.A., Cap A., Liao R., Moldovan N.I., Eberhardt R.T., Lim C.C., et al. Heterozygous cellular glutathione peroxidase deficiency in the mouse: abnormalities in vascular and cardiac function and structure. Circulation 106 (2002) 1154-1158