Inhibition of viral group-1 and group-2 neuraminidases by oseltamivir: A comparative structural analysis by the ScrewFit algorithm

Biophysical Chemistry

Volumn 141, Issue 1, 2009, Pages 117-123

  Calligari, Paolo A ^a,b,c   Kneller, Gerald R ^a,d,e   Giansanti, Andrea ^f   Ascenzi, Paolo ^g,h   Porrello, Alessandro ⁱ   Bocedi, Alessio ^h  

^a CENTRE DE BIOPHYSIQUE MOLÉCULAIRE   (France)

^b INSTITUT LAUE LANGEVIN   (France)

^c LABORATOIRE LÉON BRILLOUIN   (France)

^d UNIVERSITÉ D'ORLÉANS   (France)

^e SYNCHROTRON SOLEIL   (France)

^f SAPIENZA UNIVERSITY OF ROME   (Italy)

^g NATIONAL INSTITUTE FOR INFECTIOUS DISEASES L SPALLANZANI   (Italy)

^h ROMA TRE UNIVERSITY   (Italy)

ⁱ DUKE UNIVERSITY   (United States)

Author keywords

Comparative structural analysis; Enzyme structure; Neuraminidase; Oseltamivir binding; ScrewFit algorithm

Indexed keywords

ARGININE; ASPARTIC ACID; GLUTAMIC ACID; GLYCINE; OSELTAMIVIR; SERINE; SIALIDASE INHIBITOR; UNCLASSIFIED DRUG; VALINE; VIRUS NEURAMINIDASE 1; VIRUS NEURAMINIDASE 8; VIRUS NEURAMINIDASE 9; VIRUS SIALIDASE;

ALGORITHM; ARTICLE; DRUG DESIGN; DRUG PROTEIN BINDING; ENZYME CONFORMATION; ENZYME STRUCTURE; GEOMETRY; INFLUENZA VIRUS A H5N1; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STRUCTURE ANALYSIS;

ALGORITHMS; ENZYME INHIBITORS; INFLUENZA A VIRUS; MODELS, MOLECULAR; NEURAMINIDASE; OSELTAMIVIR; PEPTIDES; PROTEIN CONFORMATION;

AVIAN INFLUENZA VIRUS; ORTHOMYXOVIRIDAE;

EID: 60249087300     PISSN: 03014622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bpc.2009.01.004     Document Type: Article

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