Long-residence-time nano-scale liposomal iohexol for x-ray-based blood pool imaging

Academic Radiology

Volumn 10, Issue 5, 2003, Pages 475-483

  Kao, Chen Yu ^a   Hoffman, Eric A ^b,c   Beck, Kenneth C ^b   Bellamkonda, Ravi V ^a   Annapragada, Ananth V ^d,e  

^a Case Western Reserve University   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c IA United States   (United States)

^d CLEVELAND STATE UNIVERSITY   (United States)

^e Cleveland State University   (United States)

Author keywords

Computed tomography (CT), contrast media; Contrast media, experimental studies

Indexed keywords

BUFFER; CONTRAST MEDIUM; IODINE; IOHEXOL; LIPID; LIPOSOME; PHOSPHATE;

ANIMAL EXPERIMENT; AORTA; ARTICLE; BLOOD; BODY WEIGHT; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST ENHANCEMENT; DIAGNOSTIC IMAGING; DRUG CLEARANCE; DRUG FORMULATION; DRUG STABILITY; ENCAPSULATION; EXPERIMENTAL MODEL; FEMALE; HUMAN; IMAGING; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CORTEX; LIVER; NEPHROTOXICITY; NONHUMAN; PLASMA; PRIORITY JOURNAL; RABBIT;

EID: 0037740983     PISSN: 10766332     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1076-6332(03)80055-7     Document Type: Article

References (20)

1. Klingenbeck-Regn K, Schaller S, Flohr T, Ohnesorge B, Kopp AF, Baum U. Subsecond multi-slice computed tomography: basics and applications. Eur J Radiol 1999; 31:110-124.
2. Almen T. New media: experience from 10 years of development of water-soluble nonionic contrast media. Invest Radiol 1980; 15(suppl): S283-S288.
3. Mattrey RF. Blood-pool contrast media are the ideal agents for computed tomography. Invest Radiol 1991; 26(suppl 1):S55-S56; (discussion) S60-S64.
4. Vera DR, Mattrey RF. A molecular CT blood pool contrast agent. Acad Radiol 2002; 9:784-792.
5. Sachse A, Leike JU, Schneider T, et al. Biodistribution and computed tomography blood-pool imaging properties of polyethylene glycolcoated iopromide-carrying liposomes. Invest Radiol 1997; 32:44-50.
6. Folkman J. What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 1990; 82:4-6.
7. Katayama H, Yamaguchi K, Kozuka T, Takashima T, Seez P, Matsuura K. Adverse reactions to ionic and nonionic contrast media. A report from the Japanese Committee on the Safety of Contrast Media. Radiology 1990; 175:621-628.
8. Steinberg EP, Moore RD, Powe NR, et al. Safety and cost effectiveness of high-osmolality as compared with low-osmolality contrast material in patients undergoing cardiac angiography. N Engl J Med 1992; 326:425-430.
9. Chow LC, Rubin GD. CT angiography of the arterial system. Radiol Clin North Am 2002; 40:729-749.
10. Seltzer SE, Davis MA, Adams DF, Shulkin PM, Landis WJ, Havron A. Liposomes carrying diatrizoate: characterization of biophysical properties and imaging applications. Invest Radiol 1984; 19:142-151.
11. Krause W, Leike J, Sachse A, Schuhmann-Giampieri G. Characterization of iopromide liposomes. Invest Radiol 1993; 28:1028-1032.
12. Schmiedl UP, Krause W, Leike J, Sachse A. CT blood pool enhancement in primates with iopromide-carrying liposomes containing soy phosphatidyl glycerol. Acad Radiol 1999; 6:164-169.
13. Leike JU, Sachse A, Rupp K. Characterization of continuously extruded iopromide-carrying liposomes for computed tomography blood-pool imaging. Invest Radiol 2001; 36:303-308.
14. Petersein J, Franke B, Fouillet X, Hamm B. Evaluation of liposomal contrast agents for liver CT in healthy rabbits. Invest Radiol 1999; 34:401-409.
15. Torchilin VP. PEG-based micelles as carriers of contrast agents for different imaging modalities. Adv Drug Deliv Rev 2002; 54:235-252.
16. Idee JM, Port M, Robert P, et al. Preclinical profile of the monodisperse iodinated macromolecular blood pool agent P743. Invest Radiol 2001; 36:41-49.
17. Berthezene Y, Wiart M, Corot C, Violas X, Canet E. CT pulmonary angiography and perfusion: an experimental study using blood pool and nonspecific contrast agent. Acad Radiol 2002; 9(suppl 2):S359-S360.
18. Lasic D. Preparation of liposomes. In: Lasic D, ed. Liposomes: from physics to applications. New York, NY: Elsevier, 1993; 63-107.
19. Torchilin VP. Polymeric contrast agents for medical imaging. Curr Pharm Biotechnol 2000; 1:183-215.
20. DeMario MD, Vogelzang NJ, Janisch L, et al. A phase I study of liposome-formulated cisplatin (SPI-77 (R)) given every 3 weeks in patients with advanced cancer. Ann Oncol 1998; 9(suppl 2):466.