Chronic granulomatous disease

Cellular and Molecular Life Sciences

Volumn 66, Issue 4, 2009, Pages 553-558

  Segal, B H ^a   Romani, L ^b   Puccetti, P ^b  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

^b UNIVERSITY OF PERUGIA   (Italy)

Author keywords

Chronic granulomatous disease; Indoleamine 2,3 dioxygenase; Inflammation; Interleukin 17; NADPH oxidase

Indexed keywords

INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 17; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE; TRYPTOPHAN;

ALLERGY; ASPERGILLOSIS; CHRONIC GRANULOMATOUS DISEASE; CLINICAL FEATURE; ENZYME ACTIVATION; FUNGUS GROWTH; GENE THERAPY; HOST RESISTANCE; HUMAN; IMMUNOLOGICAL TOLERANCE; INFLAMMATION; NEUTROPHIL COUNT; NONHUMAN; PROTEIN DEGRADATION; SHORT SURVEY; STEM CELL TRANSPLANTATION; T LYMPHOCYTE; TREATMENT RESPONSE;

ANIMALS; BACTERIAL INFECTIONS; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; GRANULOMATOUS DISEASE, CHRONIC; HUMANS; IMMUNE SYSTEM; IMMUNE TOLERANCE; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; INFLAMMATION; MYCOSES; NADPH OXIDASE; REACTIVE OXYGEN SPECIES; TRYPTOPHAN;

BACTERIA (MICROORGANISMS); MUS;

EID: 60149090343     PISSN: 1420682X     EISSN: 15691632     Source Type: Journal    
DOI: 10.1007/s00018-009-8506-y     Document Type: Short Survey

References (40)

1. Segal, B. H., Leto, T. L., Gallin, J. I., Malech, H. L. and Holland, S. M. (2000) Genetic, biochemical, and clinical features of chronic granulomatous disease. Medicine (Baltimore) 79, 170-200
2. Rosenzweig, S. D. (2008) Inflammatory manifestations in chronic granulomatous disease (CGD). J. Clin. Immunol. 28 Suppl 1, S67-72
3. Marciano, B. E., Rosenzweig, S. D., Kleiner, D. E., Anderson, V. L., Darnell, D. N., Anaya-O'Brien, S., Hilligoss, D. M., Malech, H. L., Gallin, J. I. and Holland, S. M. (2004) Gastrointestinal involvement in chronic granulomatous disease. Pediatrics 114, 462-468
4. Siddiqui, S., Anderson, V. L., Hilligoss, D. M., Abinun, M., Kuijpers, T. W., Masur, H., Witebsky, F. G., Shea, Y. R., Gallin, J. I., Malech, H. L. and Holland, S. M. (2007) Fulminant mulch pneumonitis: An emergency presentation of chronic granulomatous disease. Clin. Infect. Dis. 45, 673-681
5. Babior, B. M. (1999) NADPH oxidase: An update. Blood 93, 1464-1476
6. Thrasher, A. J., Keep, N. H., Wientjes, F. and Segal, A. W. (1994) Chronic granulomatous disease. Biochim. Biophys. Acta 1227, 1-24
7. Abo, A., Pick, E., Hall, A., Totty, N., Teahan, C. G. and Segal, A. W. (1991) Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1. Nature 353, 668-670
8. Knaus, U. G., Heyworth, P. G., Evans, T., Curnutte, J. T. and Bokoch, G. M. (1991) Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac 2. Science 254, 1512-1515
9. + flux. Nature 416, 291-297
10. Tkalcevic, J., Novelli, M., Phylactides, M., Iredale, J. P., Segal, A. W. and Roes, J. (2000) Impaired immunity and enhanced resistance to endotoxin in the absence of neutrophil elastase and cathepsin G. Immunity 12, 201-210
11. Segal, B. H., DeCarlo, E. S., Kwon-Chung, K. J., Malech, H. L., Gallin, J. I. and Holland, S. M. (1998) Aspergillus nidulans infection in chronic granulomatous disease. Medicine (Baltimore) 77, 345-354
12. Winkelstein, J. A., Marino, M. C., Johnston, R. B. Jr, Boyle, J., Curnutte, J., Gallin, J. I., Malech, H. L., Holland, S. M., Ochs, H., Quie, P., Buckley, R. H., Foster, C. B., Chanock, S. J. and Dickler, H. (2000) Chronic granulomatous disease: Report on a national registry of 368 patients. Medicine (Baltimore) 79, 155-169
13. Dennis, C. G., Greco, W. R., Brun, Y., Youn, R., Slocum, H. K., Bernacki, R. J., Lewis, R., Wiederhold, N., Holland, S. M., Petraitiene, R., Walsh, T. J. and Segal, B. H. (2006) Effect of amphotericin B and micafungin combination on survival, histopathology, and fungal burden in experimental aspergillosis in the p47phox-/- mouse model of chronic granulomatous disease. Antimicrob. Agents Chemother. 50, 422-427
14. Bignell, E., Negrete-Urtasun, S., Calcagno, A. M., Arst, H. N. Jr., Rogers, T. and Haynes, K. (2005) Virulence comparisons of Aspergillus nidulans mutants are confounded by the inflammatory response of p47phox-/- mice. Infect. Immun. 73, 5204-5207
15. Morgenstern, D. E., Gifford, M. A., Li, L. L., Doerschuk, C. M. and Dinauer, M. C. (1997) Absence of respiratory burst in X-linked chronic granulomatous disease mice leads to abnormalities in both host defense and inflammatory response to Aspergillus fumigatus. J. Exp. Med. 185, 207-218
16. Schappi, M., Deffert, C., Fiette, L., Gavazzi, G., Herrmann, F., Belli, D. and Krause, K. H. (2008) Branched fungal beta-glucan causes hyperinflammation and necrosis in phagocyte NADPH oxidase-deficient mice. J. Pathol. 214, 434-444
17. Romani, L., Fallarino, F., De Luca, A., Montagnoli, C., D'Angelo, C., Zelante, T., Vacca, C., Bistoni, F., Fioretti, M. C., Grohmann, U., Segal, B. H. and Puccetti, P. (2008) Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease. Nature 451, 211-215
18. Romani, L., Zelante, T., De Luca, A., Bozza, S., Bonifazi, P., Moretti, S., D'Angelo, C., Giovannini, G., Bistoni, F., Fallarino, F. and Puccetti, P. (2008) Indoleamine 2,3-dioxygenase (IDO) in inflammation and allergy to Aspergillus. Med. Mycol. 12, 1-8
19. Puccetti, P. and Grohmann, U. (2007) IDO and regulatory T cells: A role for reverse signalling and non-canonical NF-kappaB activation. Nat. Rev. Immunol. 7, 817-823
20. Gaffen, S. L., Kramer, J. M., Yu, J. J. and Shen, F. (2006) The IL-17 cytokine family. Vitam. Horm. 74, 255-282
21. Ley, K., Smith, E. and Stark, M. A. (2006) IL-17A-producing neutrophil-regulatory Tn lymphocytes. Immunol. Res. 34, 229-242
22. Romani, L., Zelante, T., De Luca, A., Fallarino, F. and Puccetti, P. (2008) IL-17 and therapeutic kynurenines in pathogenic inflammation to fungi. J. Immunol. 180, 5157-5162
23. Kastelein, R. A., Hunter, C. A. and Cua, D. J. (2007) Discovery and biology of IL-23 and IL-27: Related but functionally distinct regulators of inflammation. Annu. Rev. Immunol. 25, 221-242
24. Montagnoli, C., Fallarino, F., Gaziano, R., Bozza, S., Bellocchio, S., Zelante, T., Kurup, W. P., Pitzurra, L., Puccetti, P. and Romani, L. (2006) Immunity and tolerance to Aspergillus involve functionally distinct regulatory T cells and tryptophan catabolism. J. Immunol. 176, 1712-1723
25. Zelante, T., De Luca, A., Bonifazi, P., Montagnoli, C., Bozza, S., Moretti, S., Belladonna, M. L., Vacca, C., Conte, C., Mosci, P., Bistoni, F., Puccetti, P., Kastelein, R. A., Kopf, M. and Romani, L. (2007) IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance. Eur. J. Immunol. 37, 2695-2706
26. George-Chandy, A., Nordstrom, I., Nygren, E., Jonsson, I. M., Postigo, J., Collins, L. V. and Eriksson, K. (2008) Th17 development and autoimmune arthritis in the absence of reactive oxygen species. Eur. J. Immunol. 38, 1118-1126
27. Jackson, S. H., Devadas, S., Kwon, J., Pinto, L. A. and Williams, M. S. (2004) T cells express a phagocyte-type NADPH oxidase that is activated after T cell receptor stimulation. Nat. Immunol. 5, 818-827
28. Wilson, N. J., Boniface, K., Chan, J. R., McKenzie, B. S., Blumenschein, W. M., Mattson, J. D., Basham, B., Smith, K., Chen, T., Morel, F., Lecron, J. C., Kastelein, R. A., Cua, D. J., McClanahan, T. K., Bowman, E. P. and de Waal Malefyt, R. (2007) Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nat. Immunol 8, 950-957
29. Liang, S. C., Tan, X. Y., Luxenberg, D. P., Karim, R., Dunussi-Joannopoulos, K., Collins, M. and Fouser, L. A. (2006) Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides. J. Exp. Med. 203, 2271-2279
30. Kao, C. Y., Chen, Y., Thai, P., Wachi, S., Huang, F., Kim, C., Harper, R. W. and Wu, R. (2004) IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways. J. Immunol. 173, 3482-3491
31. Porro, G. A., Lee, J. H., de Azavedo, J., Crandall, I., Whitehead, T., Tullis, E., Ganz, T., Liu, M., Slutsky, A. S. and Zhang, H. (2001) Direct and indirect bacterial killing functions of neutrophil defensins in lung explants. Am. J. Physiol. Lung Cell. Mol. Physiol. 281, L1240-1247
32. Stevens, D. A., Moss, R. B., Kurup, V. P., Knutsen, A. P., Greenberger, P., Judson, M. A., Denning, D. W., Crameri, R., Brody, A. S., Light, M., Skov, M., Maish, W., Mastella, G., Participants in the Cystic Fibrosis Foundation Consensus Conference (2003) Allergic bronchopulmonary aspergillosis in cystic fibrosis - State of the art: Cystic Fibrosis Foundation Consensus Conference. Clin. Infect. Dis. 37 Suppl 3, S225-264
33. Bals, R., Weiner, D. J., Meegalla, R. L., Accurso, F. and Wilson, J. M. (2001) Salt-independent abnormality of antimicrobial activity in cystic fibrosis airway surface fluid. Am. J. Respir. Cell. Mol. Biol. 25, 21 -25
34. Moraes, T. J., Plumb, J., Martin, R., Vachon, E., Cherepanov, V., Koh, A., Loeve, C., Jongstra-Bilen, J., Zurawska, J. H., Kus, J. V., Burrows, L. L., Grinstein, S. and Downey, G. P. (2006) Abnormalities in the pulmonary innate immune system in cystic fibrosis. Am. J. Respir. Cell. Mol. Biol. 34, 364-374
35. Soong, L. B., Ganz, T., Ellison, A. and Caughey, G. H. (1997) Purification and characterization of defensins from cystic fibrosis sputum. Inflamm. Res. 46, 98 -102
36. Dubin, P. J., McAllister, F. and Kolls, J. K. (2007) Is cystic fibrosis a TH17 disease? Inflamm. Res. 56, 221-227
37. Horwitz, M. E., Barrett, A. J., Brown, M. R., Carter, C. S., Childs, R., Gallin, J. I., Holland, S. M., Linton, G. F., Miller, J. A., Leitman, S. F., Read, E. J. and Malech, H. L. (2001) Treatment of chronic granulomatous disease with nonmyeloablative conditioning and a T-cell-depleted hematopoietic allograft. N. Engl. J. Med. 344, 881-888
38. Malech, H. L., Maples, P. B., Whiting-Theobald, N., Linton, G. F., Sekhsaria, S., Vowells, S. J., Li, F., Miller, J. A., DeCarlo, E., Holland, S. M., Leitman, S. F., Carter, C S., Butz, R. E., Read, E. J., Fleisher, T. A., Schneiderman, R. D., Van Epps, D. E., Spratt, S. K., Maack, C. A., Rokovich, J. A., Cohen, L. K. and Gallin, J. I. (1997) Prolonged production of NADPH oxidase-corrected granulocytes after gene therapy of chronic granulomatous disease. Proc. Natl. Acad. Sci. USA. 94, 12133-12138
39. Ott, M. G., Schmidt, M., Schwarzwaelder, K., Stein, S., Siler, U., Koehl, U., Glimm, H., Kühlcke, K., Schilz, A., Kunkel, H., Naundorf, S., Brinkmann, A., Deichmann, A., Fischer, M., Ball, C., Pilz, I., Dunbar, C., Du, Y., Jenkins, N. A., Copeland, N. G., Lüthi, U., Hassan, M., Thrasher, A. J., Hoelzer, D., von Kalle, C., Seger, R. and Grez, M. (2006) Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1. Nat. Med. 12, 401-409
40. Macchiarulo, A., Camaioni, E., Nuti, R. and Pellicciari, R. (2008) Highlights at the gate of tryptophan catabolism: A review on the mechanisms of activation and regulation of indoleamine 2,3-dioxygenase (IDO), a novel target in cancer disease. Amino Acids [Epub ahead of print]