Analysis of the gastric H,K ATPase for ion pathways and inhibitor binding sites

Biochemistry

Volumn 46, Issue 18, 2007, Pages 5398-5417

  Munson, Keith ^a   Law, Richard J ^b   Sachs, George ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b LAWRENCE LIVERMORE NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; CONFORMATIONS; ENZYME INHIBITION; MOLECULAR DYNAMICS; REACTION KINETICS;

CATALYTIC CYCLE; ENERGY MINIMIZATION; NAPHTHYRIDINE INHIBITOR;

ADENOSINETRIPHOSPHATE;

ADENOSINE DIPHOSPHATE MAGNESIUM; ADENOSINE TRIPHOSPHATASE (CALCIUM); CALCIUM; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; NAPHTHYRIDINE DERIVATIVE; OUABAIN; POTASSIUM; WATER;

ADDITION REACTION; ARTICLE; BINDING AFFINITY; BINDING SITE; CATALYSIS; CYTOPLASM; ENERGY CONSERVATION; ENZYME ANALYSIS; ENZYME CONFORMATION; ENZYME STRUCTURE; ION CURRENT; ION TRANSPORT; MEMBRANE TRANSPORT; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN DOMAIN; SEQUENCE HOMOLOGY; VESTIBULE;

AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; BINDING, COMPETITIVE; COMPUTER SIMULATION; ENZYME INHIBITORS; GASTRIC MUCOSA; H(+)-K(+)-EXCHANGING ATPASE; ION TRANSPORT; MODELS, MOLECULAR; PROTEIN CONFORMATION; RABBITS; RATS; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; STRUCTURAL HOMOLOGY, PROTEIN; SWINE;

STROPHANTHUS GRATUS;

EID: 34248374850     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi062305h     Document Type: Article

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