RNA interference targeting the ACE gene reduced blood pressure and improved myocardial remodelling in SHRs

Clinical Science

Volumn 116, Issue 3, 2009, Pages 249-255

  He, Junhua ^a   Bian, Yunfei ^a   Gao, Fen ^a   Li, Maolian ^a   Qiu, Ling ^a   Wu, Weidong ^a   Zhou, Hua ^a   Liu, Gaizhen ^a   Xiao, Chuanshi ^a  

^a SHANXI MEDICAL UNIVERSITY   (China)

Author keywords

Angiotensin converting enzyme (ACE); Hypertension; Rat; RNA interference

Indexed keywords

ADENOVIRUS VECTOR; ANGIOTENSIN II; DIPEPTIDYL CARBOXYPEPTIDASE; ENHANCED GREEN FLUORESCENT PROTEIN; MESSENGER RNA; SHORT HAIRPIN RNA; SODIUM CHLORIDE; SMALL INTERFERING RNA;

ANGIOTENSIN BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; ENZYME BLOOD LEVEL; GENE EXPRESSION REGULATION; GENE SILENCING; GENE TARGETING; HEART LEFT VENTRICLE MASS; HEART VENTRICLE HYPERTROPHY; HEART WEIGHT; HYPERTENSION; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; RNA INTERFERENCE; SPONTANEOUSLY HYPERTENSIVE RAT; SYSTOLIC BLOOD PRESSURE; ADENOVIRUS; ANIMAL; BIOSYNTHESIS; BLOOD; BLOOD PRESSURE; BODY WEIGHT; EVALUATION; GENE THERAPY; GENE VECTOR; GENETICS; HEART MUSCLE; HEART VENTRICLE REMODELING; METABOLISM; METHODOLOGY; ORGAN SIZE; PATHOLOGY; PATHOPHYSIOLOGY;

ADENOVIRIDAE; ANIMALS; BLOOD PRESSURE; BODY WEIGHT; GENE TARGETING; GENE THERAPY; GENETIC VECTORS; HYPERTENSION; MALE; MYOCARDIUM; ORGAN SIZE; PEPTIDYL-DIPEPTIDASE A; RATS; RATS, INBRED SHR; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; VENTRICULAR REMODELING;

EID: 60549089582     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20080048     Document Type: Article

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