Hepatoma-derived growth factor is a pulmonary endothelial cell-expressed angiogenic factor

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 286, Issue 6 30-6, 2004, Pages

  Everett, Allen D ^a,c   Narron, Jill V ^a   Stoops, Tamara ^a   Nakamura, Hideji ^b   Tucker, Amy ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b HYOGO COLLEGE OF MEDICINE   (Japan)

^c JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

Angiogenesis; Cell migration; Growth factors; Lung

Indexed keywords

ANGIOGENIC FACTOR; BIOCHEMICAL MARKER; BROXURIDINE; CELL PROTEIN; GROWTH FACTOR; HEPATOMA DERIVED GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA ANTIBODY; TRANSFORMING GROWTH FACTOR BETA2; UNCLASSIFIED DRUG; VASCULOTROPIN;

ADENOVIRUS; ANGIOGENESIS; ANIMAL TISSUE; ARTICLE; CELL INTERACTION; CELL MIGRATION; CELL PROLIFERATION; CHICKEN; CHORIOALLANTOIS; CONTROLLED STUDY; CULTURE MEDIUM; ENDOTHELIUM CELL; ENZYME ACTIVATION; FETUS LUNG; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LUNG ENDOTHELIUM; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

ANIMALS; CELL MOVEMENT; CELLS, CULTURED; CHICK EMBRYO; ENDOTHELIUM, VASCULAR; HUMANS; IMMUNOHISTOCHEMISTRY; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LUNG; MAP KINASE SIGNALING SYSTEM; MICROCIRCULATION; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MITOGENS; NEOVASCULARIZATION, PHYSIOLOGIC;

EID: 2442715235     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00427.2003     Document Type: Article

References (18)

1. Brown CB, Drake CJ, and Barnett JV. Antibodies directed against the chicken type II TGFbeta receptor identify endothelial cells in the developing chicken and quail. Dev Dyn 215: 79-85, 1999.
2. Burri P. Development and growth of the lung. In: Lung Growth and Development, edited by McDonald J. New York: Dekker, 1997, p. 1-35.
3. Carmeliet P, Ferreira V, Breier G, Pollefeyt S, Kieckens L, Gertsenstein M, Fahrig M, Vandenhoeck A, Harpal K, Eberhardt C, Declercq C, Pawling J, Moons L, Collen D, Risau W, Nagy A. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380: 435-439, 1996.
4. Conway EM, Collen D, and Carmeliet P. Molecular mechanisms of blood vessel growth. Cardiovasc Res 49: 507-521, 2001.
5. DeMello DE, Sawyer D, Galvin N, and Reid LM. Early fetal development of lung vasculature, Am J Respir Cell Mol Biol 16: 568-581, 1997.
6. Everett AD. Identification, cloning, and developmental expression of hepatoma-derived growth factor in the developing rat heart. Dev Dyn 222: 450-458, 2001.
7. Everett AD, Lobe DR, Matsumura ME, Nakamura H, and McNamara CA. Hepatoma-derived growth factor stimulates smooth muscle cell growth and is expressed in vascular development. J Clin Invest 105: 567-575, 2000.
8. Everett AD, Stoops T, and McNamara CA. Nuclear targeting is required for hepatoma-derived growth factor-stimulated mitogenesis in vascular smooth muscle cells. J Biol Chem 276: 37564-37568, 2001.
9. Ge H, Si Y, and Wolffe AP. A novel transcriptional coactivator, p52, functionally interacts with the essential splicing factor ASF/SF2. Mol Cell 2: 751-759, 1998.
10. Gerber HP, McMurtrey A, Kowalski J, Keyt BA, Dixit V, and Ferrara N. Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinases/Akt signal transduction pathway. Requirement of Flk-1/KDR activation. J Biol Chem 273: 30336-30434, 1998.
11. Hardy S, Kitamura M, Harris-Stansil T, Dai Y, and Phipps ML. Construction of adenovirus vectors through Cre-lox recombination. J Virol 71: 1842-1849, 1997.
12. Kishima Y, Yamamoto H, Izumoto Y, Yoshida K, Enomoto H, Yamamoto M, Kuroda T, Ito H, Yoshizaki K, and Nakamura H. Hepatoma-derived growth factor stimulates cell growth after translocation to the nucleus by nuclear localization signals. J Biol Chem 277: 10315-103122, 2002.
13. Maniscalco WM, Watkins RH, Pryhuber GS, Bhatt A, Shea C, and Huyck H. Angiogenic factors and alveolar vasculature: development and alterations by injury in very premature baboons. Am J Physiol Lung Cell Mol Physiol 282: L811-L823, 2002.
14. Nakamura H, Izumoto Y, Kambe H, Kuroda T, Mori T, Kawamura K, Yamamoto H, and Kishimoto T. Molecular cloning of complementary DNA for a novel human hepatoma-derived growth factor. Its homology with high mobility group-1 protein. J Biol Chem 269: 25143-25149, 1994.
15. Oliver JA and Al-Awqati Q. An endothelial growth factor involved in rat renal development. J Clin Invest 102: 1208-1219, 1998.
16. Pedram A, Razandi M, and Levin E. ERK/JUN kinase cross-talk underlies vascular endothelial cell growth factor-induced endothelial cell proliferation. J Biol Chem 273: 26722-26728, 1998.
17. Schwarz MA, Zhang F, Lane JE, Schachtner S, Jin Y, Deutsch G, Starnes V, and Pitt BR. Angiogenesis and morphogenesis of murine fetal distal lung in an allograft model. Am J Physiol Lung Cell Mol Physiol 278: L1000-L1007, 2000.
18. Singh S, Zheng JJ, Peiper SC, and Mclaughlin BJ. Gene expression profile of ARPE-19 during repair of the monolayer. Graefes Arch Clin Exp Ophthalmol 239: 946-951, 2001.