Activation and inactivation of cyclo-oxygenase in rat alveolar macrophages by aqueous cigarette tar extracts

Free Radical Biology and Medicine

Volumn 27, Issue 5-6, 1999, Pages 673-682

  Hwang, Daniel ^a   Chanmugam, Prithiva ^a   Boudreau, Mary ^a   Sohn, Kyung H ^a   Stone, Koni ^b   Pryor, William A ^b  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

^b LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

Aqueous cigarette tar extracts; Arachidonic acid; Free radicals; p38 (MAPK) phosphorylation; Prostaglandins; Vitamin E

Indexed keywords

ARACHIDONIC ACID; CIGARETTE SMOKE; CIGARETTE SMOKE CONDENSATE; FREE RADICAL; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE;

ALPHA TOCOPHEROL DEFICIENCY; ANIMAL CELL; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INACTIVATION; FEMALE; LUNG ALVEOLUS MACROPHAGE; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; RAT;

ANIMALS; ARACHIDONIC ACID; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL SURVIVAL; CYCLOOXYGENASE 1; DINOPROSTONE; ENZYME ACTIVATION; FEMALE; HUMANS; ISOENZYMES; MACROPHAGES, ALVEOLAR; MEMBRANE PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PLANTS, TOXIC; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SMOKING; TARS; TOBACCO; TRYPAN BLUE; VITAMIN E DEFICIENCY;

EID: 0032817971     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(99)00120-3     Document Type: Article

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