Hepatoma-derived Growth Factor Represses SET and MYND Domain Containing 1 Gene Expression through Interaction with C-terminal Binding Protein

Journal of Molecular Biology

Volumn 386, Issue 4, 2009, Pages 938-950

  Yang, Jun ^a   Everett, Allen D ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

CtBP; HDGF; repressor; SMYD1; transcription

Indexed keywords

C TERMINAL BINDING PROTEIN; HEPATOMA DERIVED GROWTH FACTOR; REPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARDIOVASCULAR FUNCTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEVELOPMENTAL GENE; DNA BINDING; DOWN REGULATION; FLUORESCENCE MICROSCOPY; FUSION GENE; GENE ACTIVITY; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE FUSION; GENE INACTIVATION; GENE INTERACTION; GENE OVEREXPRESSION; GENE REPRESSION; GENE TARGETING; KNOCKOUT GENE; MICROARRAY ANALYSIS; MOUSE; MYOBLAST; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION; REPORTER GENE; TRANSCRIPTION REGULATION;

EID: 60149109389     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2008.12.080     Document Type: Article

References (48)

1. Everett A.D., Lobe D.R., Matsumura M.E., Nakamura H., and McNamara C.A. Hepatoma-derived growth factor stimulates smooth muscle cell growth and is expressed in vascular development. J. Clin. Invest. 105 (2000) 567-575
2. Nakamura H., Izumoto Y., Kambe H., Kuroda T., Mori T., Kawamura K., et al. Molecular cloning of complementary DNA for a novel human hepatoma-derived growth factor. Its homology with high mobility group-1 protein. J. Biol. Chem. 269 (1994) 25143-25149
3. Oliver J.A., and Al-Awqati Q. An endothelial growth factor involved in rat renal development. J. Clin. Invest. 102 (1998) 1208-1219
4. Everett A.D., Stoops T., and McNamara C.A. Nuclear targeting is required for hepatoma-derived growth factor-stimulated mitogenesis in vascular smooth muscle cells. J. Biol. Chem. 276 (2001) 37564-37568
5. Kishima Y., Yamamoto H., Izumoto Y., Yoshida K., Enomoto H., Yamamoto M., et al. Hepatoma-derived growth factor stimulates cell growth after translocation to the nucleus by nuclear localization signals. J. Biol. Chem. 277 (2002) 10315-10322
6. Stec I., Nagl S.B., van Ommen G.B., and den Dunnen J.T. The PWWP domain: a potential protein-protein interaction domain in nuclear proteins influencing differentiation?. FEBS Lett. 473 (2000) 1-5
7. Maurer-Stroh S., Dickens N.J., Hughes-Davies L., Kouzarides T., Eisenhaber F., and Ponting C.P. The Tudor domain 'Royal Family': Tudor, plant Agenet, Chromo, PWWP and MBT domains. Trends Biochem. Sci. 28 (2003) 69-74
8. Nameki N., Tochio N., Koshiba S., Inoue M., Yabuki T., Aoki M., et al. Solution structure of the PWWP domain of the hepatoma-derived growth factor family. Protein Sci. 14 (2005) 756-764
9. Lukasik S.M., Cierpicki T., Borloz M., Grembecka J., Everett A.D., and Bushweller J.H. High resolution structure of the HDGF PWWP domain: a potential DNA binding domain. Protein Sci. 15 (2006) 314-323
10. Qiu C., Sawada K., Zhang X., and Cheng X. The PWWP domain of mammalian DNA methyltransferase Dnmt3b defines a new family of DNA-binding folds. Nature Struct. Biol. 9 (2002) 217-224
11. Gottlieb P.D., Pierce S.A., Sims R.J., Yamagishi H., Weihe E.K., Harriss V J., et al. Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis. Nature Genet. 31 (2002) 25-32
12. Ge Y., Pu M., Gowher H., Wu H., Ding J., Jeltsch A., and Xu G. Chromatin targeting of de novo DNA methyltransferases by the PWWP domain. J. Biol. Chem. 279 (2004) 25447-25454
13. Yang J., and Everett A.D. Hepatoma-derived growth factor binds DNA through the N-terminal PWWP domain. BMC Mol. Biol. 31 (2007) 101
14. Chen T., Tsujimoto N., and Li E. The PWWP domain of Dnmt3a and Dnmt3b is required for directing DNA methylation to the major satellite repeats at pericentric heterochromatin. Mol. Cell. Biol. 24 (2004) 9048-9058
15. Everett A.D., Narron J.V., Stoops T., Nakamura H., and Tucker A. Hepatoma-derived growth factor is a pulmonary endothelial cell-expressed angiogenic factor. Am. J. Physiol. Lung Cell Mol. Physiol. 286 (2004) L1194-L1201
16. Okuda Y., Nakamura H., Yoshida K., Enomoto H., Uyama H., Hirotani T., et al. Hepatoma-derived growth factor induces tumorigenesis in vivo through both direct angiogenic activity and induction of vascular endothelial growth factor. Cancer Sci. 94 (2003) 1034-1041
17. Zhang J., Ren H., Yuan P., Lang W., Zhang L., and Mao L. Down-regulation of hepatoma-derived growth factor inhibits anchorage-independent growth and invasion of non-small cell lung cancer cells. Cancer Res. 66 (2006) 18-23
18. Hwang I., and Gottlieb D.P. The Bop gene adjacent to the mouse CD8b gene encodes distinct Zinc-finger proteins expressed in CTLs and in muscle. J. Immunol. 58 (1997) 1165-1174
19. Schaeper U., Boyd J.M., Verma S., Uhlmann E., Subramanian T., and Chinnadurai G. Molecular cloning and characterization of a cellular phosphoprotein that interacts with a conserved C-terminal domain of adenovirus E1A involved in negative modulation of oncogenic transformation. Proc. Natl Acad. Sci. USA 92 (1995) 10467-10471
20. Nibu Y., Zhang H., and Levine M. Interaction of short-range repressors with Drosophila CtBP in the embryo. Science, 280 (1998) 101-104
21. Chinnadurai G. CtBP, an unconventional transcriptional corepressor in development and oncogenesis. Mol. Cell 9 (2002) 213-224
22. Vo N., Fjeld C., and Goodman R.H. Acetylation of nuclear hormone receptor-interacting protein RIP140 regulates binding of the transcriptional corepressor CtBP. Mol. Cell. Biol. 21 (2001) 6181-6188
23. Boyd J.M., Subramanian T., Schaeper U., La Regina M., Bayley S., and Chinnadurai G. A region in the C-terminus of adenovirus 2/5 E1a protein is required for association with a cellular phosphoprotein and important for the negative modulation of T24-ras mediated transformation, tumorigenesis and metastasis. EMBO J. 12 (1993) 469-478
24. Criqui-Filipe P., Ducret C., Maira S.M., and Wasylyk B. Net, a negative Ras-switchable TCF, contains a second inhibition domain, the CID, that mediates repression through interactions with CtBP and de-acetylation. EMBO J. 18 (1999) 3392-3403
25. Weigert R., Silletta M.G., Spano S., Turacchio G., Cericola C., Colanzi A., et al. CtBP/BARS induces fission of Golgi membranes by acylating lysophosphatidic acid. Nature 402 (1999) 429-433
26. Turner J., and Crossley M. The CtBP family: enigmatic and enzymatic transcriptional co-repressors. BioEssays 23 (2001) 683-690
27. Verger A., Quinlan K.G., Crofts L.A., Spanò S., Corda D., Kable E.P., Braet F., and Crossley M. Mechanisms directing the nuclear localization of the CtBP family proteins. Mol. Cell. Biol. 26 (2006) 4882-4894
28. Kuroda T., Tanaka H., Nakamura H., Nishimune Y., and Kishimoto T. Hepatoma-derived growth factor-related protein (HRP)-1 gene in spermatogenesis in mice. Biochem. Biophys. Res. Commun. 262 (1999) 433-437
29. Izumoto Y., Kuroda T., Harada H., Kishimoto T., and Nakamura H. Hepatoma-derived growth factor belongs to a gene family in mice showing significant homology in the amino terminus. Biochem. Biophys. Res. Commun. 238 (1997) 26-32
30. Ikegame K., Yamamoto M., Kishima Y., Enomoto H., Yoshida K., Suemura M., et al. A new member of a hepatoma-derived growth factor gene family can translocate to the nucleus. Biochem. Biophys. Res. Commun. 266 (1999) 81-87
31. Singh D.P., Kimura A., Chylack Jr. L.T., and Shinohara T. Lens epithelium-derived growth factor (LEDGF/p75) and p52 are derived from a single gene by alternative splicing. Gene 242 (2000) 265-273
32. Dietz F., Franken S., Yoshida K., Nakamura H., Kappler J., and Gieselmann V. The family of hepatoma-derived growth factor proteins: characterization of a new member HRP-4 and classification of its subfamilies. Biochem. J. 366 (2002) 491-500
33. Shinohara T., Singh D.P., and Fatma N. LEDGF, a survival factor, activates stress-related genes. Prog. Retin. Eye Res. 21 (2002) 341-358
34. Everett A.D. Identification, cloning, and developmental expression of hepatoma-derived growth factor in the developing rat heart. Dev. Dynam. 222 (2001) 450-458
35. Uyama H., Tomita Y., Nakamura H., Nakamori S., Zhang B., Hoshida Y., et al. Hepatoma-derived growth factor is a novel prognostic factor for patients with pancreatic cancer. Clin. Cancer Res. 12 (2006) 6043-6048
36. Yamamoto S., Tomita Y., Hoshida Y., Takiguchi S., Fujiwara Y., Yasuda T., et al. Expression of hepatoma-derived growth factor is correlated with lymph node metastasis and prognosis of gastric carcinoma. Clin. Cancer Res. 12 (2006) 117-122
37. Ren H., Tang X., Lee J.J., Feng L., Everett A.D., Hong W.K., et al. Expression of hepatoma-derived growth factor is a strong prognostic predictor for patients with early-stage non-small-cell lung cancer. J. Clin. Oncol. 22 (2004) 3230-3237
38. Stec I., Nagl S.B., van Ommen G.J.B., and den Dunnen J.T. The PWWP domain: a potential protein-protein interaction domain in nuclear proteins influencing differentiation?. FEBS Lett. 473 (2000) 1-5
39. Maurer-Stroh S., Dickens N.J., Hughes-Davies L., Kouzarides T., Eisenhaber F., and Ponting C.P. The Tudor domain 'Royal Family': Tudor, plant Agenet, Chromo, PWWP and MBT domains. Trends Biochem. Sci. 28 (2003) 69-74
40. Slater L.M., and Allen M.D. Bycroft M. Structural variation in PWWP domains. J. Mol. Biol. 330 (2003) 571-576
41. Masselink H., and Bernards R. The adenovirus E1A binding protein BS69 is a corepressors of transcription through recruitment of N-CoR. Oncogene 19 (2000) 1538-1546
42. Vary J.C., Gangaraju V.K., Qin J., Landel C.C., Kooperberg C., Bartholomew B., and Tsukiyama T. Yeast Isw1p forms two separable complexes in vivo. Mol. Cell. Biol. 23 (2003) 80-91
43. Bachman K.E., Rountree M.R., and Baylin S.B. Dnmt3a and Dnmt3b are transcriptional repressors that exhibit unique localization properties to heterochromatin. J. Biol. Chem. 276 (2001) 32282-32287
44. Poortinga G., Watanabe M., and Parkhurst S.M. Drosophila CtBP: a Hairy-interacting protein required for embryonic segmentation and hairy-mediated transcriptional repression. EMBO J. 17 (1998) 2067-2078
45. Lepourcelet M., Tou L., Cai L., Sawada J., Lazar A.J., Glickman J.N., et al. Insights into developmental mechanisms and cancers in the mammalian intestine derived from serial analysis of gene expression and study of the hepatoma-derived growth factor (HDGF). Development 132 (2005) 415-427
46. Radonic A., Thulke S., Mackay I.M., Landt O., Siegert W., and Nitschea A. Guideline to reference gene selection for quantitative real-time PCR. Biochem. Biophys. Res. Commun. 313 (2004) 856-862
47. - ΔΔCt method. Methods 25 (2001) 402-408
48. Deltour S., Pinte S., Guerardel C., Wasylyk B., and Leprince D. The human candidate tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif. Mol. Cell. Biol. 22 (2002) 4890-4901