Chronic hypoxia increases inducible NOS-derived nitric oxide in fetal guinea pig hearts

Pediatric Research

Volumn 65, Issue 2, 2009, Pages 188-192

  Thompson, Loren ^a   Dong, Yafeng ^a,b   Evans, Lashauna ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1BETA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; HYPOXIA INDUCIBLE FACTOR 3ALPHA; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; NEURONAL NITRIC OXIDE SYNTHASE; NITRATE; NITRIC OXIDE; NITRITE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; FETUS HEART; FETUS HYPOXIA; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; ENZYME INDUCTION; ENZYME INHIBITORS; FEMALE; FETAL HYPOXIA; GESTATIONAL AGE; GUINEA PIGS; HEART; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LYSINE; MYOCARDIUM; NITRATES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; PREGNANCY; RNA, MESSENGER; UP-REGULATION;

EID: 60449120022     PISSN: 00313998     EISSN: 15300447     Source Type: Journal    
DOI: 10.1203/PDR.0b013e31818d6ad0     Document Type: Article

References (50)

1. Bae S, Xiao Y, Li G, Casiano CA, Zhang L 2003 Effect of maternal chronic hypoxic exposure during gestation on apoptosis in fetal rat heart. Am J Physiol Heart Circ Physiol 285:H983-H990
2. Richardson BS, Bocking AD 1998 Metabolic and circulatory adaptations to chronic hypoxia in the fetus. Comp Biochem Physiol A Mol Integr Physiol 119:717-723
3. Kamitomo M, Alonso JG, Okai T, Longo LD, Gilbert RD 1993 Effects of long-term high altitude hypoxemia on ovine fetal cardiac output and blood flow distribution. Am J Obstet Gynecol 169:701-707
4. Davis LE, Hohimer AR 1991 Hemodynamics and organ blood flow in fetal sheep subjected to chronic anemia. Am J Physiol 261:R1542-R1548
5. Reller MD, Burson MA, Lohr JL, Morton MJ, Thornburg KL 1995 Nitric oxide is an important determinant of coronary flow at rest and during hypoxemic stress in fetal lambs. Am J Physiol 269:H2074-H2081
6. Thompson LP 2003 Effects of chronic hypoxia on fetal coronary responses. High Alt Med Biol 4:215-224
7. Gilbert RD, Pearce WJ, Longo LD 2003 Fetal cardiac and cerebrovascular acclimatization responses to high altitude, long-term hypoxia. High Alt Med Biol 4:203-213
8. Bunn HF, Poyton RO 1996 Oxygen sensing and molecular adaptation to hypoxia. Physiol Rev 76:839-885
9. Moncada S 1992 The L-arginine:nitric oxide pathway. Acta Physiol Scand 145:201-227
10. Balligand JL, Cannon PJ 1997 Nitric oxide synthases and cardiac muscle. Arterioscler Thromb Vasc Biol 17:1846-1858
11. De Belder AJ, Radomski M, Why HJ, Richardson PJ, Bucknall CA, Salas E, Martin JF, Moncada S 1993 Nitric oxide synthase activities in human myocardium. Lancet 341:84-85
12. Kelly RA, Balligand JL, Smith TW 1996 Nitric oxide and cardiac function. Circ Res 79:363-380
13. Grilli A, De Lutiis MA, Patruno A, Speranza L, Cataldi A, Centurione L, Taccardi AA, Di Napoli P, De Caterina R, Barbacane R, Conti P, Felaco M 2003 Effect of chronic hypoxia on inducible nitric oxide synthase expression in rat myocardial tissue. Exp Biol Med (Maywood) 228:935-942
14. Jung F, Palmer LA, Zhou N, Johns RA 2000 Hypoxic regulation of inducible nitric oxide synthase via hypoxia inducible factor-1 in cardiac myocytes. Circ Res 86:319-325
15. Sabbah HN, Sharov VG, Goldstein S 1998 Programmed cell death in the progression of heart failure. Ann Med 30:33-38
16. Grieve DJ, MacCarthy PA, Gall NP, Cave AC, Shah AM 2001 Divergent biological actions of coronary endothelial nitric oxide during progression of cardiac hypertrophy. Hypertension 38:267-273
17. Ferreiro CR, Chagas AC, Carvalho MH, Dantas AP, Jatene MB, Bento De Souza LC, Lemos Da Luz P 2001 Influence of hypoxia on nitric oxide synthase activity and gene expression in children with congenital heart disease. Circulation 103:2272-2276
18. Bredt DS 2003 Nitric oxide signaling specificity-the heart of the problem. J Cell Sci 116:9-15
19. Massion PB, Balligand JL 2003 Modulation of cardiac contraction, relaxation and rate by the endothelial nitric oxide synthase (eNOS): lessons from genetically modified mice. J Physiol 546:63-75
20. Arnet UA, McMillan A, Dinerman JL, Ballermann B, Lowenstein CJ 1996 Regulation of endothelial nitric oxide synthase during hypoxia. J Biol Chem 271:15069-15073
21. Xu XP, Pollock JS, Tanner MA, Myers PR 1995 Hypoxia activates nitric oxide synthase and stimulates nitric oxide production in porcine coronary resistance arteriolar endothelial cells. Cardiovasc Res 30:841-847
22. Xue C, Rengasamy A, LeCras TD, Koberna PA, Dailey GC, Johns RA 1994 Distribution of NOS in normoxic versus hypoxic rat lung: upregulation of NOS by chronic hypoxia. Am J Physiol 267:L667-L678
23. Fitzpatrick CM, Shi Y, Hutchins WC, Su J, Gross GJ, Ostadal B, Tweddell JS, Baker JE 2005 Cardioprotection in chronically hypoxic rabbits persists upon exposure to normoxia: role of nitric oxide synthase and KATP channels. Am J Physiol Heart Circ Physiol 288:H62-H68
24. Shi Y, Pritchard KA Jr, Holman P, Rafiee P, Griffith OW, Kalyanaraman B, Baker JE 2000 Chronic myocardial hypoxia increases nitric oxide synthase and decreases caveolin-3. Free Radic Biol Med 29:695-703
25. Shi Y, Baker JE, Zhang C, Tweddell JS, Su J, Pritchard KA 2002 Chronic hypoxia increases endothelial nitric oxide synthase generation of nitric oxide by increasing heat shock protein 90 association and serine phosphorylation. Circ Res 91:300-306
26. Felaco M, Grilli A, Gorbunov N, Di Napoli P, De Letiis MA, Di Guilio C, Taccardi AA, Barsotti A, Barbacane RC, Reale M, Conti P 2000 Endothelial NOS expression and ischemia-reperfusion in isolated working rat heart from hypoxic and hyperoxic conditions. Biochim Biophys Acta 1524:203-211
27. Dong Y, Thompson LP 2006 Differential expression of endothelial nitric oxide synthase in coronary and cardiac tissue in hypoxic fetal guinea pig hearts. J Soc Gynecol Investig 13:483-490
28. Shaul PW, Wells LB, Horning KM 1993 Acute and prolonged hypoxia attenuate endothelial nitric oxide production in rat pulmonary arteries by different mechanisms. J Cardiovasc Pharmacol 22:819-827
29. Thompson LP, Dong Y 2005 Chronic hypoxia decreases endothelial nitric oxide synthase protein expression in fetal guinea pig hearts. J Soc Gynecol Investig 12:388-395
30. 2 homeostasis by hypoxia-inducible factor 1 alpha. Genes Dev 12:149-162
31. Semenza GL 2000 HIF-1: mediator of physiological and pathophysiological responses to hypoxia. J Appl Physiol 88:1474-1480
32. Wang GL, Semenza GL 1993 General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia. Proc Natl Acad Sci USA 90:4304-4308
33. Freeburg PB, Abrahamson DR 2004 Divergent expression patterns for hypoxia-inducible factor-1β and aryl hydrocarbon receptor nuclear transporter-2 in developing kidney. J Am Soc Nephrol 15:2569-2578
34. Ema M, Taya S, Yokotani N, Sogawa K, Matsuda Y, Fujii-Kuriyama Y 1997 A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1α regulates the VEGF expression and is potentially involved in lung and vascular development. Proc Natl Acad Sci USA 94:4273-4278
35. Heidbreder M, Frohlich F, Johren O, Dendorfer A, Qadri F, Dominiak P 2003 Hypoxia rapidly activates HIF3alpha mRNA expression. FASEB J 17:1541-1543
36. Connor JR, Manning PT, Settle SL, Moore WM, Jerome GM, Webber RK, Tjoeng FS, Currie MG 1995 Suppression of adjuvant-induced arthritis by selective inhibition of inducible nitric oxide synthase. Eur J Pharmacol 273:15-24
37. Bubner B, Baldwin IT 2004 Use of real-time PCR for determining copy number and zygosity in transgenic plants. Plant Cell Rep 23:263-271
38. Natarajan R, Jones DG, Fisher BJ, Wallace TJ, Ghosh S, Fowler AA 2005 Hypoxia inducible factor-1: regulation by nitric oxide in posthypoxic microvascular endothelium. Biochem Cell Biol 83:597-607
39. Nau PN, Van Natta T, Ralphe JC, Teneyck CJ, Bedell AK, Caldarone CA, Segar JL, Scholz TD 2002 Metabolic adaptation of the fetal and postnatal ovine heart: regulatory role of hypoxia-inducible factors and nuclear respiratory factor-1. Pediatr Res 52:269-278
40. Melillo G, Musso T, Sica A, Taylor LS, Cox GW, Varesio L 1995 A hypoxia-response element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter. J Exp Med 182:1683-1693
41. Palmer LA, Semenza GL, Stoler MH, Johns RA 1998 Hypoxia induces type II NOS gene expression in pulmonary artery endothelial cells via HIF-1. Am J Physiol 274:L212-L219
42. Rouet-Benzineb P, Eddahibi S, Raffestin B, Laplace M, Depond S, Adnot S, Crozatier B 1999 Induction of cardiac nitric oxide synthase 2 in rats exposed to chronic hypoxia. J Mol Cell Cardiol 31:1697-1708
43. He T, Ai M, Zhao XH, Xing YQ 2007 Inducible nitric oxide synthase mediates hypoxia-induced hypoxia-inducible factor-1 alpha activation and vascular endothelial growth factor expression in oxygen-induced retinopathy. Pathobiology 74:336-343
44. Andrew PJ, Mayer B 1999 Enzymatic function of nitric oxide synthases. Cardiovasc Res 43:521-531
45. Thompson LP, Aguan K, Pinkas G, Weiner CP 2000 Chronic hypoxia increases the NO contribution of acetylcholine vasodilation of the fetal guinea pig heart. Am J Physiol Regul Integr Comp Physiol 279:R1813-R1820
46. Thornburg KL, Jonker S, Reller MD 2002 Nitric oxide and fetal coronary regulation. J Card Surg 17:307-316
47. Balligand JL, Kelly RA, Marsden PA, Smith TW, Michel T 1993 Control of cardiac muscle cell function by an endogenous nitric oxide signaling system. Proc Natl Acad Sci USA 90:347-351
48. Guo Y, Jones WK, Xuan Y-T, Tang X-L, Bao W, Wu W-J, Han H, Laubach VE, Ping P, Yang Z, Qiu Y, Belli R 1999 The late phase of ischemic preconditioning is abrogated by targeted disruption of the inducible NO synthase gene. Proc Natl Acad Sci USA 96:11507-11512
49. Wang Y, Guo Y, Zhang SX, Wu W-J, Wang J, Bao W, Bolli R 2002 Ischemic preconditioning upregulates inducible nitric oxide synthase in cardiac myocytes. J Mol Cell Cardiol 34:5-15
50. Tornblom SA, Maul H, Klimaviciute A, Garfield RE, Bystrom B, Malmstrom A, Ekman-Ordeberg G 2005 mRNA expression and localization of bNOS, eNOS and iNOS in human cervix at preterm and term labour. Reprod Biol Endocrinol 3:33