Aspirin and indomethacin reduce lung inflammation of mice exposed to cigarette smoke

Biochemical Pharmacology

Volumn 77, Issue 6, 2009, Pages 1029-1039

  Castro, Paulo ^a   Nasser, Helena ^a   Abrahão, Agessandro ^a   dos Reis, Larissa Cardilo ^a   Riça, Ingred ^a   Valença, Samuel S ^b   Rezende, Daniele C ^a   Quintas, Luis E M ^a   Cavalcante, Moisés C Marinho ^a   Porto, Luis Cristóvão ^b   Koatz, Vera Lucia G ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Aspirin; Cigarette smoke; Indomethacin; Lung inflammation; NF B; p38 MAP kinase

Indexed keywords

ACETYLSALICYLIC ACID; CIGARETTE SMOKE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDOMETACIN; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; C57BL 6 MOUSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; LIPID PEROXIDATION; LUNG LAVAGE; MALE; MOUSE; NEUTROPHILIA; NONHUMAN; OXIDATIVE STRESS; PNEUMONIA; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ANIMALS; ASPIRIN; BRONCHOALVEOLAR LAVAGE FLUID; DOSE-RESPONSE RELATIONSHIP, DRUG; INDOMETHACIN; MALE; MICE; MICE, INBRED C57BL; NEUTROPHIL INFILTRATION; OXIDATIVE STRESS; PNEUMONIA; SMOKE; TOBACCO;

EID: 60649100616     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2008.12.012     Document Type: Article

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