Microinjection of lentiviral vectors expressing small interfering RNAs directed against laminin receptor precursor mRNA prolongs the pre-clinical phase in scrapie-infected mice

Journal of General Virology

Volumn 90, Issue 1, 2009, Pages 269-274

  Pflanz, Heike ^a   Vana, Karen ^a   Mitteregger, Gerda ^a   Pace, Claudia ^a   Messow, Diana ^a   Sedlaczek, Cilli ^a   Nikles, Daphne ^a   Kretzschmar, Hans A ^a   Weiss, Stefan F T ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

LAMININ RECEPTOR; LENTIVIRUS VECTOR; MESSENGER RNA PRECURSOR; PRION PROTEIN; SMALL INTERFERING RNA; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENE TARGETING; IN VITRO STUDY; IN VIVO STUDY; INFECTION PREVENTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE; SCRAPIE; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; ANIMAL; C57BL MOUSE; CELL LINE; DRUG ANTAGONISM; GENE VECTOR; GENETICS; HIPPOCAMPUS; LENTIVIRINAE; LONGEVITY; MICROINJECTION; SURVIVAL; TIME;

LENTIVIRUS; MUS;

ANIMALS; CELL LINE; GENETIC VECTORS; HIPPOCAMPUS; LENTIVIRUS; LONGEVITY; MICE; MICE, INBRED C57BL; MICROINJECTIONS; RECEPTORS, LAMININ; RNA, MESSENGER; RNA, SMALL INTERFERING; SCRAPIE; SURVIVAL ANALYSIS; TIME FACTORS;

EID: 59849110855     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.004168-0     Document Type: Article

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