Inhibition of glucose metabolism sensitizes tumor cells to death receptor-triggered apoptosis through enhancement of death-inducing signaling complex formation and apical procaspase-8 processing

Journal of Biological Chemistry

Volumn 278, Issue 15, 2003, Pages 12759-12768

  Muñoz Pinedo, Cristina ^a   Ruiz Ruiz, Carmen ^c   De Almodóvar, Carmen Ruiz ^c   Palacios, Carmen ^c   López Rivas, Abelardo ^b  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^b INSTITUTO DE PARASITOLOGÍA Y BIOMEDICINA LÓPEZ NEYRA   (Spain)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; GLUCOSE; TUMORS;

GLYCOLYSIS;

BIOCHEMISTRY;

CASPASE 8; DEOXYGLUCOSE; FAS ANTIBODY; GLUCOSE; PROCASPASE 8; PROTEIN BCL 2; PYRUVIC ACID; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATE; APOPTOSIS REGULATORY PROTEIN; CASP8 PROTEIN, HUMAN; CASP9 PROTEIN, HUMAN; CASPASE; CASPASE 9; CYTOCHROME C; ENZYME PRECURSOR; FAS ANTIGEN; MEMBRANE PROTEIN; PYRUVIC ACID DERIVATIVE; TNFSF10 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; CELL DEATH; CELL KILLING; COMPLEX FORMATION; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME RELEASE; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; IMMUNE SYSTEM; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR CELL; BREAST TUMOR; CELL CULTURE; CELL STRAIN U937; DRUG ANTAGONISM; DRUG EFFECT; FEMALE; HELA CELL; KINETICS; LYMPHOMA; METABOLISM; MITOCHONDRION; PHYSIOLOGY; PROTEIN PROCESSING;

MINK CELL FOCUS-FORMING VIRUS;

ADENOSINE TRIPHOSPHATE; ANTIGENS, CD95; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BREAST NEOPLASMS; CASPASE 8; CASPASE 9; CASPASES; CYTOCHROME C GROUP; DEOXYGLUCOSE; ENZYME ACTIVATION; ENZYME PRECURSORS; FEMALE; GLUCOSE; HELA CELLS; HUMANS; KINETICS; LYMPHOMA; MEMBRANE GLYCOPROTEINS; MITOCHONDRIA; PROTEIN PROCESSING, POST-TRANSLATIONAL; PYRUVATES; SIGNAL TRANSDUCTION; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA; U937 CELLS;

EID: 0037631325     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M212392200     Document Type: Article

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