메뉴 건너뛰기




Volumn 53, Issue 2, 2009, Pages 182-188

Distinct roles of protease-activated receptors in signal transduction regulation of endothelial nitric oxide synthase

Author keywords

Endothelial cell; Nitric oxide synthase; Protease activated receptor; Thrombin

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; CYCLIC GMP; ENDOTHELIAL NITRIC OXIDE SYNTHASE; LIGAND; NITRIC OXIDE; PEPTIDE; PROTEINASE; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 2; RHO KINASE INHIBITOR; SERINE; THREONINE; THROMBIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; NITRIC OXIDE SYNTHASE; OLIGOPEPTIDE; RHO KINASE; SERYL LEUCYL ISOLEUCYL GLYCYL ARGINYL LEUCINE; SERYL-LEUCYL-ISOLEUCYL-GLYCYL-ARGINYL-LEUCINE;

EID: 59849118445     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.108.125229     Document Type: Article
Times cited : (12)

References (31)
  • 3
    • 0034608013 scopus 로고    scopus 로고
    • Thrombin responses in human endothelial cells. Contributions from receptors other than PARI include the transactivation of PAR2 by thrombin-cleaved PAR1
    • O'Brien PJ, Prevost N, Molino M, Hollinger MK, Woolkalis MJ, Woulfe DS, Brass LF. Thrombin responses in human endothelial cells. Contributions from receptors other than PARI include the transactivation of PAR2 by thrombin-cleaved PAR1. J Biol Chem. 2000;275:13502-13509.
    • (2000) J Biol Chem , vol.275 , pp. 13502-13509
    • O'Brien, P.J.1    Prevost, N.2    Molino, M.3    Hollinger, M.K.4    Woolkalis, M.J.5    Woulfe, D.S.6    Brass, L.F.7
  • 4
    • 0034936715 scopus 로고    scopus 로고
    • Protease-activated receptor (PAR) 1 but not PAR2 or PAR4 mediates endothelium-dependent relaxation to thrombin and trypsin in human pulmonary arteries
    • Hamilton JR, Moffatt JD, Frauman AG, Cocks TM. Protease-activated receptor (PAR) 1 but not PAR2 or PAR4 mediates endothelium-dependent relaxation to thrombin and trypsin in human pulmonary arteries. J Cardiovasc Pharmacol. 2001;38:108-119.
    • (2001) J Cardiovasc Pharmacol , vol.38 , pp. 108-119
    • Hamilton, J.R.1    Moffatt, J.D.2    Frauman, A.G.3    Cocks, T.M.4
  • 5
    • 0037465357 scopus 로고    scopus 로고
    • Protease-activated receptor 2-mediated vasodilatation in humans in vivo: Role of nitric oxide and prostanoids
    • Robin J, Kharbanda R, McLean P, Campbell R, Vallance P. Protease-activated receptor 2-mediated vasodilatation in humans in vivo: role of nitric oxide and prostanoids. Circulation. 2003;107:954-959.
    • (2003) Circulation , vol.107 , pp. 954-959
    • Robin, J.1    Kharbanda, R.2    McLean, P.3    Campbell, R.4    Vallance, P.5
  • 6
    • 0035816730 scopus 로고    scopus 로고
    • Increased expression of protease-activated receptor-2 (PAR2) and PAR4 in human coronary artery by inflammatory stimuli unveils endothelium-dependent relaxations to PAR2 and PAR4 agonists
    • Hamilton JR, Frauman AG, Cocks TM. Increased expression of protease-activated receptor-2 (PAR2) and PAR4 in human coronary artery by inflammatory stimuli unveils endothelium-dependent relaxations to PAR2 and PAR4 agonists. Circ Res. 2001;89:92-98.
    • (2001) Circ Res , vol.89 , pp. 92-98
    • Hamilton, J.R.1    Frauman, A.G.2    Cocks, T.M.3
  • 7
    • 3042730959 scopus 로고    scopus 로고
    • eNOS at a glance
    • Sessa WC. eNOS at a glance. J Cell Sci. 2004;117:2427-2429.
    • (2004) J Cell Sci , vol.117 , pp. 2427-2429
    • Sessa, W.C.1
  • 9
    • 33847072066 scopus 로고    scopus 로고
    • Mechanism of endothelial nitric oxide synthase phosphorylation and activation by thrombin
    • Motley ED, Eguchi K, Patterson MM, Palmer PD, Suzuki H, Eguchi S. Mechanism of endothelial nitric oxide synthase phosphorylation and activation by thrombin. Hypertension. 2007;49:577-583.
    • (2007) Hypertension , vol.49 , pp. 577-583
    • Motley, E.D.1    Eguchi, K.2    Patterson, M.M.3    Palmer, P.D.4    Suzuki, H.5    Eguchi, S.6
  • 11
    • 33748938039 scopus 로고    scopus 로고
    • The regulator of G protein signaling domain of axin selectively interacts with Galphal2 but not Galpha l3
    • Stemmle LN, Fields TA, Casey PJ. The regulator of G protein signaling domain of axin selectively interacts with Galphal2 but not Galpha l3. Mol Pharmacol. 2006;70:1461-1468.
    • (2006) Mol Pharmacol , vol.70 , pp. 1461-1468
    • Stemmle, L.N.1    Fields, T.A.2    Casey, P.J.3
  • 15
    • 21644449969 scopus 로고    scopus 로고
    • Functional selectivity of G protein signaling by agonist peptides and thrombin for the protease-activated receptor-1
    • McLaughlin JN, Shen L, Holinstat M, Brooks JD, Dibenedetto E, Hamm HE. Functional selectivity of G protein signaling by agonist peptides and thrombin for the protease-activated receptor-1. J Biol Chem. 2005;280:25048-25059.
    • (2005) J Biol Chem , vol.280 , pp. 25048-25059
    • McLaughlin, J.N.1    Shen, L.2    Holinstat, M.3    Brooks, J.D.4    Dibenedetto, E.5    Hamm, H.E.6
  • 16
    • 0034306450 scopus 로고    scopus 로고
    • Specificity and mechanism of action of some commonly used protein kinase inhibitors
    • Davies SP, Reddy H, Caivano M, Cohen P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J. 2000;351:95-105.
    • (2000) Biochem J , vol.351 , pp. 95-105
    • Davies, S.P.1    Reddy, H.2    Caivano, M.3    Cohen, P.4
  • 17
    • 0036077667 scopus 로고    scopus 로고
    • Inhibition of rho-kinase-induced myristoylated alanine-rich C kinase substrate (MARCKS) phosphorylation in human neuronal cells by H-1152, a novel and specific Rho-kinase inhibitor
    • Ikenoya M, Hidaka H, Hosoya T, Suzuki M, Yamamoto N, Sasaki Y. Inhibition of rho-kinase-induced myristoylated alanine-rich C kinase substrate (MARCKS) phosphorylation in human neuronal cells by H-1152, a novel and specific Rho-kinase inhibitor. J Neurochem. 2002;81:9-16.
    • (2002) J Neurochem , vol.81 , pp. 9-16
    • Ikenoya, M.1    Hidaka, H.2    Hosoya, T.3    Suzuki, M.4    Yamamoto, N.5    Sasaki, Y.6
  • 18
    • 34547109096 scopus 로고    scopus 로고
    • Distinct Ca2+ requirement for NO production between proteinase-acti-vated receptor 1 and 4 (PARI and PAR4) in vascular endothelial cells
    • Hirano K, Nomoto N, Hirano M, Momota F, Hanada A, Kanaide H. Distinct Ca2+ requirement for NO production between proteinase-acti-vated receptor 1 and 4 (PARI and PAR4) in vascular endothelial cells. J Pharmacol Exp Ther. 2007;322:668-677.
    • (2007) J Pharmacol Exp Ther , vol.322 , pp. 668-677
    • Hirano, K.1    Nomoto, N.2    Hirano, M.3    Momota, F.4    Hanada, A.5    Kanaide, H.6
  • 19
    • 4344628605 scopus 로고    scopus 로고
    • Thrombin and histamine stimulate endothelial nitric-oxide synthase phosphorylation at Ser ll77 via an AMPK mediated pathway independent of PI3K-Akt
    • Thors B, Halldorsson H, Thorgeirsson G. Thrombin and histamine stimulate endothelial nitric-oxide synthase phosphorylation at Ser ll77 via an AMPK mediated pathway independent of PI3K-Akt. FEBS Lett. 2004;573:175-180.
    • (2004) FEBS Lett , vol.573 , pp. 175-180
    • Thors, B.1    Halldorsson, H.2    Thorgeirsson, G.3
  • 20
    • 33746979242 scopus 로고    scopus 로고
    • Thrombin activates AMP-activated protein kinase in endothelial cells via a pathway involving Ca2+/calmodulin-dependent protein kinase kinase beta
    • Stahmann N, Woods A, Carling D, Heller R. Thrombin activates AMP-activated protein kinase in endothelial cells via a pathway involving Ca2+/calmodulin-dependent protein kinase kinase beta. Mol Cell Biol. 2006;26:5933-5945.
    • (2006) Mol Cell Biol , vol.26 , pp. 5933-5945
    • Stahmann, N.1    Woods, A.2    Carling, D.3    Heller, R.4
  • 21
    • 27744573537 scopus 로고    scopus 로고
    • Endothelial thrombomodulin induces Ca2+ signals and nitric oxide synthesis through epidermal growth factor receptor kinase and calmodulin kinase II
    • David-Dufilho M, Millanvoye-Van Brussel E, Topal G, Walch L, Brunet A, Rendu F. Endothelial thrombomodulin induces Ca2+ signals and nitric oxide synthesis through epidermal growth factor receptor kinase and calmodulin kinase II. J Biol Chem. 2005;280:35999-36006.
    • (2005) J Biol Chem , vol.280 , pp. 35999-36006
    • David-Dufilho, M.1    Millanvoye-Van Brussel, E.2    Topal, G.3    Walch, L.4    Brunet, A.5    Rendu, F.6
  • 22
    • 19044372537 scopus 로고    scopus 로고
    • Long-term inhibition of RhoA attenuates vascular contractility by enhancing endothelial NO production in an intact rabbit mesenteric artery
    • Shiga N, Hirano K, Hirano M, Nishimura J, Nawata H, Kanaide H. Long-term inhibition of RhoA attenuates vascular contractility by enhancing endothelial NO production in an intact rabbit mesenteric artery. Circ Res. 2005;96:1014-1021.
    • (2005) Circ Res , vol.96 , pp. 1014-1021
    • Shiga, N.1    Hirano, K.2    Hirano, M.3    Nishimura, J.4    Nawata, H.5    Kanaide, H.6
  • 23
    • 0036892061 scopus 로고    scopus 로고
    • Rho GTPase/Rho kinase negatively regulates endothelial nitric oxide synthase phosphorylation through the inhibition of protein kinase B/Akt in human endothelial cells
    • Ming XF, Viswambharan H, Barandier C, Ruffieux J, Kaibuchi K, Rusconi S, Yang Z. Rho GTPase/Rho kinase negatively regulates endothelial nitric oxide synthase phosphorylation through the inhibition of protein kinase B/Akt in human endothelial cells. Mol Cell Biol. 2002;22:8467-8477.
    • (2002) Mol Cell Biol , vol.22 , pp. 8467-8477
    • Ming, X.F.1    Viswambharan, H.2    Barandier, C.3    Ruffieux, J.4    Kaibuchi, K.5    Rusconi, S.6    Yang, Z.7
  • 25
    • 0035827676 scopus 로고    scopus 로고
    • Phosphorylation of Thr(495) regulates Ca(2+)/calmodulin-dependent endothelial nitric oxide synthase activity
    • Fleming I, Fisslthaler B, Dimmeler S, Kemp BE, Busse R. Phosphorylation of Thr(495) regulates Ca(2+)/calmodulin-dependent endothelial nitric oxide synthase activity. Circ Res. 2001;88:E68-E75.
    • (2001) Circ Res , vol.88
    • Fleming, I.1    Fisslthaler, B.2    Dimmeler, S.3    Kemp, B.E.4    Busse, R.5
  • 26
    • 0242666181 scopus 로고    scopus 로고
    • Phosphorylation of threonine 497 in endothelial nitric-oxide synthase coordinates the coupling of L-arginine metabolism to efficient nitric oxide production
    • Lin MI, Fulton D, Babbitt R, Fleming I, Busse R, Pritchard KA Jr, Sessa WC. Phosphorylation of threonine 497 in endothelial nitric-oxide synthase coordinates the coupling of L-arginine metabolism to efficient nitric oxide production. J Biol Chem. 2003;278:44719-44726.
    • (2003) J Biol Chem , vol.278 , pp. 44719-44726
    • Lin, M.I.1    Fulton, D.2    Babbitt, R.3    Fleming, I.4    Busse, R.5    Pritchard Jr, K.A.6    Sessa, W.C.7
  • 27
    • 2142651737 scopus 로고    scopus 로고
    • Role of protease-activated receptors in the vascular system
    • Hirano K, Kanaide H. Role of protease-activated receptors in the vascular system. J Atheroscler Thromb. 2003;10:211-225.
    • (2003) J Atheroscler Thromb , vol.10 , pp. 211-225
    • Hirano, K.1    Kanaide, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.