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Volumn 35, Issue 3, 2000, Pages 158-169

Polyiodinated triglyceride lipid emulsions for use as hepatoselective contrast agents in CT: Effects of physicochemical properties on biodistribution and imaging profiles

Author keywords

Computed tomography; Contrast agents; Diagnostic imaging; Liver; Targeted delivery

Indexed keywords

2 OLEOYLGLYCEROL 1,3 BIS[7 (3 AMINO 2,4,6 TRIIODOPHENYL)HEPTANOATE]; CONTRAST MEDIUM; IODINE 125; LIPID EMULSION; UNCLASSIFIED DRUG;

EID: 0034040006     PISSN: 00209996     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004424-200003000-00002     Document Type: Article
Times cited : (27)

References (31)
  • 1
    • 0032039992 scopus 로고    scopus 로고
    • New liposomal liver-specific contrast agent for CT: First human phase 1 clinical trial assessing efficacy and safety
    • Leander P, Hoglund P, Kloster Y, Borseth A. New liposomal liver-specific contrast agent for CT: First human phase 1 clinical trial assessing efficacy and safety. Acad Radiol 1998;5(suppl): S6-S8.
    • (1998) Acad Radiol , vol.5 , Issue.SUPPL.
    • Leander, P.1    Hoglund, P.2    Kloster, Y.3    Borseth, A.4
  • 2
    • 0030639999 scopus 로고    scopus 로고
    • An iodinated lipid emulsion for CT of the liver: Comparison with iohexol in the detection of experimental hepatic metastases
    • Bergman A, Sundin A, Magnusson A. An iodinated lipid emulsion for CT of the liver: comparison with iohexol in the detection of experimental hepatic metastases. Acta Radiol 1997;38:55-60.
    • (1997) Acta Radiol , vol.38 , pp. 55-60
    • Bergman, A.1    Sundin, A.2    Magnusson, A.3
  • 3
    • 33748265702 scopus 로고    scopus 로고
    • Research in CT and MR imaging: 2000 and beyond
    • Balfe DM, Ehman RL. Research in CT and MR imaging: 2000 and beyond. Radiology 1998;207:561-564.
    • (1998) Radiology , vol.207 , pp. 561-564
    • Balfe, D.M.1    Ehman, R.L.2
  • 4
    • 0027645104 scopus 로고
    • Contrast media research: Directions in the 1990's
    • Scholz K. Contrast media research: Directions in the 1990's. Invest Radiol 1993;28:S140-S141.
    • (1993) Invest Radiol , vol.28
    • Scholz, K.1
  • 5
    • 0024339608 scopus 로고
    • Hepatic tumors: Comparison of CT during arterial portography, delayed CT and MR imaging for preoperative evaluation
    • Nelson RC, Chezmar JL, Sugarbaker PH, Bernardino ME. Hepatic tumors: Comparison of CT during arterial portography, delayed CT and MR imaging for preoperative evaluation. Radiology 1989;172: 27-34.
    • (1989) Radiology , vol.172 , pp. 27-34
    • Nelson, R.C.1    Chezmar, J.L.2    Sugarbaker, P.H.3    Bernardino, M.E.4
  • 6
    • 0024516289 scopus 로고
    • Detection of focal hepatic masses: Prospective evaluation with CT, delayed CT, CT during arterial portography and MR imaging
    • Heiken JP, Weyman PJ, Lee JKT, et al. Detection of focal hepatic masses: Prospective evaluation with CT, delayed CT, CT during arterial portography and MR imaging. Radiology 1989;171:47-51.
    • (1989) Radiology , vol.171 , pp. 47-51
    • Heiken, J.P.1    Weyman, P.J.2    Lee, J.K.T.3
  • 7
    • 0019919845 scopus 로고
    • Brominated radiopaque liposomes: Contrast agent for computed tomography of liver and spleen: a preliminary report
    • Caride VJ, Sostman HD, Twickler J, Zacharis H, Orphanoudakis SC, Jaffe CC. Brominated radiopaque liposomes: Contrast agent for computed tomography of liver and spleen: A preliminary report. Invest Radiol 1982;17:381-385.
    • (1982) Invest Radiol , vol.17 , pp. 381-385
    • Caride, V.J.1    Sostman, H.D.2    Twickler, J.3    Zacharis, H.4    Orphanoudakis, S.C.5    Jaffe, C.C.6
  • 9
    • 0026670925 scopus 로고
    • Computed tomographic enhancement of the liver, liver abscesses, spleen, and major vessels with perfluorooctylbromide emulsion: Influence of dosage injection velocity in an animal model
    • Adam G, Gunther RW, Schiffer C, Gortz H, Prescher A, Scherer K. Computed tomographic enhancement of the liver, liver abscesses, spleen, and major vessels with perfluorooctylbromide emulsion: Influence of dosage injection velocity in an animal model. Invest Radiol 1992;27:698-705.
    • (1992) Invest Radiol , vol.27 , pp. 698-705
    • Adam, G.1    Gunther, R.W.2    Schiffer, C.3    Gortz, H.4    Prescher, A.5    Scherer, K.6
  • 10
    • 0024557638 scopus 로고
    • Liver, spleen and vessels: Preliminary clinical results of CT with perfluorooctylbromide
    • Bruneton J-N, Falewee M-N, Francois E, et al. Liver, spleen and vessels: Preliminary clinical results of CT with perfluorooctylbromide. Radiology 1989;170:179-183.
    • (1989) Radiology , vol.170 , pp. 179-183
    • Bruneton, J.-N.1    Falewee, M.-N.2    Francois, E.3
  • 11
    • 0018347250 scopus 로고
    • Development and experimental evaluation of a contrast medium for computed tomographic examination of the liver and spleen
    • Vermess M, Chatterji DC, Doppman JL, Grimes G, Adamson RH. Development and experimental evaluation of a contrast medium for computed tomographic examination of the liver and spleen. J Comput Assist Tomogr 1979;3:25-31.
    • (1979) J Comput Assist Tomogr , vol.3 , pp. 25-31
    • Vermess, M.1    Chatterji, D.C.2    Doppman, J.L.3    Grimes, G.4    Adamson, R.H.5
  • 12
    • 0018371616 scopus 로고
    • Formulation and evaluation of ethiodized oil emulsion for intravenous hepatography
    • Grimes G, Vermess M, Galelli JF, Chatterji DC. Formulation and evaluation of ethiodized oil emulsion for intravenous hepatography. J Pharm Sci 1979;68:52-56.
    • (1979) J Pharm Sci , vol.68 , pp. 52-56
    • Grimes, G.1    Vermess, M.2    Galelli, J.F.3    Chatterji, D.C.4
  • 13
    • 84970479153 scopus 로고
    • Experimental investigation of a new iodinated lipid emulsion for computed tomography of the liver
    • Ivancev K, Lunderquist A, McCuskey R, McCuskey P, Wretlind A. Experimental investigation of a new iodinated lipid emulsion for computed tomography of the liver. Acta Radiol 1989;30:407-413.
    • (1989) Acta Radiol , vol.30 , pp. 407-413
    • Ivancev, K.1    Lunderquist, A.2    McCuskey, R.3    McCuskey, P.4    Wretlind, A.5
  • 14
    • 0031132834 scopus 로고    scopus 로고
    • CT of experimental hepatoma using the hepatocyte-specific lipid emulsion FP 736-03
    • Bergman A, Sundin A, Magnusson A. CT of experimental hepatoma using the hepatocyte-specific lipid emulsion FP 736-03. Acta Radiol 1997;38:400-404.
    • (1997) Acta Radiol , vol.38 , pp. 400-404
    • Bergman, A.1    Sundin, A.2    Magnusson, A.3
  • 15
    • 0029042806 scopus 로고
    • Polyiodinated triglyceride analogs as potential computed tomography imaging agents for the liver
    • Weichert JP, Longino MA, Bakan DA, et al. Polyiodinated triglyceride analogs as potential computed tomography imaging agents for the liver. J Med Chem 1995;38:636-646.
    • (1995) J Med Chem , vol.38 , pp. 636-646
    • Weichert, J.P.1    Longino, M.A.2    Bakan, D.A.3
  • 17
    • 0029952328 scopus 로고    scopus 로고
    • Formulation of polyiodinated triglyceride analogues in a chylomicron remnant-like liver-selective delivery vehicle
    • Longino MA, Bakan DA, Weichert JP, Counsell RE. Formulation of polyiodinated triglyceride analogues in a chylomicron remnant-like liver-selective delivery vehicle. Pharm Res 1996;13:875-879.
    • (1996) Pharm Res , vol.13 , pp. 875-879
    • Longino, M.A.1    Bakan, D.A.2    Weichert, J.P.3    Counsell, R.E.4
  • 18
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipides from animal tissues
    • Folch J, Lees M, Sloane-Stanley GH. A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 1957;226:497-509.
    • (1957) J Biol Chem , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane-Stanley, G.H.3
  • 19
    • 0024402917 scopus 로고
    • Lipoprotein incorporation enhances radioiodinated cholesteryl ester uptake into steroid hormone-secreting tissues
    • Counsell RE, Schwendner SW, Gross MD, Longino MA, McConnell DS. Lipoprotein incorporation enhances radioiodinated cholesteryl ester uptake into steroid hormone-secreting tissues. J Nucl Med 1989;30:1088-1094.
    • (1989) J Nucl Med , vol.30 , pp. 1088-1094
    • Counsell, R.E.1    Schwendner, S.W.2    Gross, M.D.3    Longino, M.A.4    McConnell, D.S.5
  • 20
    • 0027067987 scopus 로고
    • Hepatic clearance of plasma chylomicron remnants
    • Cooper AD. Hepatic clearance of plasma chylomicron remnants. Semin Liver Dis 1992;12:386-396.
    • (1992) Semin Liver Dis , vol.12 , pp. 386-396
    • Cooper, A.D.1
  • 21
    • 0017858669 scopus 로고
    • Rates of removal and degradation of chylomicron remnants by isolated perfused rat liver
    • Cooper AD, Yu PYS. Rates of removal and degradation of chylomicron remnants by isolated perfused rat liver. J Lipid Res 1978;19: 635-643.
    • (1978) J Lipid Res , vol.19 , pp. 635-643
    • Cooper, A.D.1    Yu, P.Y.S.2
  • 22
    • 0017855933 scopus 로고
    • Characterization of the sinusoidal transport process responsible for uptake of chylomicrons by the liver
    • Sherrill BC, Dietschy JM. Characterization of the sinusoidal transport process responsible for uptake of chylomicrons by the liver. J Biol Chem 1978;253:1859-1867.
    • (1978) J Biol Chem , vol.253 , pp. 1859-1867
    • Sherrill, B.C.1    Dietschy, J.M.2
  • 23
    • 0032895028 scopus 로고    scopus 로고
    • Remnant lipoprotein metabolism: Key pathways involving cell-surface heparan sulfate proteoglycans and apolipoprotein E
    • Mahley RW, Ji Z-S. Remnant lipoprotein metabolism: Key pathways involving cell-surface heparan sulfate proteoglycans and apolipoprotein E. J Lipid Res 1999;40:1-16.
    • (1999) J Lipid Res , vol.40 , pp. 1-16
    • Mahley, R.W.1    Ji, Z.-S.2
  • 24
    • 0030661590 scopus 로고    scopus 로고
    • Hepatic uptake of chylomicron remnants
    • Cooper AD. Hepatic uptake of chylomicron remnants. J Lipid Res 1997;38:2173-2192.
    • (1997) J Lipid Res , vol.38 , pp. 2173-2192
    • Cooper, A.D.1
  • 25
    • 0021858187 scopus 로고
    • The liver sieve: Considerations concerning the structure and function of endothelial fenestrae, the sinusoidal wall and the space of Disse
    • Wisse E, De Zanger RB, Charels K, van der Smissen P, McCuskey RS. The liver sieve: Considerations concerning the structure and function of endothelial fenestrae, the sinusoidal wall and the space of Disse. Hepatology 1985;5:683-692.
    • (1985) Hepatology , vol.5 , pp. 683-692
    • Wisse, E.1    De Zanger, R.B.2    Charels, K.3    Van Der Smissen, P.4    McCuskey, R.S.5
  • 27
    • 0029759730 scopus 로고    scopus 로고
    • Physicochemical characterization of a synthetic lipid emulsion for hepatocyte-selective delivery of lipophilic compounds: Application to polyiodinated triglycerides as contrast agents for computed tomography
    • Bakan DA, Longino MA, Weichert JP, Counsell RE. Physicochemical characterization of a synthetic lipid emulsion for hepatocyte-selective delivery of lipophilic compounds: Application to polyiodinated triglycerides as contrast agents for computed tomography. J Pharm Sci 1996;85:908-914.
    • (1996) J Pharm Sci , vol.85 , pp. 908-914
    • Bakan, D.A.1    Longino, M.A.2    Weichert, J.P.3    Counsell, R.E.4
  • 28
    • 0023135981 scopus 로고
    • Liver metastasis detection: Comparative sensitivities of MR imaging and CT scanning
    • Reinig JW, Dwyer AJ, Miller DL, et al. Liver metastasis detection: Comparative sensitivities of MR imaging and CT scanning. Radiology 1987;162:43-47.
    • (1987) Radiology , vol.162 , pp. 43-47
    • Reinig, J.W.1    Dwyer, A.J.2    Miller, D.L.3
  • 29
    • 0021181609 scopus 로고
    • Intralipid effects on reticuloendothelial function
    • Nugent KM. Intralipid effects on reticuloendothelial function. J Leukoc Biol 1984;36:123-132.
    • (1984) J Leukoc Biol , vol.36 , pp. 123-132
    • Nugent, K.M.1
  • 30
    • 0027396084 scopus 로고
    • Investigation of contrast enhancement in CT of the liver: The need for improved methods
    • Dodd GD III, Baron RL. Investigation of contrast enhancement in CT of the liver: The need for improved methods. Am J Roentgenol 1993;160:643-646.
    • (1993) Am J Roentgenol , vol.160 , pp. 643-646
    • Dodd III, G.D.1    Baron, R.L.2
  • 31
    • 0027397087 scopus 로고
    • Contrast material for combined abdominal and pelvic CT: Can cost be reduced by increasing the concentration and decreasing the volume?
    • Baker ME, Beam C, Leder R, Gulliver D, Paine SS, Dunnick NR. Contrast material for combined abdominal and pelvic CT: Can cost be reduced by increasing the concentration and decreasing the volume? Am J Roentgenol 1993;160:637-641.
    • (1993) Am J Roentgenol , vol.160 , pp. 637-641
    • Baker, M.E.1    Beam, C.2    Leder, R.3    Gulliver, D.4    Paine, S.S.5    Dunnick, N.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.