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Volumn 29, Issue 6, 2008, Pages 846-851

The GPR54-kisspeptin complex in reproductive biology: Neuroendocrine significance and implications for ovulation induction and contraception

Author keywords

GnRH; Hypothalamic regulation; Kisspeptin; Pituitary function; Puberty

Indexed keywords

G PROTEIN COUPLED RECEPTOR 54; KISSPEPTIN; MESSENGER RNA; NEUROTRANSMITTER; SEX HORMONE;

EID: 59849119201     PISSN: 0172780X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (9)

References (58)
  • 1
    • 34248383233 scopus 로고    scopus 로고
    • Involvement of anteroventral periventricular metastin/ kisspeptin neurons in estrogen positive feedback action on luteinizing hormone release in female rats
    • Adachi S, Yamada S, Takatsu Y, Matsui H, Kinoshita M, Takase K, et al. (2007) Involvement of anteroventral periventricular metastin/ kisspeptin neurons in estrogen positive feedback action on luteinizing hormone release in female rats. J Reprod Dev 53: 367-78.
    • (2007) J Reprod Dev , vol.53 , pp. 367-378
    • Adachi, S.1    Yamada, S.2    Takatsu, Y.3    Matsui, H.4    Kinoshita, M.5    Takase, K.6
  • 2
    • 37549000647 scopus 로고    scopus 로고
    • KiSS-1 mRNA in adipose tissue is regulated by sex hormones and food intake
    • Brown RE, Imran SA, Ur E, Wilkinson M. (2008) KiSS-1 mRNA in adipose tissue is regulated by sex hormones and food intake. Mol Cell Endocrinol 281: 64-72.
    • (2008) Mol Cell Endocrinol , vol.281 , pp. 64-72
    • Brown, R.E.1    Imran, S.A.2    Ur, E.3    Wilkinson, M.4
  • 3
    • 58149178839 scopus 로고    scopus 로고
    • Basic aspects of the control of GnRH and LH secretions by kisspeptin: Potential applications for better control of fertility in females
    • Caraty A, Franceschini I. (2008) Basic aspects of the control of GnRH and LH secretions by kisspeptin: potential applications for better control of fertility in females. Reprod Dom Anim 43(Suppl 2): 172-8.
    • (2008) Reprod Dom Anim , vol.43 , Issue.SUPPL. 2 , pp. 172-178
    • Caraty, A.1    Franceschini, I.2
  • 4
    • 33750591860 scopus 로고    scopus 로고
    • Expression of hypothalamic KiSS-1 system and rescue of defective gonadotropic responses by kisspeptin in streptozotocin-induced diabetic male rats
    • Castellano JM, Navarro VM, Fernandez-Fernandez R, Roa J, Vigo E, Pineda R, et al. (2006) Expression of hypothalamic KiSS-1 system and rescue of defective gonadotropic responses by kisspeptin in streptozotocin-induced diabetic male rats. Diabetes 55: 2602-10.
    • (2006) Diabetes , vol.55 , pp. 2602-2610
    • Castellano, J.M.1    Navarro, V.M.2    Fernandez-Fernandez, R.3    Roa, J.4    Vigo, E.5    Pineda, R.6
  • 6
    • 33751538038 scopus 로고    scopus 로고
    • Postnatal development of kisspeptin neurons in mouse hypothalamus; sexual dimorphism and projections to gonadotropin-releasing hormone neurons
    • Clarkson J, Herbison AE. (2006) Postnatal development of kisspeptin neurons in mouse hypothalamus; sexual dimorphism and projections to gonadotropin-releasing hormone neurons. Endocrinology 147: 5817-25.
    • (2006) Endocrinology , vol.147 , pp. 5817-5825
    • Clarkson, J.1    Herbison, A.E.2
  • 7
    • 52049083005 scopus 로고    scopus 로고
    • Kisspeptin-GPR54 signalling is essential for preovulatory gonadotropin-releasing hormone neuron activation and the luteinizing hormone surge
    • Clarkson J, d'Anglemont de Tassigny X, Moreno AS, Colledge WH, Herbison AE. (2008) Kisspeptin-GPR54 signalling is essential for preovulatory gonadotropin-releasing hormone neuron activation and the luteinizing hormone surge. J Neurosci 28: 8691-7.
    • (2008) J Neurosci , vol.28 , pp. 8691-8697
    • Clarkson, J.1    d'Anglemont de Tassigny, X.2    Moreno, A.S.3    Colledge, W.H.4    Herbison, A.E.5
  • 8
    • 0026629726 scopus 로고
    • Luteinizing hormone response to an intravenous infusion of substance P in normal men
    • Coiro V, Volpi R, Capretti L, Caiazza A, Marcato A, Bocchi R, et al. (1992) Luteinizing hormone response to an intravenous infusion of substance P in normal men. Metabolism 41: 689-91.
    • (1992) Metabolism , vol.41 , pp. 689-691
    • Coiro, V.1    Volpi, R.2    Capretti, L.3    Caiazza, A.4    Marcato, A.5    Bocchi, R.6
  • 10
  • 12
    • 35349022556 scopus 로고    scopus 로고
    • Kisspeptin-54 stimulates gonadotropin release most potently during the preovulatory phase of the menstrual cycle in women
    • Dhillo WS, Chaudhri OB, Thompson EL, Murphy KG, Patterson M, Ramachandran R, et al. (2007) Kisspeptin-54 stimulates gonadotropin release most potently during the preovulatory phase of the menstrual cycle in women. J Clin Endocrinol Metab 92: 3958-66.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 3958-3966
    • Dhillo, W.S.1    Chaudhri, O.B.2    Thompson, E.L.3    Murphy, K.G.4    Patterson, M.5    Ramachandran, R.6
  • 13
    • 51149105501 scopus 로고    scopus 로고
    • Excitatory effects of the puberty-initiating peptide kisspeptin and group I metabotropic glutamate receptor agonists differentiate two distinct subpopulations of gonadotropin-releasing hormone neurons
    • Dumalska I, Wu M, Morozova E, Liu R, van den Pol A, Alreja M. (2008) Excitatory effects of the puberty-initiating peptide kisspeptin and group I metabotropic glutamate receptor agonists differentiate two distinct subpopulations of gonadotropin-releasing hormone neurons. J Neurosci 28: 8003-13.
    • (2008) J Neurosci , vol.28 , pp. 8003-8013
    • Dumalska, I.1    Wu, M.2    Morozova, E.3    Liu, R.4    van den Pol, A.5    Alreja, M.6
  • 14
    • 33646575920 scopus 로고    scopus 로고
    • Kisspeptin immunoreactive cells of the ovine preoptic area and arcuate nucleus co-express estrogen receptor alpha
    • Franceschini I, Lomet D, Cateau M, Delsol G, Tillet Y, Caraty A. (2006) Kisspeptin immunoreactive cells of the ovine preoptic area and arcuate nucleus co-express estrogen receptor alpha. Neurosci Lett 401: 225-30.
    • (2006) Neurosci Lett , vol.401 , pp. 225-230
    • Franceschini, I.1    Lomet, D.2    Cateau, M.3    Delsol, G.4    Tillet, Y.5    Caraty, A.6
  • 15
    • 13244298245 scopus 로고    scopus 로고
    • Differential expression of 37 selected genes in hormone-refractory prostate cancer using quantitative taqman real-time RT-PCR
    • Fromont G, Chene L, Vidaud M, et al. (2005) Differential expression of 37 selected genes in hormone-refractory prostate cancer using quantitative taqman real-time RT-PCR. Int J Cancer 114: 2174-181.
    • (2005) Int J Cancer , vol.114 , pp. 2174-2181
    • Fromont, G.1    Chene, L.2    Vidaud, M.3
  • 17
    • 0030926108 scopus 로고    scopus 로고
    • Projections of the sexually dimorphic anteroventral periventricular nucleus in the female rat
    • Gu GB, Simerly RB. (1997) Projections of the sexually dimorphic anteroventral periventricular nucleus in the female rat. J Comp Neurol 384: 142-64.
    • (1997) J Comp Neurol , vol.384 , pp. 142-164
    • Gu, G.B.1    Simerly, R.B.2
  • 19
    • 30544450474 scopus 로고    scopus 로고
    • Activation of gonadotropin-releasing hormone neurons by kisspeptin as a neuroendocrine switch for the onset of puberty
    • Han SK, Gottsch ML, Lee KJ, Popa SM, Smith JT, Jakawich SK, et al. (2005) Activation of gonadotropin-releasing hormone neurons by kisspeptin as a neuroendocrine switch for the onset of puberty. J Neurosci 25: 11349-56.
    • (2005) J Neurosci , vol.25 , pp. 11349-11356
    • Han, S.K.1    Gottsch, M.L.2    Lee, K.J.3    Popa, S.M.4    Smith, J.T.5    Jakawich, S.K.6
  • 20
    • 2342536461 scopus 로고    scopus 로고
    • In vivo and in situ modulation of the expression of genes involved in metastasis and angiogenesis in a patient treated with topical imiquimod for melanoma skin metastasis
    • Hesling C, D'Incan M, Mansard S, Franck F, Corbin-Duval A, Chevenet C, et al. (2004) In vivo and in situ modulation of the expression of genes involved in metastasis and angiogenesis in a patient treated with topical imiquimod for melanoma skin metastasis. Br J Dermatol 150: 761-7.
    • (2004) Br J Dermatol , vol.150 , pp. 761-767
    • Hesling, C.1    D'Incan, M.2    Mansard, S.3    Franck, F.4    Corbin-Duval, A.5    Chevenet, C.6
  • 21
    • 13244255747 scopus 로고    scopus 로고
    • Kisspeptin activation of gonadotropin releasing hormone neurons and regulation of KiSS-1 mRNA in the male rat
    • Irwig MS, Fraley GS, Smith JT, Acohido BV, Popa SM, Cunningham MJ, et al. (2004) Kisspeptin activation of gonadotropin releasing hormone neurons and regulation of KiSS-1 mRNA in the male rat. Neuroendocrinology 80: 264-72.
    • (2004) Neuroendocrinology , vol.80 , pp. 264-272
    • Irwig, M.S.1    Fraley, G.S.2    Smith, J.T.3    Acohido, B.V.4    Popa, S.M.5    Cunningham, M.J.6
  • 22
    • 57849139694 scopus 로고    scopus 로고
    • Kisspeptins and the control of gonadotropin secretion in humans
    • doi: 10.1016/ j.peptides.2008.06.026
    • Jayasena CN, Dhillo WS, Bloom SR. (2008) Kisspeptins and the control of gonadotropin secretion in humans. Peptides doi: 10.1016/ j.peptides.2008.06.026.
    • (2008) Peptides
    • Jayasena, C.N.1    Dhillo, W.S.2    Bloom, S.R.3
  • 24
    • 57849133466 scopus 로고    scopus 로고
    • Sexual differentiation and the Kiss1 system: Hormonal and developmental considerations
    • doi: 10.1016/ j.peptides.2008.06.014
    • Kauffman AS. (2008) Sexual differentiation and the Kiss1 system: hormonal and developmental considerations. Peptides doi: 10.1016/ j.peptides.2008.06.014.
    • (2008) Peptides
    • Kauffman, A.S.1
  • 25
    • 24944432237 scopus 로고    scopus 로고
    • Involvement of central metastin in the regulation of preovulatory luteinizing hormone surge and estrous cyclicity in female rats
    • Kinoshita M, Tsukamura H, Adachi S, Matsui H, Uenoyama Y, Iwata K, et al. (2005) Involvement of central metastin in the regulation of preovulatory luteinizing hormone surge and estrous cyclicity in female rats. Endocrinology 146: 4431-6.
    • (2005) Endocrinology , vol.146 , pp. 4431-4436
    • Kinoshita, M.1    Tsukamura, H.2    Adachi, S.3    Matsui, H.4    Uenoyama, Y.5    Iwata, K.6
  • 26
    • 0035860778 scopus 로고    scopus 로고
    • The metastasis suppressor gene KISS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54
    • Kotani M, Detheux M, Vandenbogaerde A, Communi D, Vanderwinden JM, Le Poul E, et al. (2001) The metastasis suppressor gene KISS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54. J Biol Chem 276: 34631-6.
    • (2001) J Biol Chem , vol.276 , pp. 34631-34636
    • Kotani, M.1    Detheux, M.2    Vandenbogaerde, A.3    Communi, D.4    Vanderwinden, J.M.5    Le Poul, E.6
  • 29
    • 0030993620 scopus 로고    scopus 로고
    • Identification of highly expressed genes in metastasis-suppressed chromosome 6/human malignant melanoma hybrid cells using subtractive hybridization and differential display
    • Lee JH, Welch DR. (1997a) Identification of highly expressed genes in metastasis-suppressed chromosome 6/human malignant melanoma hybrid cells using subtractive hybridization and differential display. Int J Cancer 71: 1035-44.
    • (1997) Int J Cancer , vol.71 , pp. 1035-1044
    • Lee, J.H.1    Welch, D.R.2
  • 30
    • 0030956852 scopus 로고    scopus 로고
    • Suppression of metastasis in human breast carcinoma MDA-MB-435 cells after transfection with the metastasis suppressor gene, KISS-1
    • Lee JH, Welch DR. (1997b) Suppression of metastasis in human breast carcinoma MDA-MB-435 cells after transfection with the metastasis suppressor gene, KISS-1. Cancer Res 57: 122384-2387.
    • (1997) Cancer Res , vol.57 , pp. 122384-122387
    • Lee, J.H.1    Welch, D.R.2
  • 31
    • 85157237725 scopus 로고    scopus 로고
    • Lents C, Barb C. (2007) Stimulatory actions of kisspeptin on gonadotropin secretion in prepubertal swine. Biol Reprod (Spec. Iss.) 105;abstract no. 125.
    • Lents C, Barb C. (2007) Stimulatory actions of kisspeptin on gonadotropin secretion in prepubertal swine. Biol Reprod (Spec. Iss.) 105;abstract no. 125.
  • 34
    • 33645882953 scopus 로고    scopus 로고
    • Comparative analysis of the effects of ghrelin and unacylated ghrelin on luteinizing hormone secretion in male rats
    • Martini AC, Fernandez-Fernandez R, Tovar S, Navarro VM, Vigo E, Vazquez MJ, et al. (2006) Comparative analysis of the effects of ghrelin and unacylated ghrelin on luteinizing hormone secretion in male rats. Endocrinology 147: 2374-82.
    • (2006) Endocrinology , vol.147 , pp. 2374-2382
    • Martini, A.C.1    Fernandez-Fernandez, R.2    Tovar, S.3    Navarro, V.M.4    Vigo, E.5    Vazquez, M.J.6
  • 35
    • 2942750179 scopus 로고    scopus 로고
    • Peripheral administration of metastin induces marked gonadotropin release and ovulation in the rat
    • Matsui H, Takatsu Y, Kumano S, Matsumoto H, Ohtaki T. (2004) Peripheral administration of metastin induces marked gonadotropin release and ovulation in the rat. Biochem Biophys Res Commun 320: 383-8.
    • (2004) Biochem Biophys Res Commun , vol.320 , pp. 383-388
    • Matsui, H.1    Takatsu, Y.2    Kumano, S.3    Matsumoto, H.4    Ohtaki, T.5
  • 36
    • 33845885316 scopus 로고    scopus 로고
    • Kisspeptins are novel potent vasoconstrictors in humans, with a discrete localization of their receptor, G protein-coupled receptor 54, to atherosclerosis-prone vessels
    • Mead EJ, Maguire JJ, Kuc RE, Davenport AP. (2007) Kisspeptins are novel potent vasoconstrictors in humans, with a discrete localization of their receptor, G protein-coupled receptor 54, to atherosclerosis-prone vessels. Endocrinology 148: 140-7.
    • (2007) Endocrinology , vol.148 , pp. 140-147
    • Mead, E.J.1    Maguire, J.J.2    Kuc, R.E.3    Davenport, A.P.4
  • 37
    • 13444255980 scopus 로고    scopus 로고
    • Kisspeptin directly stimulates gonadotropin-releasing hormone release via G protein-coupled receptor 54
    • Messager S, Chatzidaki EE, Ma D, Hendrick AG, Zahn D, Dixon J., et al. (2005) Kisspeptin directly stimulates gonadotropin-releasing hormone release via G protein-coupled receptor 54. Proc Natl Acad Sci USA 102: 1761-6.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 1761-1766
    • Messager, S.1    Chatzidaki, E.E.2    Ma, D.3    Hendrick, A.G.4    Zahn, D.5    Dixon, J.6
  • 38
    • 13844301056 scopus 로고    scopus 로고
    • Sexual differentiation of the vertebrate nervous system
    • Morris JA, Jordan CL, Breedlove SM. (2004) Sexual differentiation of the vertebrate nervous system. Nat Neurosci 7: 1034-9.
    • (2004) Nat Neurosci , vol.7 , pp. 1034-1039
    • Morris, J.A.1    Jordan, C.L.2    Breedlove, S.M.3
  • 40
    • 32944469603 scopus 로고    scopus 로고
    • The KISS1 metastasis suppressor: Mechanistic insights and clinical utility
    • Nash KT, Welch DR. (2006) The KISS1 metastasis suppressor: mechanistic insights and clinical utility. Front Biosci 11: 647-59.
    • (2006) Front Biosci , vol.11 , pp. 647-659
    • Nash, K.T.1    Welch, D.R.2
  • 41
    • 33847784034 scopus 로고    scopus 로고
    • KISS1 metastasis suppressor secretion, multiple organ metastasis suppression, and maintenance of tumor dormancy
    • Nash KT, Phadke PA, Navenot J-M, Hurst DR, Accavitti-Loper MA, Sztul E, et al. (2007) KISS1 metastasis suppressor secretion, multiple organ metastasis suppression, and maintenance of tumor dormancy. J Natl Cancer Inst 99: 309-21.
    • (2007) J Natl Cancer Inst , vol.99 , pp. 309-321
    • Nash, K.T.1    Phadke, P.A.2    Navenot, J.-M.3    Hurst, D.R.4    Accavitti-Loper, M.A.5    Sztul, E.6
  • 42
    • 20144372084 scopus 로고    scopus 로고
    • Effects of KiSS-1 peptide, the natural ligand of GPR54, on follicle-stimulating hormone secretion in the rat
    • Navarro VM, Castellano JM, Fernandez-Fernandez R, Tovar S, Roa J, Mayen A, et al. (2005) Effects of KiSS-1 peptide, the natural ligand of GPR54, on follicle-stimulating hormone secretion in the rat. Endocrinology 146: 1689-97.
    • (2005) Endocrinology , vol.146 , pp. 1689-1697
    • Navarro, V.M.1    Castellano, J.M.2    Fernandez-Fernandez, R.3    Tovar, S.4    Roa, J.5    Mayen, A.6
  • 43
    • 0035978639 scopus 로고    scopus 로고
    • Metastasis suppressor gene KISS-1 encodes peptide ligand of a G-protein-coupled receptor
    • Ohtaki T, Shintani Y, Honda S, Matsumoto H, Hori A, Kanehashi K, et al. (2001) Metastasis suppressor gene KISS-1 encodes peptide ligand of a G-protein-coupled receptor. Nature 411: 613-7.
    • (2001) Nature , vol.411 , pp. 613-617
    • Ohtaki, T.1    Shintani, Y.2    Honda, S.3    Matsumoto, H.4    Hori, A.5    Kanehashi, K.6
  • 44
    • 33645460166 scopus 로고    scopus 로고
    • Administration of kisspeptin-54 into discrete regions of the hypothalamus potently increases plasma luteinising hormone and testosterone in male adult rats
    • Patterson M, Murphy KG, Thompson EL, Patel S, Ghatei MA, Bloom SR. (2006) Administration of kisspeptin-54 into discrete regions of the hypothalamus potently increases plasma luteinising hormone and testosterone in male adult rats. J Neuroendocrinol 18: 349-54.
    • (2006) J Neuroendocrinol , vol.18 , pp. 349-354
    • Patterson, M.1    Murphy, K.G.2    Thompson, E.L.3    Patel, S.4    Ghatei, M.A.5    Bloom, S.R.6
  • 45
    • 0013693801 scopus 로고
    • Puberty in monkeys is triggered by chemical stimulation of the hypothalamus
    • Plant TM, Gay VL, Marshall GR, Arslan M. (1989) Puberty in monkeys is triggered by chemical stimulation of the hypothalamus. Proc Natl Acad Sci USA 86: 2506-10.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 2506-2510
    • Plant, T.M.1    Gay, V.L.2    Marshall, G.R.3    Arslan, M.4
  • 49
    • 39749129636 scopus 로고    scopus 로고
    • Kisspeptin-13 inhibits insulin secretion without affecting glucagon or somatostatin release: Study in the perfused rat pancreas
    • Silvestre RA, Egido EM, Hernandez R, Marco J. (2008) Kisspeptin-13 inhibits insulin secretion without affecting glucagon or somatostatin release: study in the perfused rat pancreas. J Endocrinol 196: 283-90.
    • (2008) J Endocrinol , vol.196 , pp. 283-290
    • Silvestre, R.A.1    Egido, E.M.2    Hernandez, R.3    Marco, J.4
  • 50
    • 0036308456 scopus 로고    scopus 로고
    • Wired for reproduction: Organisation and development of sexually dimorphic circuits in the mammalian forebrain
    • Simenly RB. (2002) Wired for reproduction: organisation and development of sexually dimorphic circuits in the mammalian forebrain. Annu Rev Neurosci 25: 507-36.
    • (2002) Annu Rev Neurosci , vol.25 , pp. 507-536
    • Simenly, R.B.1
  • 52
    • 33847008349 scopus 로고    scopus 로고
    • KiSS-1 messenger ribonucleic acid expression in the hypothalamus of the ewe is regulated by sex steroids and season
    • Smith JT, Clay CM, Caraty A, Clarke IJ. (2007a) KiSS-1 messenger ribonucleic acid expression in the hypothalamus of the ewe is regulated by sex steroids and season. Endocrinology 148: 1150-7.
    • (2007) Endocrinology , vol.148 , pp. 1150-1157
    • Smith, J.T.1    Clay, C.M.2    Caraty, A.3    Clarke, I.J.4
  • 55
    • 8544235028 scopus 로고    scopus 로고
    • Central and peripheral administration of kisspeptin-10 stimulates the hypothalamic-pituitary-gonadal axis
    • Thompson EL, Patterson M, Murphy KG, Smith KL, Dhillo WS, Todd JF, et al. (2004) Central and peripheral administration of kisspeptin-10 stimulates the hypothalamic-pituitary-gonadal axis. J Neuroendocrinol 16: 850-8.
    • (2004) J Neuroendocrinol , vol.16 , pp. 850-858
    • Thompson, E.L.1    Patterson, M.2    Murphy, K.G.3    Smith, K.L.4    Dhillo, W.S.5    Todd, J.F.6
  • 57
    • 0028029129 scopus 로고
    • Microcell-mediated transfer of chromosome 6 into metastatic human C8161 melanoma cells suppresses metastasis but does not inhibit tumorigenicity
    • Welch DR, Chen P, Miele ME, McGary CT, Bower JM, Weissman BE, et al. (1994) Microcell-mediated transfer of chromosome 6 into metastatic human C8161 melanoma cells suppresses metastasis but does not inhibit tumorigenicity. Oncogene 9: 255-62.
    • (1994) Oncogene , vol.9 , pp. 255-262
    • Welch, D.R.1    Chen, P.2    Miele, M.E.3    McGary, C.T.4    Bower, J.M.5    Weissman, B.E.6


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