Ligand docking in the gastric H+/K+-ATPase: Homology modeling of reversible inhibitor binding sites

Journal of Medicinal Chemistry

Volumn 48, Issue 23, 2005, Pages 7145-7152

  Kim, Chang G ^a   Watts, Jude A ^a   Watts, Anthony ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3 TRIMETHYL 8 (PENTAFLUOROPHENYLMETHOXY)IMIDAZO[1,2 A]PYRIDINIUM IODIDE; 8 BENZYLOXY 2 METHYLIMIDAZO[1,2 A]PYRIDINE 3 ACETONITRILE; ADENOSINE TRIPHOSPHATASE (CALCIUM); HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; LANSOPRAZOLE; OMEPRAZOLE; PANTOPRAZOLE; PROTON PUMP INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CATALYSIS; DRUG STRUCTURE; ENZYME CONFORMATION; LIGAND BINDING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SIMULATION; SITE DIRECTED MUTAGENESIS; SOLID STATE;

BINDING SITES; CALCIUM-TRANSPORTING ATPASES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; GASTRIC MUCOSA; H(+)-K(+)-EXCHANGING ATPASE; LIGANDS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 28544439150     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm050326o     Document Type: Article

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