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Volumn 38, Issue 12, 2008, Pages 3339-3353

Availability of autoantigenic epitopes controls phenotype, severity, and penetrance in TCR Tg autoimmune gastritis

Author keywords

Antigen presentation processing; Autoimmunity; TCR; Tg knockout mice

Indexed keywords

AUTOANTIGEN; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; MAJOR HISTOCOMPATIBILITY ANTIGEN; T LYMPHOCYTE RECEPTOR; CATION TRANSPORT PROTEIN; EPITOPE; LYMPHOCYTE ANTIGEN RECEPTOR; PEPTIDE;

EID: 59749101125     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200838584     Document Type: Article
Times cited : (8)

References (47)
  • 1
    • 0028574256 scopus 로고
    • T-cell tolerance and autoimmunity in transgenic models of central and peripheral tolerance
    • Miller, J. F. and Flavell, R. A., T-cell tolerance and autoimmunity in transgenic models of central and peripheral tolerance. Curr. Opin. Immunol. 1994. 6: 892-899.
    • (1994) Curr. Opin. Immunol , vol.6 , pp. 892-899
    • Miller, J.F.1    Flavell, R.A.2
  • 2
    • 0032795286 scopus 로고    scopus 로고
    • Tolerance and autoimmunity in TCR transgenic mice specific for myelin basic protein
    • Goverman, J., Tolerance and autoimmunity in TCR transgenic mice specific for myelin basic protein. Immunol. Rev. 1999. 169: 147-159.
    • (1999) Immunol. Rev , vol.169 , pp. 147-159
    • Goverman, J.1
  • 3
    • 0029759169 scopus 로고    scopus 로고
    • Dysregulation of potentially pathogenic self reactivity is crucial for the manifestation of clinical autoimmunity
    • Kumar, V. and Sercarz, E., Dysregulation of potentially pathogenic self reactivity is crucial for the manifestation of clinical autoimmunity. J. Neurosci. Res. 1996. 45: 334-339.
    • (1996) J. Neurosci. Res , vol.45 , pp. 334-339
    • Kumar, V.1    Sercarz, E.2
  • 4
    • 0035554950 scopus 로고    scopus 로고
    • Autoimmunity provoked by infection: How good is the case for T cell epitope mimicry?
    • Benoist, C. and Mathis, D., Autoimmunity provoked by infection: how good is the case for T cell epitope mimicry? Nat. Immunol. 2001. 2: 797-801.
    • (2001) Nat. Immunol , vol.2 , pp. 797-801
    • Benoist, C.1    Mathis, D.2
  • 5
    • 0024306288 scopus 로고
    • Molecular mimicry as a mechanism for the cause and a probe uncovering etiologic agent(s) of autoimmune disease
    • Oldstone, M. B., Molecular mimicry as a mechanism for the cause and a probe uncovering etiologic agent(s) of autoimmune disease. Curr. Top. Microbiol. Immunol. 1989. 145: 127-135.
    • (1989) Curr. Top. Microbiol. Immunol , vol.145 , pp. 127-135
    • Oldstone, M.B.1
  • 8
    • 0036857530 scopus 로고    scopus 로고
    • The role of suppressor T cells in regulation of immune responses
    • McHugh, R. S. and Shevach, E. M., The role of suppressor T cells in regulation of immune responses. J. Allergy Clin. Immunol. 2002. 110: 693-702.
    • (2002) J. Allergy Clin. Immunol , vol.110 , pp. 693-702
    • McHugh, R.S.1    Shevach, E.M.2
  • 9
    • 0037039379 scopus 로고    scopus 로고
    • Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
    • Steinman, R. M. and Nussenzweig, M. C., Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance. Proc. Natl. Acad. Sci. USA 2002. 99: 351-358.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 351-358
    • Steinman, R.M.1    Nussenzweig, M.C.2
  • 10
    • 0020451946 scopus 로고
    • Study on cellular events in post-thymectomy autoimmune oophoritis in mice. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis
    • Sakaguchi, S., Takahashi, T. and Nishizuka, Y., Study on cellular events in post-thymectomy autoimmune oophoritis in mice. II. Requirement of Lyt-1 cells in normal female mice for the prevention of oophoritis. J. Exp. Med. 1982. 156: 1577-1586.
    • (1982) J. Exp. Med , vol.156 , pp. 1577-1586
    • Sakaguchi, S.1    Takahashi, T.2    Nishizuka, Y.3
  • 11
    • 0034933018 scopus 로고    scopus 로고
    • AT cell receptor transgenic model of severe, spontaneous organ-specific autoimmunity
    • McHugh, R. S., Shevach, E. M., Margulies, D. H. and Natarajan, K., AT cell receptor transgenic model of severe, spontaneous organ-specific autoimmunity. Eur. J. Immunol. 2001. 31: 2094-2103.
    • (2001) Eur. J. Immunol , vol.31 , pp. 2094-2103
    • McHugh, R.S.1    Shevach, E.M.2    Margulies, D.H.3    Natarajan, K.4
  • 12
    • 22544482556 scopus 로고    scopus 로고
    • The relationship between immunodominance, DM editing, and the kinetic stability of MHC class II:pEptide complexes
    • Sant, A. J., Chaves, F. A., Jenks, S. A., Richards, K. A., Menges, P., Weaver, J. M. and Lazarski, C. A., The relationship between immunodominance, DM editing, and the kinetic stability of MHC class II:pEptide complexes. Immunol. Rev. 2005. 207: 261-278.
    • (2005) Immunol. Rev , vol.207 , pp. 261-278
    • Sant, A.J.1    Chaves, F.A.2    Jenks, S.A.3    Richards, K.A.4    Menges, P.5    Weaver, J.M.6    Lazarski, C.A.7
  • 13
    • 0033064551 scopus 로고    scopus 로고
    • Post-thymectomy autoimmune gastritis: Fine specificity and pathogenicity of anti-H/K ATPase-reactive T cells
    • Suri-Payer, E., Amar, A. Z., McHugh, R., Natarajan, K., Margulies, D. H. and Shevach, E. M., Post-thymectomy autoimmune gastritis: Fine specificity and pathogenicity of anti-H/K ATPase-reactive T cells. Eur. J. Immunol. 1999. 29: 669-677.
    • (1999) Eur. J. Immunol , vol.29 , pp. 669-677
    • Suri-Payer, E.1    Amar, A.Z.2    McHugh, R.3    Natarajan, K.4    Margulies, D.H.5    Shevach, E.M.6
  • 15
    • 0029037210 scopus 로고
    • Serial triggering of many T-cell receptors by a few peptide-MHC complexes
    • Valitutti, S., Muller, S., Cella, M., Padovan, E. and Lanzavecchia, A., Serial triggering of many T-cell receptors by a few peptide-MHC complexes. Nature 1995. 375: 148-151.
    • (1995) Nature , vol.375 , pp. 148-151
    • Valitutti, S.1    Muller, S.2    Cella, M.3    Padovan, E.4    Lanzavecchia, A.5
  • 16
    • 22544455376 scopus 로고    scopus 로고
    • The kinetic stability of MHC class II:pEptide complexes is a key parameter that dictates immunodominance
    • Lazarski, C. A., Chaves, F. A., Jenks, S. A.,Wu, S., Richards, K. A., Weaver, J. M. and Sant, A. J., The kinetic stability of MHC class II:pEptide complexes is a key parameter that dictates immunodominance. Immunity 2005. 23: 29-40.
    • (2005) Immunity , vol.23 , pp. 29-40
    • Lazarski, C.A.1    Chaves, F.A.2    Jenks, S.A.3    Wu, S.4    Richards, K.A.5    Weaver, J.M.6    Sant, A.J.7
  • 17
    • 0028588658 scopus 로고
    • Kinetic intermediates in the reactions between peptides and proteins of major histocompatibility complex class II
    • Beeson, C. and McConnell, H. M., Kinetic intermediates in the reactions between peptides and proteins of major histocompatibility complex class II. Proc. Natl. Acad. Sci. USA 1994. 91: 8842-8845.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8842-8845
    • Beeson, C.1    McConnell, H.M.2
  • 18
    • 0024501330 scopus 로고
    • A kinetic intermediate in the reaction of an antigenic peptide and I-Ek
    • Sadegh-Nasseri, S. and McConnell, H. M., A kinetic intermediate in the reaction of an antigenic peptide and I-Ek. Nature 1989. 337: 274-276.
    • (1989) Nature , vol.337 , pp. 274-276
    • Sadegh-Nasseri, S.1    McConnell, H.M.2
  • 19
    • 0034985966 scopus 로고    scopus 로고
    • Two intermediate-avidity cytotoxic T lymphocyte clones with a disparity between functional avidity and MHC tetramer staining
    • Derby, M. A., Wang, J., Margulies, D. H. and Berzofsky, J. A., Two intermediate-avidity cytotoxic T lymphocyte clones with a disparity between functional avidity and MHC tetramer staining. Int. Immunol. 2001. 13: 817-824.
    • (2001) Int. Immunol , vol.13 , pp. 817-824
    • Derby, M.A.1    Wang, J.2    Margulies, D.H.3    Berzofsky, J.A.4
  • 21
  • 22
    • 0032101405 scopus 로고    scopus 로고
    • Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexes
    • Crawford, F., Kozono, H., White, J., Marrack, P. and Kappler, J., Detection of antigen-specific T cells with multivalent soluble class II MHC covalent peptide complexes. Immunity 1998. 8: 675-682.
    • (1998) Immunity , vol.8 , pp. 675-682
    • Crawford, F.1    Kozono, H.2    White, J.3    Marrack, P.4    Kappler, J.5
  • 24
    • 20744449952 scopus 로고    scopus 로고
    • Class II major histocompatibility complexpeptide tetramer staining in relation to functional avidity and T cell receptor diversity in the mouse CD4(+) T cell response to a rheumatoid arthritis-associated antigen
    • Falta, M. T., Fontenot, A. P., Rosloniec, E. F., Crawford, F., Roark, C. L., Bill, J., Marrack, P. et al., Class II major histocompatibility complexpeptide tetramer staining in relation to functional avidity and T cell receptor diversity in the mouse CD4(+) T cell response to a rheumatoid arthritis-associated antigen. Arthritis Rheum. 2005. 52: 1885-1896.
    • (2005) Arthritis Rheum , vol.52 , pp. 1885-1896
    • Falta, M.T.1    Fontenot, A.P.2    Rosloniec, E.F.3    Crawford, F.4    Roark, C.L.5    Bill, J.6    Marrack, P.7
  • 25
    • 0037152162 scopus 로고    scopus 로고
    • Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node
    • Scheinecker, C., McHugh, R., Shevach, E. M. and Germain, R. N., Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node. J. Exp. Med. 2002. 196: 1079-1090.
    • (2002) J. Exp. Med , vol.196 , pp. 1079-1090
    • Scheinecker, C.1    McHugh, R.2    Shevach, E.M.3    Germain, R.N.4
  • 26
    • 0027263559 scopus 로고
    • Dynamics of epithelial cells in the corpus of the mouse stomach. IV. Bidirectional migration of parietal cells ending in their gradual degeneration and loss
    • Karam, S. M., Dynamics of epithelial cells in the corpus of the mouse stomach. IV. Bidirectional migration of parietal cells ending in their gradual degeneration and loss. Anat. Rec. 1993. 236: 314-332.
    • (1993) Anat. Rec , vol.236 , pp. 314-332
    • Karam, S.M.1
  • 27
    • 0030963614 scopus 로고    scopus 로고
    • Induction of Th1 and Th2 CD4+T cell responses: The alternative approaches
    • Constant, S. L. and Bottomly, K., Induction of Th1 and Th2 CD4+T cell responses: The alternative approaches. Annu. Rev. Immunol. 1997. 15: 297-322.
    • (1997) Annu. Rev. Immunol , vol.15 , pp. 297-322
    • Constant, S.L.1    Bottomly, K.2
  • 28
    • 25144476332 scopus 로고    scopus 로고
    • Independent roles for IL-2 and GATA3 in stimulating naive CD4+T cells to generate a Th2-inducing cytokine environment
    • Yamane, H., Zhu, J. and Paul, W. E., Independent roles for IL-2 and GATA3 in stimulating naive CD4+T cells to generate a Th2-inducing cytokine environment. J. Exp. Med. 2005. 202: 793-804.
    • (2005) J. Exp. Med , vol.202 , pp. 793-804
    • Yamane, H.1    Zhu, J.2    Paul, W.E.3
  • 29
    • 1042280959 scopus 로고    scopus 로고
    • Analysis of autoreactive T cells associated with murine collagen-induced arthritis using peptide-MHC multimers
    • Huang, J. C., Vestberg, M., Minguela, A., Holmdahl, R. and Ward, E. S., Analysis of autoreactive T cells associated with murine collagen-induced arthritis using peptide-MHC multimers. Int. Immunol. 2004. 16: 283-293.
    • (2004) Int. Immunol , vol.16 , pp. 283-293
    • Huang, J.C.1    Vestberg, M.2    Minguela, A.3    Holmdahl, R.4    Ward, E.S.5
  • 30
    • 1242338137 scopus 로고    scopus 로고
    • Degenerate recognition of T cell epitopes: Impact of T cell receptor reserve and stability of peptide:MHC complexes
    • Ford, M. L. and Evavold, B. D., Degenerate recognition of T cell epitopes: Impact of T cell receptor reserve and stability of peptide:MHC complexes. Mol. Immunol. 2004. 40: 1019-1025.
    • (2004) Mol. Immunol , vol.40 , pp. 1019-1025
    • Ford, M.L.1    Evavold, B.D.2
  • 31
    • 0035811034 scopus 로고    scopus 로고
    • Kinetics and thermodynamics of T cell receptor-autoantigen interactions in murine experimental autoimmune encephalomyelitis
    • Garcia, K. C., Radu, C. G., Ho, J., Ober, R. J. and Ward, E. S., Kinetics and thermodynamics of T cell receptor-autoantigen interactions in murine experimental autoimmune encephalomyelitis. Proc. Natl. Acad. Sci. USA 2001. 98: 6818-6823.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 6818-6823
    • Garcia, K.C.1    Radu, C.G.2    Ho, J.3    Ober, R.J.4    Ward, E.S.5
  • 33
    • 0034621834 scopus 로고    scopus 로고
    • Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6A resolution
    • Toyoshima, C., Nakasako, M., Nomura, H. and Ogawa, H., Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6A resolution. Nature 2000. 405: 647-655.
    • (2000) Nature , vol.405 , pp. 647-655
    • Toyoshima, C.1    Nakasako, M.2    Nomura, H.3    Ogawa, H.4
  • 34
    • 34248374850 scopus 로고    scopus 로고
    • Analysis of the gastric H,K ATPase for ion pathways and inhibitor binding sites
    • Munson, K., Law, R. J. and Sachs, G., Analysis of the gastric H,K ATPase for ion pathways and inhibitor binding sites. Biochemistry 2007. 46: 5398-5417.
    • (2007) Biochemistry , vol.46 , pp. 5398-5417
    • Munson, K.1    Law, R.J.2    Sachs, G.3
  • 35
    • 28544439150 scopus 로고    scopus 로고
    • Ligand docking in the gastric H+/K+ATPase: Homology modeling of reversible inhibitor binding sites
    • Kim, C. G., Watts, J. A. and Watts, A., Ligand docking in the gastric H+/K+ATPase: Homology modeling of reversible inhibitor binding sites. J. Med. Chem. 2005. 48: 7145-7152.
    • (2005) J. Med. Chem , vol.48 , pp. 7145-7152
    • Kim, C.G.1    Watts, J.A.2    Watts, A.3
  • 36
    • 23444450284 scopus 로고    scopus 로고
    • Insertion of the dibasic motif in the flanking region of a cryptic self-determinant leads to activation of the epitope-specific T cells
    • Zhu, H., Liu, K., Cerny, J., Imoto, T. and Moudgil, K. D., Insertion of the dibasic motif in the flanking region of a cryptic self-determinant leads to activation of the epitope-specific T cells. J. Immunol. 2005. 175: 2252-2260.
    • (2005) J. Immunol , vol.175 , pp. 2252-2260
    • Zhu, H.1    Liu, K.2    Cerny, J.3    Imoto, T.4    Moudgil, K.D.5
  • 37
    • 9644254186 scopus 로고    scopus 로고
    • Increased noncanonical splicing of autoantigen transcripts provides the structural basis for expression of untolerized epitopes
    • Ng, B., Yang, F., Huston, D. P., Yan, Y., Yang, Y., Xiong, Z., Peterson, L. E. et al., Increased noncanonical splicing of autoantigen transcripts provides the structural basis for expression of untolerized epitopes. J. Allergy Clin. Immunol. 2004. 114: 1463-1470.
    • (2004) J. Allergy Clin. Immunol , vol.114 , pp. 1463-1470
    • Ng, B.1    Yang, F.2    Huston, D.P.3    Yan, Y.4    Yang, Y.5    Xiong, Z.6    Peterson, L.E.7
  • 38
    • 24744468198 scopus 로고    scopus 로고
    • A peptide of glutamic acid decarboxylase 65 can recruit and expand a diabetogenic T cell clone, BDC2.5, in the pancreas
    • Dai, Y. D., Jensen, K. P., Lehuen, A., Masteller, E. L., Bluestone, J. A., Wilson, D. B. and Sercarz, E. E., A peptide of glutamic acid decarboxylase 65 can recruit and expand a diabetogenic T cell clone, BDC2.5, in the pancreas. J. Immunol. 2005. 175: 3621-3627.
    • (2005) J. Immunol , vol.175 , pp. 3621-3627
    • Dai, Y.D.1    Jensen, K.P.2    Lehuen, A.3    Masteller, E.L.4    Bluestone, J.A.5    Wilson, D.B.6    Sercarz, E.E.7
  • 39
    • 0026689639 scopus 로고
    • Subjugation of dominant immunogenic determinants within a chimeric peptide
    • Bhardwaj, V., Kumar, V., Geysen, H. M. and Sercarz, E. E., Subjugation of dominant immunogenic determinants within a chimeric peptide. Eur. J. Immunol. 1992. 22: 2009-2016.
    • (1992) Eur. J. Immunol , vol.22 , pp. 2009-2016
    • Bhardwaj, V.1    Kumar, V.2    Geysen, H.M.3    Sercarz, E.E.4
  • 41
    • 33751563311 scopus 로고    scopus 로고
    • Spontaneous large-scale lymphoid neogenesis and balanced autoimmunity versus tolerance in the stomach of H+/ K+-ATPase-reactive TCR transgenic mouse
    • Katakai, T., Nomura, T., Gonda, H., Sugai, M., Agata, Y., Nishio, A., Masuda, T. et al., Spontaneous large-scale lymphoid neogenesis and balanced autoimmunity versus tolerance in the stomach of H+/ K+-ATPase-reactive TCR transgenic mouse. J. Immunol. 2006. 177: 7858-7867.
    • (2006) J. Immunol , vol.177 , pp. 7858-7867
    • Katakai, T.1    Nomura, T.2    Gonda, H.3    Sugai, M.4    Agata, Y.5    Nishio, A.6    Masuda, T.7
  • 42
    • 0035668524 scopus 로고    scopus 로고
    • The level of peptide-MHC complex determines the susceptibility to autoimmune diabetes: Studies in HEL transgenic mice
    • DiPaolo, R. J. and Unanue, E. R., The level of peptide-MHC complex determines the susceptibility to autoimmune diabetes: Studies in HEL transgenic mice. Eur. J. Immunol. 2001. 31: 3453-3459.
    • (2001) Eur. J. Immunol , vol.31 , pp. 3453-3459
    • DiPaolo, R.J.1    Unanue, E.R.2
  • 43
    • 0029979998 scopus 로고    scopus 로고
    • Role of chain pairing for the production of functional soluble IA major histocompatibility complex class II molecules
    • Scott, C. A., Garcia, K. C., Carbone, F. R., Wilson, I. A. and Teyton, L., Role of chain pairing for the production of functional soluble IA major histocompatibility complex class II molecules. J. Exp. Med. 1996. 183: 2087-2095.
    • (1996) J. Exp. Med , vol.183 , pp. 2087-2095
    • Scott, C.A.1    Garcia, K.C.2    Carbone, F.R.3    Wilson, I.A.4    Teyton, L.5
  • 44
    • 0033532631 scopus 로고    scopus 로고
    • pHdependent peptide binding properties of the type I diabetes-associated I-Ag7 molecule: Rapid release of CLIP at an endosomal pH
    • Hausmann, D. H., Yu, B., Hausmann, S. and Wucherpfennig, K. W., pHdependent peptide binding properties of the type I diabetes-associated I-Ag7 molecule: Rapid release of CLIP at an endosomal pH. J. Exp. Med. 1999. 189: 1723-1734.
    • (1999) J. Exp. Med , vol.189 , pp. 1723-1734
    • Hausmann, D.H.1    Yu, B.2    Hausmann, S.3    Wucherpfennig, K.W.4
  • 45
    • 0141958147 scopus 로고    scopus 로고
    • Ex vivo analysis of thymic CD4 T cells in nonobese diabetic mice with tetramers generated from I-A(g7)/class II-associated invariant chain peptide precursors
    • Jang, M. H., Seth, N. P. and Wucherpfennig, K. W., Ex vivo analysis of thymic CD4 T cells in nonobese diabetic mice with tetramers generated from I-A(g7)/class II-associated invariant chain peptide precursors. J. Immunol. 2003. 171: 4175-4186.
    • (2003) J. Immunol , vol.171 , pp. 4175-4186
    • Jang, M.H.1    Seth, N.P.2    Wucherpfennig, K.W.3
  • 47
    • 0032917076 scopus 로고    scopus 로고
    • A minimal peptide substrate in biotin holoenzyme synthetase-catalyzed biotinylation
    • Beckett, D., Kovaleva, E. and Schatz, P. J., A minimal peptide substrate in biotin holoenzyme synthetase-catalyzed biotinylation. Protein Sci. 1999. 8: 921-929.
    • (1999) Protein Sci , vol.8 , pp. 921-929
    • Beckett, D.1    Kovaleva, E.2    Schatz, P.J.3


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