메뉴 건너뛰기




Volumn 46, Issue 2, 2009, Pages 98-102

Thrombin peptide (TP508) promotes adipose tissue-derived stem cell proliferation via PI3 kinase/Akt pathway

Author keywords

Proliferating capacity; Stem cells; Wound healing

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; BROXURIDINE; PHOSPHATIDYLINOSITOL 3 KINASE; THROMBIN; TP 508; UNCLASSIFIED DRUG;

EID: 60349083978     PISSN: 10181172     EISSN: None     Source Type: Journal    
DOI: 10.1159/000142727     Document Type: Article
Times cited : (14)

References (35)
  • 1
    • 0031744875 scopus 로고    scopus 로고
    • Proteinase-activated receptors: Novel mechanisms of signaling by serine proteases
    • Dery O, Corvera CU, Steinhoff M, Bunnett NW: Proteinase-activated receptors: novel mechanisms of signaling by serine proteases. Am J Physiol 1998;274:C1429-C1452.
    • (1998) Am J Physiol , vol.274
    • Dery, O.1    Corvera, C.U.2    Steinhoff, M.3    Bunnett, N.W.4
  • 2
    • 0034648757 scopus 로고    scopus 로고
    • Thrombin signalling and protease-activated receptors
    • Coughlin SR: Thrombin signalling and protease-activated receptors. Nature 2000;407:258-264.
    • (2000) Nature , vol.407 , pp. 258-264
    • Coughlin, S.R.1
  • 6
    • 0034608013 scopus 로고    scopus 로고
    • Thrombin responses in human endothelial cells. Contributions from receptors other than PAR1 include the transactivation of PAR2 by thrombin-cleaved PAR1
    • O'Brien PJ, Prevost N, Molino M, Hollinger MK, Woolkalis MJ, Woulfe DS, Brass LF: Thrombin responses in human endothelial cells. Contributions from receptors other than PAR1 include the transactivation of PAR2 by thrombin-cleaved PAR1. J Biol Chem 2000;275:13502-13509.
    • (2000) J Biol Chem , vol.275 , pp. 13502-13509
    • O'Brien, P.J.1    Prevost, N.2    Molino, M.3    Hollinger, M.K.4    Woolkalis, M.J.5    Woulfe, D.S.6    Brass, L.F.7
  • 8
    • 0026515023 scopus 로고
    • Role of high-affinity thrombin receptors in post-clotting cellular effects of thrombin
    • Carney DH, Redin W, McCroskey L: Role of high-affinity thrombin receptors in post-clotting cellular effects of thrombin. Semin Thromb Hemost 1992;18: 91-103.
    • (1992) Semin Thromb Hemost , vol.18 , pp. 91-103
    • Carney, D.H.1    Redin, W.2    McCroskey, L.3
  • 9
    • 0024104359 scopus 로고
    • Synthetic peptides bind to high-affinity thrombin receptors and modulate thrombin mitogenesis
    • Glenn KC, Frost GH, Bergmann JS, Carney DH: Synthetic peptides bind to high-affinity thrombin receptors and modulate thrombin mitogenesis. Pept Res 1988;1:65-73.
    • (1988) Pept Res , vol.1 , pp. 65-73
    • Glenn, K.C.1    Frost, G.H.2    Bergmann, J.S.3    Carney, D.H.4
  • 10
    • 0033558796 scopus 로고    scopus 로고
    • Thrombin peptide, TP508, induces differential gene expression in fibroblasts through a nonproteolytic activation pathway
    • Sower LE, Payne DA, Meyers R, Carney DH: Thrombin peptide, TP508, induces differential gene expression in fibroblasts through a nonproteolytic activation pathway. Exp Cell Res 1999;247:422-431.
    • (1999) Exp Cell Res , vol.247 , pp. 422-431
    • Sower, L.E.1    Payne, D.A.2    Meyers, R.3    Carney, D.H.4
  • 14
    • 0034476941 scopus 로고    scopus 로고
    • Thrombin peptide TP508 accelerates closure of dermal excisions in animal tissue with surgically induced ischemia
    • Norfleet AM, Huang Y, Sower LE, Redin WR, Fritz RR, Carney DH: Thrombin peptide TP508 accelerates closure of dermal excisions in animal tissue with surgically induced ischemia. Wound Repair Regen 2000;8:517-529.
    • (2000) Wound Repair Regen , vol.8 , pp. 517-529
    • Norfleet, A.M.1    Huang, Y.2    Sower, L.E.3    Redin, W.R.4    Fritz, R.R.5    Carney, D.H.6
  • 15
    • 18244410123 scopus 로고    scopus 로고
    • Thrombin peptide (TP508) promotes fracture repair by upregulating inflammatory mediators, early growth factors, and increasing angiogenesis
    • Wang H, Li X, Tomin E, Doty SB, Lane JM, Carney DH, Ryaby JT: Thrombin peptide (TP508) promotes fracture repair by upregulating inflammatory mediators, early growth factors, and increasing angiogenesis. J Orthop Res 2005;23:671-679.
    • (2005) J Orthop Res , vol.23 , pp. 671-679
    • Wang, H.1    Li, X.2    Tomin, E.3    Doty, S.B.4    Lane, J.M.5    Carney, D.H.6    Ryaby, J.T.7
  • 17
    • 11044232864 scopus 로고    scopus 로고
    • Bone formation is enhanced by thrombin-related peptide TP508 during distraction osteogenesis
    • Li G, Ryaby JT, Carney DH, Wang H: Bone formation is enhanced by thrombin-related peptide TP508 during distraction osteogenesis. J Orthop Res 2005;23:196-202.
    • (2005) J Orthop Res , vol.23 , pp. 196-202
    • Li, G.1    Ryaby, J.T.2    Carney, D.H.3    Wang, H.4
  • 20
    • 0242552104 scopus 로고    scopus 로고
    • Adipose-derived adult stem cells: Isolation, characterization, and differentiation potential
    • Gimble J, Guilak F: Adipose-derived adult stem cells: isolation, characterization, and differentiation potential. Cytotherapy 2003;5:362-369.
    • (2003) Cytotherapy , vol.5 , pp. 362-369
    • Gimble, J.1    Guilak, F.2
  • 21
    • 34548791742 scopus 로고    scopus 로고
    • VEGF receptor Flk-1 plays an important role in c-kit expression in adipose tissue derived stem cells
    • Bai X, Sadat S, Gehmert S, Alt E, Song YH: VEGF receptor Flk-1 plays an important role in c-kit expression in adipose tissue derived stem cells. FEBS Lett 2007;581:4681-4684.
    • (2007) FEBS Lett , vol.581 , pp. 4681-4684
    • Bai, X.1    Sadat, S.2    Gehmert, S.3    Alt, E.4    Song, Y.H.5
  • 24
    • 33646003861 scopus 로고    scopus 로고
    • Thrombin and PAR-1 stimulate differentiation of bone marrow-derived endothelial progenitor cells
    • Tarzami ST, Wang G, Li W, Green L, Singh JP: Thrombin and PAR-1 stimulate differentiation of bone marrow-derived endothelial progenitor cells. J Thromb Haemost 2006;4:656-663.
    • (2006) J Thromb Haemost , vol.4 , pp. 656-663
    • Tarzami, S.T.1    Wang, G.2    Li, W.3    Green, L.4    Singh, J.P.5
  • 25
    • 0034763273 scopus 로고    scopus 로고
    • Thrombin induces increased expression and secretion of VEGF from human FS4 fibroblasts, DU145 prostate cells and CHRF megakaryocytes
    • Huang YQ, Li JJ, Hu L, Lee M, Karpatkin S: Thrombin induces increased expression and secretion of VEGF from human FS4 fibroblasts, DU145 prostate cells and CHRF megakaryocytes. Thromb Haemost 2001;86:1094-1098.
    • (2001) Thromb Haemost , vol.86 , pp. 1094-1098
    • Huang, Y.Q.1    Li, J.J.2    Hu, L.3    Lee, M.4    Karpatkin, S.5
  • 26
    • 0035853404 scopus 로고    scopus 로고
    • Thrombomodulin prolongs thrombin-induced extracellular signal-regulated kinase phosphorylation and nuclear retention in endothelial cells
    • Olivot JM, Estebanell E, Lafay M, Brohard B, Aiach M, Rendu F: Thrombomodulin prolongs thrombin-induced extracellular signal-regulated kinase phosphorylation and nuclear retention in endothelial cells. Circ Res 2001;88:681-687.
    • (2001) Circ Res , vol.88 , pp. 681-687
    • Olivot, J.M.1    Estebanell, E.2    Lafay, M.3    Brohard, B.4    Aiach, M.5    Rendu, F.6
  • 28
    • 33747185071 scopus 로고    scopus 로고
    • The angiopoietin pathway is modulated by PAR-1 activation on human endothelial progenitor cells
    • Smadja DM, Laurendeau I, Avignon C, Vidaud M, Aiach M, Gaussem P: The angiopoietin pathway is modulated by PAR-1 activation on human endothelial progenitor cells. J Thromb Haemost 2006;4:2051-2058.
    • (2006) J Thromb Haemost , vol.4 , pp. 2051-2058
    • Smadja, D.M.1    Laurendeau, I.2    Avignon, C.3    Vidaud, M.4    Aiach, M.5    Gaussem, P.6
  • 29
    • 4644286776 scopus 로고    scopus 로고
    • The role of angiopoietins in the development of endothelial cells from cord blood CD34+ progenitors
    • Hildbrand P, Cirulli V, Prinsen RC, Smith KA, Torbett BE, Salomon DR, Crisa L: The role of angiopoietins in the development of endothelial cells from cord blood CD34+ progenitors. Blood 2004;104:2010-2019.
    • (2004) Blood , vol.104 , pp. 2010-2019
    • Hildbrand, P.1    Cirulli, V.2    Prinsen, R.C.3    Smith, K.A.4    Torbett, B.E.5    Salomon, D.R.6    Crisa, L.7
  • 30
    • 6344257143 scopus 로고    scopus 로고
    • On the mode of action of thrombin-induced angiogenesis: Thrombin peptide, TP508, mediates effects in endothelial cells via alphavbeta3 integrin
    • Tsopanoglou NE, Papaconstantinou ME, Flordellis CS, Maragoudakis ME: On the mode of action of thrombin-induced angiogenesis: thrombin peptide, TP508, mediates effects in endothelial cells via alphavbeta3 integrin. Thromb Haemost 2004;92: 846-857.
    • (2004) Thromb Haemost , vol.92 , pp. 846-857
    • Tsopanoglou, N.E.1    Papaconstantinou, M.E.2    Flordellis, C.S.3    Maragoudakis, M.E.4
  • 33
    • 0034581330 scopus 로고    scopus 로고
    • Thrombin peptide, TP508, stimulates angiogenic responses in animal models of dermal wound healing, in chick chorioallantoic membranes, and in cultured human aortic and microvascular endothelial cells
    • Norfleet AM, Bergmann JS, Carney DH: Thrombin peptide, TP508, stimulates angiogenic responses in animal models of dermal wound healing, in chick chorioallantoic membranes, and in cultured human aortic and microvascular endothelial cells. Gen Pharmacol 2000;35:249-254.
    • (2000) Gen Pharmacol , vol.35 , pp. 249-254
    • Norfleet, A.M.1    Bergmann, J.S.2    Carney, D.H.3
  • 34
    • 35948999615 scopus 로고    scopus 로고
    • Intracoronary administration of autologous adipose tissue-derived stem cells improves left ventricular function, perfusion, and remodelling after acute myocardial infarction
    • Valina C, Pinkernell K, Song YH, Bai X, Sadat S, Campeau RJ, Le Jemtel TH, Alt E: Intracoronary administration of autologous adipose tissue-derived stem cells improves left ventricular function, perfusion, and remodelling after acute myocardial infarction. Eur Heart J 2007;28:2667-2677.
    • (2007) Eur Heart J , vol.28 , pp. 2667-2677
    • Valina, C.1    Pinkernell, K.2    Song, Y.H.3    Bai, X.4    Sadat, S.5    Campeau, R.J.6    Le Jemtel, T.H.7    Alt, E.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.