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Volumn 320, Issue , 2008, Pages 1-19

RNA interference in mammalian cell systems

Author keywords

[No Author keywords available]

Indexed keywords

ARGONAUTE PROTEIN; DICER; DOUBLE STRANDED RNA; INITIATION FACTOR; RIBONUCLEASE III;

EID: 40649125064     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-540-75157-1_1     Document Type: Review
Times cited : (23)

References (131)
  • 3
    • 0141750434 scopus 로고    scopus 로고
    • Identification of modulators of TRAIL-induced apoptosis via RNAi-based phenotypic screening
    • Aza-Blanc P, Cooper CL, Wagner K, Batalov S, Deveraux QL, Cooke MP (2003) Identification of modulators of TRAIL-induced apoptosis via RNAi-based phenotypic screening. Mol Cell 12:627-637
    • (2003) Mol Cell , vol.12 , pp. 627-637
    • Aza-Blanc, P.1    Cooper, C.L.2    Wagner, K.3    Batalov, S.4    Deveraux, Q.L.5    Cooke, M.P.6
  • 4
    • 23944468103 scopus 로고    scopus 로고
    • Genome-wide RNAi analysis of JAK/STAT signaling components in Drosophila
    • Baeg GH, Zhou R, Perrimon N (2005) Genome-wide RNAi analysis of JAK/STAT signaling components in Drosophila. Genes Dev 19:1861-1870
    • (2005) Genes Dev , vol.19 , pp. 1861-1870
    • Baeg, G.H.1    Zhou, R.2    Perrimon, N.3
  • 5
    • 0020987925 scopus 로고
    • Mechanisms of antiviral action of interferon
    • Baglioni C, Nilsen TW (1983) Mechanisms of antiviral action of interferon. Interferon 5:23-42
    • (1983) Interferon , vol.5 , pp. 23-42
    • Baglioni, C.1    Nilsen, T.W.2
  • 7
    • 0037069417 scopus 로고    scopus 로고
    • Retroviral delivery of small interfering RNA into primary cells
    • Barton GM, Medzhitov R (2002) Retroviral delivery of small interfering RNA into primary cells. Proc Natl Acad Sci U S A 99:14943-14945
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 14943-14945
    • Barton, G.M.1    Medzhitov, R.2
  • 10
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA interference
    • Bernstein E, Caudy AA, Hammond SM, Hannon GJ (2001a) Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409:363-366
    • (2001) Nature , vol.409 , pp. 363-366
    • Bernstein, E.1    Caudy, A.A.2    Hammond, S.M.3    Hannon, G.J.4
  • 12
    • 0035807818 scopus 로고    scopus 로고
    • Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines
    • Billy E, Brondani V, Zhang H, Muller U, Filipowicz W (2001) Specific interference with gene expression induced by long, double-stranded RNA in mouse embryonal teratocarcinoma cell lines. Proc Natl Acad Sci U S A 98:14428-14433
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 14428-14433
    • Billy, E.1    Brondani, V.2    Zhang, H.3    Muller, U.4    Filipowicz, W.5
  • 14
    • 0035940494 scopus 로고    scopus 로고
    • A genome-wide screen in Saccharomyces cerevisiae for genes affecting UV radiation sensitivity
    • Birrell GW, Giaever G, Chu AM, Davis RW, Brown JM (2001) A genome-wide screen in Saccharomyces cerevisiae for genes affecting UV radiation sensitivity. Proc Natl Acad Sci U S A 98:12608-12613
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 12608-12613
    • Birrell, G.W.1    Giaever, G.2    Chu, A.M.3    Davis, R.W.4    Brown, J.M.5
  • 15
    • 13444262170 scopus 로고    scopus 로고
    • Inhibition of respiratory viruses by nasally administered siRNA
    • Bitko V, Musiyenko A, Shulyayeva O, Barik S (2005) Inhibition of respiratory viruses by nasally administered siRNA. Nat Med 11:50-55
    • (2005) Nat Med , vol.11 , pp. 50-55
    • Bitko, V.1    Musiyenko, A.2    Shulyayeva, O.3    Barik, S.4
  • 16
    • 1642499415 scopus 로고    scopus 로고
    • Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs
    • Bohnsack MT, Czaplinski K, Gorlich D (2004) Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs. RNA 10:185-191
    • (2004) RNA , vol.10 , pp. 185-191
    • Bohnsack, M.T.1    Czaplinski, K.2    Gorlich, D.3
  • 18
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • Brummelkamp TR, Bernards R, Agami R (2002a) A system for stable expression of short interfering RNAs in mammalian cells. Science 296:550-553
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 19
    • 0036726313 scopus 로고    scopus 로고
    • Stable suppression of tumorigenicity by virus-mediated RNA interference
    • Brummelkamp TR, Bernards R, Agami R (2002b) Stable suppression of tumorigenicity by virus-mediated RNA interference. Cancer Cell 2:243-247
    • (2002) Cancer Cell , vol.2 , pp. 243-247
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 20
    • 0035859929 scopus 로고    scopus 로고
    • Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
    • Caplen NJ, Parrish S, Imani F, Fire A, Morgan RA (2001) Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems. Proc Natl Acad Sci U S A 98:9742-9747
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 9742-9747
    • Caplen, N.J.1    Parrish, S.2    Imani, F.3    Fire, A.4    Morgan, R.A.5
  • 21
    • 1442360415 scopus 로고    scopus 로고
    • RNase III enzymes and the initiation of gene silencing
    • Carmell MA, Hannon GJ (2004) RNase III enzymes and the initiation of gene silencing. Nat Struct Mol Biol 11:214-218
    • (2004) Nat Struct Mol Biol , vol.11 , pp. 214-218
    • Carmell, M.A.1    Hannon, G.J.2
  • 22
    • 0036828639 scopus 로고    scopus 로고
    • The Argonaute family: Tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis
    • Carmell MA, Xuan Z, Zhang MQ, Hannon GJ (2002) The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis. Genes Dev 16:2733-2742
    • (2002) Genes Dev , vol.16 , pp. 2733-2742
    • Carmell, M.A.1    Xuan, Z.2    Zhang, M.Q.3    Hannon, G.J.4
  • 24
    • 16244377103 scopus 로고    scopus 로고
    • A crucial test
    • Check E (2005) A crucial test. Nat Med 11:243-244
    • (2005) Nat Med , vol.11 , pp. 243-244
    • Check, E.1
  • 25
    • 18244400410 scopus 로고    scopus 로고
    • Functional genomic analysis of the Wntwingless signaling pathway
    • DasGupta R, Kaykas A, Moon RT, Perrimon N (2005) Functional genomic analysis of the Wntwingless signaling pathway. Science 308:826-833
    • (2005) Science , vol.308 , pp. 826-833
    • DasGupta, R.1    Kaykas, A.2    Moon, R.T.3    Perrimon, N.4
  • 26
    • 0036963990 scopus 로고    scopus 로고
    • Rotavirus gene silencing by small interfering RNAs
    • Dector MA, Romero P, Lopez S, Arias CF (2002) Rotavirus gene silencing by small interfering RNAs. EMBO J 3:1175-1180
    • (2002) EMBO J , vol.3 , pp. 1175-1180
    • Dector, M.A.1    Romero, P.2    Lopez, S.3    Arias, C.F.4
  • 31
    • 0034312298 scopus 로고    scopus 로고
    • The plasma membrane as a combat zone in the HIV battlefield
    • Doms RW, Trono D (2000) The plasma membrane as a combat zone in the HIV battlefield. Genes Dev 14:2677-2688
    • (2000) Genes Dev , vol.14 , pp. 2677-2688
    • Doms, R.W.1    Trono, D.2
  • 33
    • 0013889480 scopus 로고
    • Morphogenesis of bacteriophage T4 in extracts of mutant-infected cells
    • Edgar R, Wood W (1966) Morphogenesis of bacteriophage T4 in extracts of mutant-infected cells. Proc Natl Acad Sci U S A 55:498-505
    • (1966) Proc Natl Acad Sci U S A , vol.55 , pp. 498-505
    • Edgar, R.1    Wood, W.2
  • 34
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T (2001) Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411:494-498
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 35
    • 0034615578 scopus 로고    scopus 로고
    • A novel type of RNase III family proteins in eukaryotes
    • Filippov V, Solovyev V, Filippova M, Gill SS (2000) A novel type of RNase III family proteins in eukaryotes. Gene 245:213-221
    • (2000) Gene , vol.245 , pp. 213-221
    • Filippov, V.1    Solovyev, V.2    Filippova, M.3    Gill, S.S.4
  • 36
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC (1998) Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391:806-811
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 37
    • 0141860062 scopus 로고    scopus 로고
    • Mouse ribonuclease III. cDNA structure, expression analysis, and chromosomal location
    • Fortin KR, Nicholson RH, Nicholson AW (2002) Mouse ribonuclease III. cDNA structure, expression analysis, and chromosomal location. BMC Genomics 3:26
    • (2002) BMC Genomics , vol.3 , pp. 26
    • Fortin, K.R.1    Nicholson, R.H.2    Nicholson, A.W.3
  • 39
    • 33750887331 scopus 로고    scopus 로고
    • A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling
    • Friedman A, Perrimon N (2006) A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling. Nature 444:230-234
    • (2006) Nature , vol.444 , pp. 230-234
    • Friedman, A.1    Perrimon, N.2
  • 40
    • 0037418322 scopus 로고    scopus 로고
    • RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription
    • Ge Q, McManus MT, Nguyen T, Shen CH, Sharp PA, Eisen HN, Chen J (2003) RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription. Proc Natl Acad Sci U S A 100:2718-2723
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 2718-2723
    • Ge, Q.1    McManus, M.T.2    Nguyen, T.3    Shen, C.H.4    Sharp, P.A.5    Eisen, H.N.6    Chen, J.7
  • 41
    • 0037173615 scopus 로고    scopus 로고
    • Giaever G, Chu AM, Ni L, Connelly C, Riles L, Veronneau S, Dow S, Lucau-Danila A, Anderson K, Andre B, Arkin AP, Astromoff A, El-Bakkoury M, Bangham R, Benito R, Brachat S, Campanaro S, Curtiss M, Davis K, Deutschbauer A, Entian KD, Flaherty P, Foury F, Garfinkel DJ, Gerstein M, Gotte D, Guldener U, Hegemann JH, Hempel S, Herman Z, Jaramillo DF, Kelly DE, Kelly SL, Kotter P, LaBonte D, Lamb DC, Lan N, Liang H, Liao H, Liu L, Luo C, Lussier M, Mao R, Menard P, Ooi SL, Revuelta JL, Roberts CJ, Rose M, Ross-Macdonald P, Scherens B, Schimmack G, Shafer B, Shoemaker DD, Sookhai-Mahadeo S, Storms RK, Strathern JN, Valle G, Voet M, Volckaert G, Wang CY, Ward TR, Wilhelmy J, Winzeler EA, Yang Y, Yen G, Youngman E, Yu K, Bussey H, Boeke JD, Snyder M, Philippsen P, Davis RW, Johnston M (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418:387-391
    • Giaever G, Chu AM, Ni L, Connelly C, Riles L, Veronneau S, Dow S, Lucau-Danila A, Anderson K, Andre B, Arkin AP, Astromoff A, El-Bakkoury M, Bangham R, Benito R, Brachat S, Campanaro S, Curtiss M, Davis K, Deutschbauer A, Entian KD, Flaherty P, Foury F, Garfinkel DJ, Gerstein M, Gotte D, Guldener U, Hegemann JH, Hempel S, Herman Z, Jaramillo DF, Kelly DE, Kelly SL, Kotter P, LaBonte D, Lamb DC, Lan N, Liang H, Liao H, Liu L, Luo C, Lussier M, Mao R, Menard P, Ooi SL, Revuelta JL, Roberts CJ, Rose M, Ross-Macdonald P, Scherens B, Schimmack G, Shafer B, Shoemaker DD, Sookhai-Mahadeo S, Storms RK, Strathern JN, Valle G, Voet M, Volckaert G, Wang CY, Ward TR, Wilhelmy J, Winzeler EA, Yang Y, Yen G, Youngman E, Yu K, Bussey H, Boeke JD, Snyder M, Philippsen P, Davis RW, Johnston M (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418:387-391
  • 42
    • 0034084338 scopus 로고    scopus 로고
    • Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): Mechanism of action
    • Gil J, Esteban M (2000) Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): mechanism of action. Apoptosis 5:107-114
    • (2000) Apoptosis , vol.5 , pp. 107-114
    • Gil, J.1    Esteban, M.2
  • 45
    • 17844364875 scopus 로고    scopus 로고
    • Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing
    • Grishok A, Pasquinelli AE, Conte D, Li N, Parrish S, Ha I, Baillie DL, Fire A, Ruvkun G, Mello CC (2001) Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 106:23-34
    • (2001) Cell , vol.106 , pp. 23-34
    • Grishok, A.1    Pasquinelli, A.E.2    Conte, D.3    Li, N.4    Parrish, S.5    Ha, I.6    Baillie, D.L.7    Fire, A.8    Ruvkun, G.9    Mello, C.C.10
  • 46
    • 0029801668 scopus 로고    scopus 로고
    • A bulged lin-4/lin-14 RNA duplex is sufficient for Caenorhabditis elegans lin-14 temporal gradient formation
    • Ha I, Wightman B, Ruvkun G (1996) A bulged lin-4/lin-14 RNA duplex is sufficient for Caenorhabditis elegans lin-14 temporal gradient formation. Genes Dev 10:3041-3050
    • (1996) Genes Dev , vol.10 , pp. 3041-3050
    • Ha, I.1    Wightman, B.2    Ruvkun, G.3
  • 47
    • 3042602447 scopus 로고    scopus 로고
    • Kinetic analysis of the RNAi enzyme complex
    • Haley B, Zamore PD (2004) Kinetic analysis of the RNAi enzyme complex. Nat Struct Mol Biol 11:599-606
    • (2004) Nat Struct Mol Biol , vol.11 , pp. 599-606
    • Haley, B.1    Zamore, P.D.2
  • 49
    • 0034673638 scopus 로고    scopus 로고
    • An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
    • Hammond SM, Bernstein E, Beach D, Hannon GJ (2000) An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature 404:293-296
    • (2000) Nature , vol.404 , pp. 293-296
    • Hammond, S.M.1    Bernstein, E.2    Beach, D.3    Hannon, G.J.4
  • 50
    • 10644234841 scopus 로고    scopus 로고
    • The Drosha-DGCR8 complex in primary microRNA processing
    • Han J, Lee Y, Yeom KH, Kim YK, Jin H, Kim VN (2004) The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev 18:3016-3027
    • (2004) Genes Dev , vol.18 , pp. 3016-3027
    • Han, J.1    Lee, Y.2    Yeom, K.H.3    Kim, Y.K.4    Jin, H.5    Kim, V.N.6
  • 52
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • Hannon GJ (2002) RNA interference. Nature 418:244-251
    • (2002) Nature , vol.418 , pp. 244-251
    • Hannon, G.J.1
  • 53
    • 0024425887 scopus 로고
    • Checkpoints: Controls that ensure the order of cell cycle events
    • Hartwell LH, Weinert TA (1989) Checkpoints: controls that ensure the order of cell cycle events. Science 246:629-634
    • (1989) Science , vol.246 , pp. 629-634
    • Hartwell, L.H.1    Weinert, T.A.2
  • 56
    • 0035800521 scopus 로고    scopus 로고
    • A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
    • Hutvagner G, McLachlan J, Pasquinelli AE, Balint E, Tuschl T, Zamore PD (2001) A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 293:834-838
    • (2001) Science , vol.293 , pp. 834-838
    • Hutvagner, G.1    McLachlan, J.2    Pasquinelli, A.E.3    Balint, E.4    Tuschl, T.5    Zamore, P.D.6
  • 59
    • 0037173610 scopus 로고    scopus 로고
    • Modulation of HIV-1 replication by RNA interference
    • Jacque JM, Triques K, Stevenson M (2002) Modulation of HIV-1 replication by RNA interference. Nature 418:435-438
    • (2002) Nature , vol.418 , pp. 435-438
    • Jacque, J.M.1    Triques, K.2    Stevenson, M.3
  • 60
    • 0037372313 scopus 로고    scopus 로고
    • Inhibition of gammaherpesvirus replication by RNA interference
    • Jia Q, Sun R (2003) Inhibition of gammaherpesvirus replication by RNA interference. J Virol 77:3301-3306
    • (2003) J Virol , vol.77 , pp. 3301-3306
    • Jia, Q.1    Sun, R.2
  • 61
    • 0037452625 scopus 로고    scopus 로고
    • Interference of hepatitis C virus RNA replication by short interfering RNAs
    • Kapadia SB, Brideau-Andersen A, Chisari FV (2003) Interference of hepatitis C virus RNA replication by short interfering RNAs. Proc Natl Acad Sci U S A 100:2014-2018
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 2014-2018
    • Kapadia, S.B.1    Brideau-Andersen, A.2    Chisari, F.V.3
  • 62
    • 0035887005 scopus 로고    scopus 로고
    • Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
    • Ketting RF, Fischer SE, Bernstein E, Sijen T, Hannon GJ, Plasterk RH (2001) Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev 15:2654-2659
    • (2001) Genes Dev , vol.15 , pp. 2654-2659
    • Ketting, R.F.1    Fischer, S.E.2    Bernstein, E.3    Sijen, T.4    Hannon, G.J.5    Plasterk, R.H.6
  • 64
    • 0035929322 scopus 로고    scopus 로고
    • A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans
    • Knight SW, Bass BL (2001) A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans. Science 293:2269-2271
    • (2001) Science , vol.293 , pp. 2269-2271
    • Knight, S.W.1    Bass, B.L.2
  • 65
    • 4344637081 scopus 로고    scopus 로고
    • Arabidopsis micro-RNA biogenesis through Dicer-like 1 protein functions
    • Kurihara Y, Watanabe Y (2004) Arabidopsis micro-RNA biogenesis through Dicer-like 1 protein functions. Proc Natl Acad Sci U S A 101:12753-12758
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 12753-12758
    • Kurihara, Y.1    Watanabe, Y.2
  • 66
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed RNAs
    • Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T (2001) Identification of novel genes coding for small expressed RNAs. Science 294:853-858
    • (2001) Science , vol.294 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 68
    • 10344248903 scopus 로고    scopus 로고
    • The human DiGeorge syndrome critical region gene 8 and its D. melanogaster homolog are required for miRNA biogenesis
    • Landthaler M, Yalcin A, Tuschl T (2004) The human DiGeorge syndrome critical region gene 8 and its D. melanogaster homolog are required for miRNA biogenesis. Curr Biol 14:2162-2167
    • (2004) Curr Biol , vol.14 , pp. 2162-2167
    • Landthaler, M.1    Yalcin, A.2    Tuschl, T.3
  • 69
    • 0035955361 scopus 로고    scopus 로고
    • An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    • Lau NC, Lim LP, Weinstein EG, Bartel DP (2001) An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 294:858-862
    • (2001) Science , vol.294 , pp. 858-862
    • Lau, N.C.1    Lim, L.P.2    Weinstein, E.G.3    Bartel, D.P.4
  • 71
    • 0035955366 scopus 로고    scopus 로고
    • An extensive class of small RNAs in Caenorhabditis elegans
    • Lee RC, Ambros V (2001) An extensive class of small RNAs in Caenorhabditis elegans. Science 294:862-864
    • (2001) Science , vol.294 , pp. 862-864
    • Lee, R.C.1    Ambros, V.2
  • 72
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee RC, Feinbaum RL, Ambros V (1993) The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75:843-854
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 73
    • 0037228016 scopus 로고    scopus 로고
    • A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity
    • Lee SS, Lee RY, Fraser AG, Kamath RS, Ahringer J, Ruvkun G (2003a) A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity. Nat Genet 33:40-48
    • (2003) Nat Genet , vol.33 , pp. 40-48
    • Lee, S.S.1    Lee, R.Y.2    Fraser, A.G.3    Kamath, R.S.4    Ahringer, J.5    Ruvkun, G.6
  • 77
    • 20444419344 scopus 로고    scopus 로고
    • Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance
    • MacKeigan JP, Murphy LO, Blenis J (2005) Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance. Nat Cell Biol 7:591-600
    • (2005) Nat Cell Biol , vol.7 , pp. 591-600
    • MacKeigan, J.P.1    Murphy, L.O.2    Blenis, J.3
  • 82
    • 0036245628 scopus 로고    scopus 로고
    • U6 promoter driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells
    • Miyagishi M, Taira K (2002) U6 promoter driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells. Nat Biotechnol 20:497-500
    • (2002) Nat Biotechnol , vol.20 , pp. 497-500
    • Miyagishi, M.1    Taira, K.2
  • 85
    • 28444451148 scopus 로고    scopus 로고
    • A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway
    • Nybakken K, Vokes SA, Lin TY, McMahon AP, Perrimon N (2005) A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway. Nat Genet 37:1323-1332
    • (2005) Nat Genet , vol.37 , pp. 1323-1332
    • Nybakken, K.1    Vokes, S.A.2    Lin, T.Y.3    McMahon, A.P.4    Perrimon, N.5
  • 86
    • 0035798415 scopus 로고    scopus 로고
    • ATP requirements and small interfering RNA structure in the RNA interference pathway
    • Nykanen A, Haley B, Zamore PD (2001) ATP requirements and small interfering RNA structure in the RNA interference pathway. Cell 107:309-321
    • (2001) Cell , vol.107 , pp. 309-321
    • Nykanen, A.1    Haley, B.2    Zamore, P.D.3
  • 87
    • 0036653097 scopus 로고    scopus 로고
    • RNA interference: The new somatic cell genetics?
    • Paddison PJ, Hannon GJ (2002) RNA interference: the new somatic cell genetics? Cancer Cell 2:17-23
    • (2002) Cancer Cell , vol.2 , pp. 17-23
    • Paddison, P.J.1    Hannon, G.J.2
  • 88
    • 0037022382 scopus 로고    scopus 로고
    • Stable suppression of gene expression in mammalian cells by RNAi
    • Paddison PJ, Caudy AA, Hannon GJ (2002a) Stable suppression of gene expression in mammalian cells by RNAi. Proc Natl Acad Sci U S A 99:1443-1448
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 1443-1448
    • Paddison, P.J.1    Caudy, A.A.2    Hannon, G.J.3
  • 89
    • 0037089589 scopus 로고    scopus 로고
    • Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
    • Paddison PJ, Caudy AA, Bernstein E, Hannon GJ, Conklin DS (2002b) Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev 16:948-958
    • (2002) Genes Dev , vol.16 , pp. 948-958
    • Paddison, P.J.1    Caudy, A.A.2    Bernstein, E.3    Hannon, G.J.4    Conklin, D.S.5
  • 93
    • 0036251639 scopus 로고    scopus 로고
    • Effective expression of small interfering RNA in human cells
    • Paul CP, Good PD, Winer I, Engelke DR (2002) Effective expression of small interfering RNA in human cells. Nat Biotechnol 20:505-508
    • (2002) Nat Biotechnol , vol.20 , pp. 505-508
    • Paul, C.P.1    Good, P.D.2    Winer, I.3    Engelke, D.R.4
  • 95
    • 0037422583 scopus 로고    scopus 로고
    • Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5
    • Qin XF, An DS, Chen IS, Baltimore D (2003) Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5. Proc Natl Acad Sci U S A 100:183-188
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 183-188
    • Qin, X.F.1    An, D.S.2    Chen, I.S.3    Baltimore, D.4
  • 96
    • 0037422607 scopus 로고    scopus 로고
    • Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs
    • Randall G, Grakoui A, Rice CM (2003) Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs. Proc Natl Acad Sci U S A 100:235-240
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 235-240
    • Randall, G.1    Grakoui, A.2    Rice, C.M.3
  • 97
    • 33645165026 scopus 로고    scopus 로고
    • Viral-based modeling and correction of neurodegenerative diseases by RNA interference
    • Raoul C, Barker SD, Aebischer P (2006) Viral-based modeling and correction of neurodegenerative diseases by RNA interference. Gene Ther 13:487-495
    • (2006) Gene Ther , vol.13 , pp. 487-495
    • Raoul, C.1    Barker, S.D.2    Aebischer, P.3
  • 99
    • 33646848909 scopus 로고    scopus 로고
    • RNAi as a treatment for HIV-1 infection
    • Rossi JJ (2006) RNAi as a treatment for HIV-1 infection. Biotechniques 40:s25-s29
    • (2006) Biotechniques , vol.40
    • Rossi, J.J.1
  • 101
    • 0036752955 scopus 로고    scopus 로고
    • Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways
    • Schwarz DS, Hutvagner G, Haley B, Zamore PD (2002) Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways. Mol Cell 10:537-548
    • (2002) Mol Cell , vol.10 , pp. 537-548
    • Schwarz, D.S.1    Hutvagner, G.2    Haley, B.3    Zamore, P.D.4
  • 106
    • 0033634943 scopus 로고    scopus 로고
    • The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor
    • Slack FJ, Basson M, Liu Z, Ambros V, Horvitz HR, Ruvkun G (2000) The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. Mol Cell 5:659-669
    • (2000) Mol Cell , vol.5 , pp. 659-669
    • Slack, F.J.1    Basson, M.2    Liu, Z.3    Ambros, V.4    Horvitz, H.R.5    Ruvkun, G.6
  • 109
    • 4444302947 scopus 로고    scopus 로고
    • Crystal structure of Argonaute and its implications for RISC slicer activity
    • Song JJ, Smith SK, Hannon GJ, Joshua-Tor L (2004) Crystal structure of Argonaute and its implications for RISC slicer activity. Science 305:1434-1437
    • (2004) Science , vol.305 , pp. 1434-1437
    • Song, J.J.1    Smith, S.K.2    Hannon, G.J.3    Joshua-Tor, L.4
  • 110
    • 24944560377 scopus 로고    scopus 로고
    • A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells
    • Stegmeier F, Hu G, Rickles RJ, Hannon GJ, Elledge SJ (2005) A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells. Proc Natl Acad Sci U S A 102:13212-13217
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 13212-13217
    • Stegmeier, F.1    Hu, G.2    Rickles, R.J.3    Hannon, G.J.4    Elledge, S.J.5
  • 111
    • 0037322606 scopus 로고    scopus 로고
    • RNAi: Mammalian oocytes do it without RNAdependent RNA polymerase
    • Stein P, Svoboda P, Anger M, Schultz RM (2003) RNAi: mammalian oocytes do it without RNAdependent RNA polymerase. RNA 9:187-192
    • (2003) RNA , vol.9 , pp. 187-192
    • Stein, P.1    Svoboda, P.2    Anger, M.3    Schultz, R.M.4
  • 113
    • 0033766888 scopus 로고    scopus 로고
    • Selective reduction of dormant maternal mRNAs in mouse oocytes by RNA interference
    • Svoboda P, Stein P, Hayashi H, Schultz RM (2000) Selective reduction of dormant maternal mRNAs in mouse oocytes by RNA interference. Development 127:4147-4156
    • (2000) Development , vol.127 , pp. 4147-4156
    • Svoboda, P.1    Stein, P.2    Hayashi, H.3    Schultz, R.M.4
  • 114
    • 0037452812 scopus 로고    scopus 로고
    • A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA
    • Tiscornia G, Singer O, Ikawa M, Verma IM (2003) A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA. Proc Natl Acad Sci U S A 100:1844-1848
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 1844-1848
    • Tiscornia, G.1    Singer, O.2    Ikawa, M.3    Verma, I.M.4
  • 117
    • 33644768174 scopus 로고    scopus 로고
    • Control of translation and mRNA degradation by miRNAs and siRNAs
    • Valencia-Sanchez MA, Liu J, Hannon GJ, Parker R (2006) Control of translation and mRNA degradation by miRNAs and siRNAs. Genes Dev 20:515-524
    • (2006) Genes Dev , vol.20 , pp. 515-524
    • Valencia-Sanchez, M.A.1    Liu, J.2    Hannon, G.J.3    Parker, R.4
  • 118
    • 0037072661 scopus 로고    scopus 로고
    • Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi
    • Volpe TA, Kidner C, Hall IM, Teng G, Grewal SI, Martienssen RA (2002) Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi. Science 297:1833-1837
    • (2002) Science , vol.297 , pp. 1833-1837
    • Volpe, T.A.1    Kidner, C.2    Hall, I.M.3    Teng, G.4    Grewal, S.I.5    Martienssen, R.A.6
  • 120
    • 0033789992 scopus 로고    scopus 로고
    • Specific interference with gene function by double-stranded RNA in early mouse development
    • Wianny F, Zernicka-Goetz M (2000) Specific interference with gene function by double-stranded RNA in early mouse development. Nat Cell Biol 2:70-75
    • (2000) Nat Cell Biol , vol.2 , pp. 70-75
    • Wianny, F.1    Zernicka-Goetz, M.2
  • 121
    • 0027730383 scopus 로고
    • Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
    • Wightman B, Ha I, Ruvkun G (1993) Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 75:855-862
    • (1993) Cell , vol.75 , pp. 855-862
    • Wightman, B.1    Ha, I.2    Ruvkun, G.3
  • 122
    • 0030996469 scopus 로고    scopus 로고
    • Role of the double-stranded RNA-activated protein kinase (PKR) in cell regulation
    • Williams BR (1997) Role of the double-stranded RNA-activated protein kinase (PKR) in cell regulation. Biochem Soc Trans 25:509-513
    • (1997) Biochem Soc Trans , vol.25 , pp. 509-513
    • Williams, B.R.1
  • 123
    • 0033529707 scopus 로고    scopus 로고
    • Winzeler EA, Shoemaker DD, Astromoff A, Liang H, Anderson K, Andre B, Bangham R, Benito R, Boeke JD, Bussey H, Chu AM, Connelly C, Davis K, Dietrich F, Dow SW, El Bakkoury M, Foury F, Friend SH, Gentalen E, Giaever G, Hegemann JH, Jones T, Laub M, Liao H, Liebundguth N, Lockhart DJ, Lucau-Danila A, Lussier M, M'Rabet N, Menard P, Mittmann M, Pai C, Rebischung C, Revuelta JL, Riles L, Roberts CJ, Ross-MacDonald P, Scherens B, Snyder M, Sookhai-Mahadeo S, Storms RK, Veronneau S, Voet M, Volckaert G, Ward TR, Wysocki R, Yen GS, Yu K, Zimmermann K, Philippsen P, Johnston M, Davis RW (1999) Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis. Science 285:901
    • Winzeler EA, Shoemaker DD, Astromoff A, Liang H, Anderson K, Andre B, Bangham R, Benito R, Boeke JD, Bussey H, Chu AM, Connelly C, Davis K, Dietrich F, Dow SW, El Bakkoury M, Foury F, Friend SH, Gentalen E, Giaever G, Hegemann JH, Jones T, Laub M, Liao H, Liebundguth N, Lockhart DJ, Lucau-Danila A, Lussier M, M'Rabet N, Menard P, Mittmann M, Pai C, Rebischung C, Revuelta JL, Riles L, Roberts CJ, Ross-MacDonald P, Scherens B, Snyder M, Sookhai-Mahadeo S, Storms RK, Veronneau S, Voet M, Volckaert G, Ward TR, Wysocki R, Yen GS, Yu K, Zimmermann K, Philippsen P, Johnston M, Davis RW (1999) Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis. Science 285:901
  • 124
    • 0034711308 scopus 로고    scopus 로고
    • Human RNase III is a 160-kDa protein involved in preribosomal RNA processing
    • Wu H, Xu H, Miraglia LJ, Crooke ST (2000) Human RNase III is a 160-kDa protein involved in preribosomal RNA processing. J Biol Chem 275:36957-36965
    • (2000) J Biol Chem , vol.275 , pp. 36957-36965
    • Wu, H.1    Xu, H.2    Miraglia, L.J.3    Crooke, S.T.4
  • 125
    • 0034775750 scopus 로고    scopus 로고
    • Specific double-stranded RNA interference in undifferentiated mouse embryonic stem cells
    • Yang S, Tutton S, Pierce E, Yoon K (2001) Specific double-stranded RNA interference in undifferentiated mouse embryonic stem cells. Mol Cell Biol 21:7807-7816
    • (2001) Mol Cell Biol , vol.21 , pp. 7807-7816
    • Yang, S.1    Tutton, S.2    Pierce, E.3    Yoon, K.4
  • 126
    • 0347361541 scopus 로고    scopus 로고
    • Exportin-5 mediates the nuclear export of premicroRNAs and short hairpin RNAs
    • Yi R, Qin Y, Macara IG, Cullen BR (2003) Exportin-5 mediates the nuclear export of premicroRNAs and short hairpin RNAs. Genes Dev 17:3011-3016
    • (2003) Genes Dev , vol.17 , pp. 3011-3016
    • Yi, R.1    Qin, Y.2    Macara, I.G.3    Cullen, B.R.4
  • 127
    • 0037197914 scopus 로고    scopus 로고
    • RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells
    • Yu JY, DeRuiter SL, Turner DL (2002) RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells. Proc Natl Acad Sci U S A 99:6047-6052
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 6047-6052
    • Yu, J.Y.1    DeRuiter, S.L.2    Turner, D.L.3
  • 128
    • 24644446398 scopus 로고    scopus 로고
    • Ribo-gnome: The big world of small RNAs
    • Zamore PD, Haley B (2005) Ribo-gnome: the big world of small RNAs. Science 309:1519-1524
    • (2005) Science , vol.309 , pp. 1519-1524
    • Zamore, P.D.1    Haley, B.2
  • 129
    • 0034737298 scopus 로고    scopus 로고
    • RNAi: Double-stranded RNA directs the ATPdependent cleavage of mRNA at 21 to 23 nucleotide intervals
    • Zamore PD, Tuschl T, Sharp PA, Bartel DP (2000) RNAi: double-stranded RNA directs the ATPdependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell 101:25-33
    • (2000) Cell , vol.101 , pp. 25-33
    • Zamore, P.D.1    Tuschl, T.2    Sharp, P.A.3    Bartel, D.P.4
  • 130
    • 0036294527 scopus 로고    scopus 로고
    • Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells
    • Zeng Y, Wagner EJ, Cullen BR (2002) Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Mol Cell 9:1327-1333
    • (2002) Mol Cell , vol.9 , pp. 1327-1333
    • Zeng, Y.1    Wagner, E.J.2    Cullen, B.R.3
  • 131
    • 0037474126 scopus 로고    scopus 로고
    • Argonaute4 control of locus-specific siRNA accumulation and DNA and histone methylation
    • Zilberman D, Cao X, Jacobsen SE (2003) Argonaute4 control of locus-specific siRNA accumulation and DNA and histone methylation. Science 299:716-719
    • (2003) Science , vol.299 , pp. 716-719
    • Zilberman, D.1    Cao, X.2    Jacobsen, S.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.