메뉴 건너뛰기




Volumn 81, Issue 4, 2009, Pages 797-804

A pyrrole-imidazole polyamide targeting transforming growth factor-β1 inhibits restenosis and preserves endothelialization in the injured artery

Author keywords

Pyrrole imidazole polyamide; Rat; Restenosis; Transforming growth factor 1

Indexed keywords

COLLAGEN TYPE 1; CONNECTIVE TISSUE GROWTH FACTOR; FIBRONECTIN; IMIDAZOLE; LECTIN; LOW DENSITY LIPOPROTEIN RECEPTOR; POLYAMIDE; PYRROLE DERIVATIVE; TRANSFORMING GROWTH FACTOR BETA1;

EID: 60149106394     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvn355     Document Type: Article
Times cited : (47)

References (39)
  • 1
    • 0033393520 scopus 로고    scopus 로고
    • Pathology of in-stent restenosis
    • Virmani R, Farb A. Pathology of in-stent restenosis. Curr Opin Lipidol 1999;10:499-506.
    • (1999) Curr Opin Lipidol , vol.10 , pp. 499-506
    • Virmani, R.1    Farb, A.2
  • 2
    • 3543064732 scopus 로고    scopus 로고
    • Cost-effectiveness of sirolimus-eluting stents for treatment of complex coronary stenoses: Results from the Sirolimus-Eluting Balloon Expandable Stent in the Treatment of Patients With De Novo Native Coronary Artery Lesions (SIRIUS) trial
    • Cohen DJ, Bakhai A, Shi C, Githiora L, Lavelle T, Berezin RH et al. Cost-effectiveness of sirolimus-eluting stents for treatment of complex coronary stenoses: results from the Sirolimus-Eluting Balloon Expandable Stent in the Treatment of Patients With De Novo Native Coronary Artery Lesions (SIRIUS) trial. Circulation 2004;110:508-514.
    • (2004) Circulation , vol.110 , pp. 508-514
    • Cohen, D.J.1    Bakhai, A.2    Shi, C.3    Githiora, L.4    Lavelle, T.5    Berezin, R.H.6
  • 3
    • 0037044449 scopus 로고    scopus 로고
    • Angiographic findings of the multicenter Randomized Study With the Sirolimus-Eluting Bx Velocity Balloon-Expandable Stent (RAVEL): Sirolimus-eluting stents inhibit restenosis irrespective of the vessel size
    • Regar E, Serruys PW, Bode C, Holubarsch C, Guermonprez JL, Wijns W et al. Angiographic findings of the multicenter Randomized Study With the Sirolimus-Eluting Bx Velocity Balloon-Expandable Stent (RAVEL): sirolimus-eluting stents inhibit restenosis irrespective of the vessel size. Circulation 2002;106:1949-1956.
    • (2002) Circulation , vol.106 , pp. 1949-1956
    • Regar, E.1    Serruys, P.W.2    Bode, C.3    Holubarsch, C.4    Guermonprez, J.L.5    Wijns, W.6
  • 4
    • 0042388295 scopus 로고    scopus 로고
    • Randomized study to assess the effectiveness of slow- and moderate-release polymer-based paclitaxel-eluting stents for coronary artery lesions
    • Colombo A, Drzewiecki J, Banning A, Grube E, Hauptmann K, Silber S et al. Randomized study to assess the effectiveness of slow- and moderate-release polymer-based paclitaxel-eluting stents for coronary artery lesions. Circulation 2003;108:788-794.
    • (2003) Circulation , vol.108 , pp. 788-794
    • Colombo, A.1    Drzewiecki, J.2    Banning, A.3    Grube, E.4    Hauptmann, K.5    Silber, S.6
  • 6
    • 3242741265 scopus 로고    scopus 로고
    • Effectiveness of sirolimus-eluting stent implantation for treatment of in-stent restenosis after brachytherapy failure
    • Iakovou I, Sangiorgi GM, Stankovic G, Corvaja N, Michev I, Chieffo A et al. Effectiveness of sirolimus-eluting stent implantation for treatment of in-stent restenosis after brachytherapy failure. Am J Cardiol 2004;94:351-354.
    • (2004) Am J Cardiol , vol.94 , pp. 351-354
    • Iakovou, I.1    Sangiorgi, G.M.2    Stankovic, G.3    Corvaja, N.4    Michev, I.5    Chieffo, A.6
  • 7
    • 8544222631 scopus 로고    scopus 로고
    • Sirolimus-eluting stents for the prevention of restenosis in a worst-case scenario of diffuse and recurrent in-stent restenosis
    • Werner GS, Emig U, Krack A, Schwarz G, Figulla HR. Sirolimus-eluting stents for the prevention of restenosis in a worst-case scenario of diffuse and recurrent in-stent restenosis. Catheter Cardiovasc Interv 2004;63:259-264.
    • (2004) Catheter Cardiovasc Interv , vol.63 , pp. 259-264
    • Werner, G.S.1    Emig, U.2    Krack, A.3    Schwarz, G.4    Figulla, H.R.5
  • 8
    • 0020502095 scopus 로고
    • Mechanisms of stenosis after arterial injury
    • Clowes AW, Reidy MA, Clowes MM. Mechanisms of stenosis after arterial injury. Lab Invest 1983;49:208-215.
    • (1983) Lab Invest , vol.49 , pp. 208-215
    • Clowes, A.W.1    Reidy, M.A.2    Clowes, M.M.3
  • 10
    • 0026450848 scopus 로고
    • Expression of transforming growth factor-/31 is increased in human vascular restenosis lesions
    • Nikol S, Isner JM, Pickering JG, Kearney M, Leclerc G, Weir L. Expression of transforming growth factor-/31 is increased in human vascular restenosis lesions. J Clin Invest 1992;90:1582-1592.
    • (1992) J Clin Invest , vol.90 , pp. 1582-1592
    • Nikol, S.1    Isner, J.M.2    Pickering, J.G.3    Kearney, M.4    Leclerc, G.5    Weir, L.6
  • 11
    • 0025800329 scopus 로고
    • Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression in human vascular smooth muscle cells
    • Amento EP, Ehsani N, Palmer H, Libby P. Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression in human vascular smooth muscle cells. Arterioscler Thromb 1991;11:1223-1230.
    • (1991) Arterioscler Thromb , vol.11 , pp. 1223-1230
    • Amento, E.P.1    Ehsani, N.2    Palmer, H.3    Libby, P.4
  • 12
    • 0033602671 scopus 로고    scopus 로고
    • Transforming growth factor-beta (TGF-beta) type I and type II receptors are both required for TGF-beta-mediated extracellular matrix production in lung fibroblasts
    • Zhao Y. Transforming growth factor-beta (TGF-beta) type I and type II receptors are both required for TGF-beta-mediated extracellular matrix production in lung fibroblasts. Mol Cell Endocrinol 1999;150:91- 97.
    • (1999) Mol Cell Endocrinol , vol.150 , pp. 91-97
    • Zhao, Y.1
  • 13
    • 0034641666 scopus 로고    scopus 로고
    • Ribozyme oligonucleotides against transforming growth factor-β inhibited neointimal formation after vascular injury in rat model: Potential application of ribozyme strategy to treat cardiovascular disease
    • Yamamoto K, Morishita R, Tomita N, Shimozato T, Nakagami H, Kikuchi A et al. Ribozyme oligonucleotides against transforming growth factor-β inhibited neointimal formation after vascular injury in rat model: potential application of ribozyme strategy to treat cardiovascular disease. Circulation 2000;102:1308-1314.
    • (2000) Circulation , vol.102 , pp. 1308-1314
    • Yamamoto, K.1    Morishita, R.2    Tomita, N.3    Shimozato, T.4    Nakagami, H.5    Kikuchi, A.6
  • 14
    • 0347318097 scopus 로고    scopus 로고
    • Chimeric DNA-RNA hammerhead ribozyme targeting transforming growth factor-h1 mRNA inhibits neointima formation in rat carotid artery after balloon injury
    • Ando H, Fukuda N, Kotani M, Yokoyama S, Kunimoto S, Matsumoto K et al. Chimeric DNA-RNA hammerhead ribozyme targeting transforming growth factor-h1 mRNA inhibits neointima formation in rat carotid artery after balloon injury. Eur J Pharmacol 2004;483:207-214.
    • (2004) Eur J Pharmacol , vol.483 , pp. 207-214
    • Ando, H.1    Fukuda, N.2    Kotani, M.3    Yokoyama, S.4    Kunimoto, S.5    Matsumoto, K.6
  • 15
    • 0029786013 scopus 로고    scopus 로고
    • Recognition of DNA by designed ligands at subnanomolar concentrations
    • Trauger JW, Baird EE, Dervan PB. Recognition of DNA by designed ligands at subnanomolar concentrations. Nature 1996;382:559-561.
    • (1996) Nature , vol.382 , pp. 559-561
    • Trauger, J.W.1    Baird, E.E.2    Dervan, P.B.3
  • 16
    • 0031215078 scopus 로고    scopus 로고
    • On the pairing rules for recognition in the minor groove of DNA by pyrrole-imidazole polyamides
    • White S, Baird EE, Dervan PB. On the pairing rules for recognition in the minor groove of DNA by pyrrole-imidazole polyamides. Chem Biol 1997;4:569-578.
    • (1997) Chem Biol , vol.4 , pp. 569-578
    • White, S.1    Baird, E.E.2    Dervan, P.B.3
  • 17
    • 16544383435 scopus 로고    scopus 로고
    • Biology of N-methylpyrrole-N-methylimidazole hairpin polyamide
    • Murty MS, Sugiyama H. Biology of N-methylpyrrole-N-methylimidazole hairpin polyamide. Biol Pharm Bull 2004;27:468-474.
    • (2004) Biol Pharm Bull , vol.27 , pp. 468-474
    • Murty, M.S.1    Sugiyama, H.2
  • 19
    • 0036712067 scopus 로고    scopus 로고
    • Sequence-specific protection of plasmid DNA from restriction endonuclease hydrolysis by pyrrole-imidazole-cyclopropapyrroloindole conjugates
    • Fujimoto K, Iida H, Kawakami M, Bando T, Tao ZF, Sugiyama H. Sequence-specific protection of plasmid DNA from restriction endonuclease hydrolysis by pyrrole-imidazole-cyclopropapyrroloindole conjugates. Nucleic Acids Res 2002;30:3748-3753.
    • (2002) Nucleic Acids Res , vol.30 , pp. 3748-3753
    • Fujimoto, K.1    Iida, H.2    Kawakami, M.3    Bando, T.4    Tao, Z.F.5    Sugiyama, H.6
  • 20
    • 16544383435 scopus 로고    scopus 로고
    • Biology of N-methylpyrrole-N-methylimidazole hairpin polyamide
    • Murty MS, Sugiyama H. Biology of N-methylpyrrole-N-methylimidazole hairpin polyamide. Biol Pharm Bull 2004;27:468-474.
    • (2004) Biol Pharm Bull , vol.27 , pp. 468-474
    • Murty, M.S.1    Sugiyama, H.2
  • 21
    • 27144555400 scopus 로고    scopus 로고
    • Synthetic pyrrole-imidazole polyamide inhibits expression of the human transforming growth factor-b1 gene
    • Lai YM, Fukuda N, Ueno T, Matsuda H, Saito S, Matsumoto K et al. Synthetic pyrrole-imidazole polyamide inhibits expression of the human transforming growth factor-b1 gene. J Pharmacol Exp Therap 2005;315:571-575.
    • (2005) J Pharmacol Exp Therap , vol.315 , pp. 571-575
    • Lai, Y.M.1    Fukuda, N.2    Ueno, T.3    Matsuda, H.4    Saito, S.5    Matsumoto, K.6
  • 22
    • 33645457692 scopus 로고    scopus 로고
    • Development of gene silencing pyrrole-imidazole polyamide targeting the TGF-b1 promoter for treatment of progressive renal diseases
    • Matsuda H, Fukuda N, Ueno T, Tahira Y, Ayame H, Zhang W et al. Development of gene silencing pyrrole-imidazole polyamide targeting the TGF-b1 promoter for treatment of progressive renal diseases. J Am Soc Nephrol 2006;17:422-432.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 422-432
    • Matsuda, H.1    Fukuda, N.2    Ueno, T.3    Tahira, Y.4    Ayame, H.5    Zhang, W.6
  • 23
    • 0037131501 scopus 로고    scopus 로고
    • Molecular design of a pyrrole-imidazole hairpin polyamide for effective DNA alkylation
    • Bando T, Narita A, Saito I, Sugiyama H. Molecular design of a pyrrole-imidazole hairpin polyamide for effective DNA alkylation. Chemistry 2002;8:4781-4790.
    • (2002) Chemistry , vol.8 , pp. 4781-4790
    • Bando, T.1    Narita, A.2    Saito, I.3    Sugiyama, H.4
  • 24
    • 0025771126 scopus 로고
    • Quantitation of mRNA by the kinetic polymerase chain reaction assay: A tool for monitoring P-glycoprotein expression
    • Hoof T, Riordan JR, Tummler B. Quantitation of mRNA by the kinetic polymerase chain reaction assay: a tool for monitoring P-glycoprotein expression. Anal Biochem 1991;196:161-169.
    • (1991) Anal Biochem , vol.196 , pp. 161-169
    • Hoof, T.1    Riordan, J.R.2    Tummler, B.3
  • 25
    • 0029127782 scopus 로고
    • Characteristics and expression of transforming growth factor-β receptor subtypes on vascular smooth muscle cells from spontaneously hypertensive rats
    • Fukuda N, Kubo A, Izumi Y, Soma M, Kanmatsuse K. Characteristics and expression of transforming growth factor-β receptor subtypes on vascular smooth muscle cells from spontaneously hypertensive rats. J Hypertens 1995;13:831-837.
    • (1995) J Hypertens , vol.13 , pp. 831-837
    • Fukuda, N.1    Kubo, A.2    Izumi, Y.3    Soma, M.4    Kanmatsuse, K.5
  • 26
    • 0030750143 scopus 로고    scopus 로고
    • Insights in vessel development and vascular disorders using targeted inactivation and transfer of vascular endothelial growth factor, the tissue factor receptor, and the plasminogen system
    • Carmeliet P, Moons L, Dewerchin M, Mackman N, Luther T, Breier G et al. Insights in vessel development and vascular disorders using targeted inactivation and transfer of vascular endothelial growth factor, the tissue factor receptor, and the plasminogen system. Ann N Y Acad Sci 1997;811:191-206.
    • (1997) Ann N Y Acad Sci , vol.811 , pp. 191-206
    • Carmeliet, P.1    Moons, L.2    Dewerchin, M.3    Mackman, N.4    Luther, T.5    Breier, G.6
  • 27
    • 0036072237 scopus 로고    scopus 로고
    • Tranilast prevents activation of transforming growth factor-beta system, leukocyte accumulation, and neointimal growth in porcine coronary arteries after stenting
    • Ward MR, Agrotis A, Kanellakis P, Hall J, Jennings G, Bobik A. Tranilast prevents activation of transforming growth factor-beta system, leukocyte accumulation, and neointimal growth in porcine coronary arteries after stenting. Arterioscler Thromb Vasc Biol 2002;22:940-948.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 940-948
    • Ward, M.R.1    Agrotis, A.2    Kanellakis, P.3    Hall, J.4    Jennings, G.5    Bobik, A.6
  • 29
    • 0033802165 scopus 로고    scopus 로고
    • Connective tissue growth factor: Potential role in glomerulosclerosis and tubulointerstitial fibrosis
    • Gupta S, Clarkson MR, Duggan J. Connective tissue growth factor: potential role in glomerulosclerosis and tubulointerstitial fibrosis. Kidney Int 2000;58:1389-1399.
    • (2000) Kidney Int , vol.58 , pp. 1389-1399
    • Gupta, S.1    Clarkson, M.R.2    Duggan, J.3
  • 30
    • 16944364613 scopus 로고    scopus 로고
    • Human connective tissue growth factor is expressed in advanced atherosclerotic lesions
    • Oemar BS, Werner A, Garnier JM. Human connective tissue growth factor is expressed in advanced atherosclerotic lesions. Circulation 1997;95:831-839.
    • (1997) Circulation , vol.95 , pp. 831-839
    • Oemar, B.S.1    Werner, A.2    Garnier, J.M.3
  • 32
    • 29144514436 scopus 로고    scopus 로고
    • Oxidized LDL receptor LOX-1 is involved in neointimal hyperplasia after balloon arterial injury in a rat model
    • Hinagata J, Kakutani M, Fujii T, Naruko T, Inoue N, Fujita Y et al. Oxidized LDL receptor LOX-1 is involved in neointimal hyperplasia after balloon arterial injury in a rat model. Cardiovasc Res 2006;69:263-271.
    • (2006) Cardiovasc Res , vol.69 , pp. 263-271
    • Hinagata, J.1    Kakutani, M.2    Fujii, T.3    Naruko, T.4    Inoue, N.5    Fujita, Y.6
  • 33
    • 31444445203 scopus 로고    scopus 로고
    • Expression of lectin-like oxidized LDL receptor-1 in smooth muscle cells after vascular injury
    • Eto H, Miyata M, Kume N, Minami M, Itabe H, Orihara K et al. Expression of lectin-like oxidized LDL receptor-1 in smooth muscle cells after vascular injury. Biochem Biophys Res Commun 2006;341:591-598.
    • (2006) Biochem Biophys Res Commun , vol.341 , pp. 591-598
    • Eto, H.1    Miyata, M.2    Kume, N.3    Minami, M.4    Itabe, H.5    Orihara, K.6
  • 34
    • 0034616679 scopus 로고    scopus 로고
    • Transforming growth factor-b1 increases the expression of lectin-like oxidized low-density lipoprotein receptor-1
    • Minami M, Kume N, Kataoka H, Morimoto M, Hayashida K, Sawamura T et al. Transforming growth factor-b1 increases the expression of lectin-like oxidized low-density lipoprotein receptor-1. Biochem Biophys Res Commun 2000;272:357-361.
    • (2000) Biochem Biophys Res Commun , vol.272 , pp. 357-361
    • Minami, M.1    Kume, N.2    Kataoka, H.3    Morimoto, M.4    Hayashida, K.5    Sawamura, T.6
  • 35
    • 0023623241 scopus 로고
    • TGF-beta inhibition of endothelial cell proliferation: Alteration of EGF binding and EGF induced growth-regulatory (competence) gene expression
    • Takehara K, LeRoy EC, Grotendorst GR. TGF-beta inhibition of endothelial cell proliferation: alteration of EGF binding and EGF induced growth-regulatory (competence) gene expression. Cell 1987;49:415-422.
    • (1987) Cell , vol.49 , pp. 415-422
    • Takehara, K.1    LeRoy, E.C.2    Grotendorst, G.R.3
  • 36
    • 0022538577 scopus 로고
    • Inhibition of endothelial cell proliferation by type b -transforming growth factors: Interactions with acidic and basic fibroblast growth factors
    • Baird A, Durkin T. Inhibition of endothelial cell proliferation by type b -transforming growth factors: interactions with acidic and basic fibroblast growth factors. Biochem Biophys Res Commun 1986;138:476-482.
    • (1986) Biochem Biophys Res Commun , vol.138 , pp. 476-482
    • Baird, A.1    Durkin, T.2
  • 37
    • 0027298232 scopus 로고
    • The endothelium as a regulator of vascular smooth muscle proliferation
    • Scott-Burden T, Vanhoutte PM. The endothelium as a regulator of vascular smooth muscle proliferation. Circulation 1993;87(Suppl. V):V-51-V-55.
    • (1993) Circulation , vol.87 , Issue.SUPPL. V
    • Scott-Burden, T.1    Vanhoutte, P.M.2
  • 38
    • 0016693056 scopus 로고
    • Endothelial regeneration in the rat carotid artery and the significance of endothelial denudation in the pathogenesis of myointimal thickening
    • Fishman JA, Ryan GB, Karnovsky MJ. Endothelial regeneration in the rat carotid artery and the significance of endothelial denudation in the pathogenesis of myointimal thickening. Lab Invest 1975;32:339-351.
    • (1975) Lab Invest , vol.32 , pp. 339-351
    • Fishman, J.A.1    Ryan, G.B.2    Karnovsky, M.J.3
  • 39
    • 0018622880 scopus 로고    scopus 로고
    • Haudenschild CC, Schwartz SM. Endothelial regeneration, II: restitution of endothelial continuity. Lab Invest 1979;41:407-418.
    • Haudenschild CC, Schwartz SM. Endothelial regeneration, II: restitution of endothelial continuity. Lab Invest 1979;41:407-418.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.