Time-Course of contrast enhancement in spleen and liver with exia 160, fenestra LC, and VC

Molecular Imaging and Biology

Volumn 11, Issue 2, 2009, Pages 128-135

  Willekens, Inneke ^a,b   Lahoutte, Tony ^a,b   Buls, Nico ^b   Vanhove, Christian ^b   Deklerck, Rudi ^a   Bossuyt, Axel ^a,b   Mey, Johan ^b  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^b UNIVERSITY HOSPITAL BRUSSELS   (Belgium)

Author keywords

C57BL 6 mice; CT contrast agent; Micro CT

Indexed keywords

CONTRAST MEDIUM; EXIA 160; FENESTRA LC; FENESTRA VC; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; C57BL 6 MOUSE; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DRUG CLEARANCE; DRUG HALF LIFE; LIVER SCINTISCANNING; MALE; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN SCINTISCANNING;

ANIMALS; CONTRAST MEDIA; IMAGE PROCESSING, COMPUTER-ASSISTED; LIVER; MALE; METABOLIC CLEARANCE RATE; MICE; MICE, INBRED C57BL; NONLINEAR DYNAMICS; SPLEEN; TIME FACTORS; X-RAY MICROTOMOGRAPHY;

ANIMALIA; MUS;

EID: 60049101445     PISSN: 15361632     EISSN: 18602002     Source Type: Journal    
DOI: 10.1007/s11307-008-0186-8     Document Type: Article

References (28)

1. Wolbarst AB, Hendee WR (2006) Evolving and experimental technologies in medical imaging. Radiology 238:16-39
2. Badea C, Hedlund LW, Johnson GA (2004) Micro-CT with respiratory and cardiac gating. Med Phys 31(12):3324-3329
3. Deroose CM, De A, Loening AM, Chow PL et al (2007) Multimodality imaging of tumor xenografts and metastases in mice with combined small-animal PET, small-animal CT, and bioluminescence imaging. J Nucl Med 48:295-303
4. De Clerck NM, Meurrens K, Weiler H et al (2004) High-resolution X-ray microtomography for the detection of lung tumors in living mice. Neoplasia 6(4):374-379
5. Paulus MJ, Gleason SS, Kennel SJ et al (2000) High resolution X-ray computed tomography: An emerging tool for small animal cancer research. Neoplasia 2(1-2):62-70
6. Lewis JS, Achilefu S, Garbow JR et al (2002) Small animal imaging: current technology and perspectives for oncological imaging. Eur J Cancer 38:2173-2188
7. Weissleder R, Mahmood U (2001) Molecular imaging. Radiology 219:316-333
8. Hu J, Haworth ST, Molthen RC, Dawson CA (2004) Dynamic small animal lung imaging via a postacquisition respiratory gating technique using micro-cone beam computed tomography. Acad Radiol 11:961-970
9. Stenström M, Olander B, Carlsson CA et al (1998) The use of microtomography to monitor morphological changes in small animals. Appl Radiat Isot 49(5/6):565-570
10. Cavanaugh D, Johnson E, Price RE et al (2004) In vivo respiratory-gated micro-CT imaging in small-animal oncology models. Mol Imaging 3(1):55-62
11. Holdsworth DW, Thornton MM (2002) Micro-CT in small animal and specimen imaging. Trends Biotechnol 20(8):34-39
12. Massoud TF, Gambhir SS (2003) Molecular imaging in living subjects: seeing fundamental biological processes in a new light. Genes Devl 17(5):545-580
13. Ford NL, Graham KC, Groom AC et al (2006) Time-course characterization of the computed tomography contrast enhancement of an iodinated blood-pool contrast agent in mice using a volumetric flat-panel equipped computed tomography scanner. Invest Radiol 41:384-390
14. Kao C-Y, Hoffman EA, Beck KC et al (2003) Long-residence-time nano-scale liposomal iohexol for X-ray-based blood pool imaging. Acad Radiol 10:475-483
15. Mukundan S, Ghaghada KB, Badea CT et al (2006) A liposomal nanoscale contrast agent for preclinical CT in mice. AJR 186:300-307
16. Weichert JP, Longino MA, Bakan DA et al (1995) Polyiodinated triglyceride analogs as potential computed tomography imaging agents for the liver. J Med Chem 38:636-646
17. Weichert JP, Lee FT Jr, Chosy SG et al (2000) Combined hepato-selective and blood-pool contrast agents for the CT detection of experimental liver tumors in rabbits. Radiology 216:865-871
18. Bakan DA, Weichert JP, Longino MA et al (2000) Polyiodinated triglyceride lipid emulsions for use as hepatoselective contrast agents in CT: Effects of physiochemical properties on biodistribution and imaging profiles. Invest Radiol 35:158-169
19. Weber SM, Peterson KA, Durkee B et al (2004) Imaging of murine liver tumor using micro-CT with a hepatocyte-selective contast agent: Accuracy is depentdent on adequate contrast enhancement. J Surg Research 119:41-45
20. Weichert JP, Lee FT Jr, Longino MA et al (1998) Lipid-based blood-pool CT imaging of the liver. Acad Radiol 5(Suppl 1):S16-S19
21. Bakan DA, Longino MA, Weichert JP et al (1996) Physicochemical characterization of a synthetic lipid emulsion for hepato-selective delivery of lipophilic compounds: Application to polyiodinated triglycerides as contrast agents for computed tomography. J Pharm Sciences 85(9):908-914
22. Loening AM, Gambhir SS (2003) Amide: A free software tool for multimodality medical image analysis. Mol Imaging 2(3):131-137
23. Desser TS, Rubin DL, Muller H et al (1999) Blood pool and liver enhancement in CT with liposomal iodixanol: Comparison with iohexol. Acad Radiol 6:176-183
24. Torchilin VP, Frank-Kamenetsky MD, Wolf GL (1999) CT visualization of blood pool in rats by using long-circulating, iodine-containing micelles. Acad Radiol 6:61-65
25. Suckow CE, Stout DB (2008) MicroCT liver contrast agent enhancement over time, dose, and mouse strain. Mol Imaging Biol 10(2):114-120
26. Ohta S, Lai EW, Morris JC et al (2006) MicroCT for high-resolution imaging of ectopic pheochromocytoma tumors in the liver of nude mice. Int J Cancer 119:2236-2241
27. Almajdub M, Nejjari M, Poncet G et al (2007) In-vivo high-resolution X-ray microtomography for liver and spleen tumor assessment in mice. Contrast Media Mol Imaging 2:88-93
28. Walters EB, Panda K, Bankson JA et al (2004) Improved method of in vivo respiratory-gated micro-CT imaging. Phys Med Biol 49:4163-4172