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Volumn 7, Issue 4, 2009, Pages 655-659

Efficient synthesis of heterocyclic compounds using ethenetricarboxylic acid diesters

Author keywords

[No Author keywords available]

Indexed keywords

2-AMINOALCOHOLS; DE PROTECTIONS; DIESTERS; EFFICIENT SYNTHESIS; HETERO-CYCLES; HETEROCYCLIC COMPOUNDS; HETEROCYCLIC SYSTEMS; MICHAEL ACCEPTORS; MORPHOLINE; ONE POTS; ONE-POT REACTIONS; REACTIVE SITES; REGIO-ISOMERS; REGIOCHEMISTRY; STEPWISE METHODS; SYNTHETIC METHODS;

EID: 59849099893     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b818878e     Document Type: Article
Times cited : (12)

References (31)
  • 25
    • 33846609042 scopus 로고    scopus 로고
    • The aqueous workup described in the Experimental section gave only the major products usually The products 7 and 20b are somewhat unstable and the diastereomer ratios sometimes change on standing, possibly due to the reversibility of the amine elimination and addition. The product 5a is always obtained as a single diastereomer.
    • S. Yamazaki M. Yamamoto A. Sumi Tetrahedron 2007 63 2320
    • (2007) Tetrahedron , vol.63 , pp. 2320
    • Yamazaki, S.1    Yamamoto, M.2    Sumi, A.3
  • 28
    • 33646264750 scopus 로고    scopus 로고
    • 2Ph/R′ = H, 23%) were isolated and characterized. Formation of 12′ may arise from decarboxylation. The yields of condensation of 1a and 17 vary sometimes, therefore the optimized conditions were used Similar amine deprotection and subsequent cyclization was also reported:
    • F. Toda H. Takumi M. Nagami K. Tanaka Heterocycles 1998 47 467
    • (1998) Heterocycles , vol.47 , pp. 467
    • Toda, F.1    Takumi, H.2    Nagami, M.3    Tanaka, K.4
  • 29
    • 33745950245 scopus 로고    scopus 로고
    • 2. However, the reaction gave a complex mixture along with the recovered 24d
    • B. J. Turunen G. I. Georg J. Am. Chem. Soc. 2006 128 8702
    • (2006) J. Am. Chem. Soc. , vol.128 , pp. 8702
    • Turunen, B.J.1    Georg, G.I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.